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Machine learning-based comparison of factors influencing estimated glomerular filtration rate in Chinese women with or without nonalcoholic fatty liver

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World Journal of Clinical Cases 2024年第15期12卷 2506-2521页

作者： i-Chien Chen Lin-Ju Chou Shih-Chen Huang ta-Wei Chu Shang-Sen Lee Department of Nursing Kaohsiung Armed Forces General HospitalKaohsiung 802Taiwan Department of Obstetrics and Gynecology Tri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan Chief Executive Officer's Office MJ Health Research FoundationTaipei 114Taiwan Department of Urology Taichung Tzu Chi HospitalBuddhist Tzu Chi Medical FoundationTaichung 427Taiwan School of Medicine Tzu Chi UniversityHualian 970Taiwan Department of Urology Tri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan

BACKGROUND the prevalence of non-alcoholic fatty liver(NAFLD)has increased *** with NAFLD are known to have higher chance for renal function *** past studies used traditional multiple linear regression(MLR)to identify risk factors for decreased estimated glomerular filtration rate(eGFR).However,medical research is increasingly relying on emerging machine learning(Mach-L)*** present study enrolled healthy women to identify factors affecting eGFR in subjects with and without NAFLD(NAFLD+,NAFLD-)and to rank their *** to uses three different Mach-L methods to identify key impact factors for eGFR in healthy women with and without *** A total of 65535 healthy female study participants were enrolled from the taiwan MJ cohort,accounting for 32 independent variables including demographic,biochemistry and lifestyle parameters(independent variables),while eGFR was used as the dependent *** from MLR,three Mach-L methods were applied,including stochastic gradient boosting,eXtreme gradient boosting and elastic *** of estimation were used to define method accuracy,where smaller degree of error indicated better model *** income,albumin,eGFR,High density lipoprotein-Cholesterol,phosphorus,forced expiratory volume in one second(FEV1),and sleep time were all lower in the NAFLD+group,while other factors were all significantly higher except for smoking ***-L had lower estimation errors,thus outperforming *** Model 1,age,uric acid(UA),FEV1,plasma calcium level(Ca),plasma albumin level(Alb)and t-bilirubin were the most important factors in the NAFLD+group,as opposed to age,UA,FEV1,Alb,lactic dehydrogenase(LDH)and Ca for the *** the importance percentage was much higher than the 2nd important factor,we built Model 2 by removing *** the eGFR were lower in the NAFLD+group compared to the NAFLD-group,with age being was the most important impact factor in both groups of he

关键词： Non-alcoholic fatty liver Estimated glomerular filtration rate Machine learning Chinese women

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Near resonance vibration isolation on a levered-dual response(LEDAR)Coulomb-damped system by differential preloads/offsets in linear springs

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Applied Mathematics and Mechanics(English Edition) 2024年第6期45卷 1033-1050页

作者： t.i.tOLUWALOJU C.K.tHEiN D.HALiM Department of Mechanical Materials and Manufacturing EngineeringUniversity of Nottingham Ningbo ChinaNingbo 315100Zhejiang ProvinceChina Nottingham Ningbo China Beacons of Excellence Research and innovation institute University of Nottingham Ningbo ChinaNingbo 315048Zhejiang ProvinceChina

the levered-dual response(LEDAR)Coulomb-damped system attains near resonant vibration isolation by differential preloads/offsets in linear *** takes the advantages of both the preloads/offsets in linear springs and the guiderail friction for realizing different levels of vibration *** isolation capacities are investigated on the strategies with both the horizontal and vertical guiderails,with the horizontal rail only,and without *** compressive preloads generally result in the consumption of most of the initial excitation energy so as to overcome the potential *** isolation onsets at the frequency ratio of 1∓0.095 on the left-hand side(LHS)and the right-hand side(RHS)of the lever are relative to the load plate *** observed near resonant isolation thus makes the LEDAR system a candidate for the isolation of the mechanical systems about resonance while opening a path for simultaneous harvesterisolation functions and passive functions at extreme frequencies.

关键词： lever ratio Coulomb damping preload tension/compression isolation band/depth offset potential

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A robust vector tracking loop structure based on potential bias analysis

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Chinese Journal of Aeronautics 2024年第4期37卷 405-420页

