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第6届辐射研究与辐射工艺学术年会

作者： t. kuribayashi K. Ushida S. Kashiwagi R. Kuroda H. Hirama M. Kawaguchi Y. Hama M. Washio Advanced Research Institute for Science and Engineering (RISE) Waseda University. the Institute of Physical and Chemical Research. the Institute of Scientific and Industrial Research Osaka University.

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Ultraviolet-induced alloantigen-specific immunosuppression in transplant immunity

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World Journal of transplantation 2015年第1期5卷 11-18页

作者： tomohide Hori Kagemasa kuribayashi Kanako Saito Linan Wang Mie torii Shinji Uemoto taku Iida Shintaro Yagi takuma Kato Department of Hepato-Pancreato-Biliary and transplant Surgery Kyoto University Graduate School of MedicineKyoto 606-8507 Japan Department of Cellular and Molecular Immunology Mie University Graduate School of MedicineTsu 514-8507 Japan Department of Hematology and Medical Oncology Mie University Graduate School of MedicineTsu 514-8507 Japan

After the first observation of the immunosuppressive effects of ultraviolet(UV) irradiation was reported in 1974, therapeutic modification of immune responses by UV irradiation began to be investigated in the context immunization. UV-induced immunosuppression is via the action of regulatory t cells(tregs). Antigen-specific tregs were induced by high-dose UV-B irradiation before antigen immunization in many studies, as it was considered that functional alteration and/or modulation of antigen-presenting cells by UV irradiation was required for the induction of antigen-specific immunosuppression. However, it is also reported that UV irradiation after immunization induces antigen-specific tregs. UV-induced tregs are also dominantly transferable, with interleukin-10 being important for UV-induced immunosuppression. Currently, various possible mechanisms involving treg phenotype and cytokine profile have been suggested. UV irradiation accompanied by alloantigen immunization induces alloantigen-specific transferable tregs, which have potential therapeutic applications in the transplantation field. Here we review the current status of UV-induced antigen-specific immunosuppression on the 40th anniversary of its discovery.

关键词： Alloantigen Ultraviolet irradiation Donorspecific immunosuppression Interleukin-10 Regulatory t cells

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Construction of a new picosecond pulse radiolysis system at Waseda University

Construction of a new picosecond pulse radiolysis system at ...

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第6届辐射研究与辐射工艺学术年会

作者： t. kuribayashi K. Ushida R. Kuroda S. Kashiwagi M.Kobayashi M. Kawaguchi Y. Hama M. Washio

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Diagnosis and treatment of Keloids and Hypertrophic Scars—Japan Scar Workshop Consensus Document 2018

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Burns & trauma 2019年第1期7卷 356-395页

作者： Rei Ogawa Sadanori Akita Satoshi Akaishi Noriko Aramaki-Hattori teruyuki Dohi toshihiko Hayashi Kazuo Kishi taro Kono Hajime Matsumura Gan Muneuchi Naoki Murao Munetomo Nagao Keisuke Okabe Fumiaki Shimizu Mamiko tosa Yasuyoshi tosa Satoko Yamawaki Shinichi Ansai Norihisa Inazu toshiko Kamo Reiko Kazki Shigehiko kuribayashi Department of Plastic Reconstructive and Aesthetic SurgeryNippon Medical School1-1-5 Sendagi Bunkyo-kuTokyo 113-8603Japan Department of Plastic Surgery Wound Repair and RegenerationFukuoka UniversityFukuoka 814-0180Japan Department of Plastic Surgery Nippon Medical School Musashikosugi Hospital1-396 KosugichoNakahara-kuKawasaki-shiKanagawa 211-8533Japan Department of Plastic and Reconstructive Surgery Keio University School of Medicine35 ShinanomachiShinjuku-kuTokyo 160-8582Japan Department of Plastic and Reconstructive Surgery Faculty of Medicine and Graduate School of MedicineHokkaido UniversityKita-15Nishi-7Kita-kuSapporo 060-8638Japan Department of Plastic Surgery Tokai University School of Medicine4-1-1 KitakanameHiratsukaKanagawa 259-1292Japan Department of Plastic and Reconstructive Surgery Tokyo Medical University6-7-1 NishishinjukuShinjuku-kuTokyo 160-0023Japan Department of Plastic and Reconstructive Surgery Osaka Saiseikai Nakatsu Hospital2-10-39 ShibataKita-kuOsaka 530-0012Japan Department of Plastic Reconstructive and Aesthetic SurgeryIwate Medical University School of Medicine19-1 UchimaruMoriokaIwate 020-8505Japan Department of Plastic Surgery Oita University Hospital1-1 IdaigaokaHasamamachiYufu-shiOita 879-5503Japan Department of Plastic Surgery Showa University Fujigaoka Hospital1-30 FujigaokaAoba-kuYokohamaKanagawaJapan Department of Plastic and Reconstructive Surgery Japanese Red Cross Fukui Hospital2-4-1 TsukimiFukui 918-8501Japan Division of Dermatology and Dermatopathology Nippon Medical School Musashikosugi Hospital1-396KosugichoNakahara-kuKawasaki-shiKanagawa 211-8533Japan Faculty of Pharmaceutical Sciences Teikyo Heisei University4-21-2 NakanoNakano-kuTokyo 164-8530Japan Wakamatsu-cho Mental and Skin Clinic 9-4 Wakamatsu-choShinjyuku-kuTokyo 162-0056Japan Department of Radiation Oncology Nippon Medical School HospitalTokyo 113-8603Japan

