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Metrology for sub-Rayleigh-length target positioning in~10^(22)W/cm^(2)laser-plasma experiments

High Power Laser Science and Engineering 2024年第3期12卷 90-105页

作者： E.A.Vishnyakov A.Sagisaka K.Ogura t.Zh.Esirkepov B.Gonzalez-Izquierdo c.D.Armstrong t.A.Pikuz S.A.Pikuz W.Yan t.M.Jeong S.Singh P.Hadjisolomou O.Finke G.M.Grittani M.Nevrkla c.M.Lazzarini A.Velyhan t.Hayakawa Y.Fukuda J.K.Koga M.Ishino K.Kondo Y.Miyasaka A.Kon M.Nishikino Y.V.Nosach D.Khikhlukha I.P.tsygvintsev D.Kumar J.Nejdl D.Margarone P.V.Sasorov S.Weber M.Kando H.Kiriyama Y.Kato G.Korn K.Kondo S.V.Bulanov t.Kawachi A.S.Pirozhkov ELI Beamlines Facility The Extreme Light Infrastructure ERICDolníBrežanyCzech Republic Kansai Institute for Photon Science(KPSI) QSTKyotoJapan central Laser Facility Rutherford Appleton LaboratorySTFCHarwell OxfordDidcotUK Institute for Open and transdisciplinary Research Initiatives Osaka UniversityOsakaJapan HB11 Energy Holdings FreshwaterAustralia Key Laboratory for Laser Plasmas(Ministry of Education) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghaiChina collaborative Innovation center of IFSA Shanghai Jiao Tong UniversityShanghaiChina Institute of Plasma Physics AScR PragueCzech Republic FZU-Institute of Physics AScR PragueCzech Republic czech technical University in Prague FNSPEPragueCzech Republic Institute of Laser Engineering Osaka UniversityOsakaJapan Institute of Physics National Academy of Sciences of UkraineKyivUkraine IStEQ AR YerevanArmenia

tight focusing with very small f-numbers is necessary to achieve the highest at-focus ***,tight focusing imposes strong demands on precise target positioning in-focus to achieve the highest on-target irradiance We describe several near-infrared,visible,ultraviolet and soft and hard X-ray diagnostics employed in a~10^(22)W/cm^(2)laser±plasma *** used nearly 10 J total energy femtosecond laser pulses focused into an approximately1.3-μm focal spot on 5±20μm thick stainless-steel *** discuss the applicability of these diagnostics to determine the best in-focus target position with approximately 5μm accuracy(i.e.,around half of the short Rayleigh length)and show that several diagnostics(in particular,3ωreflection and on-axis hard X-rays)can ensure this *** demonstrated target positioning within several micrometers from the focus,ensuring over 80%of the ideal peak laser intensity *** approach is relatively fast(it requires 10±20 laser shots)and does not rely on the coincidence of low-power and high-power focal planes.

关键词： laser-plasma interaction precise target positioning spectroscopy ultra-high intensity X-rays

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comparison of fungal vs bacterial infections in the medical intensive liver unit:cause or corollary for high mortality?

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World Journal of Hepatology 2024年第3期16卷 379-392页

作者： Sarah Khan Hanna Hong Stephanie Bass Yifan Wang Xiao-Feng Wang Omar t Sims christine E Koval Aanchal Kapoor christina c Lindenmeyer Department of Internal Medicine Cleveland ClinicClevelandOH 44195United States cleveland clinic Lerner college of Medicine Cleveland ClinicClevelandOH 44195United States Department of Pharmacy Cleveland ClinicClevelandOH 44195United States Department of Quantitative Health Sciences/Biostatistics Section Cleveland ClinicClevelandOH 44195United States Department of Gastroenterology Hepatology and NutritionCleveland ClinicClevelandOH 44195United States Department of Infectious Disease Cleveland ClinicClevelandOH 44195United States Department of critical care Medicine Cleveland ClinicClevelandOH 44195United States

