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在半绝缘衬底上制作的1.5μm波长范围InP/GaInAsP隐埋异质结构激光器

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微纳电子技术 1983年第2期 80-82页

作者： t.matsuoka 张华

在半绝缘InP衬底上制作了1.5μm波长范围的InP/GaInAsP隐埋异质结构(BH)激光器。在25℃和CW工作条件下,激光器的阈值电流低至38mA。这一结果与在n型InP衬底上制造的BH激光器的阈值电流几乎一样。

关键词：激光器波长范围异质结构光激射器电子器件 InP/GaInAsP 半绝缘衬底阈值电流

1.5μm波长范围室温连续波工作的DFB-BH GaInAsP/InP激光器

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微纳电子技术 1983年第2期 83-85页

作者： t.matsuoka 李学颜

1.5μm波长范围的分布反馈隐埋异质结构(DFB-BH)GaInAsP/InP激光器在热沉温度高达310K下实现了连续工作。得到了300K下55mA的阈值电流以及单纵模工作。

关键词：激光器热沉波长范围光激射器电子器件 DFB-BH GaInAsP/InP 连续波 InP

阿尔茨海默病松果体体积减小:回顾性MR成像的横断面研究

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国际医学放射学杂志 2018年第2期 219-220页

作者： t.matsuoka A.Imai H.Fujimoto Y.Kato K.Shibata K.Nakamura 邹繁洁 Department of Psychiatry Graduate School of Medical Science Kyoto Prefectural University of Medicine

摘要目的分别评价阿尔茨海默病(AD)病人、轻度认知功能障碍(MCI)病人及健康对照组的松果体体积,探究认知实验的结果和脑实质体积是否存在相关性。材料与方法

关键词：松果体阿尔茨海默病 MR

Development of new diagnostics based on LiF detector for pump-probe experiments

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Matter and Radiation at Extremes 2018年第4期3卷 197-206页

作者： t.Pikuz A.Faenov NOzaki t.matsuoka B.Albertazzi N.J.Hartley K.Miyanishi K.Katagiri S.Matsuyama K.Yamauchi H.Habara Y.Inubushi t.togashi H.Yumoto H.Ohashi Y.tange t.Yabuuchi M.Yabashi A.N.Grum-Grzhimailo A.Casner I.Skobelev S.Makarov S.Pikuz G.Rigon M.Koenig K.A.tanaka t.Ishikawa R.Kodama Graduate School of Engineering Osaka UniversitySuitaOsaka 565-0871Japan Joint Institute for High temperatures Russian Academy of SciencesMoscow 125412Russia Open and transdisciplinary Research Initiatives Osaka UniversitySuitaOsaka 565-0871Japan Photon Pioneers Center Osaka UniversitySuitaOsaka 565-0871Japan LULI e CNRS Ecole PolytechniqueCEA:Universite Paris-SaclayUPMC Univ Paris 06:Sorbonne Universites-F-91128 Palaiseau cedexFrance Helmholtz-Zentrum Dresden-Rossendorf Dresden 01328Germany Japan Synchrotron Radiation Research Institute Sayo-choSayo-gunHyogo 679-5198Japan RIKEN Spring-8 Center Sayo-choSayo-gunHyogo 679-5148Japan Skobeltsyn Institute of Nuclear Physics Lomonosov Moscow State UniversityMoscow 119991Russia Universite de Bordeaux-CNRS-CEA CELIA(Center Lasers Intenses et Applications)UMR 5107F-33405 TalenceFrance National Research Nuclear University MEPhI Moscow 115409Russia ELI-NP/IFN-HH Maqurele-Bucharest 077125 Romania ILE Osaka UniversitySuitaOsaka 565-0871Japan

We present new diagnostics for use in optical laser pump-X-ray Free Electron Laser(XFEL)probe experiments to monitor dimensions,intensity profile and focusability of the XFEL beam and to control initial quality and homogeneity of targets to be driven by optical laser pulse.By developing X-ray imaging,based on the use of an LiF crystal detector,we were able to measure the distribution of energy inside a hard X-ray beam with unprecedented high spatial resolution(~1 mm)and across a field of view larger than some millimetres.this diagnostic can be used in situ,provides a very high dynamic range,has an extremely limited cost,and is relatively easy to be implemented in pump-probe experiments.the proposed methods were successfully applied in pump-probe experiments at the SPring-8 Angstrom Compact free electron LAser(SACLA)XFEL facility and its potential was demonstrated for current and future High Energy Density Science experiments.