作者： Qiongqiong JiA Yiran LUO Bing XU Li-ta HSU Renbiao WU tianjin Key Lab for Advanced Signal Processing Civil Aviation University of ChinaTianjin 300300China interdisciplinary Division of Aeronautical and Aviation Engineering The Hong Kong Polytechnic University999077Hong KongChina Department of Geomatics Engineering University of CalgaryCalgary T2N1N4Canada

this paper proposes a robust vector tracking loop structure based on potential bias analysis. the influence of four kinds of biases on the existing two implementations of Vector tracking Loops(VtLs) is illustrated by theoretical analysis and numerical simulations, and the following findings are obtained. Firstly, the initial user state bias leads to steady navigation solution bias in the relative VtL, while new measurements can eliminate it in the absolute VtL. Secondly, the initial code phase bias is transferred to the following navigation solutions in the relative VtL, while new measurements can eliminate it in the absolute VtL. thirdly, the user state bias induced by erroneous navigation solution of VtLs can be eliminated by both of the two VtLs. Fourthly,the multipath/NLOS likely affects the two VtLs, and the induced tracking bias in the duration of the multipath/NLOS would decrease the performance of VtLs. Based on the above analysis,a robust VtL structure is proposed, where the absolute VtL is selected for its robustness to the two kinds of initialization biases;meanwhile, the instant bias detection and correction method is used to improve the performance of VtLs in the duration of the multipath/NLOS. Numerical simulations and experimental results verify the effectiveness of the proposed robust VtL structure.

关键词： Global Navigation Satellite System(GNSS) Vector tracking Loop(VtL) Multipath Non-Line-of-Sight(NLOS) tracking bias propagation Least Absolute Shrinkage and Selection Operator(LASSO)

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Design,simulation,and testing of a tunable MEMS multi-threshold inertial switch

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Microsystems & Nanoengineering 2024年第2期10卷 37-46页

作者： Qiu Xu Rodrigo t.Rocha Yousef Algoos Eric Feron Mohammad i.Younis Faculty of Electronic information Engineering Huaiyin Institute of TechnologyHuai’an223003PR China Computer Electrical and Mathematical Science and Engineering DivisionKing Abdullah University of Science and TechnologyThuwal23955-6900Saudi Arabia Piezoelectric Microsystem technologies Silicon Austria LabsVillach9524Austria Physical Sciences and Engineering Division King Abdullah University of Science and TechnologyThuwal23955Saudi Arabia Mechanical Engineering Department State University of New YorkBinghamtonNY13902USA

this paper presents a tunable multi-threshold micro-electromechanical inertial switch with adjustable threshold *** demonstrated device combines the advantages of accelerometers in providing quantitative acceleration measurements and g-threshold switches in saving power when in the inactive state upon experiencing acceleration below the *** designed proof-of-concept device with two thresholds consists of a cantilever microbeam and two stationary electrodes placed at different positions in the sensing *** adjustable threshold capability and the effect of the shock duration on the threshold acceleration are analytically investigated using a nonlinear beam *** are shown for the relationships among the applied bias voltage,the duration of shock impact,and the tunable *** fabricated prototypes are tested using a shock-table *** analytical results agree with the experimental *** designed device concept is very promising for the classification of the shock and impact loads in transportation and healthcare applications.

关键词： tunable acceleration testing

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in vitro engineered models of neurodegenerative diseases

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BiOCELL 2024年第1期48卷 79-96页

作者： ZEHRA GÜL MORÇiMEN ŞEYMA taŞDEMiR AYLiN ŞENDEMiR Bioengineering Department Graduate School of Natural and Applied SciencesEge UniversityIzmir35040Türkiye Bioengineering Department Faculty of Engineering and Natural ScienceCelal Bayar UniversityManisa45110Türkiye Bioengineering Department Ege UniversityIzmir35040Türkiye Department of Biomedical technologies Graduate School of Natural and Applied SciencesEge UniversityIzmir35040Türkiye

Neurodegeneration is a catastrophic process that develops progressive damage leading to functional andstructural loss of the cells of the nervous system and is among the biggest unavoidable problems of our *** do not reflect the pathophysiology observed in humans due to distinct differences between the neuralpathways,gene expression patterns,neuronal plasticity,and other disease-related mechanisms in animals *** in vitro cell culture models are also not sufficient for pre-clinical drug testing in reflecting thecomplex pathophysiology of neurodegenerative ***,modern,engineered techniques are applied to developmulticellular,intricate in vitro models and to create the closest microenvironment simulating biological,biochemical,and mechanical characteristics of the in vivo degenerating *** tHiS review,the capabilities and shortcomings ofscaffold-based and scaffold-free techniques,organoids,and microfluidic models that best reflect neurodegeneration invitro in the biomimetic framework are discussed.

