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世界核心医学期刊文摘（神经病学分册） 2005年第8期1卷 44-45页

作者： del ser t. Hachinski V. Merskey H. Munoz d.G. 张玉龙 sección de Neurologa Hospital Severo Ochoa Avda.Orellana s/n Leganés 28911 Madrid Spain

Objective: to compare the clinical and pathological features of Alzheimer’s d isease (Ad) patients with and without associated cerebral infarcts (CI). Methods : the consecutive records of 57 prospectively studied demented patients fulfilli ng the CERAd criteria for the pathological diagnosis of Ad were *** w ith cortical Lewy bodies were excluded. CI were found in 22 cases (39%) (Ad+CI group): large infarcts (5), lacunes(13) and/or hip pocampal sclerosis (4), and were absent in 35cases (Ad group). Microscopic inf arcts, cribiform change,amyloid angiopathy, and white matter rarefaction were no t considered in this classification, but were quantified. Corticalatrophy, neuro fibrillary tangle and senile plaque (diffuse and neuritic) load were also measur ed. Pathological evaluation was independent of clinical information. Clinical an d pathological data were compared between both groups. Results: Ad+CI cases wer e significantly older, more commonly female, less educated, and more often had b lue collar occupations, sleep disturbances, frontal release signs, and EEG spike s than Ad cases. Other differences found (acute/subacute onset, behavioral distu rbances, and leukoaraiosis on Ct scan) disappeared after controlling for age. th e frequency of known vascular risk factors and focal motor and sensory signs did not differ between the groups, which showed remarkable clinical similarity over all. the only significant differences on pathological exam were hippocampal micr oinfarcts and white matter lesions,although there was a trend for lower neurodeg enerative lesion load in the Ad+CI group. the ischemic lesions were located in temporal lobe in 50%of Ad+CI patients; these cases had a significantly lower n eocortical neurodegenerative lesion load than those with CI in other sites. Conc lusions: the presence of CI in Ad increases significantly with age, but has scar ce influence on the clinical features, and cannot be predicted from common vascu lar risk factors.

关键词：阿尔茨海默病神经纤维缠结淀粉样血管病血管危险因素皮质萎缩大面积梗死白质病变神经变性海马硬化脑白质疏松症

异位化骨中的胶原和生长因子——非放射性原位杂交的经验

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德国医学 1996年第1期13卷 54-57页

作者： A.bosse M.Wulf t.Wiethege b.Voss K.-M.Mller 阮幼冰 Institut für Pathologie BG-Kliniken"Bergmannsheil"UniversittsklinikGilsingerstr.14D-44789 BochumGermany 同济医科大学

胶原及生长因子均属骨发生的组成部分。在生长因子中,特别是作为调节蛋白的 tGF-β在骨母细胞分化过程中具有重要意义。在异位化骨中,目前尚无各种胶原及 tGF-β的 mRNA 的分布模式。本文拟在异位化骨早期形成期。

关键词：异位化骨胶原生长因子原位杂交

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形而上学的国家论

丛书名：汉译世界学术名著丛书

1997年

作者：（英）L.t.霍布豪斯（L.t. Hobhouse）汪淑钧译

本书是作者专为批判黑格尔及其在英国的追随者鲍桑葵的“形而上学的国家论”而写的。作者认为形而上学的国家论否认理想与现实的区别，将现实理想化，断言国家是绝对精神的体现，是上帝的化身，因此国家是对个人具有最高权利的最终目的... 详细信息

ISBN: (纸本)7100032288

本书是作者专为批判黑格尔及其在英国的追随者鲍桑葵的“形而上学的国家论”而写的。作者认为形而上学的国家论否认理想与现实的区别，将现实理想化，断言国家是绝对精神的体现，是上帝的化身，因此国家是对个人具有最高权利的最终目的，个人的最高义务就是做国家的成员，服从国家。

