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Hepatocellular Carcinoma Incidence and Mortality in the USA by Sex, Age, and Race: A Nationwide Analysis of two decades

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Journal of Clinical and translational Hepatology 2024年第2期12卷 172-181页

作者： Yazan Abboud Mohamed Ismail Hamza Khan Esli Medina-Morales Saqr Alsakarneh Fouad Jaber Nikolaos t.Pyrsopoulos department of Internal Medicine Rutgers New Jersey Medical SchoolNewarkNJUSA department of Internal Medicine University of Missouri-Kansas CityKansas CityMOUSA division of Gastroenterology and Hepatology Rutgers New Jersey Medical SchoolNewarkNJUSA

Background and Aims:While the incidence rates of hepa-tocellular carcinoma(HCC)are increasing,there are limited comprehensive data on demographic-specific incidence and mortality trends in the *** aimed to evaluate recent trends in HCC incidence and mortality among different de-mographic groups in the ***:Age-adjusted HCC incidence rates were calculated from the Centers for disease Control's United States Cancer Statistics database,which combines incidence data on newly diagnosed cancer cases and covers approximately 98%of the population in the ***,age-adjusted HCC mortality rates were obtained from the Centers for disease Control's National Center for Health Statistics database,which offers comprehensive Cov-erage spanning nearly 100%of deaths attributed to HCC in the *** were stratified by sex,age(older[≥55 years]and younger[dults),race and ethnicity(Non-Hispanic White,Non-Hispanic Black,Hispanic,Non-Hispanic Asian/Pacific Islander,and Non-Hispanic American Indian/Alaska Native),and tumor stage at diagnosis(early and late).Annual and average annual percentage change(AAPC)were calculated using joinpoint regression.A sex-specific pairwise comparison was ***:Between 2001 and 2020,there were 467,346 patients diagnosed with HCC(26.0%women),with increasing incidence in both sexes without significant difference(p=0.65).In younger adults(78,169 patients),the incidence decreased in men but not in women(AAPC difference=-2.39,p=0.002).this was seen in various racial and ethnic groups,mostly driven by early-stage tumors(AAPC difference=-2.65,p=0.02).there were 329,973 deaths attributed to HCC between 2000 and 2020(28.4%women).In younger adults(43,093 deaths),mortal-ity decreased in men at a greater rate than in women(AAPC difference=1.61,p=0.007).this was seen in various racial and ethnic groups,most notably in non-Hispanic American Indian/Alaska Natives(AAPC difference=-4.51,p=0.01).Conclusions:Nationwide USA data,coveri

关键词： Liver cancer Hepatocellular carcinoma Incidence Mortality Epidemiology Health disparity

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Comparative Orotomy of the Archean Superior, North China, and Phanerozoic Altaid Orogenic Systems Architecture

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Acta Geologica Sinica(English Edition) 2024年第S1期 33-35页

作者： t.M.KUSKY A.M.C.?ENG?R Center for Global tectonics School of Earth Sciences and State Key Laboratory for Geological Processes and Mineral Resources China University of Geosciences Eurasia Institute of Earth Sciences Istanbul Technical University department of Geology Faculty of Mines Istanbul Technical University

Geological maps encode vast amounts of data about rock types, ages, chemistry, orogenic architecture and deep-time history or different tectonic units, yet these are often difficult to extract because of the way different geologists portray their results at various scales. to understand orogenesis in 4d, it is essential to uniformly integrate map data, together with geophysical data and deep geochemical mapping(Wang et al., 2023).

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1950~2020年中国沿海海平面上升

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中国科学：地球科学 2024年第3期54卷 821-829页

作者：穆大鹏徐天河闫昊明山东大学空间科学研究院威海264209 中国科学院精密测量科学与技术创新研究院武汉430071 Institute of Marine and Antarctic Science University of TasmaniaHobartTasmania 7004Australia

验潮站能够观测海平面长期变化,并被用于重构全球平均海平面上升.然而,中国沿海区域的海平面长期变化尚未被揭示.本文构建了一种数据同化方法,可以重构中国沿海地区1950年以来的海平面上升.该方法以全球验潮站观测为约束,同时利用气候... 详细信息

验潮站能够观测海平面长期变化,并被用于重构全球平均海平面上升.然而,中国沿海区域的海平面长期变化尚未被揭示.本文构建了一种数据同化方法,可以重构中国沿海地区1950年以来的海平面上升.该方法以全球验潮站观测为约束,同时利用气候模式输出的动态海平面和陆地水质量迁移导致的海平面指纹效应.本文重构的全球平均海平面上升与之前的研究结果接近.中国沿海地区20个验潮站的重构结果显示,1950~2020年中国沿海平均海平面上升速率为(1.95±0.33)mm a^(-1),高于同时期的全球平均上升速率(1.71±0.17)mm a^(-1).此外,本文还发现,中国沿海平均海平面上升速率在1980年以后是之前速率的3倍以上,速率从1950~1980年的(0.84±0.28)mm a^(-1)增加到1980~2020年的(3.12±0.21)mm a^(-1).该发现说明中国沿海海平面存在显著的加速上升,这些结果增进了对中国沿海海平面长期变化的理解与认识.

