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国际医学放射学杂志 2022年第2期 243-243页

作者： S.M.Wang Y.Q.Sun R.M.Li N.Mao Q.Li t.t.jiang 林伟源

摘要目的对增强乳腺X线摄影（CEM）影像进行病灶周围区域影像组学分析，以鉴别乳腺良恶性病变。方法这项回顾性研究纳入2017年11月—2020年2月接受CEM的病

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Effect of lamellarization on the microstructure and mechanical properties of marine 10Ni5CrMoV steel

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 402-413页

作者： tao Zou Yanwu Dong Zhouhua jiang Shuyang Du Yushuo Li School of Metallurgy Northeastern UniversityShenyang 110819China Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819China Key Laboratory for Ecological Metallurgy of Multimetallic Ores(Ministry of Education) Northeastern UniversityShenyang 110819China

Multistage heat treatment involving quenching(Q),lamellarizing(L),and tempering(t)is applied to marine 10Ni5CrMoV *** microstructure and mechanical properties were studied by multiscale characterizations,and the kinetics of reverse austenite transformation,strain hardening behavior,and toughening mechanism were further *** lamellarized specimens possess low yield strength but high toughness,especially cryogenic *** leads to the development of film-like reversed austenite at the martensite block and lath boundaries,refining the martensite structure and lowering the equivalent grain *** analysis of austenite reversion based on the JMAK model shows that the isothermal transformation is dominated by the growth of reversed austenite,and the maximum transformation of reversed austenite is reached at the peak temperature(750℃).the strain hardening behavior based on the modified Crussard-Jaoul analysis indicates that the reversed austenite obtained from lamellarization reduces the proportion of martensite,significantly hindering crack propagation via martensitic transformation during the *** a consequence,the QLt specimens exhibit high machinability and low yield *** with the Qt specimen,the ductile-brittle transition temperature of the QLt specimens decreases from-116 to-130℃due to the low equivalent grain size and reversed austenite,which increases the cleavage force required for crack propagation and absorbs the energy of external load,*** work provides an idea to improve the cryogenic toughness of marine 10Ni5CrMoV steel and lays a theoretical foundation for its industrial application and comprehensive performance improvement.

关键词： 10Ni5CrMoV steel lamellarizing reversed austenite cryogenic toughness ductile-brittle transition temperature

Genes and proteins expressed at different life cycle stages in the model protist Euplotes vannus revealed by both transcriptomic and proteomic approaches

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Science China Life Sciences 2025年第1期68卷 232-248页

作者： Yaohan jiang Xiao Chen Chundi Wang Liping Lyu Saleh A.Al-Farraj Naomi A.Stover Feng Gao Key Laboratory of Evolution & Marine Biodiversity (Ministry of Education) and Institute of Evolution & Marine Biodiversity Ocean University of China Marine College Shandong University Zoology Department College of ScienceKing Saud University Department of Biology Bradley University Laboratory for Marine Biology and Biotechnology Qingdao Marine Science and Technology Center

Sexual reproduction first appeared in unicellular protists and has continued to be an essential biological process in almost all *** protists, which contain both germline and somatic genomes within a single cell, have evolved a special form of sexual reproduction called conjugation that involves mitosis, meiosis, fertilization, nuclear differentiation, genome rearrangement, and the development of unique cellular structures. the molecular basis and mechanisms of conjugation vary dramatically among ciliates, and many details of the process and its regulation are still largely unknown. In order to better comprehend these processes and mechanisms from an evolutionary perspective, this study provides the first comprehensive overview of the transcriptome and proteome profiles during the entire life cycle of the newly-established marine model ciliate Euplotes vannus. transcriptome analyses from 14 life cycle stages(three vegetative stages and 11 sexual stages) revealed over 26,000 genes that are specifically expressed at different stages, many of which are related to DNA replication,transcription, translation, mitosis, meiosis, nuclear differentiation, and/or genome rearrangement. Quantitative proteomic analyses identified 338 proteins with homologs associated with conjugation and/or somatic nuclear development in other ciliates, including dicer-like proteins, Hsp90 proteins, RNA polymerase Ⅱ and transcription elongation factors, ribosomal-associated proteins, and ubiquitin-related proteins. Four of these homologs belong to the PIWI family, each with different expression patterns identified and confirmed by Rt-qPCR,which may function in small RNA-mediated genome rearrangement. Proteins involved in the nonhomologous end-joining pathway are induced early during meiosis and accumulate in the developing new somatic nucleus, where more than 80% of the germline sequences are eliminated from the somatic genome. A number of new candidate genes and proteins likely t

