检索结果-南通市图书馆

国际结核病与肺部疾病杂志 1995年第2期 81-87页

作者： J.Dhillon J.M.Dickinson J.A.Guy t.k.ng D.A.Mitchison 王撷秀 Department of Bacteriology Royal Postgraduate Medical School London UK and Yung Fung Shee Memorial Centre Kowloon Hong Kong

在实验性鼠结核病中,通过脾脏的活菌计数对长效利福霉素,利福喷丁(RPE)和FCE22807(FCE)的有效性进行了研究。用结核分支杆菌H37R_v株感染两周后,采用异烟肼25mg/kg、利福平10mg/kg和吡嗪酰胺150mg/kg,每日给药进行治疗持续6周。此后将... 详细信息

在实验性鼠结核病中,通过脾脏的活菌计数对长效利福霉素,利福喷丁(RPE)和FCE22807(FCE)的有效性进行了研究。用结核分支杆菌H37R_v株感染两周后,采用异烟肼25mg/kg、利福平10mg/kg和吡嗪酰胺150mg/kg,每日给药进行治疗持续6周。此后将小鼠分组,给RPE或FCE间隔分别为1周、2周或3周,化疗18周和24周后进行脾脏活菌计数。实验1显示RPE的剂量很有效,在每周给药1次的方案中,16mg/kg的剂量迅速灭菌,10mg/kg灭菌作用不十分迅速,6.25mg/kg作用不完全。RPE每2周或3周给药作用小,每2周给药16mg/kg其作用尽管与6mg/kg每周给药相同。第二个实验比较了RPE和FCE每次给药12mg/kg或8mg/kg。8mg/kg每2周或3周给药结果相似,尽管FCE较RPE作用稍强。血清分析表明8mg/kg及12mg/kgFCE的血清水平甚至低于6.25mg/kgRPE所产生的水平。这提示如果FCE的生物利用度可以提高,该药可能是较RPE更好的药物,并且服用16mg/kgRPE后的血清水平与人服用8mg/kg同时摄入富有脂肪的食物后的水平相似,提示在人类治疗中有效的2周给药1次的良好前景,对长效利福霉素在肺结核治疗管理中可能发挥的作用进行了讨论。

关键词：利福霉素利福喷丁利福平藤黄八迭球菌金黄色葡萄球菌 3周给药小鼠 tuberculosis 活菌计数实验性

High-Performance and Large-Area Inverted Perovskite Solar Cells Based on NiO_(x) Films Enabled with A Novel Microstructure-Control technology

在线全文

学校读者我要写书评

暂无评论

Energy & Environmental Materials 2024年第1期7卷 153-159页

作者： Guibin Shen Xin Li Yuqin Zou Hongye Dong Dongping Zhu Yanglin Jiang Xin Ren ng Fen Lin Peter Müller-Buschbaum Cheng Mu key Laboratory of Advanced Light Conversion Materials and Biophotonics Department of ChemistryRenmin University of ChinaBeijing 100872China Solar Energy Research Institute of Singapore(SERIS) National University of SingaporeSingapore 117574Singapore Physik-Department Lehrstuhl für Funktionelle MaterialienTechnische Universität MünchenJames-Franck-Straße 185748Garching Germany Heinz Maier-Leibnitz Zentrum(MLZ) Technische Universität MünchenLichtenbergstr.185748Garching Germany

the improvement in the efficiency of inverted perovskite solar cells(PSCs)is significantly limited by undesirable contact at the NiO_(x)/perovskite *** this study,a novel microstructure-control technology is proposed for fabrication of porous NiO_(x)films using Pluronic P123 as the structure-directing agent and acetylacetone(AcAc)as the coordination *** synthesized porous NiO_(x)films enhanced the hole extraction efficiency and reduced recombination defects at the NiO_(x)/perovskite ***,without any modification,the power conversion efficiency(PCE)of the PSC with MAPbl_(3)as the absorber layer improved from 16.50%to 19.08%.Moreover,the PCE of the device composed of perovskite Cs0.05(MA_(0.15)FA_(0.85))_(0.95)Pb(I_(0.85)Br_(0.15))_(3)improved from 17.49%to 21.42%.Furthermore,the application of the fabricated porous NiO_(x)on fluorine-doped tin oxide(FtO)substrates enabled the fabrication of large-area PSCs(1.2 cm^(2))with a PCE of 19.63%.this study provides a novel strategy for improving the contact at the NiO_(x)/perovskite interface for the fabrication of high-performance large-area perovskite solar cells.

