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Open Journal of Applied Sciences 2014年第3期4卷 96-102页

作者： Hanan Ali Maram t. H. Abou Kana Mohamed Atta Khedr Department of Laser Sciences and Interactions National Institute of Laser Enhanced Sciences University of Cairo Giza Egypt

Samarium doped Yttrium aluminum garnet (YAG) nanopowders with different concentration (0.5%, 1%, 2%, 3%, 5% and 8% mol) were prepared by simple and low cost co-precipitation method. We found that the precursor begins converting to pure YAG at relatively low temperature around 900°c, and no intermediate phases were detected. the powders annealed at 900°c and 1000°c in air with average particle size around ≈30 nm were characterized by means of X-ray diffraction (XRD) analysis and infrared (IR) spectroscopy. the photoluminescent measurements showed that the reddish-orange (RO) emission transition 4G5/2:6H7/2 is more prominent. In addition, the optimum concentration of doped Sm ions that lead to maximum intensity was reported. Also, fluorescence efficiencies as pumping power dependence for different Sm3+ ions concentrations were explored.

关键词： Sm3+ YAG Nanopowders concentration Dependence Optical Properties ceramics

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热液石油的^(14)c年龄比较

地质地球化学 1996年第4期24卷 60-63页

作者： BerndR.t.Simoneit KeithA.Kvenvolden 张祥忠江汉石油学院74#地质系

为了确定热液石油形成的时间界限．我们已放得了三个不同地区样品的14c年龄，这三个地区是：加利任尼亚湾瓜伊马斯盆地．东北太平洋（埃斯卡诺巴海槽和米德尔裂谷）和东非裂谷（坦噶尼喀地堑）。这些数据确定了碳源的年龄，从而为热液... 详细信息

为了确定热液石油形成的时间界限．我们已放得了三个不同地区样品的14c年龄，这三个地区是：加利任尼亚湾瓜伊马斯盆地．东北太平洋（埃斯卡诺巴海槽和米德尔裂谷）和东非裂谷（坦噶尼喀地堑）。这些数据确定了碳源的年龄，从而为热液石油的形成和定位提供了最大年龄。年龄最小的石油产于瓜伊马斯盆地的南海槽（3200～6600年，平均4692年）；北海村石油的年龄稍大一些（7400年）。年龄较大的石油主要产于埃斯卡诺巴海槽（17000年）和米德尔裂谷（29000年）。东非裂谷的大陆石油样品的年龄为25000年，与东北太平洋的海洋石油样品的年龄相当。这些年龄证实，热液石油的形成是一个非常迅速的过程．是在更新世晚期至现代之间的某段时间内在这些活动的热液体系中进行的。

关键词：油矿床热液成矿碳同位素年龄

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Structure - Antimicrobial Activity Relationship Investigation of Some Butadiene and chalcone Derivatives

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Journal of Life Sciences 2013年第7期7卷 705-711页

作者： Hanoy AL-Amood Hadeel t.AL-Hadithi Ghazwan F. Fadhil Dept. of chemistry College of Science University of Basrah Basrah 61001 Iraq Dept. of Biology College of Science University of Basrah Basrah 61001 lraq Dept. of chemistry Faculty of Science University of Duhok Duhok 1048 BD lraq

the biological activity against Staphylococcus aureus, and Eschericia coil were investigated implementing three series, the first series was l-phenyl-2-（4＇-X-phenyl）-4-（2,4-dichlorophenyl）-1,3-butadiene, where X = H, cH3, OcH3, NH2, c1, F, NO2 and cOOEt; the second was 3,4-dichlorochalcone series namely 3-（3,4-dichlorophenyl）-l-（4＇-X-phenyl）-2-propen-l-one, where X = H, cH3, OcH3, NH2, cI, F, NO2 and cN; and the third one was 2,4-dichlorochalcone series namely 3-（2,4-dichlorophenyl）-l- （4＇-X-phenyl）-2-propen-l-one, where X = H, cH3, OcH3, NH2, c1, F, NO2 and cOOEt. MIc, MBc and the percentage of inhibition （activity） at 20 ~tg/mL, 15 μg/mL and 10μg/mL against Eschericia coli, and at 7.5 lag/mL, 5 μg/mL and 2.5 μg/mL against Staphylococcus aureus, were determined for each compound in the three series. Highest MIc activity against E. coli and S. aureus were given by 2,4-dichlorochalcone series. Butadiene series was similar in behavior to 2,4-dichlorochalcone series in MIc activity against S. aureus. Results of MBc revealed that compounds in the three series exerted high activity against both types of bacteria. compounds substituted with nitro or nitril exhibited higher activity than other compounds in the three series. Percentage of inhibition of halogenated compounds （4＇-c1 and 4＇-F） was almost equal in every series. compounds with substituents （4＇-H and 4＇-cH3） showed fluctuation in activity according to the nature of each series.