BAcKGROUND Due to development of an immune-dysregulated phenotype,advanced liver disease in all forms predisposes patients to sepsis acquisition,including by opportunistic pathogens such as *** data exists on fungal infection within a medical intensive liver unit(MILU),particularly in relation to acute on chronic liver *** to investigate the impact of fungal infections among critically ill patients with advanced liver disease,and compare outcomes to those of patients with bacterial *** From our prospective registry of MILU patients from 2018-2022,we included 27 patients with culture-positive fungal infections and 183 with bacterial *** compared outcomes between patients admitted to the MILU with fungal infections to bacterial *** was extracted through chart *** All fungal infections were due to candida species,and were most frequently blood *** among patients with fungal infections was significantly worse relative to the bacterial cohort(93%vs 52%,Pthe majority of the fungal cohort developed grade 2 or 3 acute on chronic liver failure(AcLF)(90%vs 64%,P=0.02).Patients in the fungal cohort had increased use of vasopressors(96%vs 70%,P=0.04),mechanical ventilation(96%vs 65%,Pto acute kidney injury(78%vs 52%,P=0.014).On MILU admission,the fungal cohort had significantly higher Acute Physiology and chronic Health Evaluation(108 vs 91,P=0.003),Acute Physiology Score(86 vs 65,P=0.003),and Model for End-Stage Liver Disease-Sodium scores(86 vs 65,P=0.041).there was no significant difference in the rate of central line use preceding culture(52%vs 40%,P=0.2).Patients with fungal infection had higher rate of transplant hold placement,and lower rates of transplant;however,differences did not achieve statistical *** Mortality was worse among patients with fungal infections,likely attributable to severe AcLF *** studies examinin

关键词： Fungal Infection Sepsis Acute on chronic liver failure Intensive care

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the Soft X-ray Imager(SXI)on the SMILE Mission

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Earth and Planetary Physics 2024年第1期8卷 5-14页

作者： S.Sembay A.L.Alme D.Agnolon t.Arnold A.Beardmore A.Belén Balado Margeli c.Bicknell c.Bouldin G.Branduardi-Raymont t.crawford J.P.Breuer t.Buggey G.Butcher R.canchal J.A.carter A.cheney Y.collado-Vega H.connor t.crawford N.Eaton c.Feldman c.Forsyth t.Frantzen G.Galgóczi J.Garcia G.Y.Genov c.Gordillo H-P.Gröbelbauer M.Guedel Y.Guo M.Hailey D.Hall R.Hampson J.Hasiba O.Hetherington A.Holland S-Y.Hsieh M.W.J.Hubbard H.Jeszenszky M.Jones t.Kennedy K.Koch-Mehrin S.Kögl S.Krucker K.D.Kuntz c.Lakin G.Laky O.Lylund A.Martindale J.Miguel Mas Hesse R.Nakamura K.Oksavik N.Østgaard H.Ottacher R.Ottensamer c.Pagani S.Parsons P.Patel J.Pearson G.Peikert F.S.Porter t.Pouliantis B.H.Qureshi W.Raab G.Randal A.M.Read N.M.M.Roque M.E.Rostad c.Runciman S.Sachdev A.Samsonov M.Soman D.Sibeck S.Smit J.Søndergaard R.Speight S.Stavland M.Steller tianRan Sun J.thornhill W.thomas K.Ullaland B.Walsh D.Walton c.Wang S.Yang School of Physics and Astronomy University of LeicesterLeicesterLE17RHUK Space Park Leicester University of LeicesterLeicesterLE17RHUK Mullard Space Science Laboratory University College LondonDorkingRH56NTUK centre for Electronic Imaging Open UniversityMilton KeynesMK76 AAUK Birkeland centre for Space Science Department of Physics and TechnologyUniv.of BergenN-5007 BergenNorway University of Vienna A-1010 ViennaAustria Space Research Institute Austrian Academy of SciencesA-8042 GrazAustria National Institute of Aerospace technology MadridSpain EStEc European Space Agency2201 AZ NoordwijkNetherlands State Key Laboratory of Space Weather National Space Science CentreBeijing 100190China University of Applied Sciences and Arts Northwestern Switzerland CH-5210 WindischSwitzerland Koegl Space GmbH CH-8157 DielsdorfSwitzerland Space Acoustics GmbH CH-8157 DielsdorfSwitzerland Zurich University of Applied Sciences 8400 WinterhurSwitzerland Genov Solutions N-5172 LoddefjordNorway StM Engineering N-5165 LaksevagNorway John Hopkins University Applied Physics Laboratory MD 20723USA NASA/Goddard Space Flight centre MD 20771USA center for Space Physics Boston UniversityBostonMA 02215USA Department of theoretical Physics and Astrophysics Masaryk University60177 BrnoCzech Republic Institute of Physics E¨otvo¨s Lor´and University1053 BudapestHungary Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100045China centro de Astrobiologia(cAB) CSIC-INTAMadridSpain