关键词： sexual reproduction transcriptomic proteomic genome rearrangement PIWI NHEJ

Peripheral blood RNA biomarkers can predict lesion severity in degenerative cervical myelopathy

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Neural Regeneration Research 2025年第6期20卷 1764-1775页

作者： Zhenzhong Zheng Jialin Chen Jinghong Xu Bin jiang Lei Li Yawei Li Yuliang Dai Bing Wang Department of Spine Surgery The Second Xiangya Hospital of Central South UniversityChangshaHunan ProvinceChina

Degenerative cervical myelopathy is a common cause of spinal cord injury,with longer symptom duration and higher myelopathy severity indicating a worse *** numerous studies have investigated serological biomarkers for acute spinal cord injury,few studies have explored such biomarkers for diagnosing degenerative cervical *** study involved 30 patients with degenerative cervical myelopathy(51.3±7.3 years old,12 women and 18 men),seven healthy controls(25.7±1.7 years old,one woman and six men),and nine patients with cervical spondylotic radiculopathy(51.9±8.6 years old,three women and six men).Analysis of blood samples from the three groups showed clear differences in transcriptomic *** analysis identified 128 differentially expressed genes that were enriched in patients with neurological *** least absolute shrinkage and selection operator analysis,we constructed a five-gene model(tBCD,tPM2,PNKD,EIF4G2,and AP5Z1)to diagnose degenerative cervical myelopathy with an accuracy of 93.5%.One-gene models(tCAP and SDHA)identified mild and severe degenerative cervical myelopathy with accuracies of 83.3%and 76.7%,*** of two immune cell types(memory B cells and memory-activated CD4^(+)t cells)predicted levels of lesions in degenerative cervical myelopathy with 80%*** results suggest that peripheral blood RNA biomarkers could be used to predict lesion severity in degenerative cervical myelopathy.

关键词： biomarkers candidate genes degenerative cervical myelopathy gene expression analysis immune cell types neurological disabilities peripheral blood RNA profiles spinal cord injury

Impacts of the annual cycle of background SSt in the tropical Pacific on the phase and amplitude of ENSO

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 12-17页

作者： Song jiang Congwen Zhu Ning jiang State Key Laboratory of Severe Weather(LASW) Chinese Academy of Meteorological SciencesBeijingChina College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijingChina

the dominant annual cycle of sea surface temperature(SSt)in the tropical Pacific exhibits an antisymmetric mode,which explains 83.4%total variance,and serves as a background of El Niño-Southern Oscillation(ENSO).However,there is no consensus yet on its anomalous impacts on the phase and amplitude of *** on data during 1982-2022,results show that anomalies of the antisymmetric mode can affect the evolution of ENSO on the interannual scale via Bjerknes feedback,in which the positive(negative)phase of the antisymmetric mode can strengthen El Niño(La Niña)in boreal winter via an earlier(delayed)seasonal cycle transition and larger(smaller)annual *** magnitude of the SSt anomalies in the equatorial eastern Pacific can reach more than±0.3◦C,regulated by the changes in the antisymmetric mode based on random sensitivity *** reveal the spatial pattern of the annual cycle associated with the seasonal phase-locking of ENSO evolution and provide new insight into the impact of the annual cycle of background SSt on ENSO,which possibly carries important implications for forecasting ENSO.