关键词： XFEL Shock waves Pump-probe experiments High energy density science X-ray spectroscopy X-ray imaging

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超强激光脉冲与低密度泡沫靶相互作用研究

超强激光脉冲与低密度泡沫靶相互作用研究

Radiofrequency ablation of lung tumors:a multicenter study in Japan-JIVROSG 0203-

2004年全国强场激光物理会议

作者：李玉同盛政明张杰马燕云金展 Z．L．Chen R．Kodama t.matsuoka M．tampo K．A．tanaka t．tsutsumi t．Yabuuchi 杜凯张厚琼张林唐永健中科院物理所光物理实验室中科院物理所光物理实验室中科院物理所光物理实验室中科院物理所光物理实验室中科院物理所光物理实验室 Institute of Laser Engineering Osaka University Institute of Laser Engineering Osaka University Institute of Laser Engineering Osaka University Institute of Laser Engineering Osaka University Institute of Laser Engineering Osaka University Institute of Laser Engineering Osaka University Institute of Laser Engineering Osaka University 中物院激光聚变研究中心中物院激光聚变研究中心中物院激光聚变研究中心中物院激光聚变研究中心

＜正＞引言当前超强激光产生的超热电子束远大于Alfven限,所以要想得到稳定的超热电子束的输运,背景冷电子回流必须能够满足电中性要求。固体靶中冷电子密度高,基本可以补偿目前所能产生的超热电子束传输。但是:实用级别的、满足快点火...

＜正＞引言当前超强激光产生的超热电子束远大于Alfven限,所以要想得到稳定的超热电子束的输运,背景冷电子回流必须能够满足电中性要求。固体靶中冷电子密度高,基本可以补偿目前所能产生的超热电子束传输。但是:实用级别的、满足快点火条件的超热电子束,其电子束密度和背景等离子体密度相当,此时冷电子回流不能平衡高密度超热电子流。泡沫靶背景电子密度低,可以补偿超热电子电中性的冷电子回流比固体靶中小,所以在目前的激光条件下,通过采用泡沫靶,可以模拟真实点火条件下的超热电子输运过程,加深对快点火概念的认识,了解低密度泡沫靶和固体靶相互作用的不同特点。

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Radiofrequency ablation of lung tumors:a multicenter study i...

SMALL ORGAN SIZE 1 and SMALL ORGAN SIZE 2/DWARF AND LOW-tILLERING Form aComplex to Integrate Auxin and Brassinosteroid Signaling in Rice

2009年世界肿瘤介入学术大会

作者： matsuoka t Okuma t Yamamoto A Nakamura K Department of Radiology Osaka City University Medical School

Background:Percutaneous radiofrequency(RF)ablation has been increasingly applied as a local treatment in various locations,including liver,lung,kidney,bone and breast.Image-guided RF ablation is a technically easy procedure to enable a pin-point treatment and is performed as a minimally invasive procedure for malignant tumors.However,there were only a few prospective clinical trial.this prospective multi-center phaseⅠ/Ⅱstudy was conducted to evaluate the safety and efficacy of percutaneoes RF ablation of lung tumors by 8 institutions of Japan Interventional Radiology in Oncology Group (IIVROSG).

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Molecular Plant 2017年第4期10卷 590-604页

作者： Ko Hirano Hideki Yoshida Koichiro Aya Mayuko Kawamura Makoto Hayashi tokunori Hobo Karma Sato-lzawa Hidemi Kitano Miyako Ueguchi-tanaka Makoto matsuoka Bioscience and Biotechnology Center Nagoya University Nagoya 464-8601 Japan

Although auxin and brassinosteroid （BR） synergistically control various plant responses, the molecular mechanism underlying the auxin-BR crosstalk is not wen understood. We previously identified SMOS1, an auxin-regulated APEtALA2-type transcription factor, as the causal gene of the small organ size 1 （smosl） mutant that is characterized by a decreased final size of various organs in rice. In this study, we identified another smos mutant, smos2, which shows the phenotype indistinguishable from smosl. SMOS2 was identical to the previously reported DWARF AND LOWotILLERING （DLt）, which encodes a GRAS protein involved in BR signaling. SMOS1 and SMOS2/DLt physically interact to cooperatively enhance transcriptional transactivation activity in yeast and in rice nuclei. Consistently, the expression of OsPHI-1, a direct target of SMOS1, is upregulated only when SMOS1 and SMOS2/DLt proteins are both present in rice ceils. taken together, our results suggest that SMOS1 and SMOS2/DLt form a keystone complex on auxin-BR signaling crosstalk in rice.

