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非增强血流抑制技术MR成像检测腔内动脉瘤修复术后内漏并发症:与增强Ct对比的可行性研究

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国际医学放射学杂志 2017年第2期 233-233页

作者： K.Mori t.saida F.Sato Y.Uchikawa t.Konishi t.Ishiguro 赵蕾 Department of Radiology Faculty of Medicine University of Tsukuba

摘要目的评价MR非增强运动敏感稳态(MSDE)准备平衡快速梯度回波(BtFE)序列用于腔内动脉瘤修复术(EVAR)后内漏检测的可行性。方法对46例主动脉和/或髂

关键词：修复术腔内动脉瘤血流抑制技术 MR 内漏 Ct

子宫动脉栓塞术前评估子宫、卵巢动脉:非增强磁共振血管成像的优势

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国际医学放射学杂志 2010年第4期 373-373页

作者： K.Mori t.saida Y.Shibuya N.takahashi M.Shiigai K.Osada 高飞 Department of Radiology Institute of Clinical MedicineUniversity of TsukubaTennodai 1-1-1TsukubaIbaraki 305-8575Japan

目的阐明非增强磁共振血管成像(MRA)在子宫动脉栓塞术(UAE)中的优势。材料与方法此回顾性研究经伦理委员会通过,无需知情同意书。55例妇女(26～52岁,平均年龄42岁)因有症

关键词：卵巢动脉 MRA 磁共振血管成像子宫女生殖器动脉栓塞

Using the Markov Chain for the Generation of Monthly Rainfall Series in a Semi-Arid Zone

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Open Journal of Modern Hydrology 2016年第2期6卷 51-65页

作者： Mouelhi Safouane Nemri saida Jebari Sihem Slimani Mohamed Laboratoire Hydrologie-CES Ariana Tunisie Institut National de Recherches en Génie Rural Eaux et Forêt (INRGREF) Ariana Tunisie Laboratoire des Sciences et techniques de l’Eau Institut National Agronomique de Tunisie Tunis-Mahrajène Tunisie

Numerous methodologies have been developed in the literature for the generation of rain. However, in semi-arid areas where the irregularity of rain is contrasted, the question of the applicability of these models is still relevant. the objective of this article is to propose a development method of stochastic generator of monthly rainfall series. the present work is based on the modeling of the occurrence and the quantity of rain in a separate way. the occurrence is treated in two stages. the first step considers the Markov chain according to the occurrence of annual statements (dry, average and wet). the second step uses the monthly rankings. the amount of rain is calculated based on historical series according to the monthly rank and the annual statement noted. this method is applied to rainfall data recorded at five rainfall stations in semi-arid region of Central tunisia. the usual and conventional statistical tests of the generated series have shown the validity of this method.

关键词： Stochastic Generation Rainfall Series Markov Chain Semiarid Central tunisia

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养殖废水固定化微生物脱氮技术研究进展

海洋科学 2004年第4期28卷 66-69页

作者：任海波汝少国赵书云 Haruo saida 中国海洋大学海洋生命学院山东青岛266003 toyama University of International Studies

20世纪80年代以来,中国在海水养殖业持续高速发展的同时,由于环境保护措施的滞后,致使养殖水域的水体富营养化现象日趋严重,从而导致了沿岸海域生态系统的退化、赤潮和大规模病害的频繁发生[1].富营养化养殖海域最为突出的问题是氮、磷... 详细信息

20世纪80年代以来,中国在海水养殖业持续高速发展的同时,由于环境保护措施的滞后,致使养殖水域的水体富营养化现象日趋严重,从而导致了沿岸海域生态系统的退化、赤潮和大规模病害的频繁发生[1].富营养化养殖海域最为突出的问题是氮、磷含量严重超标.国家环境保护"十五"计划指出,"十五"期间氨氮排放总量要控制在165万t以内,这就意味着今后中国的污水处理包括养殖废水处理必须进行脱氮.……

关键词：养殖废水固定化微生物技术生物脱氮环境保护

Photoluminescence Compounds ZnGa2Se4and ZnGa2Se4: Eu2+

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Journal of Modern Physics 2012年第8期3卷 827-830页

作者： Oktay tagiyev saida Asadullayeva Gurban Eyyubov Ulvi Kasumov Kenan tagiyev Institute of Chemistry Azerbaijan NAS AZ 1143 33 H. Javid ave. Baku Azerbaijan Institute of Physics of Azerbaijan NAS AZ-1143 33 H. Javid ave. Baku Azerbaijan

