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Beta-lactam antibiotic resistance among Escherichia coli isolates from patients with urinary tract infections in Vietnam:A systematic review and meta-analysis

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Asian Pacific Journal of tropical Medicine 2024年第6期17卷 243-255,I0001-I0003页

作者： Dat t Nguyen Princess Margaret Cancer Centre University Health NetworkTorontoOntarioCanada

Objective:to investigate the evolving patterns of antimicrobial resistance against beta-lactam antibiotics in Escherichia coli isolates from urinary tract infection patients in Vietnam,covering the period from 2005 to ***:29 Descriptive studies published between 2010 and 2022 in English and Vietnamese were included in the *** on resistance rates to beta-lactam antibiotics,including cephalosporins and carbapenems,were extracted and *** pooled resistance rates were calculated using random-effects *** trends in resistance were assessed using linear regression ***:Among the beta-lactam antibiotics studied,Escherichia coli exhibited varying levels of resistance,with cephalosporins showing higher resistance rates compared to *** pooled resistance rates were 66%for cefotaxime,65%for ceftriaxone,54%for ceftazidime,and 56%for *** contrast,carbapenems demonstrated lower resistance rates,with weighted pooled resistance rates ranging from 3%to 4%for meropenem,ertapenem,and *** rates were also observed for amoxicillin/clavulanate(35%),ticarcillin/clavulanate(26%),and piperacillin/tazobactam(12%).Significant annual increases in resistance were noted for imipenem(0.56%,Pthis study highlights the critical issue of antimicrobial resistance in urinary tract infections in Vietnam and emphasizes the importance of prudent antibiotic use and the regular monitoring of resistance *** insights are useful for guiding healthcare professionals in optimizing treatment strategies and for policymakers in formulating evidence-based clinical guidelines to combat antibiotic resistance effectively.

关键词： Antimicrobial resistance Urinary tract infection Vietnam

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Physics prospects at J-PARC

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Chinese Physics C 2010年第9期34卷 1259-1262页

作者： t.Nagae Kyoto University Department of Physics

We have held an inauguration ceremony of the Japan Proton Accelerator Research Complex （JPARC） on July 6,2009,celebrating the completion of its ***,the beam commissioning of the 50 GeV main proton synchrotron is in progress to improve the beam intensity and quality.A lot of important experimental programs in Nuclear Physics are waiting for the *** this report,I introduce some examples.

关键词： hypernuclei J-PARC hadron kaon

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Recent results from HERA

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Chinese Physics C 2010年第9期34卷 1254-1258页

作者： t.Haas Deutsches Elektronensynchrotron

After the end of data taking in 2007,the experiments H1 and ZEUS have entered into an intense phase of data *** results of this effort on neutral （NC） and charged current （CC） cross sections at high Q 2,the longitudinal structure function F L,inclusive diffraction,heavy flavour production and on searches for glueballs are *** shown are results of a combined analysis on inclusive NC and CC cross sections performed by H1 and ZEUS using HERA-I data.

关键词： lepton-proton scattering structure functions QCD glueballs

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Epigenetic marks in zebrafish sperm： insights into chromatin compaction, maintenance of pluripotency, and the role of the paternal genome after fertilization

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Asian Journal of Andrology 2011年第4期13卷 620-621页

作者： Douglas t Carrell Andrology and IVF Laboratories Departments of Surgery （Urology） Obstetrics and Gynecology and Physiology University of Utah School of Medicine Salt Lake City UT 84108 USA

Human sperm chromatin, and the sperm of most mammals, undergoes extensive remodeling during spermiogenesis during which 85%-95% of the histones are removed and replaced with protamines. the replacement of most histones with protamines facilitates a tighter packaging of the chromatin that is necessary for normal sperm function, and may help protect sperm DNA from damage during transport.

关键词： Epigenetic fertilization

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Numerical simulation of triaxial compression test for brittle rock sample using a modified constitutive law considering degradation and dilation behavior

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Journal of Central South University 2015年第8期22卷 3097-3107页

作者：谭鑫 KONIEtZKY H FRüHWIRt t College of Civil Engineering Hunan University Geotechnical Institute TU Bergakademie Freiberg

the understanding of the rock deformation and failure process and the development of appropriate constitutive models are the basis for solving problems in rock engineering. In order to investigate progressive failure behavior in brittle rocks, a modified constitutive model was developed which follows the principles of the continuum damage mechanics method. It incorporates non-linear Hoek-Brown failure criterion, confining pressure-dependent strength degradation and volume dilation laws, and is able to represent the nonlinear degradation and dilation behaviors of brittle rocks in the post-failure region. A series of triaxial compression tests were carried out on Eibenstock(Germany) granite samples. Based on a lab data fitting procedure, a consistent parameter set for the modified constitutive model was deduced and implemented into the numerical code FLAC3 D. the good agreement between numerical and laboratory results indicates that the modified constitutive law is well suited to represent the nonlinear mechanical behavior of brittle rock especially in the post-failure region.

关键词： progress failure strength degradation dilation Hoek-Brown criterion numerical simulation brittle rock

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Pt／Au Schottky Contacts to Modulation—Doped AlxGa1—xN／GaN Heterostructures Using Pre—deposition Surface treatment

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Chinese Physics Letters 2002年第12期19卷 1853-1855页

作者：刘杰 t.Someya 等 NationalLaboratoryofSolidStateMicrostructuresandDepartmentofPhysics NanjingUniversityNanjing210093 ResearchCenterforAdvancedScienceandtechnologyandInstituteofIndustrialScience

Pt/Au Schottky contacts were fabricated on modulation-doped Al0.22GaN0.78/GaN heterostructures. Some different pre-deposition surface treatments were used to prevent the formation of the native oxide layer on the Al0.22GaN0.78 surface. X-ray photoelectron spectroscopy measurements indicate that the pre-deposition surface treatment with boiling (NH4)2S solution can remove the native oxide layer on the Al0.22Ga0.78N surface effectively. the highest Schottky barrier height of 1.13eV was obtained on the (NH4)2S-treated Al0.22GaN0.78/GaN heterostructure.

