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Impact of Pollutant Concentration and Particle Deposition on the Radiative Flow of Casson-Micropolar Fluid between Parallel Plates

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 665-690页

作者： Ghaliah Alhamzi Badr Saad t.Alkahtani Ravi Shanker Dubey Vinutha Kalleshachar Neelima Nizampatnam Department of Mathematics and Statistics College of ScienceImam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11564Saudi Arabia Department of Mathematics College of ScienceKing Saud UniversityRiyadh11989Saudi Arabia Department of Mathematics Amity School of Applied SciencesAmity University RajasthanJaipur302002RajasthanIndia Department of Studies in Mathematics Davangere UniversityDavangere577002India Department of Electronics and Communication Engineering Amrita School of EngineeringAmrita Vishwa VidyapeethamBengaluru560035India

Assessing the behaviour and concentration of waste pollutants deposited between two parallel plates is essential for effective environmental *** the effectiveness of treatment methods in reducing pollution scales is made easier by analysing waste discharge *** waste discharge concentration analysis is useful for assessing how effectively wastewater treatment techniques reduce pollution *** study aims to explore the Casson micropolar fluid flow through two parallel plates with the influence of pollutant concentration and thermophoretic particle *** explore the mass and heat transport features,thermophoretic particle deposition and thermal radiation are *** governing equations are transformed into ordinary differential equations with the help of suitable similarity *** Runge-Kutta-Fehlberg’s fourthfifth order technique and shooting procedure are used to solve the reduced set of equations and boundary *** integration of a neural network model based on the Levenberg-Marquardt algorithm serves to improve the accuracy of predictions and optimize the analysis of *** outcomes are displayed to analyze the characteristics of the relevant dimensionless parameters in the current *** reveal that concentration upsurges as the micropolar parameter *** concentration reduces with an upsurge in the thermophoretic *** upsurge in the external pollutant source variation and the local pollutant external source parameters enhances mass *** surface drag force declines for improved values of porosity and micropolar parameters.

关键词： Micropolar fluid thermal radiation porous medium thermophoretic particle deposition waste discharge concentration

Advancing 5G Network Applications Lifecycle Security:An ML-Driven Approach

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Computer Modeling in Engineering & Sciences 2024年第11期141卷 1447-1471页

作者： Ana hermosilla Jorge Gallego-Madrid Pedro Martinez-Julia Jordi Ortiz Ved P.Kafle Antonio Skarmeta Information and Communications Engineering Department University of MurciaMurcia30100Spain Research&Development Department Odin Solutions S.L.Murcia30007Spain Network Architecture Laboratory Network Research InstituteNational Institute of Information and CommunicationsTokyo184-8795Japan Engineering and Applied techniques Department University Center of Defense at the Spanish Air Force AcademyMurcia30729Spain

As 5th Generation(5G)and Beyond 5G(B5G)networks become increasingly prevalent,ensuring not only networksecurity but also the security and reliability of the applications,the so-called network applications,becomesof paramount *** paper introduces a novel integrated model architecture,combining a networkapplication validation framework with an AI-driven reactive system to enhance security in *** proposedmodel leverages machine learning(ML)and artificial intelligence(AI)to dynamically monitor and respond tosecurity threats,effectively mitigating potential risks before they impact the network *** dualapproach not only validates the functionality and performance of network applications before their real deploymentbut also enhances the network’s ability to adapt and respond to threats as they *** implementation ofthis model,in the shape of an architecture deployed in two distinct sites,demonstrates its practical viability *** application validation with proactive threat detection and response,the proposed modeladdresses critical security challenges unique to 5G *** paper details the model,architecture’sdesign,implementation,and evaluation of this solution,illustrating its potential to improve network securitymanagement in 5G environments *** findings highlight the architecture’s capability to ensure boththe operational integrity of network applications and the security of the underlying infrastructure,presenting asignificant advancement in network security.

关键词： Network application network function virtualization machine learning security 5G

Fecal microbiota transplantation in allergic diseases

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World Journal of Methodology 2025年第2期15卷 83-91页

作者： Ece tüsüzÖnata ÖnerÖzdemir Division of Pediatric Allergy and Immunology Medical FacultySakarya UniversityAdapazarı54100SakaryaTürkiye

Microorganisms such as bacteria,fungi,viruses,parasites living in the human intestine constitute the human intestinal *** refers to composi-tional and quantitative changes that negatively affect healthy gut *** recent years,with the demonstration that many diseases are associated with dysbiosis,treatment strategies targeting the correction of dysbiosis in the treat-ment of these diseases have begun to be *** microbiota trans-plantation(FMt)is the process of transferring faeces from a healthy donor to another recipient in order to restore the gut microbiota and provide a therapeutic *** studies have gained popularity after probiotic,prebiotic,symbiotic studies in the treatment of dysbiosis and related *** has emerged as a potential new therapy in the treatment of allergic diseases as it is associated with the maintenance of intestinal microbiota and immunological balance(t helper 1/t helper 2 cells)and thus suppression of allergic *** this article,the definition,application,safety and use of FMt in allergic diseases will be discussed with current data.

