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自主机器人使能技术在制造业中的应用（英文）

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Transactions of Nanjing University of Aeronautics and Astronautics 2024年第4期 403-431页

作者： ERD?S Gábor ABAI Kristóf BEREGI Richárd csEMPESZ János csERTEG Tamás GODó Gábor HAJóS Mátyás HáY Borbála HORVáTH Dániel HORVáTH Gergely JUNIKI ádám KEMéNY Zsolt KOVács András NAcsA János PANITI Imre PEDONE Gianfranco takács emma TIPARY Bence ZAHORáN László VáNCZA József 匈牙利研究网络计算机科学与控制研究所布达佩斯经济与技术大学制造科学与技术系 EPIC非盈利创新实验室厄特沃什·罗兰大学

自主制造系统的研究既受益于信息物理融合系统这一新技术的推动，也响应工业实际需求的号召。目前，先进的传感器技术、数字孪生、人工智能和新型通信技术可以支持半结构化工业环境中的自主操作，可实现对生产过程的实时监控、情况识别... 详细信息

自主制造系统的研究既受益于信息物理融合系统这一新技术的推动，也响应工业实际需求的号召。目前，先进的传感器技术、数字孪生、人工智能和新型通信技术可以支持半结构化工业环境中的自主操作，可实现对生产过程的实时监控、情况识别和预测、自动和自适应（重新）规划、团队合作，以及通过学习提高性能。本文总结了实现自主工业机器人技术的主要需求，提出了实现此类系统的通用工作流程，并介绍了HUN-REN SZtakI最近在装配、焊接、打磨、拾取和放置以及机械加工等多个应用领域的广泛实践。这些解决方案的共同点是以通用的数字孪生概念为核心。最后，本文提出实现工业自主机器人解决方案的一般建议，并讨论了未来要研究的一些开放性问题。

关键词：工业机器人自动化数字孪生使能技术

Proteomics of cell-free breast cancer scaffolds identify clinically relevant imprinted proteins and cancer-progressing properties

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Cancer Communications 2024年第6期44卷 695-699页

作者： Anna Gustafsson emma Jonasson Anders Stalberg Goan Landberg Sahlgrenska Center for Cancer Research Department of Laboratory of MedicineInstitute of BiomedicineSahlgrenska Academy at University of GothenburgGothenburgSweden Wallenberg Centre for Molecular and Translational Medicine University of GothenburgGothenburgSweden Department of Clinical Genetics and Genomics Sahlgrenska University HospitalRegion Vatra GoalandGothenburgSweden Department of Clinical Pathology and Genetics Sahlgrenska University HospitalRegion Vatra GoalandGothenburgSweden

The composition of the extracellular tumor microenvironment(TME)has not been fully delineated,limiting the understanding of general cancer-progressing properties within the cancer *** interplay and dynamics between cancer cells and the surrounding structures and cells clearly differ between various subtypes of cancer,adding to the complexity of precision medicine[1].

关键词： cancer clinically breast

Interconnection Gridlock Threatens Transition to Renewable Energy

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Engineering 2024年第5期36卷 3-5页

作者： emma Hiolski Senior Technology Writer

In October 2023,the International Energy Agency(IEA)released a report identifying inadequate grid infrastructure as a key threat to meeting the climate goals laid out by the Paris Agreement[1],the landmark 2015 international treaty in which 196 parties agreed to limit global warming to well below 2℃ above preindustrial levels[2].Importantly,funding for the treaty’s calledfor transition from fossil fuels to clean energy has accelerated[3],with recently legislated massive governmental subsidies and other incentives(e.g.,the Inflation Reduction Act[4])aimed specifically at promoting renewable ***,a commensurate surge in investment in electrical grids has not materialized;instead,it has stagnated for the past decade at around 300 billion USD per year worldwide[1].

关键词： Transition instead massive

Extreme Weather Disruptions and Emergency Preparedness Among Older Adults in Ohio: An Eight-County Assessment

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International Journal of Disaster Risk Science 2024年第2期15卷 213-225页

作者： Smitha Rao Fiona C.Doherty Anthony Traver Marisa Sheldon emma Sakulich Holly Dabelko‑Schoeny College of Social Work The Ohio State UniversityColumbusOH 43210USA Age Friendly Innovation Center College of Social WorkThe Ohio State UniversityColumbusOH 43210USA College of Public Health The Ohio State UniversityColumbusOH 43210USA