the Soft X-ray Imager(SXI)is part of the scientific payload of the Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)*** is a joint science mission between the European Space Agency(ESA)and the chinese Academy of Sciences(cAS)and is due for launch in *** is a compact X-ray telescope with a wide field-of-view(FOV)capable of encompassing large portions of Earth’s magnetosphere from the vantage point of the SMILE *** is sensitive to the soft X-rays produced by the Solar Wind charge eXchange(SWcX)process produced when heavy ions of solar wind origin interact with neutral particles in Earth’s *** provides a mechanism for boundary detection within the magnetosphere,such as the position of Earth’s magnetopause,because the solar wind heavy ions have a very low density in regions of closed magnetic field *** sensitivity of the SXI is such that it can potentially track movements of the magnetopause on timescales of a few minutes and the orbit of SMILE will enable such movements to be tracked for segments lasting many *** is led by the University of Leicester in the United Kingdom(UK)with collaborating organisations on hardware,software and science support within the UK,Europe,china and the United States.

关键词： Soft X-ray Imaging micropore optics large area ccD

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An improved pulse coupled neural networks model for semantic Iot

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Digital communications and Networks 2024年第3期10卷 557-567页

作者： Rong Ma Zhen Zhang Yide Ma Xiping Hu Edith c.H.Ngai Victor c.M.Leung School of Information Science and Engineering Lanzhou UniversityLanzhou 730000China School of Medical technology Beijing Institute of TechnologyBeijing100081China Department of Electrical and Electronic Engineer The University of Hong KongHong Kong 999077China college of computer Science and Software Engineering Shenzhen UniversityShenzhen 518060China Department of Electrical and computer Engineering the University of British ColumbiaVancouverBC V6T 1Z4Canada

In recent years,the Internet of things(Iot)has gradually developed applications such as collecting sensory data and building intelligent services,which has led to an explosion in mobile data ***,with the rapid development of artificial intelligence,semantic communication has attracted great attention as a new communication ***,for Iot devices,however,processing image information efficiently in real time is an essential task for the rapid transmission of semantic *** the increase of model parameters in deep learning methods,the model inference time in sensor devices continues to *** contrast,the Pulse coupled Neural Network(PcNN)has fewer parameters,making it more suitable for processing real-time scene tasks such as image segmentation,which lays the foundation for real-time,effective,and accurate image ***,the parameters of PcNN are determined by trial and error,which limits its *** overcome this limitation,an Improved Pulse coupled Neural Networks(IPcNN)model is proposed in this *** IPcNN constructs the connection between the static properties of the input image and the dynamic properties of the neurons,and all its parameters are set adaptively,which avoids the inconvenience of manual setting in traditional methods and improves the adaptability of parameters to different types of *** segmentation results demonstrate the validity and efficiency of the proposed self-adaptive parameter setting method of IPcNN on the gray images and natural images from the Matlab and Berkeley Segmentation *** IPcNN method achieves a better segmentation result without training,providing a new solution for the real-time transmission of image semantic information.

关键词： Internet of things(Iot) Semantic information Real-time application Improved pulse coupled neural network Image segmentation

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Analysis of the combined effect of rs699 and rs5051 on angiotensinogen expression and hypertension

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chronic Diseases and translational Medicine 2024年第2期10卷 102-117页

作者： Nicholas R.Powell tyler Shugg Jacob Leighty Matthew Martin Rolf P.Kreutz Michael t.Eadon Dongbing Lai tao Lu todd c.Skaar Division of clinical Pharmacology Department of MedicineSchool of MedicineIndiana UniversityIndianapolisIndianaUSA Department of Pharmacology and toxicology School of MedicineIndiana UniversityIndianapolisIndianaUSA Department of cardiology School of MedicineKrannert Institute of CardiologyIndiana UniversityIndianapolisIndianaUSA Division of Nephrology Department of MedicineSchool of MedicineIndiana UniversityIndianapolisIndianaUSA Department of Medical and Molecular Genetics School of MedicineIndiana UniversityIndianapolisIndianaUSA