关键词： auxin brassinosteroid crosstalk rice transcription factor

Scirrhous hepatocellular carcinoma displaying atypical findings on imaging studies

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World Journal of Gastroenterology 2009年第18期15卷 2296-2299页

作者： Soo Ryang Kim Susumu Imoto taisuke Nakajima Kenji Ando Keiji Mita Katsumi Fukuda Ryo Nishikawa Yu-ichiro Koma toshiyuki matsuoka Masatoshi Kudo Yoshitake Hayashi Department of Gastroenterology Kobe Asahi HospitalKobe653-0801Japan Department of Radiology Osaka City University Medical SchoolOsaka545-8585Japan Department of Gastroenterology and Hepatology Kinki University School of MedicineOsaka-Sayama589-8511Japan Division of Molecular Medicine & Medical Genetics International Center for MedicalResearch and Treatment(ICMRT)Kobe University Graduate School of MedicineKobe650-0017Japan

We describe a 15-mm scirrhous hepatocellular carcinoma(HCC) in a 60-year-old man with B-type cirrhosis.Ultrasound disclosed a 15-mm hypoechoic nodule in segment 7.Contrast-enhanced US revealed heterogeneous,not diffuse,hypervascularity in the early phase and a defect in the Kupffer phase.Contrast-enhanced computed tomography(Ct) revealed a heterogeneous hypervascular nodule in the early phase and a low-density area in the late phase.Magnetic resonance imaging(MRI) revealed iso-to hypointensity at t1 and high intensity at t2-weighted sequences.Contrast-enhanced MRI also revealed a heterogeneous hypervascular nodule in the early phase and washout in the late phase.Super-paramagnetic iron oxide-MRI revealed a hyperintense nodule.Ct during hepatic arteriography and Ct during arterial portography revealed heterogeneous hyperattenuation and a perfusion defect,respectively.Based on these imaging findings the nodule was diagnosed as a mixed well-differentiated and moderately-differentiated HCC.Histologically,the nodule was moderately-differentiated HCC characterized by typical cytological and structural atypia with dense fibrosis.Immunohistochemically,the nodule was positive for heterochromatin protein 1 and alpha-smooth muscle actin,and negative for cytokeratin 19.From the above findings,the nodule was diagnosed as scirrhous HCC.Clinicians engaged in hepatology should exercise caution with suspected scirrhous HCC when imaging studies reveal atypical findings,as shown in our case on the basis of chronic liver disease.

关键词：原发性肝癌影像学表现非典型对比增强MRI 细胞角蛋白19 经肝动脉造影计算机断层扫描超顺磁性氧化铁

OsIDD2, a zinc finger and INDEtERMINAtE DOMAIN protein, regulates secondary cell wall formation

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Journal of Integrative Plant Biology 2018年第2期60卷 130-143页

作者： Peng Huang Hideki Yoshida Kenji Yano Shunsuke Kinoshita Kyosuke Kawai Eriko Koketsu Masako Hattori Sayaka takehara Ji Huang Ko Hirano Reynante Lacsamana Ordonio Makoto matsuoka Miyako Ueguchi-tanaka Bioscience and Biotechnology Center Nagoya University Nagoya 464-8601 Japan State Key Laboratory of Crop Genetics and Germplasm Enhancement Nanjing Agricultural University Nanjing 210095 China Graduate School of Agricultural and Life Sciences The University of Tokyo Tokyo 113-8657 Japan Plant Breeding and Biotechnology Division Philippine Rice Research Institute Maligaya Science City of Munoz 3119 The Philippines

Previously, we found 123 transcription factors（tFs） as candidate regulators of secondary cell wall（SCW）formation in rice by using phylogenetic and co-expression network analyses. Among them, we examined in this work the role of OsIDD_2, a zinc finger and indeterminate domain（IDD） family tF. Its overexpressors showed dwarfism, fragile leaves, and decreased lignin content, which are typical phenotypes of plants defective in SCW formation, whereas its knockout plants showed slightly increased lignin content.the RNA-seq and quantitative reverse transcription polymerase chain reaction analyses confirmed that some lignin biosynthetic genes were downregulated in the OsIDD_2-overexpressing plants, and revealed the same case for other genes involved in cellulose synthesis and sucrose metabolism. the transient expression assay using rice protoplasts revealed that OsIDD_2 negatively regulates the transcription of genes involved in lignin biosynthesis, cinnamyl alcohol dehydrogenase 2 and 3（CAD_2 and 3）, and sucrose metabolism, sucrose synthase 5（SUS_5）, whereas an Alpha Screen assay, which can detect the interaction between tFs and their target DNA sequences, directly confirmed the interaction between OsIDD_2 and the target sequences located in the promoter regions of CAD_2 and CAD_3. Based on these observations, we conclude that OsIDD_2 is negatively involved in SCW formation and other biological events by downregulating its target genes.

关键词： IDD Figure OsIDD2 a zinc finger and INDEtERMINAtE DOMAIN protein SCW

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