Photoluminescence (PL) spectra measurements have been carried out in the ternary chalcopyrite semiconductor compounds ZnGa2Se42Se4: Eu2+ using single-wavelength excitation of a Hg lamp with λ = 365 and 375 nm. Measurements were performed at the temperature range of (120 ~ 220 K) and (110 ~ 230 K) for ZnGa2Se4 and ZnGa2Se4:Eu2+, respectively. No PL was observed for both crystals at the temperatures higher than 220 K (ZnGa2Se4) and 230 K (ZnGa2Se4:Eu2+). At temperatures lower than ~220 K and ~230 K one and three lines were observed for ZnGa2Se4 and ZnGa2Se4: Eu at 591 nm and 566, 591, 646 nm, respectively. 566 nm line was assigned as due of the 4f65d→ 4f7 (8S7/2) transition of Eu2+ ions, whereas the rest two lines were attributed to the donor-acceptor recombination pairs. Probability of non-radiation transfers (A = 108 ~109 s-1), energy of optical phonons (hω= 25 ~ 30 meV), Huan Rice parameter (S = 8 ~ 10), energy of thermal quenching (△E = 0.02 ~ 0.06 eV) were determined from the tem-perature dependences of the full width at half maximum (FWHM = Г(t)).

关键词： ternary Chalcopyrite Photoluminescence Rare-Earth Elements

早期肢端原位黑素瘤:皮肤镜下平行皮纹模式和显微镜下特征的关系

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世界核心医学期刊文摘（皮肤病学分册） 2006年第12期2卷 41-42页

作者： Ishihara Y. saida t. Miyazaki A. 朱国兴 Department of Dermatology Shinshu University School of Medicine 3-1-1Asahi Matsumoto 390-8621 Japan Dr.

In non-white populations, acral skin is the most prevalent site of malignant melanoma. Early melanomas of this anatomic site are often misdiagnosed as melanocytic nevi, which are not uncommon on acral skin. In fact, clinical and/or histopathological features of melanocytic nevi occasionally mimic those of early acral melanoma and vice versa, and thus differentiation of early acral melanoma from melanocytic nevus is sometimes very difficult for clinicians as well as for histopathologists. Our dermoscopic investigation has revealed that the parallel ridge pattern, a band-like pigmentation on the ridges of the skin markings, is highly specific to malignant melanoma in situ on acral volar skin. In the present study, we reviewed 22 acral melanocytic lesions that showed the parallel ridge pattern on dermoscopy but had very subtle clinical and/or histopathological presentations. We diagnosed 20 of them as early melanoma in situ by careful histopathological examination,which revealed histopathological features very similar to those seen in macular portions of overt acral melanoma, but fundamentally different from features found in melanocytic nevi on acral skin. In correspondence with their dermoscopic pattern, in these early lesions of acral melanomas, proliferation of solitary arranged melanocytes was mainly detected in the crista profunda intermedia, the epidermal rete ridge underlying the ridge of the skin marking. the two remaining lesions were diagnosed as possible cases of acquired melanocytic nevus because of the formation of well-demarcated nests of melanocytes in the epidermal rete ridges. We propose that a finding of preferential proliferation of solitary arranged melanocytes in the crista profunda intermedia is an important clue for the histopathological diagnosis of early phases of acral melanoma.

关键词：皮肤镜肢端黑素瘤黑素细胞痣皮纹

通过特殊皮肤镜模式和细胞周期蛋白D1基因扩增确定组织病理学未认定的早期肢端原位黑色素瘤皮损

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世界核心医学期刊文摘（皮肤病学分册） 2006年第2期2卷 24-25页

作者： Yamaura M. takata M. Miyazaki A. saida t. 王琼 Department of Dermatology Shinshu University School of Medicine Asahi 3- 1- 1 Matsumoto 390- 8621 JapanDr.

Objective: to define early lesions of acral melanoma in situ that cannot be recognized histopathologically. Design: A retrospective review of the clinical, dermoscopic, and histopathological findings. Setting: University department of dermatology. Patients: thirty- three patients with melanocytic lesions on acral volar skin that were clinically suspected of being early melanomas. Main Outcome Measures: Fluorescent in situ hybridization studies to detect the cyclin D1 gene ampli- fication in proliferating melanocytes, which is a characteristic genetic aberration recently found in acral melanoma. Results: Seventeen of 33 lesions were histopathologically diagnosed as either melanoma in situ (8 lesions) or benign melanocytic nevi (9 lesions). Amplification of the cyclin D1 gene was observed in 2 (25% ) of the 8 melanomas in situ. None of the 9 nevi showed the amplification. the remaining 16 lesions were, however, difficult to classify histopathologically because most of them showed only a slight increase of nonatypical melanocytes in the basal cell layer of the epidermis. On dermoscopic examination, 9 of these 16 lesions exhibited the parallel ridge pattern that has been reported to be highly specific to melanoma in situ, and 4 (44% ) of them had amplifications of the cyclin D1 gene. Amplifications were not found in any of the remaining 7 lesions that showed dermoscopic patterns suggestive of melanocytic nevi. Conclusions: Cyclin D1 gene amplification detected by fluorescent in situ hybridization identified a very early progression phase of acral melanoma that precedes histopathologically defined melanoma in situ. the present study also indicates the specificity of the parallel ridge pattern on dermoscopy to detect melanomas on acral volar skin at such a very early developmental phase.