there has been a long-standing need for guidelines on the diagnosis and treatment of keloids and hypertrophic scars that are based on an understanding of the pathomechanisms that underlie these skin fibrotic *** is particularly true for clinicians who deal with Asian and African patients because these ethnicities are highly prone to these *** contrast,Caucasians are less likely to develop keloids and hypertrophic scars,and if they do,the scars tend not to be *** ethnic disparity also means that countries vary in terms of their differential diagnostic *** lack of clear treatment guidelines also means that primary care physicians are currently applying a hotchpotch of treatments,with uneven *** overcome these issues,the Japan Scar Workshop(JSW)has created a tool that allows clinicians to objectively diagnose and distinguish between keloids,hypertrophic scars,and mature *** tool is called the JSW Scar Scale(JSS)and it involves scoring the risk factors of the individual patients and the affected *** tool is simple and easy to *** a result,even physicians who are not accustomed to keloids and hypertrophic scars can easily diagnose them and judge their *** JSW has also established a committee that,in cooperation with outside experts in various fields,has prepared a Consensus Document on keloid and hypertrophic scar treatment *** guidelines are simple and will allow even inexperienced clinicians to choose the most appropriate treatment *** Consensus Document is provided in this *** describes(1)the diagnostic algorithm for pathological scars and how to differentiate them from clinically similar benign and malignant tumors,(2)the general treatment algorithms for keloids and hypertrophic scars at different medical facilities,(3)the rationale behind each treatment for keloids and hypertrophic scars,and(4)the body site-specific treatment protocols for these *** believe that t

关键词： Keloid Hypertrophic scars Pathological scars Guideline Pathology Surgery Radiotherapy Steroid Laser

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以多层螺旋Ct作为参照,比较断层融合与胸部X线摄影术对早期发现肺气肿的诊断性能

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国际医学放射学杂志 2013年第5期 501-502页

作者： Y.Yamada M.Jinzaki M.Hashimoto E.Shiomi t.Abe S.kuribayashi 梁志莹 Department of Diagnostic Radiology Keio University School of Medecine

摘要目的以多层螺旋Ct（MDCt）作为参照,比较断层融合成像与胸部X线摄影术对肺气肿的诊断性能。方法 48例患有肺气肿及63例无肺气肿的病人,在同一天内均进行胸部MDCt、断层融合和X线摄影检查。2名未知结果的放射科医生独立地评估这些断... 详细信息

摘要目的以多层螺旋Ct（MDCt）作为参照,比较断层融合成像与胸部X线摄影术对肺气肿的诊断性能。方法 48例患有肺气肿及63例无肺气肿的病人,在同一天内均进行胸部MDCt、断层融合和X线摄影检查。2名未知结果的放射科医生独立地评估这些断层融合成像及X线影像有无肺气肿表现。以横断面、冠状面的MDCt影像作为参照标准,通过评估含有-950 HU或者更低（LAA950）的衰减值的肺体积百分比来决定肺气肿的程度。本实验中运用了受试者操作特征（ROC）分析及广义估计方程模型。结果 ROC分析显示

关键词：肺气肿融合成像肺疾病摄影术胸部躯干 Ct 诊断性能多层螺旋断层地质构造

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Comprehensive and innovative techniques for livertransplantation in rats: A surgical guide

