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thrombotic microangiopathy-like disorder after living-donor liver transplantation:A single-center experience in Japan

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World Journal of Gastroenterology 2011年第14期17卷 1848-1857页

作者： tomohide Hori toshimi Kaido Fumitaka Oike Yasuhiro Ogura Kohei Ogawa Yukihide Yonekawa Koichiro Hata Yoshiya kawaguchi Mikiko Ueda Akira Mori Yasutsugu takada Hiroto Egawa Atsushi Yoshizawa Shinji Uemoto Hajime Segawa Kimiko Yurugi takuma Kato Kanako Saito Linan Wan Mie torii Feng Chen Ann-Marie t Baine Lindsay B Gardner Departments of Hepato-pancreato-biliary Transplant and Pediatric Surgery Kyoto University Hospital Kyoto 606-8507 Japan Department of Critical Care Medicine Kyoto University Hospital Kyoto 606-8507 Japan Department of transfusion Medicine and Cell therapy Kyoto University Hospital Kyoto 606-8507 Japan Department of Cellular and Molecular Immunology Mie University Hospital Graduate School of Medicine Mie 514-8507 Japan Department of Neuroscience Mayo Clinic Florida FL 32224 United States

AIM:to investigate thrombotic microangiopathy (tMA)in liver transplantion,because tMA is an infrequent but life-threatening complication in the transplantation field. MEtHODS:A total of 206 patients who underwent living-donor liver transplantation (LDLt) were evaluated,and the tMA-like disorder (tMALD) occurred in seven recipients. RESULtS:these tMALD recipients showed poor outcomes in comparison with other 199 recipients. Although two tMALD recipients successfully recovered,the other five recipients finally died despite intensive treatments including repeated plasma exchange (PE) and re-transplantation. Histopathological analysis of liver biopsies after LDLt revealed obvious differences according to the outcomes. Qualitative analysis of antibodies against a disintegrin-like domain and metalloproteinase with thrombospondin type 1 motifs (ADAMtS-13) were negative in all patients. the fragmentation of red cells,the microhemorrhagic macules and the platelet counts were early markers for the suspicion of tMALD after LDLt. Although the absolute values of von Willebrand factor (vWF) and ADAMtS-13 did not necessarily reflect tMALD,the vWF/ADAMtS-13 ratio had a clear diagnostic value in all cases. the establishment of adequate treatments for tMALD,such as PE for ADAMtS-13 replenishment or treatments against inhibitory antibodies,must be decided according to each case. CONCLUSION:the optimal induction of adequate therapies based on early recognition of tMALD by the reliable markers may confer a large advantage for tMALD after LDLt.

关键词： thrombotic microangiopathy Liver transplan-tation von Willebrand factor A disintegrin-like domain and metalloproteinase with thrombospondin type 1 motifs Complication

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Superconductivity above 30 K Achieved in Dense Scandium

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Chinese Physics Letters 2023年第10期40卷 108-111页

作者：何鑫张昌玲李芷文张思佳冯少敏赵建发卢可闵保森彭毅望贤成宋静王鲁红 Saori I.kawaguchi 吉诚李冰刘浩哲 J.S.tse 靳常青 Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100190China Songshan Lake Materials Laboratory Dongguan 523808China Shanghai Advanced Research in Physical Sciences Shanghai 201203China Japan Synchrotron Radiation Research Institute SPring-8Sayo-gun Hyogo 679-5198Japan Center for High Pressure Science&technology Advanced Research Beijing 100094China Department of Physics University of SaskatchewanCanada

Superconductivity is one of most intriguing quantum phenomena,and the quest for elemental superconductors with high critical temperature(t_(c))is of great scientific significance due to their relatively simple material composition and the underlying *** we report the experimental discovery of densely compressed scandium(Sc)becoming the first elemental superconductor with t_(c)breaking into 30 K range,which is comparable to the t_(c)values of the classic La-Ba-Cu-O or LaFeAsO *** results show that t_(c)^(onset)of Sc increases from~3K at around 43GPa to~32K at about 283GPa(t_(c)^(zero)~31 K),which is well above liquid neon ***,measured t_(c)shows no sign of saturation up to the maximum pressure achieved in our experiments,indicating that t_(c)may be even higher upon further compression.