关键词： Neurodegenerative diseases in vitro models Scaffolds Organoids Microfluidic devices

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Development of endemicity and conservation importance indices for tropical forests and the floral diversity assessment of *** in Benguet,Philippines

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Journal of Mountain Science 2024年第3期21卷 786-804页

作者： Johndale Rein t.BULLONG Jim P.SiLVERiO Joanna i.ALAFAG Maricel A.GURON Jones t.NAPALDEt Department of Environmental Science Benguet State UniversityLa Trinidad 2601Philippines Department of Biology Benguet State UniversityLa Trinidad 2601Philippines

the scientific community faces the challenge of measuring progress toward biodiversity targets and indices have been traditionally ***,recent inventories in secondary tropical mountain forests using traditional biodiversity indices have yielded results that are indistinct with primary *** shows the need to develop complementary indices that goes beyond species count but integrates the distribution and conservation status of the *** study developed endemicity and conservation importance index for tropical forest that incorporated the distribution and conservation status of the *** indices were applied to ***,a remnant primary mossy forest in Buguias,Benguet,Philippines,that resulted to endemicity index of 81.07 and conservation importance index of *** these with secondary forest sites with comparable Shannon-Wiener,Simpson,Evenness and Margalef’s indices,our endemicity and conservation indices clearly differentiates primary forest(our study site)with higher values from secondary forests with much lower ***,we are proposing these indices for a direct but scientifically-informed identification of specific sites for conservation and protection in tropical ***,our study documented a total of 168 vascular plant species(79 endemic and 12 locally threatened species)in *** are of tropical elements for both generic and species levels with some temperate elements that could be attributed to the site's high elevation and semi-temperate *** are important baseline information for conservation plans and monitoring of tropical mossy forests.

关键词： Endemicity index Conservation importance index Cordillera Central Range Floristic element Jaccard index of Similarity

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Generalized time-dependent generator coordinate method for induced fission dynamics

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Frontiers of physics 2024年第4期19卷 1-12页

作者： B.Li D.Vretenar t.Nikšić J.Zhao P.W.Zhao J.Meng State Key Laboratory of Nuclear Physics and technology School of PhysicsPeking UniversityBeijing 100871China Physics Department Faculty of ScienceUniversity of Zagreb10000 ZagrebCroatia Center for Circuits and Systems Peng Cheng LaboratoryShenzhen 518055China

the generalized time-dependent generator coordinate method(tD-GCM)is extended to include pairing *** correlated GCM nuclear wave function is expressed in terms of time-dependent generator states and weight *** particle–hole channel of the effective interaction is determined by a Hamiltonian derived from an energy density functional,while pairing is treated dynamically in the standard BCS approximation with time-dependent pairing tensor and single-particle occupation *** the inclusion of pairing correlations,various time-dependent phenomena in open-shell nuclei can be described more *** model is applied to the description of saddle-to-scission dynamics of induced *** generalized tD-GCM charge yields and total kinetic energy distribution for the fission of 240Pu,are compared to those obtained using the standard time-dependent density functional theory(tD-DFt)approach,and with available data.

关键词： nuclear density functional theory generator coordinate method fission dynamics

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ion heat transport in electron cyclotron resonance heated L-mode plasma on the t-10 tokamak

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Plasma Science and technology 2024年第4期26卷 52-60页

作者： V.A.KRUPiN M.R.NURGALiEV A.R.NEMEtS i.A.ZEMtSOV S.D.SUNtSOV t.B.MYALtON D.S.SERGEEV N.A.SOLOVEV D.V.SARYCHEV D.V.RYJAKOV S.N.tUGARiNOV N.N.NAUMENKO National Research Centre“Kurchatov institute” Moscow 123182Russia Bauman Moscow State technical University Moscow 105005Russia institution“Project Center itER” Moscow 123098Russia JSC“SOLAR” Minsk 220034Belarus

Anomalous ion heat transport is analyzed in the t-10 tokamak plasma heated with electron cyclotron resonance heating(ECRH) in second-harmonic extra-ordinary mode. Predictive modeling with empirical scaling for Ohmical heat conductivity shows that in ECRH plasmas the calculated ion temperature could be overestimated, so an increase of anomalous ion heat transport is required. to study this effect two scans are presented: over the EC resonance position and over the ECRH power. the EC resonance position varies from the high-field side to the low-field side by variation of the toroidal magnetic field. the scan over the heating power is presented with on-axis and mixed ECRH regimes. Discharges with high anomalous ion heat transport are obtained in all considered regimes. in these discharges the power balance ion heat conductivity exceeds the neoclassical level by up to 10 times. the high ion heat transport regimes are distinguished by three parameters: the ratio te/ti, the normalized electron density gradient R/■, and the ion–ion collisionality νii~*. the combination of high te/ti, high νii~*, and R/■=6-10 results in values of normalized anomalous ion heat fluxes up to 10 times higher than in the low transport scenario.

