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用具有焦炭填充床的熔融还原工艺生产铁合金

铁合金 1993年第3期24卷 47-52,20页

作者： H.ItAYA S.tAGUCHI K.IGAWA t.nozaki 索淑芬日本千叶Kawasaki钢公司钢铁研究室

一个具有焦炭填充床的新熔融还原工艺,已发展成为用低品位焦炭和粉矿生产铁合金或生铁。这个工艺的特征是:(1)一个焦炭填充床竖炉;(2)两段式风口;(3)直接使用不烧结粉矿;(4)通过上部风口输送和喷射重力粉料;(5)流态化预还原炉对副产品... 详细信息

一个具有焦炭填充床的新熔融还原工艺,已发展成为用低品位焦炭和粉矿生产铁合金或生铁。这个工艺的特征是:(1)一个焦炭填充床竖炉;(2)两段式风口;(3)直接使用不烧结粉矿;(4)通过上部风口输送和喷射重力粉料;(5)流态化预还原炉对副产品废气充分利用。熔融还原的小型试验。

关键词：铁合金焦炭填充床熔融还原

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采用深度及角度相关分析法获得整个股骨软骨的t1ρ mapping

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国际医学放射学杂志 2016年第4期 464-464页

作者： t.nozaki Y.Kaneko H.J.Yu K.Kaneshiro R.Schwarzkopf t.Hara 钟怡 Department of Radiological Sciences University of California Irvine

摘要目的采用3D图像的角度及深度分析制作和评估正常人股骨软骨的t1ρ分布图像。方法收集20例健康志愿者的膝关节3.0 t MR t1ρmapping,由放射诊断科医生对整个股骨软骨进行分区。以软骨轮廓作为圆周,按设定圆心每4

关键词：骨软骨 mapping

Dixon两点算法MR量化分析肌肉脂肪变性预测肩袖全层撕裂修复后再撕裂1年期随访的初步经验

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国际医学放射学杂志 2016年第5期 574-574页

作者： t.nozaki A.tasaki S.Horiuchi J.Ochi J.Starkey t.Hara 辛鸿婕 Department of Radiology St Luke’s International Hospital

摘要目的探讨冈上肌全层撕裂术后再撕裂病人及术后无再撕裂者之间术前肌肉脂肪变性的程度、术后脂肪变性的纵向变化以及脂肪变性的差异。材料与方法此次前瞻性研究经伦理委员会批准并遵循人类研究委员会原则,签署知情同意书。纳入50例... 详细信息

摘要目的探讨冈上肌全层撕裂术后再撕裂病人及术后无再撕裂者之间术前肌肉脂肪变性的程度、术后脂肪变性的纵向变化以及脂肪变性的差异。材料与方法此次前瞻性研究经伦理委员会批准并遵循人类研究委员会原则,签署知情同意书。纳入50例冈上肌全层撕裂的病人[男18例、女32

关键词：脂肪变性程度脂肪分数 Dixon MR 撕裂点算法肩袖

Gamete Dialogs in Green Lineages

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Molecular Plant 2015年第10期8卷 1442-1454页

作者： toshiyuki Mori Hiroko Kawai-toyooka tomoko Igawa Hisayoshi nozaki Department of Biological Sciences Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-0033 Japan Graduate School of Horticulture Chiba University 648 Matsudo Matsudo Chiba 271-8510 Japan

Gamete fusion is a core process of sexual reproduction and, in both plants and animals, different sex gametes fuse within species. Although most of the molecular factors involved in gamete interaction are still unknown in various sex-possessing eukaryotes, reports of such factors in algae and land plants have been increasing in the past decade. In particular, knowledge of gamete interaction in flowering plants and green algae has increased since the identification of the conserved gamete fusion factor GENERAtIVE CELL SPECIFIC 1/HAPLESS 2 （GCS1/HAP2）. GCSl was first identified as a pollen generative cell-specific transmembrane protein in the lily （Lilium Iongiflorum）, and was then shown to function not only in flowering plant gamete fusion but also in various eukaryotes, including unicellular protists and metazoans. In addition, although initially restricted to Chlamydomonas, knowledge of gamete attachment in flowering plants was also acquired. this review focuses on recent progress in the study of gamete interaction in volvocine green algae and flowering plants and discusses conserved mechanisms of gamete recognition, attachment, and fusion leading to zygote formation.

