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An AMR capable Finite element Diffusion Solver for ALe Hydrocodes

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Plasma Science and technology 2015年第2期17卷 109-116页

作者： A.c.FISHeR D.S.BAILeY t.B.KAISeR D.c.eDeR B.t.N.GUNNeY N.D.MASteRS A.e.KONIGeS R.W.ANDeRSON Lawrence Livermore National Laboratory Lawrence Berkeley National Laboratory

We present a novel method for the solution of the diffusion equation on a composite AMR mesh. this approach is suitable for including diffusion based physics modules to hydrocodes that support ALe and AMR capabilities. to illustrate, we proffer our implementations of diffu- sion based radiation transport and heat conduction in a hydrocode called ALe-AMR. Numerical experiments conducted with the diffusion solver and associated physics packages yield 2nd order convergence in the L2 norm.

关键词： hydrodynamic simulation heat conduction thermal radiation adaptive meshrefinement finite element method

Recalescence Behavior, Solidification characteristics and Microstructure transformation of Rapidly Solidified Undercooled cu-based Alloys

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Journal of Wuhan University of technology(Materials Science) 2022年第6期37卷 1228-1239页

作者： WANG Hongfu tANG cheng He Xibin YANG Jin’e XIe Jinpeng School of Mechanical engineering North University of ChinaTaiyuan 030051China Jiangsu Yingchuang Power technology co. LtdSuzhou 215000China

the undercooled solidification microstructures of cu55Ni45,cu55Ni43co2,and cu60Ni38co2 cu-base alloys were obtained by fluxing *** infrared temperature measuring device,the law of the change of the recalescence degree with the increase of the undercooling during rapid solidification was *** the same time,high-speed camera was used to capture and photograph the images of solid/liquid interface migration during rapid solidification of undercooled melt,and the morphology evolution of solidification front was ***,the microstructure morphology and transformation process of the cubased alloys were systematically *** is found that the microstructure morphology of the alloys goes through the same evolution process and appeared two grain refinement phenomena,that is,“coarse dendrite-equiaxed grain-oriented fine dendrite-equiaxed grain”.But its characteristics undercoolingΔt_(1),Δt_(2),and critical undercoolingΔt^(*)*** backscatter diffraction(eBSD)and transmission electron microscopy(teM)were used to characterize the grain refinement structure with high *** results show that the grain refinement structure with high undercooling presents a very high proportion of high angle grain boundaries,the grain orientation is random and there is no high strength texture,and a large number of annealing twins,which indicates that recrystallization occurs in the *** results show that dislocation network and stacking fault density are relatively low in most areas of grain refinement structure with high undercooling,which can confirm the theory that stress induces recrystallization of the structure.

关键词： rapid solidification recalescence degree solidification front microstructure

Stochastic framework for modeling the linear apparent behavior of complex materials:Application to random porous materials with interphases

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Acta Mechanica Sinica 2013年第6期29卷 773-782页

作者： J.Guilleminot t.t.Le c.Soize Universit Paris-est Laboratoire Modlisation et Simulation Multi EchelleMSME UMR8208 CNRS5 Bd Descartes77454 Marne la ValleFrance

this paper is concerned with the modeling of randomness in multiscale analysis of heterogeneous materials. More specifically, a framework dedicated to the stochastic modeling of random properties is first introduced. A probabilistic model for matrix-valued second-order random fields with symmetry propertries, recently proposed in the literature, is further reviewed. Algorithms adapted to the Monte carlo simulation of the proposed representation are also provided. the derivations and calibration procedure are finally exemplified through the modeling of the apparent properties associated with an elastic porous microstructure containing stochastic interphases.