关键词： Microbiota Dysbiosis Faecal microbiota transplantation Allergic diseases

On a Dual to the Properties of Hurwitz Polynomials I

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American Journal of Computational Mathematics 2021年第1期11卷 31-41页

作者： Gastón Vergara-hermosilla Université de Bordeaux Talence France

In this work we develop necessary and sufficient conditions for describing the family of anti-Hurwitz polynomials, introduced by Vergara-hermosilla et al. in [1]. Specifically, we studied a dual version of the theorem of Routh-Hurwitz and present explicit criteria for polynomials of low order and derivatives. Another contribution of this work is establishing a dual version of the Hermite-Biehler theorem. to this aim, we give extensions of the boundary crossing theorems and a zero exclusion principle for anti-Hurwitz polynomials.

关键词： Hurwitz Polynomials Anti-Hurwitz Polynomials Hermite-Biehler theo-rem Exclusion Principle

Neutrophil extracellular traps in the intestinal mucosa of Eimeria-infected animals

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Asian Pacific Journal of tropical Biomedicine 2016年第4期6卷 301-307页

作者： tamara Munoz-Caro Liliana Machado Ribeiro da Silva Zaida Renteria-Solis Anja taubert Carlos hermosilla Institute of Parasitology Justus Liebig University Giessen

Objective:to investigate the presence of neutrophil extracellular traps(NEts) in vivo by analysing intestinal sections from experimentally Eimeria bovis-and naturally Eimeria arloingi-infected ***:Intestinal samples of Eimeria arloingi-and Eimeria bovis-infected animals were analysed by using immunohistochemical and fluorescence approach by using monoclonal ***:Classical NEt components were confirmed by co-localization of extracellular DNA being decorated with neutrophil elastase and histones in Eimeria-infected tissue ***,extrusion of NEts was exclusively detected in intestinal polymorphonuclear neutrophils infiltrating Eimeria-infected *** vivo NEts were either found in close proximity or in direct contact to different Eimeria stages suggesting a stage-independent *** were also found within the gut lumen driven by polymorphonuclear neutrophils that were contacting released ***:We postulate that NEts might play an important role in innate defence reactions in coccidiosis therefore significantly altering the outcome of infection.

关键词： Eimeria bovis Eimeria arloingi Neutrophil extracellular traps Apicomplexa Coccidiosis

Mass data processing of time series Landsat imagery:pixels to data products for forest monitoring

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International Journal of Digital Earth 2016年第11期9卷 1035-1054页

作者： txomin hermosilla Michael A.Wulder Joanne C.White Nicholas C.Coops Geordie W.Hobart Lorraine B.Campbella Integrated Remote Sensing Studio Department of Forest Resources ManagementUniversity of British ColumbiaVancouverBCCanada Canadian Forest Service(Pacific Forestry Centre) Natural Resources CanadaVictoriaBCCanada

Free and open access to the Landsat archive has enabled the implementation of national and global terrestrial monitoring ***,we summarize a project characterizing the change history of Canada’s forested ecosystems with a time series of data representing *** the Composite2Change approach,we applied spectral trend analysis to annual best-available-pixel(BAP)surface reflectance image composites produced from Landsat tM and EtM+imagery.A total of 73,544 images were used to produce 29 annual image composites,generating∼400 tB of interim data products and resulting in∼25 tB of annual gap-free reflectance composites and change *** average,10%of pixels in the annual BAP composites were missing data,with 86%of pixels having data gaps in two consecutive years or *** detection overall accuracy was 89%.Change attribution overall accuracy was 92%,with higher accuracy for standreplacing wildfire and *** were assigned to the correct year with an accuracy of 89%.Outcomes of this project provide baseline information and nationally consistent data source to quantify and characterize changes in forested *** methods applied and lessons learned build confidence in the products generated and empower others to develop or refine similar satellite-based monitoring projects.

关键词： Remote sensing big data forest change monitoring image processing

Use of subcutaneous tocilizumab to prepare intravenous solutions for COVID-19 emergency shortage:Comparative analytical study of physicochemical quality attributes

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Journal of Pharmaceutical Analysis 2020年第6期10卷 532-545页

作者： Natalia Navas Jesús hermosilla Anabel torrente-Lopez Jose Hernandez-Jimenez Jose Cabeza Raquel Perez-Roblesa Antonio Salmeron-García Department of Analytical Chemistry Science Faculty/Biomedical Research Institute ibs.GranadaUniversity of GranadaGranadaE-18071Spain UGC Farmacia Hospitalaria Biomedical Research Institute ibs.Granada.Hospital Universitario San Cecilio de GranadaGranadaE-18012Spain