关键词：国家理论

来源：汇雅图书（南通市图书馆... 评论

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IgG4是妊娠性类天疱疮的主要IgG亚型

世界核心医学期刊文摘（皮肤病学分册） 2006年第6期2卷 61-62页

作者： Patton t. Plunkett R.W. beutnerE.H. d.M. Jukic 冯义国 dermatopathology Unit Shadyside Hospital University of Pittsburgh Medical Center Centre Avenue Pittsburgh PA United States Dr.

background: Pemphigoides gestationis (PG) is a blistering disorder of pregnancy caused by antibodies against basement membrane proteins. they are directed against the 180 kd bullous pemphigoid antigen (bPAg2), towards the epitopes within the NC 16A domain. there are many similarities between pemphigoid gestationis and bullous pemphigoid (bP), but the literature so far indicated different immunofluorescence results in regards with C3 and IgG, and IgG subclasses (IgG4 vs. IgG1). Methods: We evaluated staining patterns and IgG subclasses, as well as C5b-9 membrane attack complex (MAC) in 10 pregnant patients with PG, using sandwich double antibody immunofluorescence (sdAI) and direct immunofluorescence (dIF). Results: All ten specimens stained with C3 by dIF, but only five had trace amount of IgG reactants by this method. by sdAI, 100%were positive for the IgG4 and C5b-9 MAC, 70%for IgG2, 50%for IgG1, and 40%for IgG3. Conclusion: IgG4 was the predominant IgG subtype identified. this finding has not been reported for PG, but it mimics results reported for bP. One explanation is prolonged disease course, as well as blocking of antigenic domains by IgG4. Understanding this completely will help develop therapies and prevention strategies for immunobullous and other autoimmune diseases, and perhaps aid in an exact classification.

关键词：大疱性类天疱疮 IgG亚型 IgG4 妊娠性直接免疫荧光技术自身免疫性疾病基底膜蛋白 C5b-9 双抗体检测分析

dexamethasone Reduces IL-17 and tim-3 Expression in bALF of Asthmatic Mice

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Journal of Huazhong University of science and technology(Medical sciences) 2013年第4期33卷 479-484页

作者：陆小霞 Karen s.McCoy 胡维琨徐佳莉王海勤陈鹏陈和斌 department of Pulmonary Medicine Wuhan Women and Children Health Care Center department of Pediatrics Division of Pulmonary MedicineNationwide Children's Hospital and The Ohio State University School of Medicine and Public Health department of Ophthalmology Tongji HospitalTongji Medical CollegeHuazhong University of Science and Technology

summary： this study investigated the expression of interleukin-17 （IL-17） and t cell immunoglobulin mucin and domain-containing molecule-3 （tim-3） in bronchoalveolar lavage fluid （bALF） of asthmatic mice and the effect of dexamethasone （dEX） on these factors. thirty-six mice were randomly divided into three groups： normal group, asthmatic group and dEX group. the mouse model of asthma was es- tablished by sensitization with ovalbumin in both the asthmatic and dEX groups. the levels of IL-6, IL-10, IL-17 and tGF-β were measured in bALF by enzyme-linked immunesorbent assay （ELIsA）. the mRNA expression level of tim-3 was detected by reverse transcription polymerase chain reaction （Rt-PCR）. the ratio of tim-3＋Cd4＋ cells to total Cd4＋ cells in bALF was determined by flow cy- tometry. differential inflammatory cells in bALF were detected. the correlations among IL-17, IL-6, IL-10, tim-3 and inflammatory cells were analyzed. the results showed that the levels of IL-17, IL-6 and tim-3 were substantially increased and the IL-10 level decreased in bALF in the asthmatic mice, which was significantly reversed by dEX treatment. IL-17 expression was positively correlated with IL-6 and tim-3 expression and the number of inflammatory cells but negatively with IL-10 expression. these results indicate that the increased expression of IL-17 and tim-3 in bALF may be implicated in the occurrence and development of asthmatic inflammation; the mechanism by which dEX suppresses asthmatic airway inflammation involves down-regulation of IL-17 and tim-3 levels.