关键词： interfacial contact inverted and large-area perovskite solar cells photovoltaic materials porous NiO_(x)films renewable energy

Predictors of the placebo response in a nutraceutical randomized controlled trial for depression

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Medicine 2024年第1期22卷 46-53页

作者： Rosemary Arnold Jenifer Murphy-Smith Chee H.ng David Mischoulon Gerard J.Byrne Chad A.Bousman Con Stough Michael Berk Jerome Sarris Professorial Unit the Melbourne ClinicDepartment of PsychiatryUniversity of MelbourneRichmond 3121Australia Depression Clinical and Research Program Department of PsychiatryMassachusetts General HospitalHarvard Medical SchoolBostonMA 02115USA Faculty of Medicine Discipline of PsychiatryCentre for Clinical ResearchRoyal Brisbane&Women’s HospitalHerstonthe University of QueenslandBrisbane 4006Australia Departments of Medical Genetics PsychiatryPhysiology&Pharmacology and Community Health SciencesUniversity of CalgaryCalgaryAB T2N 1N4Canada Department of Psychiatry the University of MelbourneMelbourne 3052Australia Centre for Human Psychopharmacology Swinburne UniversityMelbourne 3122Australia the Institute for Mental and Physical Health and Clinical translation School of MedicineBarwon HealthDeakin UniversityGeelong 3220Australia the Centre of Excellence in Youth Mental Health the University of MelbourneParkville 3052Australia Florey Institute of Neuroscience and Mental Health the University of MelbourneParkville 3052Australia NICM Health Research Institute Western Sydney UniversityWestmeadNSW 2145Australia

Objective the placebo response in depression studies is the change in symptoms amongst those who receive an inactive *** well-designed randomized controlled trials(RCts)of depression have a high proportion of placebo responders,with little understanding as to *** present study assesses characteristics associated with the placebo response in a nutraceutical trial with a large proportion of placebo *** this is a secondary analysis of a nutraceutical depression RCt which identified no overall treatment benefit relative to placebo(n=69 in placebo group).We investigated participant characteristics such as socio-demographics,clinical features,and recruitment methods,and their association with the placebo *** genetic polymorphisms were also *** response was measured based on change in Montgomery-Asberg Depression Rating Scale *** association of these hypothesis-driven variables of interest and the placebo response was examined using linear mixed effects *** Greater levels of education,particularly pursuing post-high school education,better self-reported general health,marriage/de facto,greater improvement in the first trial week,and more failed antidepressant therapies in the current depressive episode were associated with greater placebo *** increased placebo response was not found in those recruited via social media nor in those with concomitant antidepressant *** nucleotide polymorphisms from the tryptophan hydroxylase 1(tPH1)gene(A779C and A218C)were weakly associated with greater placebo response,although the evidence was attenuated after accounting for multiple *** this is,to our knowledge,the first study within nutraceutical research for depression to assess the association between participant characteristics and variation in the placebo *** variables appeared to predict the placebo *** findings may encourage future trial design

关键词： Randomized controlled trial Placebo Depression Nutraceutical Psychiatry

miniSCIDOM: a scintillator-based tomograph for volumetric dose reconstruction of single laser-driven proton bunches

在线全文

学校读者我要写书评

暂无评论

High Power Laser Science and Engineering 2024年第2期12卷 41-50页

作者： A.Corvino M.Reimold E.Beyreuther F.-E.Brack F.kroll J.Pawelke J.D.Schilz M.Schneider U.Schramm M.E.P.Umlandt k.Zeil t.Ziegler J.Metzkes-ng Helmholtz-Zentrum Dresden–Rossendorf DresdenGermany technische Universität Dresden DresdenGermany OncoRay–National Center for Radiation Research in Oncology Faculty of Medicine and University Hospital Carl Gustav CarusTUD Dresden University of TechnologyHelmholtz-Zentrum Dresden–RossendorfDresdenGermany Current affiliation:Institut Curie UniversitéPSLCNRS UMR3347OrsayFrance Current affiliation:Universitätsklinikum Freiburg FreiburgGermany

Laser plasma accelerators(LPAs)enable the generation of intense and short proton bunches on a micrometre scale,thus offering new experimental capabilities to research fields such as ultra-high dose rate radiobiology or material *** spectrally broadband,laser-accelerated proton bunches allow for tailored volumetric dose deposition in a sample via single bunches to excite or probe specific sample *** rising number of such experiments indicates a need for diagnostics providing spatially resolved characterization of dose distributions with volumes of approximately 1 cm^(3) for single proton bunches to allow for fast online *** we present the scintillator-based miniSCIDOM detector for online single-bunch tomographic reconstruction of dose distributions in volumes of up to approximately 1 cm^(3).the detector achieves a spatial resolution below 500μm and a sensitivity of 100 *** detector performance is tested at a proton therapy cyclotron and an LPA proton *** experiments’primary focus is the characterization of the scintillator’s ionization quenching behaviour.