关键词： Modulation

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A comparison of genetic risk score with family history for estimating prostate cancer risk

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Asian Journal of Andrology 2016年第4期18卷 515-519页

作者： Brian t Helfand Division of Urology NorthShore University HealthSystem University of Chicago Pritzker School of Medicine 2650 Ridge Avenue Evanston IL 60201 USA.

Prostate cancer （PCa） testing is recommended by most authoritative groups for high-risk men including those with a family history of the disease. However, family history information is often limited by patient knowledge and clinician intake, and thus, many men are incorrectly assigned to different risk groups. Alternate methods to assess PCa risk are required. In this review, we discuss how genetic variants, referred to as PCa-risk single-nucleotide polymorphisms, can be used to calculate a genetic risk score （GRS）. GRS assigns a relatively unique value to all men based on the number of PCa-risk SNPs that an individual carries. this GRS value can provide a more precise estimate of a man＇s PCa risk. this is particularly relevant in situations when an individual is unaware of his family history. In addition, GRS has utility and can provide a more precise estimate of risk even among men with a positive family history. It can even distinguish risk among relatives with the same degree of family relationships. taken together, this review serves to provide support for the clinical utility of GRS as an independent test to provide supplemental information to family history. As such, GRS can serve as a platform to help guide-shared decision-making processes regarding the timing and frequency of PCa testing and biopsies.

关键词： family history genetic risk score prostate cancer single-nucleotide polymorphisms

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Prostate cancer cells metastasize to the hematopoietic stem cell niche in bone

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Asian Journal of Andrology 2011年第4期13卷 622-623页

作者： Evan t Keller Departments of UroJogy and Pathology University of Michigan Ann Arbor MI 48109 USA

the majority of men with advanced prostate cancer develop bone metastases as opposed to metastases at other sites. It has been unclear why prostate cancer selectively metastasizes to and proliferates in bone. Recently, Shiozawa et al. delineated a mechanism that may account for the establishment of prostate cancer in bone. Specifically, they identified that prostate cancer cells compete with hematopoietic stem cells （HSC） for the osteoblast in the HSC niche of the bone. Defining the mechanisms through which prostate cancer cells establish themselves in bone is critical towards developing effective therapeutic strategies to prevent or target bone metastases.

关键词： Prostate hematopoietic

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Poroelastodynamic responses and elastic moduli of a transversely isotropic porous cylinder under forced deformation test

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International Journal of Mining Science and technology 2023年第7期33卷 793-800页

作者： Chao Liu Dung t.Phan Aramco Research Center-Houston Houston TX 77084USA

Existing transversely isotropic poroelastodynamics solutions are limited to infinite domains and without experimental validation. Furthermore, there is a lack of analytical simulations for the elastic moduli dispersion of fluid-saturated porous cylinders. to address these three limitations and investigate the mechanisms of moduli dispersion, we present the analytical solutions of the poromechanical responses and the elastic moduli dispersion of a transversely isotropic, fluid-saturated, finite porous cylinder subjected to a forced deformation test. through an example, we demonstrate the effects of loading frequency, boundary conditions, and material's anisotropy, dimension, and permeability on the responses of pore pressure,force, displacement, and dynamic elastic moduli of the cylinder. the specimen's responses are significantly influenced by the frequency of the applied load, resulting in a drained state at low frequencies and an undrained state at high frequencies. At high frequencies, the sample behaves identically for an open or a closed lateral boundary, and permeability has insignificant effects. the dynamic elastic moduli are mainly controlled by the loading frequency and the ratio of the sample's radius to its height. Lastly,we show excellent matches between the newly derived analytical solution and laboratory measurements on one clay and two shale samples from Mont terri.

关键词： Poroelastodynamics Dynamic moduli transversely isotropic Porous cylinder Forced deformation test

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Aphrodisiac potentials of the aqueous extract of Fadogia agrestis(*** Hiern) stem in male albino rats

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Asian Journal of Andrology 2005年第4期7卷 399-404,页

作者： M.t.Yakubu M.A.Akanji A.t.Oladiji Medicinal Plants Research Laboratory Department of BiochemistryUniversity of IlorinPMB 1515IlorinNigeria

Aim： to evaluate the phytochemical constituents and the agrestis （Rubiaceae） stem in male albino rats. Methods： aphrodisiac potential of the aqueous extract of Fadogia the aqueous stem extract of the plant was screened for phytochemical constituents. Male rats were orally dosed with 18 mg/kg, 50 mg/kg and 100 mg/kg body weight, respectively, of the extract at 24 h intervals and their sexual behavior parameters and serum testosterone concentration were evaluated at days 1, 3 and 5. Results： Phytochemical screening revealed the presence of alkaloids and saponins while anthraquinones and flavonoids are weakly present. All the doses resulted in significant increase in mount frequency, intromission frequency and significantly prolonged the ejaculatory latency （P 〈 0.05） and reduced mount and intromission latency （P 〈 0.05）. there was also a significant increase in serum testosterone concentrations in all the groups in a manner suggestive of dose-dependence （P 〈 0.05）. Conclusion： the aqueous extract of Fadogia agrestis stem increased the blood testosterone concentrations and this may be the mechanism responsible for its aphrodisiac effects and various masculine behaviors. It may be used to modify impaired sexual functions in animals, especially those arising from hypotestosteronemia.

关键词： Fadogia agrestis aphrodisiacs sexual behavior testosterone erectile dysfunction

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