关键词：黑色素瘤细胞周期蛋白基因扩增组织病理学肢端病理学诊断掌跖基底细胞层病理学确诊临床拟

Exploration and Mapping of Metalliferous Black Shales in the Saghro temporary Subsidence Zones (Anti-Atlas, Morocco)

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Open Journal of Geology 2023年第7期13卷 740-762页

作者： Ali Bouayachi saida Alikouss Zouhir Baroudi Youssef Zerhouni Lahcen Rakhis Mohammed Zouhair Assia Idrissi Mourad Essalhi Barzouk Abdelhafed Department of Geology Faculty of Sciences Ben M’Sik University Hassan II Casablanca Morocco MANAGEM Group 191 bd Med Zerktouni Twin Center Tour A. 20100 Casablanca Morocco Department of Geology Faculty of Sciences University Mohamed V Rabat Morocco Faculty of Sciences and techniques University Molay Ismail Errachidia Morocco Faculty of Sciences Semlalia Caddi Ayyad University Marrakech Morocco

the Saghro massif constitutes a vast metallogenic province with numerous deposits and shows of base metals (lead, zinc, copper) and precious metals (gold and silver), besides various useful substances (talc, pyrophyllite, barite, fluorite). Silver/lead occurrences are concentrated along the Cryogenian Imiter series and moderately at Boumalne and Sidi Flah. Copper occupies the plutonic intrusions and intrusive rocks of the East-Central Saghro while barite deposits are widespread throughout the Cambrian cover of the East Saghro in contact with the Ediacaran basement. to justify this distribution, the new contributions of the cartography and the organic geochemistry of the black shales of Jbel Saghro have clearly shown the particularity of the Imiter black shales in terms of the richness in organic matter (tOC = 0.18%), the blackish color and the friability. the Boumalne and Sidi Flah groups present some similarities with the Imiter group, such as the sub-equatorial structuring, the friable pelites and the richness in organic matter (Boumalne tOC = 0.11% and SidiFlah tOC = 0.16%), which is a quite good show that requires to reinforce the exploration works. For Western Saghro in the Iknioun and Qalaa’t M’Gouna groups, the variations in the thickness of the volcanic cover show an irregular paleotopography with hard, greenish, organic-poor pelitic sediments (tOC = 0.01 to 0.04%). We can conclude that the formation of Imiter-type silver concentrations requires the combination of the sedimentological, the volcanic and structural factors. For Imiter-type silver these factors are: a fine pelitic and argillic casing deposited in a confined environment, a basic volcanism source of metals and other intermediate to acid generated by the hydrothermalism and heat, a convenable paleotopography and a network of fracturations to trap the mineralizations.

关键词： Saghro Metallic Shales Silver tOC Exploration Cryogenic Polymetallic Imiter

HCV/HBV复合抗原基因的克隆、表达及免疫应答研究

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中国生物化学与分子生物学报 1999年第6期15卷 881-884页

作者：黄建生许谆 saida.SALEH 解咏梅张明徽任大明第一军医大学广州51051 复旦大学遗传学研究所遗传工程国家重点实验室上海200433 第二军医大学免疫学教研室上海200433

为探讨ＨＣＶ／ＨＢＶ复合疫苗的可行性，将合成的丙型肝炎病毒（ＨＣＶ）复合多表位抗原基因ＰＣＸ与ＨＢｓＡｇ基因连接成ＰＣＸＳ基因，与β－半乳糖苷酶（ＧＺ）基因融合后在大肠杆菌及减毒鼠伤寒沙门氏菌中获得表达．目的蛋白Ｇ... 详细信息

为探讨ＨＣＶ／ＨＢＶ复合疫苗的可行性，将合成的丙型肝炎病毒（ＨＣＶ）复合多表位抗原基因ＰＣＸ与ＨＢｓＡｇ基因连接成ＰＣＸＳ基因，与β－半乳糖苷酶（ＧＺ）基因融合后在大肠杆菌及减毒鼠伤寒沙门氏菌中获得表达．目的蛋白ＧＺ－ＰＣＸＳ可被抗－ＨＢｓ及抗－ＨＣＶ抗体所特异识别．ＧＺ－ＰＣＸＳ抗原皮下注射免疫ＩＣＲ小鼠后，诱发了较高水平的抗－ＧＺ－ＰＣＸＳＩｇＧ反应．构建的重组减毒鼠伤寒沙门氏菌ＳＬ３２６１（ｐＷＲ／ＰＣＸＳ）口服免疫小鼠后，诱发了高水平的ＣＤ８＋Ｔ细胞增殖反应及抗ＧＺ－ＰＣＸＳＩｇＧ反应．所有免疫小鼠均未见明显的毒副作用．该研究揭示，ＨＣＶ／ＨＢＶ复合抗原可诱发特异性体液免疫及细胞免疫应答，而活菌苗口服可能是理想的免疫途径，为ＨＣＶ／ＨＢＶ双价疫苗研究提供了一定的理论及实验依据．

关键词：免疫应答口服法双价疫苗 HCV HBV 基因克隆