The disproportionate risks and impacts of climate change and extreme weather on older adults are increasingly evident. While especially true in disaster-prone areas, human-caused climate change introduces an element of uncertainty even in previously identified “safe” regions such as the Midwestern United States. Using a cumulative disadvantage and vulnerability-informed framework and descriptive statistics from multiple data sources, this article provides an overview of climate impacts, vulnerabilities, and county-level characteristics, focusing on older adults living in Central Ohio. A comparative multiple-case study methodology was used to triangulate regionally representative primary and secondary data sources to examine state and county-level measures of vulnerability, emergency preparedness, and disruptions caused by extreme weather among older adults across eight counties in Central Ohio. Seventy-eight percent of older adults in the sample reported being prepared for emergencies per Federal Emergency Management Agency guidelines. Older adults in Union County reported the highest rates of preparedness, while those in Fayette County reported the lowest. County-level rates of disruption of life activities by extreme weather ranged widely. Among the most rural in the region, Fayette County emerged as uniquely disadvantaged, with the lowest median income, the most vulnerable across multiple social vulnerability dimensions, and the most reported disruptions to life activities from extreme weather. County profiles offer a snapshot of existing vulnerabilities, socioeconomic conditions, special needs, preparedness, and current disruptions among older adults in the region and can inform resource mobilization across community and policy contexts.

关键词： Disaster preparedness Extreme weather Midwestern United States Older adults Regional assessment Social vulnerability

Does Herd Immunity Reduce the Risk of Contracting COVID-19?

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Journal of Biosciences and Medicines 2024年第9期12卷 21-27页

作者： emma Li Unionville High School Kennett Square PA USA

Herd immunity is often considered a measure to protect a whole community or population from disease if the vaccination threshold is met. Using the demographic and COVID-19 infection data from the state of Pennsylvania, United States, the study aimed to determine if herd immunity by vaccination is an effective way to reduce the spread of the COVID-19 virus. The Pennsylvania counties were split into two groups based on qualification of herd immunity: counties that met the COVID-19 herd immunization rate of 70% and counties that did not. The ANOVA test was used to analyze the difference between the groups with and without herd immunity by the COVID-19 vaccine. The results demonstrated that there was no significant statistical difference between counties that did achieve and those that did not achieve the herd immunity threshold for the COVID-19 vaccine. On the other hand, it was observed that there had been a significant decrease in positive cases between 2020 and 2023. This decline can be attributed to the overall protection by the vaccination and adaptability to the disease, not specifically due to herd immunity alone. Ultimately, these outcomes suggest that herd immunity cannot reduce the risk of contracting COVID-19. Increased efforts to get vaccinated should be implemented to protect the general community and a wider scope of age.

关键词： COVID-19 Herd Immunity Vaccine

Methane cracking in molten tin for hydrogen and carbon production—a comparison with homogeneous gas phase process

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Frontiers of Chemical Science and Engineering 2024年第7期18卷 155-166页

作者： emmanuel Busillo Benedetta de Caprariis Maria Paola Bracciale Vittoria Cosentino Martina Damizia Gaetano Iaquaniello emma Palo Paolo De Filippis Chemical Engineering Department Sapienza University of RomeRome 00184Italy NextChem S.p.A. Rome 00156Italy

Methane cracking is considered a bridge technology between gray and green hydrogen production *** this work an experimental study of methane cracking in molten tin is *** tests were conducted in a quartz reactor(i.d.=1.5 cm,L=20 cm)with capillary injection,varying temperature(950–1070℃),inlet methane flow rate(30–60 mL·min^(-1))and tin height(0–20 cm).The influence of the residence time in the tin and in the headspace on methane conversion and on carbon morphology was *** conversions obtained in tin and in the empty reactor were measured and compared with results of detailed kinetic simulations(CRECK).Furthermore,an expression of a global kinetic constant for methane conversion in tin was also *** highest conversion(65%at Q_(0)=30 mL·min^(-1) and t=1070℃)is obtained for homogeneous gas phase reaction due to the long residence time(70 s),the presence of tin leads to a sharp decrease of residence time(1 s),obtaining a conversion of 35%at 1070℃,thus meaning that tin owns a role in the *** characterization(scanning electron microscopy,Raman)reported a change in carbon toward sheet-like structures and an increase of the carbon structural order in the presence of molten tin media.

关键词： methane cracking molten media H2 production carbon morphology

Conducting Polymer-Based e-Refinery for Sustainable Hydrogen Peroxide Production

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Energy & Environmental Materials 2024年第2期7卷 334-342页

作者： Zhixing Wu Penghui Ding Viktor Gueskine Robert Boyd Eric Daniel G■owacki Magnus Odén Xaνier Crispin Magnus Berggren emma M.Björk Mikhail Vagin Nanostructured Materials Department of PhysicsChemistry and Biology(IFM)Linköping UniversitySE 58183LinköpingSweden Laboratory of Organic Electronics Department of Science and Technology(ITN)Linköping UniversitySE 60174NorrköpingSweden