关键词： Structure activity relationship chalcone butadiene, Eschericia coli Staphylococcus aureus.

tuning the Structure of Fe-tetracarboxylate Frameworks through Linker-Symmetry Reduction

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ccS chemistry 2021年第2期3卷 1701-1709页

作者： Jiandong Pang christina t.Lollar Sai che Jun-Sheng Qin Jialuo Li Peiyu cai Mingyan Wu Daqiang Yuan Maochun Hong Hong-cai Zhou Department of chemistry Texas A&M UniversityCollege StationTX 77843-3255 State Key Laboratory of Structure chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhouFujian 350002 State Key Laboratory of Inorganic Synthesis and Preparative chemistry College of ChemistryInternational Center of Future ScienceJilin UniversityChangchun 130012 University of chinese Academy of Sciences Beijing 100049

the design and synthesis of stable metal–organic frameworks(MOFs)have been a core obstacle in the widespread application of these functional crystalline porous materials,because of the stability limitations of MOFs under harsh operating ***,a highly stable microporous MOF based on the Fe_(3)O cluster(PcN-678)has been synthesized using a tetracarboxylate *** symmetry reduced tetratopic carboxylate ligand,a mesoporous MOF(PcN-668)could be obtained in which nanoscale cage-like building units and one-dimensional(1D)channels *** neighboring cages were mutual diastereomers in PcN-668 due to the further reduction of the cs symmetry of the free ligand to c1 symmetry after ***,the acid stability of this mesoporous MOF was improved via postsynthetic metal exchange to chromium(PcN-668-cr).the PcN-668-cr exhibited very high stability in both acidic and basic aqueous solutions(pH=1–11).Additionally,the mesoporous MOF showed a high total gravimetric methane uptake(∼500 cm^(3) g^(−1) at 100 bar),while the microporous MOF showed a high volumetric methane storage capacity of 147 cm3 cm−3 at room temperature.

关键词： metal–organic framework mesoporous,highly stable diastereomeric cage methane uptake

AJcN:过敏症来袭怎么办?新型益生菌组合疗法显神效

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现代生物医学进展 2017年第18期17卷 I0003-I0003页

作者： Jennifer c Dennis-Wall tyler culpepper carmelo Nieves Jr. cassie c Rowe Alyssa M Burns carley t Rusch Ashton Federico Maria Ukhanova Sheldon Waugh Volker Mai Mary c christman Bobbi Langkamp-Henken,* Emerging Pathogens Institute University of Florida Gainesville FL and Mcc Statistical consulting LLc Gainesville FL ↵*to whom correspondence should be addressed. E-mail: henken{at}ufl.edu.

当进入过敏季节我们可能并不太会拿出手帕或者打喷嚏来预防过敏。日前，一项刊登在国际杂志the American Journal of clinical Nutrition上的研究报告中。来自佛罗里达大学的研究人员通过研究发现。一种益生菌组合或许能够帮助减轻花粉... 详细信息

当进入过敏季节我们可能并不太会拿出手帕或者打喷嚏来预防过敏。日前，一项刊登在国际杂志the American Journal of clinical Nutrition上的研究报告中。来自佛罗里达大学的研究人员通过研究发现。一种益生菌组合或许能够帮助减轻花粉症的症状。