关键词： asthma thl7 cells tim-3 cytokines corticosteroids

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节能型嵌入式系统的系统级设计技术

国外科技新书评介 2006年第7期 17-18页

作者： M．t．施密兹 b．M．奥-哈希姆 P．埃莱斯丁丹 University of southampton UK Linkoeping University Sweden 中国科学院计算技术研究所硕士生

现在对于低功耗的嵌入式计算系统的需求持续上升。信息技术的发展使得集成电路单位面积上集成的晶体管越来越多，这就必然导致单位面积上的功耗越来越大，局部过热会让晶体管处于不稳定状态，因此，低功耗技术的研究意义十分重大。本书... 详细信息

现在对于低功耗的嵌入式计算系统的需求持续上升。信息技术的发展使得集成电路单位面积上集成的晶体管越来越多，这就必然导致单位面积上的功耗越来越大，局部过热会让晶体管处于不稳定状态，因此，低功耗技术的研究意义十分重大。本书主要讨论节能型嵌入式系统的有效自动设计技术的开发和验证，重点介绍了嵌入式系统的系统级同步综合技术，包括动态电压调度处理器技术。这种技术在性能和功耗之间权衡，使得系统低功耗高性能。

关键词：嵌入式系统设计技术系统级节能型低功耗技术单位面积集成电路不稳定状态计算系统信息技术

光子放射外科系统对体外培养脉络丛细胞的放射生物学效应

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华中科技大学学报（医学版） 2004年第6期33卷 704-706页

作者：牛洪泉 Klaus Eckhardt Christoph b. Ostertag 华中科技大学同济医学院附属同济医院神经外科 Neurochirurgische Universitaetsklinik Abteilung Stereotaktische NeurochirurgieNeurozentrumFreiburgGermanyD79106

目的　研究脉络丛 (CP)细胞对光子放射外科系统 (PRs)照射后的反应 ,为脑积水的治疗提供新的思路。方法　体外培养绵羊脉络丛 (sCP)细胞 ,观察其对不同剂量PRs照射后的反应 ,采用锥虫蓝 (tb)染色法和 3 (4,5 二甲基噻唑基 ) 2 ,5 二... 详细信息

目的　研究脉络丛 (CP)细胞对光子放射外科系统 (PRs)照射后的反应 ,为脑积水的治疗提供新的思路。方法　体外培养绵羊脉络丛 (sCP)细胞 ,观察其对不同剂量PRs照射后的反应 ,采用锥虫蓝 (tb)染色法和 3 (4,5 二甲基噻唑基 ) 2 ,5 二苯基四氮唑溴化物 (Mtt)法检测细胞死亡。结果　随着照射剂量的增高 (9～ 36Gy) ,sCP细胞存活率降低 ,有剂量依赖效应。低剂量组 (9和 18Gy)照射开始引起细胞存活率降低 ,但受照细胞从第 6天起活性逐渐恢复 ,至第 12天时和对照组比较差异无显著性意义。而高剂量组 (2 7和 36Gy)在 12d内引起细胞存活率持续降低 ,不能恢复。结论　光子放射外科系统 (PRs)照射可在体外引起具有脑脊液分泌功能的CP细胞的死亡。

关键词：放射外科细胞存活率脉络丛照射体外培养放射生物学 CP 溴化物 PRs 苯基

偏头痛和紧张型头痛的预后:一项基于人群的随访研究

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世界核心医学期刊文摘(神经病学分册) 2006年第1期 31-32页

作者： Lyngberg A.C. Rasmussen b.K. J.rgensen t. Jensen R. 谢琰臣 Research Centre for Prevention and Health Glostrup University Hospital Building 84/85 Nordre Ringvej 57 DK-2600 Glostrup Denmark Dr.