关键词：海平面上升中国沿海验潮站数据同化

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Rao Algorithms-Based Structure Optimization for Heterogeneous Wireless Sensor Networks

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Computers, Materials & Continua 2024年第1期78卷 873-897页

作者： Shereen K.Refaay Samia A.Ali Moumen t.El-Melegy Louai A.Maghrabi Hamdy H.El-Sayed Faculty of Computers and Artificial Intelligence Sohag UniversitySohag82524Egypt Faculty of Engineering Assiut UniversityAssiut711745Egypt College of Engineering University of Business and TechnologyJeddah23411Saudi Arabia

the structural optimization of wireless sensor networks is a critical issue because it impacts energy consumption and hence the network’s *** studies have been conducted for homogeneous networks,but few have been performed for heterogeneouswireless sensor *** paper utilizes Rao algorithms to optimize the structure of heterogeneous wireless sensor networks according to node locations and their initial *** proposed algorithms lack algorithm-specific parameters and metaphorical *** proposed algorithms examine the search space based on the relations of the population with the best,worst,and randomly assigned *** proposed algorithms can be evaluated using any routing protocol,however,we have chosen the well-known routing protocols in the literature:Low Energy Adaptive Clustering Hierarchy(LEACH),Power-Efficient Gathering in Sensor Information Systems(PEAGSIS),Partitioned-based Energy-efficient LEACH(PE-LEACH),and the Power-Efficient Gathering in Sensor Information Systems Neural Network(PEAGSIS-NN)recent routing *** compare our optimized method with the Jaya,the Particle Swarm Optimization-based Energy Efficient Clustering(PSO-EEC)protocol,and the hybrid Harmony Search Algorithm and PSO(HSA-PSO)*** efficiencies of our proposed algorithms are evaluated by conducting experiments in terms of the network lifetime(first dead node,half dead nodes,and last dead node),energy consumption,packets to cluster head,and packets to the base *** experimental results were compared with those obtained using the Jaya optimization *** proposed algorithms exhibited the best *** proposed approach successfully prolongs the network lifetime by 71% for the PEAGSIS protocol,51% for the LEACH protocol,10% for the PE-LEACH protocol,and 73% for the PEGSIS-NN protocol;Moreover,it enhances other criteria such as energy conservation,fitness convergence,packets to cluster head,and packets to the base sta

关键词： Wireless sensor networks Rao algorithms optimization LEACH PEAGSIS

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Standard Model Fermion Masses and Charges from Holographic Analysis

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Journal of Modern Physics 2024年第6期15卷 796-803页

作者： t. R. Mongan Sausalito CA USA

the Standard Model of particle physics involves twelve fundamental fermions, treated as point particles, in four charge states. However, the Standard Model does not explain why only three fermions are in each charge state or account for neutrino mass. this holographic analysis treats charged Standard Model fermions as spheres with mass 0.187 g/cm2 times their surface area, using the proportionality constant in the holographic relation between mass of the observable universe and event horizon radius. the analysis requires three Standard Model fermions per charge state and relates up quark and down quark masses to electron mass. Holographic analysis specifies electron mass, to six significant figures, in terms of fundamental constants α,ℏ,G,Λ and Ω Λ . treating neutrinos as spheres and equating electron neutrino energy density with cosmic vacuum energy density predicts neutrino masses consistent with experiment.