关键词：防过敏益生菌疗法佛罗里达大学研究人员打喷嚏花粉症

用经验格林函数方法模拟汶川M_W7.9地震的强地震动

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世界地震译丛 2018年第1期49卷 35-52页

作者： c.Xia B.M.Zhao M.Horike t.Kagawa 高楠(译) 王超(译) 朱玉萍(校) 中国地震台网中心中国地震局地球物理研究所不详

汶川M_W7.9地震的发生震惊了中国乃至全世界,不仅仅因为该地震震级巨大,还因为其可怕的伤亡。评估汶川M_W7.9地震的复杂性及破坏力需对其地震特征进行研究。本文运用经验格林函数方法(EGF)模拟了地震的强地震动。首先,选取了4个震级为M_... 详细信息

汶川M_W7.9地震的发生震惊了中国乃至全世界,不仅仅因为该地震震级巨大,还因为其可怕的伤亡。评估汶川M_W7.9地震的复杂性及破坏力需对其地震特征进行研究。本文运用经验格林函数方法(EGF)模拟了地震的强地震动。首先,选取了4个震级为M_W4.9和M_W5.0的余震,对这些余震的运动利用格林函数进行了模拟。通过模拟,可以估算出包括断层规模和应力降在内的余震震源参数。然后,通过试错法正演模拟得出M_W7.9地震凹凸体(强震动生成区)的震源模型。为验证该震源模型的准确性,运用经验格林函数方法模拟合成了9个台站的强地震动。将模拟得出的强地震动与观测记录到的加速度波形、速度波形和拟加速度反应谱相比较。尽管有一些差异,但在大部分台站,合成的强地震动与观测记录结果相吻合。在模拟得出的震源模型中,断层面上3个凹凸体的应力降约为10MPa,而凹凸体面积与破裂面积比为0.24,接近经验关系式得出的结果0.22。

关键词：经验格林函数强地震动加速度反应谱格林函数方法模拟合成震源模型地震震级观测记录

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Proteomics and metabolic phenotyping define principal roles for the aryl hydrocarbon receptor in mouse liver

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Acta Pharmaceutica Sinica B 2021年第12期11卷 3806-3819页

作者： Jian Jin Banrida Wahlang Monika thapa Kimberly Z.Head Josiah E.Hardesty Sudhir Srivastava Michael L.Merchant Shesh N.Rai Russell A.Prough Matthew c.cave Department of Pharmacology&toxicology theUniversity of Louisville School ofMedicineLouisvilleKY 40202USA Department of Endocrinology the Second Affiliated Hospital&Yuying Children’s HospitalWenzhou Medical UniversityWenzhou 325027China Division of Gastroenterology Hepatology&NutritionDepartment of Medicinethe University of Louisville School of MedicineLouisvilleKY 40202USA Superfund Research center the University of LouisvilleLouisvilleKY 40202USA eDepartment of Biochemistry and Molecular Geneticsthe University of Louisville School of MedicineLouisvilleKY 40202USA Department of Bioinformatics and Biostatistics the School of Public Health and Information Sciencesthe University of LouisvilleLouisvilleKY 40202USA centre for Agricultural Bioinformatics ICAR-Indian Agricultural Statistics Research InstituteNew Delhi 110012India the center for Integrative Environmental Health Sciences University of LouisvilleLouisvilleKY 40202USA Division of Nephrology&Hypertension Department of Medicinethe University of Louisville School of MedicineLouisvilleKY 40202USA the Hepatobiology and toxicology center University of LouisvilleLouisvilleKY 40202USA Alcohol Research center University of LouisvilleLouisvilleKY 40202USA Biostatistics and Bioinformatics Facility James Graham Brown Cancer CenterLouisvilleKY 40202USA