关键词： Annual cycle SSt anomaly Antisymmetric mode ENSO

Crystallization Modulation and Holistic Passivation Enables Efficient two‑terminal Perovskite/CuIn(Ga)Se_(2)tandem Solar Cells

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Nano-Micro Letters 2025年第1期17卷 205-215页

作者： Cong Geng Kuanxiang Zhang Changhua Wang Chung Hsien Wu Jiwen jiang Fei Long Liyuan Han Qifeng Han Yi‑Bing Cheng Yong Peng State Key Laboratory of Advanced technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070People’s Republic of China triumph Photovoltaic Materials Co. Ltd.No.1001 Yannan AvenueHigh‑Tech Development DistrictBengbuAnhui 233000People’s Republic of China College of Materials Science and Engineering Guilin University of TechnologyGuilin 541004People’s Republic of China State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

two-terminal(2-t)perovskite(PVK)/CuIn(Ga)Se_(2)(CIGS)tandem solar cells(tSCs)have been considered as an ideal tandem cell because of their best bandgap matching regarding to Shockley–Queisser(S–Q)***,the nature of the irregular rough morphology of commercial CIGS prevents people from improving tandem device *** this paper,D-homoserine lactone hydrochloride is proven to improve coverage of PVK materials on irregular rough CIGS surfaces and also passivate bulk defects by modulating the growth of PVK *** addition,the minority carriers near the PVK/C60 interface and the incompletely passivated trap states caused interface recombination.A surface reconstruction with 2-thiopheneethylammonium iodide and N,N-dimethylformamide assisted passivates the defect sites located at the surface and grain ***,LiF is used to create this field effect,repelling hole carriers away from the PVK and C60 interface and thus reducing *** a result,a 2-t PVK/CIGS tandem yielded a power conversion efficiency of 24.6%(0.16 cm^(2)),one of the highest results for 2-t PVK/CIGS tSCs to our *** validation underscores the potential of our methodology in achieving superior performance in PVK/CIGS tandem solar cells.

关键词： PVK/CIGS tSCs Irregular rough surfaces Modulating the growth PVK/C60 interface recombination

Peptide photocaging:A brief account of the chemistry and biological applications

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Chinese Chemical Letters 2018年第7期29卷 1058-1062页

作者： Wing Ho So Clarence t.t.Wong jiang Xia Department of Chemistry The Chinese University of Hong Kong Hong Kong Special Administrative Region

Light is arguably the most convement non-invasive stimulant to perturb or control specinc cnemical reactions in the biological systems. Upon light illumination, photosensitive molecules incur conformational changes or formation/breaking of chemical bonds. Consequently, these molecules can be used to transfer signals from one location to another in the cell, from outside of the cell to the inside, or from a light bulb to the interior of animal tissues. the development of the photochemical reactions of organic compounds has paved the road towards their use in peptides and peptide-based biological applications. In this mini-review, we summarized the state-of-the-art development of photo-protecting groups for peptide photocaging including the un-caging mechanism of different PPGs, the synthesis of photo-caged peptides, and the recent applications of peptide photocaging in chemical biology.

关键词： Photo-protecting groups Photocaged peptides Photocaged proteins Photodecaging

Dynamically encircling an exceptional point in antiparity-time symmetric systems:asymmetric mode switching for symmetry-broken modes

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Light(Science & Applications) 2019年第1期8卷 376-384页

作者： Xu-Lin Zhang tianshu jiang C.t.Chan State Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchunChina Department of Physics The Hong Kong University of Science and TechnologyClear Water BayHong KongChina

Dynamically encircling an exceptional point(EP)in parity-time(Pt)symmetric waveguide systems exhibits interesting chiral dynamics that can be applied to asymmetric mode switching for symmetric and anti-symmetric *** counterpart symmetry-broken modes(i.e.,each eigenmode is localized in one waveguide only),which are more useful for applications such as on-chip optical signal processing,exhibit only non-chiral dynamics and therefore cannot be used for asymmetric mode ***,we solve this problem by resorting to anti-parity-time(anti-Pt)symmetric systems and utilizing their unique topological structure,which is very different from that of Pt-symmetric *** find that the dynamical encircling of an EP in anti-Pt-symmetric systems with the starting point in the Pt-broken phase results in chiral *** a result,symmetry-broken modes can be used for asymmetric mode switching,which is a phenomenon and application unique to anti-Pt-symmetric *** perform experiments to demonstrate the new wave-manipulation scheme,which may pave the way towards designing on-chip optical systems with novel functionalities.