关键词： tokamak L-mode electron cyclotron resonance heating ion heat transport

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Porphyrins,phthalocyanines,and related covalent-organic frameworks in the photochemical and electrochemical water splitting:A review

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Particuology 2024年第7期90卷 236-265页

作者： Oxana V.Kharissova Yolanda Peña Méndez Boris i.Kharisov Aleksandr LNikolaev Edith Luévano-Hipólito Lucy t.González Universidad Autónoma de Nuevo León Ave.Universidad s/nSan Nicolás de los GarzaNuevo León66455Mexico Department of Chemistry Moscow State UniversityVorobievy HillsMoscowRussia CONACYt-Universidad Autónoma de Nuevo León Facultad de Ingeniería Civil-Departamento de Ecomateriales y EnergíaCd.UniversitariaC.P.66455San Nicolás de los GarzaNLMexico tecnologico de Monterrey Escuela de Ingeniería y CienciasMonterreyNuevo León 64890Mexico tecnologico de Monterrey Centro del AguaMonterreyNuevo León 64890Mexico

in this review,the possibilities of photochemical and electrochemical water splitting(WS)using porphyrins,phthalocyanines,related macrocycles,and their metal complexes are *** efforts are being carried out in order to develop novel and cheap methods for water decomposition to generate inexhaustible greener energy sources(molecular hydrogen)instead of oil and *** processes of WS in heterogeneous and homogeneous media require novel photo-and electrocatalysts,in particular those on macrocycle basis.A high WS efficiency has been observed for porphyrins and phthalocyanines,showing their suitability both for HER and OER processes are available using these relative compounds for WS *** can be used in photocatalytic and electrocatalytic WS processes both in their free forms or as metal porphyrins/porphyrinates,mainly loaded on various inorganic materials,such as Au NPs,C_(3)N_(4),GaP,KtaO_(3),GaP,and so on,as part of porphyrin-containing polymers or on electrode surface as modifying coatings,being sometimes better than commercial catalysts,such as Pt/*** H2 evolution can be considerably depended on the shape of porphyrin particles;in particular,porphyrin nanowires can yield up to 20 times more H2 than its *** certain cases,both HER and OER can be driven in the same electrolyte using metal *** capacity of metal porphyrins to generate ROS(in particular,singlet oxygen 1O_(2))under ultrasonic treatment is known and can be successfully used for H_(2)O_(2) and O_(2) *** can be used in similar processes in free form or as composites with inorganic or organic counterparts,being immobilized on nanocarbons,metal oxides and salts,or simply dissolved in water acting in a homogeneous *** additional use of ultrasound can lead to better results due to the synergistic effect of the sonochemical treatment and ***-organic frameworks are also applied for WS purposes and are mainly based

关键词： Porphyrins Phthalocyanines COFs Water splitting Photocatalysis Electrocatalysis

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Hydroxyapatite composites with carbon allotropes:Preparation,properties,and applications

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Particuology 2024年第5期88卷 239-265页

作者： Boris i.Kharisov Oxana V.Kharissova Lucy t.González Yolanda Peña Méndez igor E.Uflyand idalia Gómez de la Fuente Universidad Autónoma de Nuevo León Ave.UniversidadCiudad UniversitariaSan Nicolás de los GarzaNuevo León 66455Mexico tecnologico de Monterrey Escuela de Ingeniería y CienciasMonterreyNuevo Leon 64890Mexico Department of Chemistry Southern Federal UniversityRostov-on-DonRussia

Hydroxyapatite(HA)and its composites with inorganic additives,dopants,and polymers is a rapidly developing branch in the materials *** particular,carbon allotropes are widely used in these composites being widely applied for medical *** a gap of insufficient generalization of recent achievements in the field of the HA/Carbon composites,in this review we present the state of the art of the field of HA composites and hybrids with classic carbon allotropes and *** composites are known for carbon nanotubes,nanofibers,graphene and its oxidized forms,as well as,in a lesser grade,for graphite,fullerenes,nanodiamonds,carbon nanofoams,*** composites can be fabricated by a variety of classic and less-common methods,such as co-precipitation(with or without ultrasonic treatment),CVD,hot isostatic pressing,hydrothermal,spark plasma sintering,biomimetic mineralization,thermal and plasma spray,electrochemical and electrophoretic deposition,self-assembling,3D printing,electrospinning,and lyophilisation,among *** of various synthesis techniques can be also carried out for composite *** or synthetic HA can be used as it is for further interaction with carbon allotropes or it can be first prepared and then reacted with carbon counterpart;similarly,carbon allotropes can be introduced into the interaction with HA directly or they can be first synthesized,in particular from *** biocompatible composites can be produced in the form of coatings,powders,and scaffolds and can additionally contain quantitative amounts of third phases,frequently natural or synthetic *** these composites,especially with O-containing functionalizing groups,HA disadvantages could be considerably decreased with simultaneous enhancement of mechanical properties,becoming similar to human bone,chemical stability and biocompatibility,as well as possessing antibacterial ***→G reduction and higher HA decoration were obs

关键词： Hydroxyapatite Carbon nanotubes Graphene Quantum dots Fullerenes Nanodiamonds

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