COVID-19,a disease caused by the novel coronavirus SARS-Co V-2,has produced a serious emergency for global public health,placing enormous stress on national health systems in many *** studies suggest that cytokine storms(interleukins)may play an important role in severe cases of *** key inflammatory factors in cytokine release syndrome(CRS)could therefore be of great value in reducing the mortality ***(tCZ)in its intravenous(IV)form of administration-Ro Actemra?20 mg/m L(Roche)-is indicated for treatment of severe CRS *** investigations have concluded that inhibition of IL-6 with tCZ appears to be efficacious and safe,with several ongoing clinical *** has led to a huge increase in demand for IV tCZ for treating severe COVID-19 patients in hospitals,which has resulted in drug ***,we present a comparability study assessing the main critical physicochemical attributes of tCZ solutions used for infusion,at 6 mg/m L and 4 mg/m L,prepared from Ro Actemra?20 mg/m L(IV form)and from Ro Actemra?162 mg(0.9 m L solution pre-filled syringe,subcutaneous(SC)form),to evaluate the use of the latter for preparing clinical solutions required for IV administration,so that in a situation of shortage of the IV medicine,the SC form could be used to prepare the solutions for IV delivery of *** is important to remember that during the current pandemic all the medicines are used off-label,since none of them has yet been approved for the treatment of COVID-19.

关键词： COVID-19 tocilizumab Critical quality attributes IV and SC medicines

Surgical site soft tissue thickness as a predictor of complications following arthroplasty

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World Journal of Methodology 2025年第2期15卷 62-73页

作者： Kevin A Wu Faheem Pottayil Crystal Jing Ankit Choudhury Albert t Anastasio Department of Orthopaedic Surgery Duke University HospitalDurhamNC 27710United States Department of Orthopaedic Surgery Medical College of Georgia at Augusta UniversityAugustaGA 30912United States Department of Orthopaedic Surgery Medical College of WisconsinMilwaukeeWI 53226United States

Appreciation of soft-tissue thickness(Stt)at surgical sites is an increasingly recognized aspect of arthroplasty procedures as it may potentially impacting postoperative *** research has focused on the predictive value of preoperative Stt measurements for complications following various forms of arthroplasty,particularly infections,across procedures such as total knee,hip,shoulder,and ankle *** studies have indicated that increased Stt is associated with a higher risk of complications,including infection and wound healing *** assessment of Stt before surgery could play a crucial role in identifying patients at a higher risk of complications and may be instru-mental in guiding preoperative planning to optimize outcomes in arthroplasty *** measurement techniques and further research are essential to enhance the reliability and clinical utility of Stt assessment for arthro-plasty surgery.

关键词： Soft-tissue thickness Arthroplasty Surgical complications total knee arthroplasty total hip arthroplasty total shoulder arthroplasty total ankle arthroplasty Preoperative assessment Wound healing Infection risk

Immunohistochemical expression of matrix metalloproteinase-9 and 13 in oral squamous cell carcinoma and their role in predicting lymph node metastasis

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World Journal of Methodology 2025年第2期15卷 108-116页

作者： Bhari Sharanesha Manjunatha Keshav t Handge Vandana Sandeep Shah Yasser Eid Al-thobaiti Deepak Gowda Sadashivappa Pateel Department of Basic Oral Medicine and Allied Dental Sciences Taif UniversityAt`Taif 26571MakkahSaudi Arabia Department of Oral and Maxillofacial Pathology Dr.Vasantrao Pawar Medical CollegeHospital and Research CentreNashik 423101MaharashtraIndia Department of Oral Pathology and Microbiology KM Shah Dental College and HospitalSumandeep VidyapeethVadodara 391760GujaratIndia Department of Oral and Maxillofacial Surgery and Diagnostic Sciences Faculty of DentistryTaif UniversityAl-Haweiah 26571 MakkahSaudi Arabia Department of Oral Pathology and Microbiology Faculty of DentistryMAHSA UniversitySelangor 42610Malaysia

BACKGROUND One of the main characteristics of oral squamous cell carcinoma(OSCC)is that it metastasizes to cervical lymph nodes frequently with a high degree of local invasiveness.A primary feature of malignant tumors is their penetration of neighboring tissues,such as lymphatic and blood arteries,due to the tumor cells'capacity to break down the extracellular matrix(ECM).Matrix metalloproteinases(MMPs)constitute a family of proteolytic enzymes that facilitate tissue remo-deling and the degradation of the ***-9 and MMP-13 belong to the group of extracellular matrix degrading enzymes and their expression has been studied in OSCC because of their specific ***-13,a collagenase family member,is thought to play an essential role in the MMP activation cascade by breaking down the fibrillar collagens,whereas MMP-9 is thought to accelerate the growth of *** MMP-13 expression has been associated with tumor behavior and patient prognosis in a number of malignant *** authors wish to thank Jadhav KB for his valuable opinion during the preparation of the manuscript.

关键词： Matrix metalloproteinases Oral squamous cell carcinoma tumor staging Immunohistochemistry Invasion Lymph node metastasis tNM stage