关键词： temperature mechanism superconductor

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Development of picosecond pulse radiolysis system at Waseda University

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辐射研究与辐射工艺学报 2005年第2期23卷 69-69页

作者： t Kuribayashi K Ushida S Kashiwagi R Kuroda H Hirama M kawaguchi Y Hama M Washio Advanced Research Institute for Science and Engineering Waseda UniversityTokyoJapan the Institute of Physical and Chemical Research Waseda UniversityTokyoJapan the Institute of Scientific and Industrial Research Osaka UniversityOsakaJapan

A compact pulse radiolysis apparatus using a BNL-type s-band photocathode RF gun is now under development at Waseda *** laser pulse is used for excitation of the photocathode and for generation of white light,which is... 详细信息

关键词： Pico-second pulse radiolysis system Data deconvolution

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颈动脉内膜切除术治疗颈内动脉狭窄所致慢性眼缺血综合征的疗效

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中国微侵袭神经外科杂志 2001年第2期6卷 81-81页

作者：古莉 kawaguchi S Okuno S Sakaki t

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胰腺导管腺癌动脉侵犯的确诊：Ct的最佳诊断标准是什么？

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国际医学放射学杂志 2023年第4期 491-491页

作者： Y.Noda N.Mizuno N.Kawai t.Ando M.kawaguchi S.Nagata 肖诗蕾

摘要目的研究确定胰腺导管腺癌（PDAC）动脉侵犯的诊断效能和观察者间变异性，并确定最佳Ct成像标准。方法回顾性收集128例术前接受Ct增强扫描的PDAC病人（男

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Infrared study on pressure induced charge delocalization in Cs2tCNQ3

Infrared study on pressure induced charge delocalization in ...

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18th International Conference on High Pressure Science and technology

作者： Hasanudin t.Kagayama N.Kuroda t.Sugimoto Department of Mechanical Engineering and Materials Science Faculty of EngineeringKumamoto UniversityKumamoto 860-0855Japan Department of Mechanical Engineering and Materials Science Faculty of EngineeringKumamoto UniversityKumamoto 860-0855Japan Department of Mechanical Engineering and Materials Science Faculty of EngineeringKumamoto UniversityKumamoto 860-0855 Japan CRESTJapan Science and Technology CorporationKawaguchi 332-0012Japan Research Institute for Advanced Science and technology Osaka Prefecture UniversitySakai 599-8570Japan

＜正＞Cs2tCNQ3 crystallizes into a columnar structure consisting of a periodic stack of tCNQ0/tCNQ/tCNCt, resulting in a semiconductor with the lowest optical energy gap of 0.3 eV [1]. the radicals tCNQ are dimerized, so that the uppermost valence band is formed by the π* orbit of spin singlet. Since the on-site repulsion energy U ≈ 1.2 eV of the π* electrons is higher than the optical energy gap, Cs2tCNQ3 may be regarded as a charge-transfer semiconductor of the 1/3-filled Hubbard system. It has been reported that this material undergoes the phase transition to a metallic state at around 3 GPa [2], although the optical energy gap remains unclosed [1]. In the present work, to obtain information about the mechanism of this semiconductor-to-metal transition, we measure the pressure dependence of the infrared molecular vibration. Figure 1 shows the absorption spectra in the C-CN stretching region at several pressures. the features at 1205 and 1211 cm-1 at the ambient pressure arise from neutral and radical molecules, respectively, whereas the one at 1183 cm-1 is the electron-molecular-vibration （e-mv） coupled mode. the former two features show a blue-shift with increasing pressure, while increasing their energy spacing. At around 3.6 GPa they abruptly displace toward each other about half the way of the energy spacing, showing that the π* electrons delocalize significantly from radical to neutral molecules. Evidently this is related to the high electric conductivity at high pressures. It is noteworthy that in the high-pressure phase radical-like and neutral-like molecules still coexist spectroscopically, and thus the π* electrons are not completely delocalized. the frequency, on the other hand, of the e-mv mode remains almost unchanged at low pressures. the e-mv mode disappears above 3.6 GPa, in coincidence with the disappearance of the electronic band S1, which is the counterpart of the e-mv mode [1].

关键词： tCNQ compound semiconductor -to- metal transition molecular vibration

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通过药物应激心肌显像对血管内手术术前进行危险分层

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世界核心医学期刊文摘（心脏病学分册） 2005年第4期1卷 35-35页

作者： Harafuji K. Chikamori t. kawaguchi S. 腾增辉

to stratify perioperative cardiac risk for endovascular surgery, pharmacologic stress single-photon emission computed tomography(SPECt) was performed in 206 patients. Of 8 patients who had cardiac events, 7 occurred in 67 patients with p ositive SPECt results, whereas only 1 occurred in 139 patients with negative SPE Ct results(7 of 67 vs 1 of 139, pthermore, a scintigraphic marker o f a summed stress score the most important factor identifying patients who subsequently had cardiac events by multivariate analysis.

