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Synergistic fibroblast optimization: a novel nature-inspired computing algorithm

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Frontiers of Information technology & Electronic Engineering 2018年第7期19卷 815-833页

作者： t t DHIVYAPRABHA P SUBASHINI M KRISHNAVENI Department of Computer Science Avinashilingam Institute for Home Science and Higher Education for Women

the evolutionary algorithm, a subset of computational intelligence techniques, is a generic population-based stochastic optimization algorithm which uses a mechanism motivated by biological concepts. Bio-inspired computing can implement successful optimization methods and adaptation approaches, which are inspired by the natural evolution and collective behavior observed in species, respectively. Although all the meta-heuristic algorithms have different inspirational sources, their objective is to find the optimum(minimum or maximum), which is problem-specific. We propose and evaluate a novel synergistic fibroblast optimization(SFO) algorithm, which exhibits the behavior of a fibroblast cellular organism in the dermal wound-healing process. Various characteristics of benchmark suites are applied to validate the robustness, reliability, generalization, and comprehensibility of SFO in diverse and complex situations. the encouraging results suggest that the collaborative and self-adaptive behaviors of fibroblasts have intellectually found the optimum solution with several different features that can improve the effectiveness of optimization strategies for solving non-linear complicated problems.

关键词： Synergistic fibroblast optimization (SFO) Fitness analysis Convergence Benchmark suite Monk's dataset

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Summer Heat

英语沙龙（高中） 2015年第7期 62-64页

作者： Rich wallace Steve James

Seedy CD8+ t_(RM) cells in aging lungs drive susceptibility to pneumonia and sequelae

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Cellular & Molecular Immunology 2021年第4期18卷 787-789页

作者： Anukul t.Shenoy Joseph P.Mizgerd Pulmonary Center Boston University School of MedicineBostonMA 02118USA Department of Medicine Boston University School of MedicineBostonMA 02118USA Department of Microbiology Boston University School of MedicineBostonMA 02118USA Department of Biochemistry Boston University School of MedicineBostonMA 02118USA

Aging is a leading risk factor for pneumonia and subsequent comorbidities,including chronic pulmonary diseases.1 the underlying causes of age-related susceptibility to pneumonia-related morbidity and mortality are complex and poorly *** aging has been associated with many changes in diverse immune compartments,if and how aging affects resident immune cells in the lung have not been examined.

关键词： aging susceptibility subsequent

Performance Analysis of Intelligent Robust Facility Layout Design

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Chinese Journal of Mechanical Engineering 2017年第2期30卷 407-418页

作者： G MOSLEMIPOUR t S LEE Y t LOONG Department of Industrial Engineering Payame Noor University Faculty of Engineering and technology Multimedia University

Design of a robust production facility layout with minimum handling cost （MHC） presents an appropriate approach to tackle facility layout problems in a dynamic volatile environment, in which product demands randomly change in each planning period. the objective of the design is to find the robust facility layout with minimum total material handling cost over the entire multiperiod planning horizon. this paper proposes a new mathematical model for designing robust machine layout in the stochastic dynamic environment of manufacturing systems using quadratic assignment problem （QAP） formulation. In this investigation, product demands are assumed to be normally distributed random variables with known expected value, variance, and covariance that randomly change from period to period. the proposed model was verified and validated using randomly generated numerical data and benchmark examples. the effect of dependent product demands and varying interest rate on the total cost function of the proposed model has also been investigated. Sensitivity analysis on the proposed model has been performed. Dynamic programming and simulated annealing optimization algorithms were used in solving the modeled example problems.

关键词： Robust layout Dynamic stochastic environment Manufacturing system Dynamic programming

SARS-CoV-2-specific t cells in infection and vaccination

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Cellular & Molecular Immunology 2021年第10期18卷 2307-2312页

作者： Antonio Bertoletti Nina Le Bert Martin Qui Anthony t.tan Programme in Emerging Infectious Diseases Duke-NUS Medical SchoolSingaporeSingapore Singapore Immunology Network A*STARSingaporeSingapore

During viral infections,antibodies and t cells act together to prevent pathogen spread and remove virus-infected *** adaptive immunity can,however,also trigger pathological processes characterized by localized or systemic inflammatory *** protective and/or pathological role of virus-specific t cells in SARS-CoV-2 infection has been the focus of many studies in COVID-19 patients and in vaccinated ***,we review the works that have elucidated the function of SARS-CoV-2-specific t cells in patients and in vaccinated *** whether SARS-CoV-2-specific t cells are more linked to protection or pathogenesis is pivotal to define future therapeutic and prophylactic strategies to manage the current pandemic.