关键词： beam monitoring detectors laser-driven proton beams scintillator-based diagnostics ultra-high dose rate

在线全文

学校读者我要写书评

暂无评论

基于ttC染色的水稻种子活力定量分析

种子 2024年第10期 135-141页

作者：乔菊香冯明春杨晓洪 Hoàng Minh tú 王世敏刘艳芳云南省农业科学院质量标准与检测技术研究所农业农村部植物新品种测试(昆明)分中心昭通学院农学与生命科学学院越南国家植物种子和农产品检测中心

为了揭示种子活力与ttC染色之间的定量关系，本研究以水稻种子CY-150为试验材料，经人工加速老化处理和ttC染色后，利用体视镜获取种子胚部纵切面的RGB图像，并用农业农村部植物新品种测试（昆明）分中心建立的图像分析软件分析图像的CI... 详细信息

为了揭示种子活力与ttC染色之间的定量关系，本研究以水稻种子CY-150为试验材料，经人工加速老化处理和ttC染色后，利用体视镜获取种子胚部纵切面的RGB图像，并用农业农村部植物新品种测试（昆明）分中心建立的图像分析软件分析图像的CIELab值，计算单位面积染色强度。结果表明，发芽率、ttC染色率和活力指数之间呈显著正相关。其中，发芽率和活力指数、发芽率和染色率、染色率和活力指数之间的相关系数分别为0.997 6、0.971 8和0.963 1。此外，CIELab值与发芽率、染色率和活力指数之间显著相关，其中，L*和a*分别呈负相关和正相关，相关系数分别为-0.974 9、-0.976 1、-0.972 1、0.973 7、0.991 5和0.967 8。利用种子活力指数与CIELab值建立了种子活力方程。通过随机选取4个水稻品种对方程进行验证，结果显示，4个品种的活力指数真实值略高于预测值。研究表明，ttC染色不仅可用于水稻种子活力快速定性分析，而且通过种胚RGB图像可以实现种子活力的定量分析，为进一步普及水稻种子活力快速检测提供参考。

关键词：水稻种子活力 ttC染色定量分析

Cardiovascular health awareness,risk perception,behavioural intention and INtERHEARt risk stratification among middle-aged adults in Malaysia

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of tropical Medicine 2024年第2期17卷 61-70页

作者： Siew-keah Lee Ang-Lim Chua Clement Heng Yew Fong Ban Hao Brian Cong Wen Ling ng Jing Feng kong Yik-Ling Chew kai Bin Liew Yang Shao M.kandiah Faculty of Medicine and Health Sciences Universiti Tunku Abdul RahmanMalaysia Faculty of Medicine Universiti Teknologi MARAMalaysia Faculty of Pharmaceutical Sciences UCSI UniversityMalaysia Faculty of Pharmacy University of CyberjayaMalaysia the First Affiliated Hospital of Hainan Medical University China

Objective:to investigate the interrelationship between cardiovascular health awareness,risk perception,behavioural intention,and INtERHEARt risk stratification in a middle-aged adult population in ***:A cross-sectional survey with convenience sampling was conducted during November 2022 and January *** completed validated questionnaires assessing cardiovascular health awareness,risk perception of cardiovascular diseases,behavioural intention towards adopting healthy habits,and INtERHEARt risk stratification score(IHRS)based on established risk factors.A total of 602 respondents were included in the final *** were analysed with independent t-test/one-way ANOVA or Mann-Whitney/kruskal-Wallis to test the differences,Pearson correlation or linear regression test to analyze the association of independent and dependent ***:there was a significant positive correlation between medical knowledge related to cardiovascular disease(CVD)and knowledge related to CVD risk prevention,risk perception,behavioural intention and IHRS(Ption).Notably,individuals with higher IHRS tended to have lower knowledge related to CVD and CVD risk prevention,risk perception,and behavioural ***,laborers,active/former smokers,individuals with lower household income and educational levels,those involved in occupations not related to the healthcare sector,and those who did not receive the CVD health brochure or are unaware of health self-assessment tools are likely to have lower levels of knowledge,risk perception,and poorer behavioural intention regarding cardiovascular health(Ptional level,smoking status,awareness about CVD poster,self-assessment tools were repeatedly significantly associated with knowledge related to CVD and CVD risk prevention,risk perception,behavioral intention and/or IHRS(Pthese findings underscore the importance of promoting car