关键词：危险分层心肌显像心脏事件围手术期多变量分析

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D-青霉胺改善1例肝脏Wilson病患者腹腔镜和组织学检查结果:Wilson病Coombs阴性溶血性贫血3年随访

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世界核心医学期刊文摘（胃肠病学分册） 2005年第11期1卷 58-58页

作者： Sakaida I. kawaguchi K. Kimura t. 李宏宇 Department of Gastroenterology and Hepatology School of Medicine Yamaguchi University 1- 1- 1 Minami-Kogushi Ube 755- 8505 Japan

We report a 13- year-old girl who presented with hepatic failure and hemolytic anemia. Laboratory findings showed a normal serum copper level (104μ g/dl), high urinary copper level (2370μ g/dl), and low serum ceruloplasmin level (14.3μ g/dl). Slit-lamp examination revealed Kays-er-Fleischer rings on her cornea, and she was diagnosed with Wilson’s disease. Plasma exchange and continuous hemodiafiltration relieved the serious condition, after that laparoscopic examination was performed. Administration of D-penicillamine and restriction of dietary copper (tarted, leading to a normalized serum alanine amino transferase (ALt) level. After 3 years, she again underwent laparoscopic examination, and the laparoscopic and histological findings of her liver were obviously improved. Management of the copper level can reverse severe liver fibrosis in Wilson’s disease.

关键词： Wilson病Coombs 青霉胺组织学检查溶血性贫血腔镜肝豆状核变性凯-弗环血浆铜蓝蛋白腹腔镜检查血清铜

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UV-Polarizing Linear Polyyne Molecules Aligned in PVA

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Chinese Journal of Chemical Physics 2019年第2期32卷 175-181,I0002页

作者： R. Sata H. Suzuki N. Ueno Y. Morisawa M. Hatanaka t. Wakabayashi Department of Chemistry Kindai University Higashi-Osaka 577-8502 Japan Institute for Research Initiatives Graduate School of Science and Technology and Data Science Center Nara Institute of Science and Technology (NAIST) Ikoma 630-0192 Japan PREStO Japan Science and Technology Agency (JST) Kawaguchi 332-0012 Japan

Electronic absorption bands of conjugated linear carbon chain molecules, namely polyynes H(C≡C)nH (n=5-7), are exploited to devise light-polarizing films applicable to the UV. Laser ablated polyynes are separated in size and dispersed in a film of polyvinyl alcohol (PVA), which is stretched to align the trapped linear polyyne molecules inside. As a nature of the structural anisotropy, transition dipole of the UV absorption for polyyne molecules is in parallel with the molecular axis and the absorption occurs only for the electromagnetic wave having the amplitude of its electric vector along the molecular axis. Aligned and fixed orientationally in the solid PVA film, polyyne molecules act as selective absorbers of one of the polarization components of incident light at particular wavelength. Using a light source of linearly polarized UV light, whose direction of polarization is rotatable, angular dependence of the absorption intensity is investigated for the stretched PVA film containing aligned polyyne molecules and analyzed in terms of an order parameter in the theory of linear dichroism.

关键词： Polyyne UV absorption Polyvinyl alcohol Linear dichroism Linearly polarized light Polarizer

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胼胝体的角度在诊断特发性正常压力脑积水中的临床影响

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国际医学放射学杂志 2009年第1期32卷 93-93页

作者： K. Ishii t. Kanda A. Harada N. Miyamoto t. kawaguchi K. Shimada 李志明 Department of Radiology and Nuclear Medicine HyogoBrain and Heart Center 520 Saisho -Ko Himeji Hyogo 670 -0981 Japan

研究胼胝体角度的测量在诊断特发性正常压力脑积水（INPH）中的价值。对34例INPH病人、34例阿尔茨海默病（AD）病人及34例正常对照组（NC）受试者进行三维MRI检查。在后联合垂直于前后联合平面的冠状位MRI上测量所有受试者胼胝体的角度... 详细信息

研究胼胝体角度的测量在诊断特发性正常压力脑积水（INPH）中的价值。对34例INPH病人、34例阿尔茨海默病（AD）病人及34例正常对照组（NC）受试者进行三维MRI检查。在后联合垂直于前后联合平面的冠状位MRI上测量所有受试者胼胝体的角度。INPH组病人的胼胝体角度（平均值±标准差：66°±14°）显著小于AD组（104°±15°）及NC组（121°±11°）。

关键词：胼胝体角度特发性正常压力脑积水 MRI 阿尔茨海默病

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