Dioxin-like molecules have been associated with endocrine disruption and liver *** better understand aryl hydrocarbon receptor(AHR)biology,metabolic phenotyping and liver proteomics were performed in mice following ligand-activation or whole-body genetic ablation of this *** wild type(Wt)and Ahr^(-/-) mice(taconic)were fed a control diet and exposed to 3,3',4,4',5-pentachlorobiphenyl(PcB126)(61 nmol/kg by gavage)or vehicle for two ***126 increased expression of canonical AHR targets(cyp1 a1 and cyp1 a2)in Wt but not Ahr^(-/-).Knockouts had increased adiposity with decreased glucose tolerance;smaller livers with increased steatosis and perilipin-2;and paradoxically decreased blood ***126 was associated with increased hepatic triglycerides in Ahr^(-/-).the liver proteome was impacted more so by Ahr^(-/-) genotype than ligandactivation,but top gene ontology(GO)processes were *** PcB126-associated liver proteome was *** principally regulated liver metabolism(e.g.,lipids,xenobiotics,organic acids)and bioenergetics,but it also impacted liver endocrine response(e.g.,the insulin receptor)and function,including the production of steroids,hepatokines,and pheromone binding *** effects could have been indirectly mediated by interacting transcription factors or *** biologic roles of the AHR and its ligands warrant more research in liver metabolic health and disease.

关键词： AHR Endocrine disruption Environmental liver disease Nonalcoholic fatty liver disease Perilipin-2 Pheromones PcB126

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通过超声分子成像与二维剪切波弹性成像观察大鼠肝窦毛细血管化以评估肝纤维化

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国际医学放射学杂志 2022年第5期 610-610页

作者： X.Y.Miao t.t.Sha W.Zhang H.c.Zhou c.Qiu H.Deng 陈繁

摘要超声弹性成像是评估肝纤维化严重程度的一线检查方法。然而其应用受限于在早期纤维化检测中的敏感性不足，并且其测量受到炎症的影响。目的评估超声分子成像

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Association of interferon lambda-4 rs12979860 polymorphism with hepatocellular carcinoma in patients with chronic hepatitis c infection

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World Journal of Hepatology 2021年第1期13卷 109-119页

作者： Jóice teixeira de Bitencorte tássia Flores Rech Vagner Ricardo Lunge Deivid cruz dos Santos Mário ReisÁlvares-da-Silva Daniel Simon PPG Biologia celular e Molecular AplicadaàSaúde Universidade Luterana do BrasilCanoas 92425-900Rio Grande do SulBrazil Division of Gastroenterology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-903Rio Grande do SulBrazil

BAcKGROUND Hepatitis c virus(HcV)infection is a public health concern *** factors,including genetic polymorphisms,may be evolved in the progression of HcV infection to liver *** lambdas(IFNLs)modulate the immune response during viral *** induce antiviral activity,interfering in the viral replication by promoting the expression of several genes that regulate immunological *** interferon lambda-4(IFNL4)rs12979860 polymorphism,which is characterized by a c to t transition in intron 1,is associated with spontaneous and treatment-induced clearance of HcV infection and may play a role in the development of HcV-associated liver diseases,including hepatocellular carcinoma(Hcc).AIM to investigate the association of IFNL4 rs12979860 polymorphism with fibrosis,cirrhosis,and Hcc in patients with chronic HcV *** this study was comprised of 305 chronic HcV-infected patients(53 fibrosis,154 cirrhosis,and 98 Hcc cases).the control group was comprised of 260 HcVnegative healthy *** IFNL4 rs12979860 polymorphism was genotyped using the taqMan *** was diagnosed based on liver biopsy findings,while cirrhosis was diagnosed through clinical,laboratory,anatomopathological,and/or imaging *** was diagnosed through imaging tests,tumor,and/or anatomopathological *** the t allele was observed in the three groups of patients(fibrosis,cirrhosis,and Hcc)at a significantly higher frequency when compared with the control group(P=0.047,Pctively).Also,genotype frequencies presented significant differences between the control group and cirrhosis patients(Pcc patients(P=0.002).the risk analysis was performed using the codominant and dominant t allele *** the codominant model,it was observed that the ct genotype showed an increased risk of developing cirrhosis in comparison with the cc genotype[odds ratio(OR)=2.53;95%confidence interval(cI):1.55-4.15;

关键词： Hepatitis c Hepatitis c virus cirrhosis Hepatocellular carcinoma Genetic polymorphism Interferon-lambda