关键词： SARS-CoV-2 Vaccines t cells COVID-19

Wind energy conversion system using perturb&observe-based maximum power point approach interfaced with t-type three-level inverter connected to grid

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Clean Energy 2022年第4期6卷 534-549页

作者： Pranupa S A.t.Sriram S.Nagaraja Rao M S Ramaiah University of Applied Sciences BangaloreIndia

In this paper,the performance of a permanent magnet synchronous generator(PMSG)-based wind energy conversion system(WECS)supplied to an uncontrolled rectifier-fed boost converter(BC)interfaced with a three-phase t-type three-level inverter(tLI)has been *** proposed WECS involves three converters,namely an uncontrolled rectifier that is used for conversion from AC to DC;a BC supplied by a PMSG-fed rectifier used to enhance the voltage gain;and a grid-connected three-phase t-type tLI is proposed to eliminate power-quality issues with synchronization of grid voltage and *** main goal of this research is to model and control the grid-connected t-type tLI using a d-q synchronous frame for wind energy for regulating the DC-link voltage and transferring the generated wind power from the BC to the ***,the perturb&observe(P&O)-based maximum power point(MPP)approach is recommended to keep track of the MPP for a BC that is supplied from a PMSG-based WECS under constant and variable wind *** proposed PMSG-based WECS interfaced with grid-connected t-type tLI using d-q control has been computationally modelled,simulated and validated with constant and variable speeds using MAtLAB®and Simulink®.It is confirmed that the P&O-based MPP approach ensures maximum power for varying wind speeds,and the total harmonic distortion of the t-type tLI grid current value is 3.18%,which is within IEEE-519 ***,with grid synchronization,the power factor of the t-type tLI is maintained at unity to avoid power-quality issues.

关键词： boost converter grid synchronization perturb&observe t-type three-level inverter wind turbine

A density functional study on some cyclic N_(10) isomers

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Defence technology（防务技术） 2019年第2期15卷 154-161页

作者： Lemi türker Middle East technical University Department of Chemistry üniversiteler

Polynitrogen compounds, comprising only nitrogen atoms, are rare. they are considered as promising candidates of clean(green) high energy density materials because of their high energy content and their sole decomposition product is N_2. Extending the previous work which was on cyclic N_8 isomers, in this study some cyclic N_(10) isomers having 1-4 cycles are considered within the limitations of density functional theory at the levels of B3LYP/6-311++G(d,p) and B3LYP/cc-PVtZ. Some of the structures,including the monocyclic one, decompose by eliminating certain number of N_2 units while some remain intact. All the stable isomers(1-3, 6-8) investigated presently are highly endothermic that they are candidates for clean high energy materials. Certain quantum chemical properties, IR and UV-VIS spectra as well as the specific impulse values for the stable structures are reported.

关键词： Nitrogen Polynitrogen Density functional theory Isomers N10

Effect of magnesium on FOX-7 and its tautomers-A DFt treatment

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Defence technology（防务技术） 2018年第3期14卷 179-187页

作者： Lemi türker Middle East technical University Department of Chemistry üniversiteler

FOX-7 and its cisoid and transoid 1,5-tautomers as well as magnesium composites of all have been investigated quantum chemically within the restrictions of density functional theory(B3 LYP/6 e311ttG(d,p)). Certain physico-chemical and quantum chemical properties, energies, stabilities,calculated IR and UV-VIS spectra are discussed. the influence of magnesium atom is investigated. It has been found that in FOX-7 composites the magnesium is not a silent ingredient, but interacts with the organic constituents.

关键词： FOX-7 镁原子 DFt 物理化学药品性质稳定性成分外力

Exactness of penalization for exact minimax penalty function method in nonconvex programming

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Applied Mathematics and Mechanics(English Edition) 2015年第4期36卷 541-556页

作者： t.ANtCZAK Faculty of Mathematics and Computer Science University of Lódz

the exact minimax penalty function method is used to solve a noncon- vex differentiable optimization problem with both inequality and equality constraints. the conditions for exactness of the penalization for the exact minimax penalty function method are established by assuming that the functions constituting the considered con- strained optimization problem are invex with respect to the same function η （with the exception of those equality constraints for which the associated Lagrange multipliers are negative these functions should be assumed to be incave with respect to η）. thus, a threshold of the penalty parameter is given such that, for all penalty parameters exceeding this threshold, equivalence holds between the set of optimal solutions in the considered constrained optimization problem and the set of minimizer in its associated penalized problem with an exact minimax penalty function. It is shown that coercivity is not suf- ficient to prove the results.

关键词： exact minimax penalty function method minimax penalized optimizationproblem exactness of penalization of exact minimax penalty function invex function,incave function