关键词： Apparent properties Maxent Probabilistic model

Reduced Shell Model calculations of ^111Sb and ^112Sb

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chinese Physics Letters 2007年第6期24卷 1521-1524页

作者： e. Dikmen t, Akyǖrek Department of Physics Sǖleyman Demirel University Isparta Turkey

the low-lying states of the mid-heavy odd-even ^111Sb and odd-odd ^112Sb isotopes are calculated for the first time within the shell model framework. the shell model calculations have been carried out within the reduced model space including the single particle orbits ld5/2,097/2, ld3/2, 2Sl/2. We obtain the energy spectra for the ^111Sb and ^112Sb isotopes in the reduced model space by using cD-Bonn two-body effective nucleon-nucleon interaction. the energy spectra are compared to the experimental results to give some discussion about the low-lying states of ^111Sb and ^112Sb.

关键词： calculations Reduced Model

equivalent series system to model a multiple friction pendulum system with numerous sliding interfaces for seismic analyses

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earthquake engineering and engineering Vibration 2014年第1期13卷 85-99页

作者： c.S.tsai H.c.Su t.c.chiang Department of civil engineering Feng Chia University Department of Water Resources engineering and conservation Feng Chia University earthquake Proof Systems Inc.

current structural analysis software programs offer few if any applicable device-specifi c hysteresis rules or nonlinear elements to simulate the precise mechanical behavior of a multiple friction pendulum system(MFPS) with numerous sliding *** on the concept of subsystems,an equivalent series system that adopts existing nonlinear elements with parameters systematically calculated and mathematically proven through rigorous derivations is *** aim is to simulate the characteristics of sliding motions for an MFPS isolation system with numerous concave sliding interfaces without prior knowledge of detailed information on the mobilized forces at various sliding *** MFPS with numerous concave sliding interfaces and one articulated or rigid slider located between these interfaces is divided into two subsystems: the fi rst represents the concave sliding interfaces above the slider,and the second represents those below the *** equivalent series system for the entire system is then obtained by connecting those for each subsystem in *** equivalent series system is validated by comparing numerical results for an MFPS with four sliding interfaces obtained from the proposed method with those from a previous study by Fenz and ***,these numerical results demonstrate that an MFPS isolator with numerous concave sliding interfaces,which may have any number of sliding interfaces,is a good isolation device to protect structures from earthquake damage through appropriate designs with controllable mechanisms.

关键词： seismic isolation base isolation earthquake engineering multiple friction pendulum system structural control mathematical modeling equivalent series system

Precision bending of high-quality components for volume applications

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transactions of Nonferrous Metals Society of china 2010年第11期20卷 2100-2110页

作者： t.WeLO F.WIDeRe Department of engineering Design and Materials Norwegian University of Science and Technology(NTNU)

Recent new technology developments were presented in the field of industrial bending operations,including flexible stretch forming and 3D rotary stretch *** were made to give an overview of different mechanisms that influence dimensional accuracy,including local cross-sectional deformations such as suck-in and volume conservation effects,along with global deformations such as *** analytical model was developed to determine the particular influence of different material,geometry and process parameters on dimensional variability of bent *** results were discussed in terms of overall process capability(cp) and associated process *** results show that different governing mechanisms prevail in various bending operations,meaning that attention has to be placed on controlling those process parameters that really are important to part quality in each specific *** strategies may be defined for reducing *** alternative may be to design more robust process and tool technology that reduce the effect of upstream parameters on dimensional variability of the formed *** results show that optimal tool design and technology may in specific cases improve the dimensional accuracy of a formed *** on the findings discussed herein,it is concluded that advances in industrial bending operations require focus on improving the understanding of mechanical mechanisms,including models and parameter development,new technology developments,including process,tool,measurement and control capabilities,and process discipline at the shop floor,combined with a basic philosophy of controlling process parameters rather than part attributes.

关键词： bending technology tools dimensional accuracy distortions springback formability

t lymphocytes and aortic aneurysms

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Science china(Life Sciences) 2014年第8期57卷 795-801页

作者： LV Bing-Jie LI JingYong cheng Xiang Laboratory of cardiovascular Immunology Institute of CardiologyUnion HospitalTongji Medical CollegeHuazhong University of Science and Technology Laboratory of Biological targeted therapy of Ministry of education

Aortic aneurysms are common and life threatening problems with high rates of *** initiation and progression of aneurysms are characterized by extensive extracellular matrix degradation and immune cells invasion within arterial *** the pathogenesis of all aneurysms,inflammation and immune cells play a significant *** t cells are abundant in aneurysm tissue,their functions in initiation and propagation of aneurysms remain *** review summarizes the current state of knowledge of t lymphocytes on this disease and focuses on potential mechanisms of specific t cell responses.

