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Studies on the energy transfer system of terbium-norfloxacin chelate and its interaction with serum albumins

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Chinese Journal of Chemistry 1997年第2期15卷 138-143页

作者： Xu, y Shen, HX huang, HG NANKAI UNIV DEPT CHEMTIANJIN 300071PEOPLES R CHINA HEBEI INSt tECHNOL DEPT CHEM ENGNTANGSHAN 063009HEBEIPEOPLES R CHINA

the energy absorbed by norfloxacin could be transferred to terbium(III) through chelation of norfloxacin with terbium(III), then the characteristic fluorescence emission could be observed. the interaction of serum albumins with norfloxacin have been investigated in this paper. the results showed that HSA could inhibit the energy transfer between norfloxacin and terbium(III). But, BSA could not. It was shown that the binding properties of norfloxacin to HSA and BSA were totally different.

关键词： norfloxacin terbium(III) energy transfer HSA BSA

Carbide Formation Process in Directionally Solidified MAR-M247 LC Superalloy

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Journal of Materials Science & technology 1999年第1期15卷 48-52页

作者： Chen, Jian huang, Baiyun Lee, J.H. Choe, S.J. Lee, y.t. Cent S Univ technol Powder Met Res Inst Changsha 410083 Peoples R China Changwon Natl Univ Dept Met & Mat Sci Changwon 641773 South Korea Korea Inst Machinery & Mat Changwon 641010 South Korea

Carbide nucleation, growth and trapping behavior in directionally solidified MAR-M247 LC alloy and the corresponding mechanism have been investigated. Carbide forming element enrichment controls the carbide nucleation and the carbide growth behavior. If the carbide forming element enrichment and the nucleation sites are suitable, carbide nucleation can occur both above and below the liquids temperature. Heterogeneous carbide nucleation is the preferred nucleation mechanism at low carbide forming element enrichment. Carbide growth occurs mainly at inter-secondary gamma dendrite arm area and lower part of the mushy zone. the carbides are subsequently trapped at these positions after growing to a certain size. Some carbides are only partially trapped by the solid-liquid interface and the carbide growth accelerates after being partially trapped. A critical growth rate exists between 2 multiplied by 10** minus **6 m/s and 5 multiplied by 10** minus **6 m/s. the carbide volume fraction decreases in the directionally solidified part at slow growth rate which is caused by the lack of suitable growth site and the low trapping ability of the solid-liquid interface. (Edited author abstract) 16 Refs.

关键词： Nickel alloys

Investigation on the Microstructure Homogenization in a tiAl Based Alloy Prepared by Elemental Powder Metallurgy

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Journal of Materials Science & technology 1999年第6期15卷 527-530页

作者： Liu, y huang, By He, yH Wang, JN Cent S Univ Natl Key Lab Powder Met Changsha 410083 Hunan Peoples R China

A ti-48Al (at. pet) alloy prepared by elemental powder metallurgy (EPM) has been heat treated under various conditions. through optical and scanning electronic microscopy, EDAX, XRD analysis, and DtA, it was shown that the hot pressed microstructure consisted of alpha(2)-ti3Al and tiAl phases. the alpha(2)-ti3Al phase was island-like, and had a high stability and heredity in subsequent heat treatments. the supersaturation of Al in the island-like alpha-ti3Al phase strongly influenced the transformation of alpha(or alpha(2)) to alpha(2)/gamma lamellar colonies. After a heat treatment at 1380 degrees C for 0.5 h and 1000 degrees C for 8 h, a fully lamellar microstructure with a colony size of 50 mu m was obtained. this result indicates that a homogeneous composition and an equilibrium microstructure in EPM tiAl-base alloys can only be obtained after heat treatment at temperatures above alpha transus temperature (t-alpha).

关键词： titanium alloys

A COMPREHENSIVE MODEL OF LASER CLADDING By POWDER FEEDING

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Acta Metallurgica Sinica(English Letters) 2004年第1期17卷 21-27页

作者： y.L.huang G.y.Liang J.y.Su School of Materials Science and Engineering Xi'an Jiaotong University Xi'an 710049 ChinaSchool of Materials Science and Engineering Xi'an Jiaotong University Xi'an 710049 ChinaSchool of Materials Science and Engineering Xi'an Jiaotong University Xi'an 710049 China

A novel model was presented to predict the evolutionary development of cladding layer, and a method based on Lambert-Beer theorem and Mie's theory was adopted to treat the interaction between powder stream and laser beam. By using the continuum model and enthalpy-porosity method, the fluid flow and heat transfer in solid-liquid phase change system were simulated. the commercial software PHOENICS, to which several modules were appended, was used to accomplish the simulation. Numerical computation was performed for Stellite 6 cladding on steel, the obtained results are coincident with those measured in experiment basically.