Objective: to determine the prognosis of migraine and tensiontype headache and to identify prognostic factors. Methods: Of 740 persons (aged 25 to 64 years) examined in a 1989 danish cross-sectional headache study, 673 were eligible for follow-up in 2001. All interviews at baseline and at follow-up were conducted by medical doctors and based on the 1988 IHs criteria. Results: A total of 549 persons (81.6%) participated in the follow-up study. Of 64 migraineurs at baseline, 42%had experienced remission, 38%had low migraine frequency, and 20%had more than 14 migraine days per year (poor outcome) at follow-up. Poor outcome was associated with high migraine frequency at baseline and age at onset younger than 20 years. Among 146 subjects with frequent episodic tension-type headache and 15 with chronic tension-type headache at baseline, 45%experienced infrequent or no tension-type headache (remission), 39%had frequent episodic tension-type headache, and 16%experienced chronic tension-type headache (poor outcome) at follow-up. Poor outcome was associated with baseline chronic tension-type headache, coexisting migraine, not being married,and sleeping ***:the prognosis of migraine, frequent episodic tension-type headache, and chronic tension-type headache was favorable.

关键词：偏头痛脑病紧张型随访研究预后

determination of the number of J/ψ events with inclusive J/ψ decays

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Chinese Physics C 2017年第6期41卷 1-10页