关键词： Cardiovascular risk knowledge Risk perception Behavioural intention INtERHEARt Middle-aged Lifestyle Physical activity Psychosocial stress

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

丙烯墨水中颗粒相分散性问题研究

中国制笔 2024年第3期 30-36页

作者：潘勤敏张胜红林韶晖钱宵亮 ng Flor a t.t. 金桂英苏州大学江苏苏州215123 苏州雄鹰笔墨新材料有限公司江苏苏州215200 滑铁卢大学加拿大安大略省滑铁卢N2L 3G1

针对丙烯墨水中普遍存在的颗粒相分散问题,在对颗粒沉降原理进行简要介绍的基础上,就丙烯酸树脂的选择和改性,颗粒相的处理技术,分散剂、稳定剂、增稠剂等的研究进行了综述。

关键词：丙烯酸树脂墨水钛白粉沉降

Boosting the catalytic activity toward oxygen reduction via a heterostructure of porous iron oxide-decorated 2D NiO/ng nanosheets

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第6期93卷 669-681,I0016页

作者： kakali Maiti Matthew t.Curnan Hyung Jun kim kyeounghak kim Jeong Woo Han Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)PohangGyeongbuk 37673Republic of Korea Department of Materials Science and Engineering Research Institute of Advanced MaterialsSeoul National UniversitySeoul 08826Republic of Korea Department of Chemical Engineering Clean-Energy Research InstituteHanyang UniversitySeoul 04763Republic of Korea CSIR-Institute of Minerals and Materials technology RRL CampusAcharya ViharBhubaneswarOdisha 751013India

As a noble metal substitute,two-dimensional(2D)hierarchical nano-frame structures have attracted great interest as candidate catalysts due to their remarkable advantages-high intrinsic activity,high electron mobility,and straightforward surface ***,they may replace Pt-based catalysts in oxygen reduction reaction(ORR)***,a simple method is developed to design hierarchical nano-frame structures assembled via 2D NiO and N-doped graphene(ng)*** procedure can yield nanostructures that satisfy the criteria correlated with improved electrocatalytic performance,such as large surface area,numerous undercoordinated atoms,and high defect ***,porous ng nanosheet architectures,featuring NiO nanosheets densely coordinated with accessible holey Fe_(2)O_(3) moieties,can enhance mesoporosity and balance *** improvements can facilitate charge transport and expose formerly inaccessible reaction sites,maximizing active site density *** functional theory(DFt)calculations reveal favored O_(2) adsorption and dissociation on Fe_(2)O_(3) hybrid structures when supported by 2D NiO and ng nanomaterials,given 2D materials donated charge to Fe_(2)O_(3) active *** systematic studies reveal that synergistic contributions are responsible for enriching the catalytic activity of Fe_(2)O_(3)@NiO/ng in alkaline media-encompassing internal voids and pores,unique hierarchical support structures,and concentrated N-dopant and bimetallic atomic ***,this work expands the toolbox for designing and synthesizing highly efficient 2D/2D shelled functional nanomaterials with transition metals,endeavoring to benefit energy conversion and related ORR applications.

关键词： N-doped graphene Holey Fe_(2)O_(3)nanocrystals NiO nanosheets High catalytic performance ORR

Second-order optimality conditions f or minimizing a maxfunction

在线全文

学校读者我要写书评

暂无评论

Science China Mathematics 2000年第7期43卷 722-733页

作者：黄力人 k.F.ng Department of Mathematics South China Normal University Guangzhou 510631 China Department of Mathematics The Chinese University of Hong KongHong KongChina Correspondence should be addressed to K.F.Ng

We study Chaney's and Ben-tal-Zowe's second-order directional derivatives with applications in minimization problem for max-functions of the formh(x): = max {f(x, τ); τ ∈t},where t is a compact metricspace. We impr... 详细信息

关键词： max-f unction sup-type function second-order optimality condition nonsmooth optimization.