关键词： Electron Mass Up Quark Mass down Quark Mass Neutrino Masses

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Porphyrins,phthalocyanines,and related covalent-organic frameworks in the photochemical and electrochemical water splitting:A review

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Particuology 2024年第7期90卷 236-265页

作者： Oxana V.Kharissova Yolanda Peña Méndez Boris I.Kharisov Aleksandr LNikolaev Edith Luévano-Hipólito Lucy t.González Universidad Autónoma de Nuevo León Ave.Universidad s/nSan Nicolás de los GarzaNuevo León66455Mexico department of Chemistry Moscow State UniversityVorobievy HillsMoscowRussia CONACYt-Universidad Autónoma de Nuevo León Facultad de Ingeniería Civil-Departamento de Ecomateriales y EnergíaCd.UniversitariaC.P.66455San Nicolás de los GarzaNLMexico tecnologico de Monterrey Escuela de Ingeniería y CienciasMonterreyNuevo León 64890Mexico tecnologico de Monterrey Centro del AguaMonterreyNuevo León 64890Mexico

In this review,the possibilities of photochemical and electrochemical water splitting(WS)using porphyrins,phthalocyanines,related macrocycles,and their metal complexes are *** efforts are being carried out in order to develop novel and cheap methods for water decomposition to generate inexhaustible greener energy sources(molecular hydrogen)instead of oil and *** processes of WS in heterogeneous and homogeneous media require novel photo-and electrocatalysts,in particular those on macrocycle basis.A high WS efficiency has been observed for porphyrins and phthalocyanines,showing their suitability both for HER and OER processes are available using these relative compounds for WS *** can be used in photocatalytic and electrocatalytic WS processes both in their free forms or as metal porphyrins/porphyrinates,mainly loaded on various inorganic materials,such as Au NPs,C_(3)N_(4),GaP,KtaO_(3),GaP,and so on,as part of porphyrin-containing polymers or on electrode surface as modifying coatings,being sometimes better than commercial catalysts,such as Pt/*** H2 evolution can be considerably depended on the shape of porphyrin particles;in particular,porphyrin nanowires can yield up to 20 times more H2 than its *** certain cases,both HER and OER can be driven in the same electrolyte using metal *** capacity of metal porphyrins to generate ROS(in particular,singlet oxygen 1O_(2))under ultrasonic treatment is known and can be successfully used for H_(2)O_(2) and O_(2) *** can be used in similar processes in free form or as composites with inorganic or organic counterparts,being immobilized on nanocarbons,metal oxides and salts,or simply dissolved in water acting in a homogeneous *** additional use of ultrasound can lead to better results due to the synergistic effect of the sonochemical treatment and ***-organic frameworks are also applied for WS purposes and are mainly based

关键词： Porphyrins Phthalocyanines COFs Water splitting Photocatalysis Electrocatalysis

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development of a Proof-of-Concept Multi-Method Computer Simulation to Support Rural Healthcare disaster Preparedness Planning

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International Journal of disaster Risk Science 2024年第3期15卷 346-358页

作者： thomas A.Berg Kristina W.Kintziger Julie Suzuki Crumly Scott A.Lawson Carole R.Myers tracey t.Stansberry College of Nursing University of Tennessee Knoxville department of Environmental Agricultural and Occupational Health University of Nebraska Medical Center Public Health and Healthcare Oak Ridge Associated Universities

due to a lack of resources, rural communities often face challenges when planning catastrophic events. this project involved applying systems thinking and model-based systems engineering to develop a proof-of-concept, multi-method computer simulation and then determining whether the simulation could be used to assess the efficacy of disaster planning approaches on health outcomes in rural communities, as a function of primary healthcare. the project focus was a rural or non-urban healthcare system experiencing a natural hazard. Both system dynamics and discrete event models were incorporated to represent subsystem operations, crucial disaster responses, as well as three key response systems: public health, emergency management, and healthcare. the subsystem models included several components: policies/procedures, communications,resources, exercises/drills/training, healthcare space and staff, and the flow of affected people into and through the *** combined simulation can serve as a first step to a more comprehensive approach to helping rural communities achieve more efficient and effective healthcare planning for disaster responses.

关键词： Computer simulation disaster preparedness Model-based systems engineering Rural healthcare System dynamics model Systems thinking

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Chromomagnetic dipole moments of light quarks in the bestest little Higgs model

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Chinese Physics C 2024年第10期48卷 125-136页

作者： t.Cisneros-Pérez E.Cruz-Albaro A.Y.Ojeda-Castañeda S.E.Solís-Núñez Unidad Académica de Ciencias Químicas Universidad Autónoma de ZacatecasApartado Postal C-58598060 ZacatecasMexico Facultad de Física Universidad Autónoma de ZacatecasApartado Postal C-58098060 ZacatecasMexico

In this study,we investigated the anomalous Chromomagnetic dipole Moment(CMdM),denoted as μ_(q)^(BLHM),of light quarks q=(u,c,d,s,b) within the framework of the Bestest Little Higgs Model(BLHM)as an extension of the Standard Model(SM).Our investigation encompassed novel interactions among the light quarks,heavy quark B,and heavy bosons (W'^(±),H^(±),φ^(±),η^(±))incorporating the extended Cabibbo-Kobayashi-Maskawa(CKM)matrix characteristic of the *** thoroughly explored the permissible parameter space,yielding a spectrum of CMdM values ranging from 10^(-10) to 10^(-3).