关键词： symmetric asymmetric symmetry

Quantification of ventilation enhancement using the Eye CAN roof support

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International Journal of Mining Science and technology 2017年第1期27卷 153-158页

作者： Shook Michael t Sindelar Mark F, jiang Hua Luo Yi Burrell Mining Products Inc.New KensingtonPA 15068USA Department of Mining Engineering West Virginia UniversityMorgantownWV 26506USA

Convergence of roof and floor in underground mine openings is a common occurrence. this convergence not only adversely affects the ability of workers, equipment and supplies to travel through the mine, it also reduces the effectiveness of the mine ventilation system, which is essential for the dilution of methane gas and airborne respirable dust. While installing secondary standing supports to control floor and roof convergence, such supports, by nature, partially obstruct a portion of the airway. these added obstructions inhibit the ability of the ventilation system to operate as efficiently as it could by increasing the resistance in and reducing the cross-sectional area of the airway. this study introduces and demonstrates the benefits of the Eye CAN^(tM) standing roof support, which controls floor and roof convergence and is less obstructive to air flow than conventional wooden cribs. Laboratory findings show that the normal resistance of a supported lined airway is reduced by using this new product from Burrell Mining Products, Inc., while providing the same roof support characteristics of an established product—the CANò. Load vs. displacement curves generated from laboratory tests demonstrated that this new product behaves with the same roof support characteristics as others in the CAN product family. Ventilation data gathered from a simulated mine entry was then used for computational fluid dynamics(CFD) *** CFD analysis showed an improvement with the Eye CAN vs. other accepted forms of standing roof support. this proof-of-concept study suggests that, when using this new product made by Burrell Mining Products, Inc., not only will the convergence from the roof and floor be controlled, but airway resistance will also be reduced.

关键词： Standing roof support CAN Ventilation Load-displacement Eye CAN

Influences of residual stress and micro-deformation on microstructures and mechanical properties for ti-6.5Al-3.5Mo-1.5Zr-0.3Si alloy produced by laser powder bed fusion

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Journal of Materials Science & technology 2021年第16期75卷 174-183页

作者： C.C.Zhang H.L.Wei t.t.Liu L.Y.jiang t.Yang W.H.Liao National Joint Engineering Research Center of NC Forming technology and Equipment School of Mechanical EngineeringNanjing University of Science and TechnologyNanjing 210094China

Laser powder bed fusion(LPBF)yields unique advantages during the fabrication of titanium *** the present work,ti-6.5 Al-3.5 Mo-1.5 Zr-0.3 Si alloy specimens with excellent mechanical performances were fabricated by *** as-built specimens displayed relatively high strength and ductility under modest volume energy densities(VEDs),whereas they manifested high strength with low ductility under high *** investigate the key reason of this phenomenon,the specimens were designed with two VEDs ranges of 60 J/mm^(3) and 85 J/mm^(3).Special attention was paid to the influences of residual stress and micro-deformation on microstructures and mechanical properties for the first *** results indicated that the residual stresses and relative density of the 60 J/mm^(3) range specimens were higher than that of the 85 J/mm3 range *** multiplication and dislocation movement promoted by the residual stress were hindered by the initialα’phase grain boundary(prior-α’GB),leading to the formation ofα’metastable *** mean tensile strength and elongation of the 60 J/mm^(3) range specimens were 1248.1 MPa and 12.3%,respectively,whereas the corresponding values for the 85 J/mm^(3) range specimens were 1405.3 MPa,5.0%,*** deformation,the strength and ductility of the specimens were first improved by lamellar structures generated from prior-α’phases,and then effectively enhanced by the interaction between the{10–12}twins and ***,pores significantly reduced the ductility;hence,high VED specimens with large twins and numerous large pores increased the strength and reduce the ductility.

关键词： Laser powder bed fusion ti-6.5Al-3.5Mo-1.5Zr-0.3Si alloy Residual stress twin Mechanical properties