关键词： t cells cytokines aortic aneurysms inflammation pathogenesis

A facile,branched DNA assay to quantitatively measure glucocorticoid receptor auto-regulation in t-cell acute lymphoblastic leukemia

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chinese Journal of cancer 2012年第8期31卷 381-391页

作者： Jason R.Schwartz Purvaba J.Sarvaiya Lily e.Leiva Maria c.Velez tammuella c.Singleton Lolie c.Yu Wayne V.Vedeckis Department of Biochemistry and Molecular Biology Stanley S.Scott cancer center Department of Pediatrics Louisiana State University Health Science CenterNew OrleansLA 70112USA Department of Pediatric Hematology/Oncology Children's HospitalNew OrleansLA 70112USA

Glucocorticoid(Gc) steroid hormones are used to treat acute lymphoblastic leukemia(ALL) because of their pro-apoptotic effects in hematopoietic ***,not all leukemia cells are sensitive to Gc,and no assay to stratify patients is *** the Gc-sensitive t-cell ALL cell line ceM-c7,auto-up-regulation of RNA transcripts for the glucocorticoid receptor(GR) correlates with increased apoptotic *** study aimed to determine if a facile assay of GR transcript levels might be promising for stratifying ALL patients into hormone-sensitive and hormone-resistant *** GR transcript profiles of various lymphoid cell lines and 4 bone marrow samples from patients with t-cell ALL were analyzed using both an optimized branched DNA(bDNA) assay and a real-time quantitative reverse transcription-polymerase chain reaction *** were significant correlations between both assay platforms when measuring total GR(exon 5/6) transcripts in various cell lines and patient samples,but not for a probe set that detects a specific,low abundance GR transcript(exon 1A3).Our results suggest that the bDNA platform is reproducible and precise when measuring total GR transcripts and,with further development,may ultimately offer a simple clinical assay to aid in the prediction of Gc-sensitivity in ALL patients.

关键词：糖皮质激素受体淋巴细胞白血病 DNA检测自动调节定量测量 t细胞支链急性

Restoring homeostasis of cD4^+ t cells in hepatitis-B-virusrelated liver fibrosis

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World Journal of Gastroenterology 2015年第38期21卷 10721-10731页

作者： Li-Sha cheng Yun Liu Wei Jiang Department of Gastro-enterology Zhongshan HospitalFudan University

Immune-mediated liver injury is widely seen during hepatitis B virus(HBV) infection. Unsuccessful immune clearance of HBV results in chronic hepatitis and increases the risk of liver cirrhosis and hepatocellular carcinoma. HBV-related liver fibrosis(HBVLF),occurring as a result of HBV-induced chronic hepatitis,is a reversible,intermediate stage of chronic hepatitis B(cHB) and liver cirrhosis. therefore,defining the pathogenesis of HBVLF is of practical significance for achieving better clinical outcomes. Recently,the homeostasis of cD4+ t cells was considered to be pivotal in the process of HBVLF. to better uncover the underlying mechanisms,in this review,we systematically retrospect the impacts of different cD4+t-cell subsets on cHB and HBVLF. We emphasize cD4+ t-cell homeostasis and the important balance between regulatory t(treg) and t helper 17(th17) cells. We discuss some cytokines associated with treg and th17 cells such as interleukin(IL)-17,IL-22,IL-21,IL-23,IL-10,IL-35 and IL-33,as well as surface molecules such as programmed cell death protein 1,cytotoxic t lymphocyte-associated antigen 4,t cell immunoglobulin domain and mucin domain-containing molecule 3 and cannabinoid receptor 2 that have potential therapeutic implications for the homeostasis of cD4+ t cells in cHB and HBVLF.

关键词： Homeostasis Regulatory t cells t helper 17 cells c