Background Hypertension(HtN)involves genetic variability in the renin-angiotensin system and influences antihypertensive *** previously reported that angiotensinogen(AGt)messenger RNA(mRNA)is endogenously bound by miR-122-5p and rs699 A>G decreases reporter mRNA in the microRNA functional-assay *** AGt promoter variant rs5051 c>t is in linkage disequilibrium(LD)with rs699 A>G and increases AGt *** independent effect of these variants is understudied due to their LD therefore we aimed to test the hypothesis that increased AGt by rs5051 c>t counterbalances AGt decreased by rs699 A>G,and when these variants occur independently,it translates to HtN-related *** We used in silico,in vitro,in vivo,and retrospective models to test this *** In silico,rs699 A>G is predicted to increase miR-122-5p binding affinity by 3%.Mir-ecLIP results show rs699 is 40–45 nucleotides from the strongest microRNA-binding site in the AGt ***,rs699 A>G increases AGt mRNA in an AGt-plasmid-cDNA HepG2 expression ***-tissue Expression(GtEx)and UK Biobank analyses demonstrate liver AGt expression and HtN phenotypes are not different when rs699 A>G occurs independently from rs5051 c>***,GtEx and the in vitro experiments suggest rs699 A>G confers cell-type-specific effects on AGt mRNA abundance,and suggest paracrine renal renin-angiotensin-system perturbations could mediate the rs699 A>G associations with *** We found that rs5051 c>t and rs699 A>G significantly associate with systolic blood pressure in Black participants in the UK Biobank,demonstrating a fourfold larger effect than in White *** studies are warranted to determine if altered antihypertensive response in Black individuals might be due to rs5051 c>t or rs699 A>*** like this will help clinicians move beyond the use of race as a surrogate for genotype.

关键词： angiotensinogen genetic and genomic medicine hypertension rs699

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QcD sum rule study of J^(P)=1^(±)exotic states with two heavy quarks in the molecular picture

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chinese Physics c 2024年第6期48卷 31-37页

作者： t.M.Aliev S.Bilmis M.Savcı Department of Physics Middle East Technical UniversityAnkara06800Turkey tUBItAK ULAKBIM Ankara06510Turkey

In this study,the spectroscopic parameters of exotic molecular states composed of mesons containing two heavy quarks(scalar-axial and pseudoscalar-axial meson combinations)are investigated within the QcD sum *** findings reveal that molecular states containing charm quarks do not form bound states,whereas states with b-quarks can form exotic molecular *** observation has significant implications for understanding the structure of these exotic states.

关键词： QcD sum rules exotic mesons molecular states

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Analysis of strong decays of SU(3)partners ofΩ(2012)baryon

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chinese Physics c 2024年第8期48卷 34-41页

作者： t.M.Aliev S.Bilmis M.Savci Department of Physics Middle East Technical UniversityAnkara 06800Turkey tUBItAK ULAKBIM Ankara 06510Turkey

We estimate the coupling constants and decay widths of the SU(3)partners of theΩ(2012)hyperon,as discovered by the BELLE collaboration,using the distribution amplitudes of the octet baryons within the light cone sum rules *** study includes a comparison of the obtained results for the relevant decay widths with those derived within the framework of the flavor SU(3)*** observe a good agreement between the predictions of both ***,our result on the decay width ofΩ→ΞK is compatible with the existing experimental result within the uncertainties of the model *** results can provide helpful insights for determining the nature of the SU(3)partners of theΩ(2012)baryon.