关键词： sexual reproduction gamete fusion flowering plants green algae evolution

Effectiveness of entecavir in preventing hepatocellular carcinoma development is genotype-dependent in hepatitis B virus-associated liver cirrhosis

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World Journal of Hepatology 2021年第1期13卷 144-150页

作者： Kazuo tarao Akito nozaki Makoto Chuma Masataka taguri Shin Maeda Department of Gastroenterology Tarao’s Gastroenterological ClinicYokohama City 241-0821Japan Gastroenterological Center Yokohama City University Medical CenterYokohama 232-0024Japan Department of Data Science Yokohama City University School of Data ScienceYokohama 236-0004Japan Division of Gastroenterology Yokohama City University Graduate School of MedicineYokohama 236-0004Japan

BACKGROUND the oral nucleos(t)ide analogue,entecavir(EtV)was demonstrated to reduce the rate of hepatocellular carcinoma(HCC)in patients with hepatitis B virus(HBV)-associated liver ***,the reduction of HCC differs in various regions of the *** to investigate the reduction of HCC development due to EtV therapy by *** We surveyed the differences in HCC development following EtV treatment based on published articles using PubMed(2004-2019).RESULtS the regions with the most marked reduction in HCC development due to EtV therapy were Spain(1.0%/year)and Canada(Southern part,1.3%/year),and the most ineffective areas were South Korea(3.6%-3.8%/year),China(3.3%/year),taiwan(2.4%-3.1%/year),and Hong Kong(2.8%/year).Following EtV administration,the incidence of HCC in genotype D regions(1.89%±0.28%/year,mean±SE)was significantly lower than that in genotype C regions(2.91%±0.24%/year,Pth regard to the initial HBV-DNA level,in genotype C patients(average:5.61 Log10IU/mL)this was almost the same as that in genotype D patients(average:5.46 Log10IU/mL).Moreover,there was no association between the prevalence ratio of HBV and the incidence of HCC on EtV *** the effectiveness of EtV in preventing HCC development in HBV-associated liver cirrhosis is genotype-dependent.

关键词： Hepatocellular carcinoma Entecavir Genotype of hepatitis B virus Oral nucleos(t)ide analogue

t1ρ/t2 mapping and histopathology of degenerative cartilage in advanced knee osteoarthritis

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World Journal of Orthopedics 2017年第4期8卷 350-356页

作者： Benjamin S Kester Philip M Carpenter Hon J Yu taiki nozaki Yasuhito Kaneko Hiroshi Yoshioka Ran Schwarzkopf Division of Adult Reconstruction Department of OrthopaedicsNYU Langone Medical Center Hospital for Joint Diseases Department of Pathology University of California IrvineOrange Department of Radiological Sciences University of California IrvineOrange

AIM to investigate whether normal thickness cartilage in osteoarthritic knees demonstrate depletion of proteoglycan or collagen content compared to healthy *** Magnetic resonance(MR) images were acquired from5 subjects scheduled for total knee arthroplasty(tKA)(mean age 70 years) and 20 young healthy control subjects without knee pain(mean age 28.9 years). MR images of t1ρ mapping, t2 mapping, and fat suppressed proton-density weighted sequences were *** tKA each condyle was divided into 4 parts(distal medial, posterior medial, distal lateral, posterior lateral) for cartilage analysis. twenty specimens(bone and cartilage blocks) were examined. For each joint,the degree and extent of cartilage destruction was determined using the Osteoarthritis Research Society International cartilage histopathology assessment *** magnetic resonance imaging(MRI) analysis, 2 readers performed cartilage segmentation for t1ρ/t2 values and cartilage thickness *** Eleven areas in MRI including normal or near normal cartilage thickness were selected. the corresponding histopathological sections demonstrated mild to moderate osteoarthritis(OA). there was no significant difference in cartilage thickness in MRI between control and advanced OA samples [medial distal condyle, P = 0.461;medial posterior condyle(MPC), P = 0.352; lateral distal condyle, P = 0.654; lateral posterior condyle, P = 0.550],suggesting arthritic specimens were morphologically similar to normal or early staged degenerative *** t2 and t1ρ values from the MPC were significantly higher among the patients with advanced OA(P= 0.043). For remaining condylar samples there was no statistical difference in t2 and t1ρ values between cases and controls but there was a trend towards higher values in advanced OA patients. CONCLUSION though cartilage is morphologically normal or near normal, degenerative changes exist in advanced OA patients. these changes can be detected w