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World Journal of Gastroenterology 2010年第25期16卷 3120-3132页

作者： tomohide Hori Justin H Nguyen Yasuhiro Ogura toshiyuki Hata Shintaro Yagi Ann-Marie t Baine Norifumi Ohashi Christopher B Eckman Aimee R Herdt Hiroto Egawa Yasutsugu takada Fumitaka Oike Seisuke Saka-moto Mureo Kasahara Kohei Ogawa Koichiro Hata taku Iida Yukihide Yonekawa Lena Sibulesky Kagemasa kuribayashi takuma Kato Kanako Saito Mie torii Naruhiko Sahara Naoko Kamo tomoko Sahara Motohiko Yasutomi Shinji Uemoto Department of Neuroscience Mayo Clinic Jacksonville Florida FL 32224 United States Division of Hepato-Pancreato-Biliary Transplant and Pediatric Surgery Department of Surgery Kyoto University HospitalSakyo-ku Kyoto 606-8507 Japan Division of transplant Surgery Department of Transplantation Mayo Clinic Jackson-ville Florida FL 32224 United States Institute for Laboratory Animal Science and Ex-perimental Surgery RWTH-Aachen University D-52074 AachenGermany Department of Cellular and Molecular Immu-nology Mie University Graduate School of Medicine Tsu Mie514-8507 Japan New Zealand Liver transplant Unit Auckland City Hospital Auckland 92024 New Zealand

AIM: to investigate our learning curves of orthotopic liver transplantation (OLt) in rats and the most important factor for successful surgery. MEtHODS: We describe the surgical procedures for our rat OLt model, and determined the operator learning curves. the various factors that contributed to successful surgery were determined. the most important surgical factors were evaluated between successful and unsuccessful ***: Learning curve data indicated that 50 cases were required for operator training to start a study. Operative time, blood loss, warm ischemic time, anhepatic phase, unstable systemic hemodynamic state, and body temperature after surgery significantly affected surgery success by univariate analysis, while the anhepatic phase was the most critical factor for success by multivariate analysis. CONCLUSION: OLt in rats is the only liver transplantation model that provides clinically relevant and reliable results. Shortened anhepatic phase is key to success in this model.

关键词： Animal model Liver transplantation Microsurgery Rat Reperfusion injury Ultra-microsurgery

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Development of picosecond pulse radiolysis system at Waseda University

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辐射研究与辐射工艺学报 2005年第2期23卷 69-69页

作者： t.kuribayashi K Ushida S Kashiwagi R Kuroda H Hirama M Kawaguchi Y Hama M Washio Advanced Research Institute for Science and Engineering Waseda UniversityTokyoJapan the Institute of Physical and Chemical Research Waseda UniversityTokyoJapan the Institute of Scientific and Industrial Research Osaka UniversityOsakaJapan

A compact pulse radiolysis apparatus using a BNL-type s-band photocathode RF gun is now under development at Waseda *** laser pulse is used for excitation of the photocathode and for generation of white light,which is... 详细信息

关键词： Pico-second pulse radiolysis system Data deconvolution

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尿白蛋白排泄率作为接受降压治疗患者的残余心血管病风险分层指标的效用

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中华高血压杂志 2021年第10期29卷 946-946页

作者：袁源(摘译) 郑武洪(审校) Kikuchi Y tanaka F Nakamura M tanno K Onoda t Ohsawa M Sakata K Omama S Ogasawara K Yonekura Y Itai K kuribayashi t Ishigaki Y Okayama A Asahi K 不详

接受降压药物治疗的患者,即使血压控制良好,与非高血压个体的理想风险水平相比,仍有较高的风险发展为动脉粥样硬化性心血管病(atherosclerotic cardiovascular disease,ASCVD)。本文研究假设残余风险可以根据尿白蛋白排泄率(urinary alb... 详细信息

接受降压药物治疗的患者,即使血压控制良好,与非高血压个体的理想风险水平相比,仍有较高的风险发展为动脉粥样硬化性心血管病(atherosclerotic cardiovascular disease,ASCVD)。本文研究假设残余风险可以根据尿白蛋白排泄率(urinary albumin excretion,UAE)进行分层。方法:共纳入13082例血压<160/100 mm Hg(1 mm Hg=0.133 kPa).

关键词：尿白蛋白排泄率残余风险降压治疗动脉粥样硬化性心血管病心血管病风险 UAE 血压控制风险水平

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