Electrocatalysis enables the industrial transition to sustainable production of chemicals using abundant precursors and electricity from renewable ***-centralized production of hydrogen peroxide(H_(2)O_(2))from water and oxygen of air is highly desirable for daily life and *** report an effective electrochemical refinery(e-refinery)for H_(2)O_(2)by means of electrocatalysis-controlled comproportionation reaction(2_(H)O+o→2HO),feeding pure water and oxygen *** nickel(Ⅱ)oxide(NiO)was used as electrocatalyst for oxygen evolution reaction(OER),producing oxygen at the *** polymer poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)(PEDOT:PSS)drove the oxygen reduction reaction(ORR),forming H_(2)O_(2)on the *** reactions were evaluated in both half-cell and device *** performance of the H_(2)O_(2)e-refinery,assembled on anion-exchange solid electrolyte and fed with pure water,was limited by the unbalanced ionic *** of the operation conditions allowed a conversion efficiency of 80%.

关键词： conducting polymer hydrogen peroxide nickel(Ⅱ)oxide oxygen evolution reaction oxygen reduction reaction

Antigen-specific mRNA lipid nanoparticle platforms for the prevention and treatment of allergy and autoimmune diseases

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BMEMat(BioMedical Engineering Materials) 2024年第2期2卷 61-68页

作者： emma Y.Yim Amanda C.Zhou Yvonne C.Yim Xiang Wang Tian Xia Department of Molecular Cell and Developmental BiologyUniversity of CaliforniaLos AngelesUSA Department of Bioengineering University of CaliforniaLos AngelesUSA Department of Chemistry and Biochemistry University of CaliforniaLos AngelesUSA Division of NanoMedicine Department of MedicineCenter for Environmental Implications of Nanotechnology(UC CEIN)California NanoSystems InstituteUniversity of CaliforniaLos AngelesUSA

While most nanomedicines primarily aim to stimulate the immune system against infections or tumors,there is a growing demand for inducing immune tolerance under certain conditions,such as allergic and autoimmune *** have explored nanotechnology-based strategies to induce immune tolerance in a targeted and specific *** approach involves the use of nanoparticles(NPs)to encapsulate immunosuppressive drugs and/or antigens to educate naïve T cells and promote the generation of antigen-specific regulatory T cells that inhibit immune ***,this approach has certain *** hydrophobicity of proteins or peptides restricts the degree to which they can be encapsulated in NPs,which in turn,affects their loading efficiency and treatment *** the emergence of mRNA lipid nanoparticle(LNP)platforms,there is the possibility of overcoming the limitations of protein and peptide *** date,mRNA LNP systems have been shown to provide organ,cellular,and subcellular targeting for the induction of immune *** method of drug delivery is flexible and scalable that can be customized for a specific patient,resulting in an effective means of administering relevant proteins or epitopes to induce antigen-specific immune *** continued research and development,this technology could offer a safer and more effective alternative to current therapies,ultimately improving the quality of life of patients worldwide.

关键词： allergy autoimmune diseases immune tolerance mRNA lipid nanoparticle nanomedicine

Modern internet search analytics and thyroidectomy:What are patients asking?

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 49-58页

作者： Neeraj Suresh Christian Fritz emma De Ravin Karthik Rajasekaran Department of Otorhinolaryngology–Head&Neck Surgery University of PennsylvaniaPhiladelphiaPennsylvaniaUSA Perelman School of Medicine at the University of Pennsylvania PhiladelphiaPennsylvaniaUSA Leonard Davis Institute of Health Economics University of PennsylvaniaPhiladelphiaPennsylvaniaUSA

Objectives:Thyroidectomy is among the most commonly performed head and neck surgeries,however,limited existing information is available on topics of interest and concern to *** Design:***:***:A search engine optimization tool was utilized to extract metadata on Google‐suggested questions that“People Also Ask”(PAA)pertaining to“thyroidectomy”and“thyroid surgery.”These questions were categorized by Rothwell criteria and topics of *** Journal of the American Medical Association(JAMA)benchmark criteria enabled quality ***:A total of 250 PAA questions were ***‐oriented PAA questions describing what to expect during and after the surgery on topics such as postoperative management,risks or complications of surgery,and technical details were significantly less popular among the“thyroid surgery”group(P<0.001,P=0.005,and P<0.001,respectively).PAA questions about scarring and hypocalcemia were nearly threefold more popular than those related to pain(335 and 319 vs.113 combined search engine response page count,respectively).The overall JAMA quality score remained low(2.50±1.07),despite an increasing number of patients searching for“thyroidectomy”(r(77)=0.30,P=0.007).Conclusions:Patients searching for the nonspecific term“thyroid surgery”received a curated collection of PAA questions that were significantly less likely to educate them on what to expect during and after surgery,as compared to patients with higher health literacy who search with the term“thyroidectomy.”This suggests that the content of PAA questions differs based on the presumed health literacy of the internet user.

关键词： information quality online health education search analytics thyroid surgery thyroidectomy