关键词： laser cladding powder feeding cladding layer interaction

Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles

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Neural Regeneration Research 2025年第4期20卷 1124-1134页

作者： yanting Liu Wei huang Jiayi Wen Xin Xiong ting Xu Qi Wang Xiusheng Chen Xianxian Zhao Shihua Li Xiaojiang Li Weili yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong-Hongkong-Macao CNS Regeneration Institute of Jinan UniversityJinan UniversityGuangzhouGuangdong ProvinceChina

the vast majority of in vitro studies have demonstrated that PINK1 phosphorylates Parkin to work together in mitophagy to protect against neuronal ***,it remains largely unclear how PINK1 and Parkin are expressed in mammalian *** has been difficult to address because of the intrinsically low levels of PINK1 and undetectable levels of phosphorylated Parkin in small *** this issue is critical for elucidating the in vivo roles of PINK1 and ***,we showed that the PINK1 kinase is selectively expressed as a truncated form(PINK1–55)in the primate *** the present study,we used multiple antibodies,including our recently developed monoclonal anti-PINK1,to validate the selective expression of PINK1 in the primate *** found that PINK1 was stably expressed in the monkey brain at postnatal and adulthood stages,which is consistent with the findings that depleting PINK1 can cause neuronal loss in developing and adult monkey ***1 was enriched in the membrane-bound fractionations,whereas Parkin was soluble with a distinguishable *** double staining experiments showed that PINK1 and Parkin did not colocalize under physiological conditions in cultured monkey astrocytes,though they did colocalize on mitochondria when the cells were exposed to mitochondrial *** findings suggest that PINK1 and Parkin may have distinct roles beyond their well-known function in mitophagy during mitochondrial damage.

关键词： neurodegeneration Parkin Parkinson’s disease PINK1 subcellular distribution

HCV genotypes in hepatitis C patients and their clinical significances

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World Journal of Gastroenterology 1999年第6期5卷 547-549页

作者： huang F Zhao GZ Li y China Med Univ Affiliated Hosp 2 Dept Infect Dis Shenyang 110003 Liaoning Prov Peoples R China

INtRODUCtIONIt has been discovered that hepatitis C virus (HCV) presents considerable nucleotide variation and has many genotypes. At least twelve, 5 of which prevalent, i.e.: Ⅰ/1a, Ⅱ/1b, Ⅲ/2a, Ⅳ/2b, and Ⅴ/3a types. the different genotypes of HCV may possess some retationship with regional distribution, clinical manifestation, response to treatment and prognosis of HCV infection, thus to study the genotypes of HCV further in different areas is of practical value. We detected HCV genotypes in 94 patients with hepatitis C and in 6 patients with primary hepatocarcinoma by PCR assay with four kinds of type-specific primers with a view to study the distribution of HCV genotypes in hepatitis C in Shenyang area and their clinical significances.

关键词： hepatitis C hepatitis C virus genotyping

SIMULAtION OF tHE tHERMODyNAMIC QUANtItIES OF SELF-AVOIDING WALK CHAIN

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Chinese Chemical Letters 1996年第1期7卷 63-66页

作者： Zhao, DL Zhou, XD huang, y ACAD SINICA INST CHEMBEIJING 100080PEOPLES R CHINA BEIJING UNIV DEPT PHYSBEIJING 100871PEOPLES R CHINA

A Monte Carlo method has been proposed for direct simulating the thermodynamic quantities of a single self-avoiding walk chain with the neighbour interaction on a simple cubic lattice. the simulation data of the conformational entropy of the chain length 16 have been found to be consistent very well with the exact results obtained by the direct counting method.

关键词：

tHE　ALLOyING　BEHAVIOR　OF　BORON　AND　CARBON　INNi_3Al

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中国有色金属学会会刊：英文版 1997年第1期7卷 102-106页

作者： Zhang, y huang, J Lin, DL SHANGHAI JIAO tONG UNIV SHANGHAI 200030PEOPLES R CHINA

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ＴＨＥＡＬＬＯＹＩＮＧＢＥＨＡＶＩＯＲＯＦＢＯＲＯＮＡＮＤＣＡＲＢＯＮＩＮＮｉ３Ａｌ①ＺｈａｎｇＹｕｎ，ＨｕａｎｇＪｉｎ，ＬｉｎＤｏｎｇｌｉａｎｇＳｈａｎｇｈａｉＪｉａｏｔｏｎｇＵｎｉｖｅｒｓｉｔｙ，Ｓｈａｎｇｈａｉ２０００３０ＡＢＳＴＲＡＣＴＴｏｆ...

关键词： intermetallics Ni 3Al stoichiometry solid solution alloying lattice parameter

INFLUENCE OF ALLOyING ELEMENtS ON HyDROGEN DIFFUSION USING SCM-DV-X_α

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Acta Metallurgica Sinica(English Letters) 2004年第1期17卷 71-76页

作者： y.huang D.M.Xing School of Materials Science and Engineering Tianjin University Tianjin 300072 ChinaSchool of Physics Tianjin Normal UniversityTianjin 300071China

the influence of alloy composition (ti, Mn, tiN) on hydrogen diffusion in Fe was studied in detail using SCM-DV-Xα method. the voltage barriers were obtained via calculation on Fe clusters containing the alloy elements such as ti, Mn as well as the chemical compound tiN respectively. the results showed that ti element produced deep trap in Fe, decreasing the diffusion coefficient of hydrogen elements, Mn element did not produce deep trap in Fe, decreasing the diffusion coefficient slightly and tiN in Fe produced very deep "trap" decreasing the diffusion coefficient obviously. the calculation results were in agreement with experiment results.

关键词： hydrogen diffusion SCM-DV-Xα method cluster