关键词： t1rho Osteoarthritis Magnetic resonance imaging Cartilage Knee

三角纤维软骨的超短回波时间(UtE)定量MR成像:摆位的差异

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国际医学放射学杂志 2019年第4期 505-506页

作者：吴越 A.Fujisaki t.Aoki H.Narimatsu C.Kuwahara A.nozaki K.Menuki Department of Radiology University of Occupational and Environmental Health

摘要目的比较分别在中立位、腕部尺骨屈曲和前臂内旋位获得的三角纤维软骨（tFC）超短时间回波（UtE）的t2*值。方法对10名健康志愿者使用8通道膝关节线圈在3t

关键词： UtE 三角纤维软骨回波时间 MR

Simultaneous measurements of aeroacoustic sounds and wall vibration for exploring the contribution of tooth vibration in the production of sibilant sounds/s/

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Journal of Biomedical Science and Engineering 2011年第2期4卷 83-89页

作者： Masanori Nakamura Kazunori nozaki Haruka takimoto Kazuya Nagamune Motoharu Fujigaki Shigeo Wada 不详

In order to understand the contribution of teeth vibration to the production of sibilant/s/, the pre-sent study was designed to develop a method of simultaneously measuring aeroacoustic sounds and the vibration of an obstacle. to measure the vibration without disturbing flow, the Michelson interferometer was employed. the flow channel, which had an obstacle wall inside of it, was fabricated such that it morphologically mimicked the simplified geometry of the oral cavity. Given airflows at a flow rate of 7.5 × 10–4 m3/s from the inlet, aeroacoustic sounds were generated. A spectrum analy-sis of the data demonstrated two prominent peaks in the sound at 1,300 and 3,500 Hz and one peak in the wall vibration at 3,500 Hz. the correlation in peak frequencies between the sound and wall vibration suggests that the sound at 3,500 Hz was induced by the wall vibration. In fact, the sound amplitude at 3,500 Hz decreased when the obstacle wall was thickened, which increased its rigidity (p t-test). the experimental results demonstrate that the developed techniques are capable of measuring aeroacoustic sound and obstacle wall vibration simultaneously, and suggest the potential to pave the way for detailed analysis of the production of sibilant sounds /s/.

关键词： Acoustic Measurement Vibration Measurement Michelson Interferometer Aeroacoustics Sibilant/s/

New scoring system in assessment of Hoffa's fat pad synovitis: A comparative study with established scoring systems

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World Journal of Radiology 2018年第11期10卷 162-171页

作者： Shigeo Hagiwara Albert Yang Shoichiro takao Yasuhito Kaneko taiki nozaki Hiroshi Yoshioka Department of Radiological Sciences University of California Irvine Medical Center

AIM to investigate the reliability of the established and new scoring methods for Hoffa's fat pad synovitis using magnetic resonance imaging(MRI).MEtHODS A total of 139 knees of 115 patients who underwent MRI of the knee with and without gadolinium contrast were enrolled in this study. Proton density(PD)-weighted, PD-weighted fat-suppressed(PD-FS), and postcontrast t1-weighted fat-suppressed(t1CE) images were used for evaluation. Using contrast and noncontrast images, our grading method for synovitis was performed to measure synovial thickness and signal intensity changes of the fat pad [Synovial membrane(SM) score], which was compared with the established methods,including MRI Osteoarthritis Knee Score(MOAKS), parapatellar synovitis score,Whole-Organ Magnetic Resonance Imaging Score(WORMS), and suprapatellar effusion diameter. Intraclass correlation coefficients(ICC) for intra and interobserver reproducibility and Spearman correlation coefficients(r) were calculated for the parapatellar synovitis score and each scoring *** All of the scores presented substantial to almost perfect intrareliability. Among three readers, effusion diameter had substantial to almost perfect interreliability(ICC = 0.68-0.81) and WORMS had substantial interreliability(ICC = 0.61-0.70).For two out of three readers, there was substantial interreliability for the thickness score in t1CE(ICC = 0.55-0.69), SM scores in t1CE(ICC = 0.56-0.78)and PD-FS(ICC = 0.51-0.79), and parapatellar synovitis score in t1CE(ICC =0.53-0.72). the parapatellar synovitis score was significantly correlated with the thickness score in t1CE(r = 0.70) and the SM score in t1CE(r = 0.81) and PD-FS(r = 0.65).CONCLUSION the newly proposed quantitative thickness score on t1CE and the semiquantitative SM score on t1CE and PD-FS can be useful for Hoffa's fat pad synovitis.

关键词： Magnetic resonance imaging Hoffa’s fat pad synovitis Semiquantitative score Quantitative score Scoring system