关键词： beyond standard model flavor physics chromomagnetic dipole light quarks

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data-driven analysis of chemicals,proteins and pathways associated with peanut allergy:from molecular networking to biological interpretation

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Food Science and Human Wellness 2024年第3期13卷 1322-1335页

作者： Emmanuel Kemmler Julian Braun Florent Fauchère Sabine dölle-Bierke Kirsten Beyer Robert Preissner Margitta Worm Priyanka Banerjee Institute for Physiology Charité-University Medicine BerlinBerlin 10115Germany Member of the KFO339 FOOD@Berlin 10115Germany Si-M/“der Simulierte Mensch”a science framework of technische Universität Berlin and Charité-Universitätsmedizin Berlin Berlin 10115Germany Charité-Universitätsmedizin Berlin corporate member of Freie Universität BerlinHumboldt-Universität zu Berlinand Berlin Institute of HealthBerlin 10115Germany division of Allergy and Immunology Department of DermatologyVenerology and AllergyCharité-Universitätsmedizin Berlincorporate member of Freie Universität Berlin and Humboldt-Universität zu BerlinBerlin 10115Germany Pediatrics Campus VirchowCharité-University Medicine BerlinBerlin 10115Germany

Peanut allergy is majorly related to severe food induced allergic *** food including cow's milk,hen's eggs,soy,wheat,peanuts,tree nuts(walnuts,hazelnuts,almonds,cashews,pecans and pistachios),fish and shellfish are responsible for more than 90%of food ***,we provide promising insights using a large-scale data-driven analysis,comparing the mechanistic feature and biological relevance of different ingredients presents in peanuts,tree nuts(walnuts,almonds,cashews,pecans and pistachios)and ***,we have analysed the chemical compositions of peanuts in different processed form raw,boiled and *** the data-driven approach we are able to generate new hypotheses to explain why nuclear receptors like the peroxisome proliferator-activated receptors(PPARs)and its isoform and their interaction with dietary lipids may have significant effect on allergic *** results obtained from this study will direct future experimeantal and clinical studies to understand the role of dietary lipids and PPARisoforms to exert pro-inflammatory or anti-inflammatory functions on cells of the innate immunity and influence antigen presentation to the cells of the adaptive immunity.

关键词： Allergy informatics Knowledge-graph data analysis Food allergy Peroxisome proliferator-activated receptors Fatty acids

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Optimization of the Use of Spherical targets for Point Cloud Registration Using Monte Carlo Simulation

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Journal of Geodesy and Geoinformation Science 2024年第2期7卷 18-36页

作者： CHAN ting On XIAO Hang XIA Linyuan LICHtI derek d LI Ming Ho dU Guoming School of Geography and Planning Sun Yat-sen UniversityGuangzhou 510275China Guangdong Provincial Key Laboratory of Urbanization and Geo-Simulation Sun Yat-sen UniversityGuangzhou 510275China Guangdong Provincial Engineering Research Center for Public Security and disasters Sun Yat-sen UniversityGuangzhou 510275China department of Geomatics Engineering Schulich School of EngineeringUniversity of CalgaryCalgary AB T2N 1N4Canada

Registrations based on the manual placement of spherical targets are still being employed by many professionals in the ***,the placement of those targets usually relies solely on personal experience without scientific evidence supported by numerical *** paper presents a comprehensive investigation,based on Monte Carlo simulation,into determining the optimal number and positions for efficient target placement in typical scenes consisting of a pair of *** demonstrates new check-up statistical rules and geometrical constraints that can effectively extract and analyze massive simulations of unregistered point clouds and their corresponding *** than 6×10^(7) sets of the registrations were simulated,whereas more than IOO registrations with real data were used to verify the results of *** results indicated that using five spherical targets is the best choice for the registration of a large typical registration site consisting of two vertical facades and a ground,when there is only a box set of spherical targets *** a result,the users can avoid placing extra targets to achieve insignificant improvements in registration *** results also suggest that the higher registration accuracy can be obtained when the ratio between the facade-to-target distance and target-to-scanner distance is approximately 3:***,the targets should be placed closer to the scanner rather than in the middle between the facades and the scanner,contradicting to the traditional thought. Besides,the results reveal that the accuracy can be increased by setting the largest projected triangular area of the targets to be large.

关键词： point cloud registration Monte Carlo simulation optimalization spherical target

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