关键词： coupling constants light cone sum rule hyperon

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Experimental and numerical analysis of multi-chamber oscillating water column devices

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Journal of Hydrodynamics 2024年第3期36卷 492-503页

作者： Jorge Gadelho Kourosh Rezanejad c.Guedes Soares centre for Marine technology and Ocean Engineering(cENtEc) Instituto Superior TécnicoUniversidade de LisboaAvenida Rovisco PaisLisboaPortugal

A review of multi-chamber oscillating water column(OWc)device designs is *** significant variations of these devices are discussed,onshore OWc(OOWc)and a floating OWc(FOWc).the efficiency results of several theoretical studies based on low-and high-fidelity numerical models are presented and compared with the model scale ***,low-fidelity numerical models are very fast to run,but their accuracy is limited compared with high-fidelity numerical *** model experiments usually give results much more accurate than numerical models,but they need adequate facilities and are very *** the case of the OOWc,all models show a similar trend of total efficiency,but while the analytical model shows a maximum value of around 90%efficiency,the cFD model shows 60%,and the experiments only go up to 40%.the main reason is connected with the mathematical simplifications and assumptions that do not represent all the hydrodynamic and aerodynamic processes between the water,air,and *** the case of the FOWc,interestingly,the experimental results show a maximum efficiency of almost 100%,while the analytical model only predicts a maximum of 80%.the efficiency seems highly dependent on the heave motion resonance of the entire device,where the analytical model fails to predict this natural frequency.

关键词： Wave energy converters oscillating water column(OWc) multi-chambers experimental modelling numerical modelling

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tensor force impact on shell evolution in neutron-rich Si and Ni isotopes

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chinese Physics c 2024年第4期48卷 95-106页

作者： S.V.Sidorov A.S.Kornilova t.Yu.tretyakova Faculty of Physics Lomonosov Moscow State UniversityMoscow 119991Russia Skobeltsyn Institute of Nuclear Physics Lomonosov Moscow State UniversityMoscow 119991Russia

the influence of the tensor interaction of nucleons on the characteristics of neutron-rich silicon and nickel isotopes was studied in this *** forces are considered within the framework of the Hartree-Fock approach with the Skyrme *** addition of a tensor component of interaction is shown to improve the description of the splittings between different single-particle states and decrease nucleon-nucleon pairing correlations in silicon and nickel *** attention was directed toward the role of isovector tensor forces relevant to the interaction of like nucleons.

关键词： nuclear shell model tensor interaction silicon isotopes nickel isotopes

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Effect of biochar on the metabolome of soybean seedlings

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Oil crop Science 2024年第1期9卷 60-68页

作者： Nathalia E.Silva Mariana G.Aguilar Osania E.Ferreira Gleicia M.Paulino Jaqueline c.L.carvalho Lúcia P.S.Pimenta Alan R.t.Machado Programa de Pos-graduaçao em ciencias Ambientais Universidade do Estado de Minas GeraisFrutalMinas Gerais38202-436Brazil Departamento de Química Universidade Federal de Minas GeraisMinas GeraisBelo Horizonte31270-901Brazil Departamento de Engenharia Aplicada e tecnologias Ambientais Universidade do Estado de Minas GeraisJoao MonlevadeMinas Gerais35930-314Brazil Departamento de ciencias Exatas Universidade do Estado de Minas GeraisJoao MonlevadeMinas Gerais35930-314Brazil

the use of biochar can have several effects on plant germination,depending on raw material,preparation method and application ***,the molecular mechanisms that lead to those results have yet to be *** aim of this research was to improve the understanding of these mechanisms by characterizing the metabolic effects of sugarcane bagasse biochar on soybean *** types of biochars were prepared by pyrolysis at 300℃(ScB300),400℃(ScB400)and 600℃(ScB600).then,each one was mixed into sand at 1%,3%,5%(w/w)dose,*** experiment was performed in 8 days of incubation,when the number of germinated seeds and the average radicle length were *** evaluate the metabolome,the dry biomass(DB)was subjected to extraction with a mixture of methanol-d4 and D2O(1:1 v/v).the extracts were submitted to metabolomics analysis by Proton Nuclear Magnetic *** Relative Germination,Relative Average Radicle Growth and Germination Index increased in all treatments compared to *** the other hand,the DB increased in all treatments,except for ScB300,at doses of 1%and 3%w/*** metabolites(alanine,asparagine,acetic acid,citric acid,glycerol,fatty acids and sucrose)were identified and quantified in DB extracts as the most influential finding for the separation of *** together,these results strongly suggested that biochars accelerated the catabolism of triacylglycerols to sucrose and induced a slight osmotic stress.

关键词： Germination Metabolomics 1H NMR Pyrolysis Sugarcane bagasse

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