作者：麦迪娜 M.N.Achasov 艾小聪 O.Albayrak M.Albrecht d.J.Ambrose A.Amoroso 安芬芬安琪白景芝 R.baldini Ferroli 班勇 d.W.bennett J.V.bennett M.bertani d.bettoni 边渐鸣 F.bianchi E.boger I.boyko R.A.briere 蔡浩蔡啸 O.Cakir A.Calcaterra 曹国富 s.A.Cetin 常劲帆 G.Chelkov 陈刚陈和生陈海云陈江川陈玛丽陈申见谌炫陈旭荣陈元柏程和平褚新坤 G.Cibinetto 代洪亮代建平 A.dbeyssi d.dedovich 邓子艳 A.denig I.denysenko M.destefanis F.de Mori 丁勇董超董静董燎原董明义豆正磊杜书先段鹏飞范荆州方建房双世方馨方易 R.Farinelli L.Fava O.Fedorov F.Feldbauer G.Felici 封常青 E.Fioravanti M.Fritsch 傅成栋高清高鑫磊高旭阳高原宁高榛 I.Garzia K.Goetzen 龚丽龚文煊 W.Gradl M.Greco 顾旻皓顾运厅管颖慧郭爱强郭立波郭玥郭玉萍 Z.Haddadi A.Hafner 韩爽郝喜庆 F.A.Harris 何康林 t.Held 衡月昆侯治龙胡琛胡海明胡继峰胡涛胡誉黄光顺黄金书黄性涛黄勇 t.Hussain 纪全姬清平季晓斌季筱璐姜鲁文江晓山蒋兴雨焦健斌焦铮金大鹏金山 t.Johansson A.Julin N.Kalantar-Nayestanaki 康晓琳康晓珅 M.Kavatsyuk 柯百谦 P.Kiese R.Kliemt b.Kloss 0.b.Kolcu b.Kopf M.Kornicer A.Kupsc W.Kuhn J.s.Lange M.Lara P.Larin C.Leng 李翠李澄李德民李飞李峰云李刚李海波李家才李瑾李科李康李蕾李培荣李启云李腾李卫东李卫国李晓玲李小男李学潜李志兵梁昊梁勇飞梁羽铁廖广睿林德旭刘北江刘春秀刘栋刘福虎刘芳刘峰刘宏邦刘欢欢刘慧慧刘怀民刘杰刘建北刘觉平刘晶译刘凯刘魁勇刘兰雕刘佩莲刘倩刘树彬刘翔刘玉斌刘振安刘智青 H.Loehner 娄辛丑吕海江吕军光卢宇卢云鹏罗成林罗民兴 t.Luo 罗小兰吕晓睿马凤才马海龙马连良马秋梅马天马旭宁马骁妍马玉明 F.E.Maas M.Maggiora 冒亚军毛泽普 s.Marcello J.G.Messchendorp 闵建闵天觉 R.E.Mitchell 莫晓虎莫玉俊 C.Morales Morales N.Yu.Muchnoi H.Muramatsu Y.Nefedov F.Nerling I.b.Nikolaev 宁哲 s.Nisar 牛顺利牛讯伊马鹏欧阳群 s.Pacetti 潘越 P.Patteri M.Pelizaeus 彭海平 K.Peters J.Pettersson 平加伦平荣刚 R.Poling V.Prasad 漆红荣祁鸣钱森乔从丰秦丽清覃拈秦小帅秦中华邱进发 K.H.Rashid C.F.Redmer M.Ripka 荣刚 Ch.Rosner 阮向东 V.santoro A.sarantsev M.savrie K.schoenning s.schumann 单葳邵明沈成平沈培迅沈肖雁盛华义宋维民宋欣颖 s.sosio s.spataro 孙功星孙俊峰孙胜森孙勇杰孙永昭孙志嘉孙振田唐昌建唐晓 I.tapan E.H.thorndike M.tiemens M.Ullrich I.Uman G.s.Varner 王斌王滨龙王东王大勇王科王亮亮王灵淑王萌王平王佩良王炜王维平王雄飞王雅迪王贻芳王亚乾王铮王志刚王志宏王至勇 t.Weber 魏代会 P.Weidenkaff 文硕频 U.Wiedner M.Wolke 伍灵慧吴智夏磊夏力钢夏宇肖栋肖浩肖振军谢宇广修青磊许国发徐雷徐庆君徐庆年徐新平严亮鄢文标闫文成颜永红杨海军杨洪勋杨柳杨永栩叶梅叶铭汉殷俊昊俞伯祥喻纯旭俞洁晟苑长征袁文龙袁野 A.Yuncu A.A.Zafar A.Zallo 曾云曾哲张丙新张炳云张驰张长春张达华张宏浩章红宇张佳佳张杰磊张敬庆张家文张建勇张景芝张坤张磊张学尧张瑶张银鸿张宇宁张亚腾 Institute of High Energy Physics G.I. budker Institute of Nuclear Physics sb RAs (bINP) the Novosibirsk state University Carnegie Mellon University bochum Ruhr-University University of Rochester University of turin INFN University of science and technology of China state Key Laboratory of Particle detection and Electronics INFN Laboratori Nazionali di Frascati Peking University Indiana University INFN sezione di Ferrara University of Minnesota Joint Institute for Nuclear Research the Moscow Institute of Physics and technology Wuhan University Ankara University Istanbul bilgi University the Functional Electronics Laboratory Tomsk State University beihang University Nanjing University Lanzhou University Huangshan College shanghai Jiao tong University Helmholtz Institute Mainz Johannes Gutenberg University of Mainz Liaoning University Nankai University Zhengzhou University tsinghua University University of Ferrara University of Eastern Piedmont GsI Helmholtzcentre for Heavy Ion Research GmbH Guangxi University Nanjing Normal University KVI-CARt University of Groningen Henan Normal University University of Hawaii shandong University University of the Punjab Uppsala University Istanbul Arel University Justus-Liebig-Universitaet Giessen Ⅱ. Physikalisches Institut seoul National University Hangzhou Normal University beijing Institute of Petrochemical technology University of Chinese Academy of sciences sun Yat-sen University sichuan University Guangxi Normal University shanxi University Central China Normal University Henan University of science and technology University of texas at dallas Zhejiang University COMsAts Institute of Information technology INFN and University of Perugia Goethe University Frankfurt the NRC "Kurchatov Institute PNPI Uludag University Near East University Hunan University University of south China soochow University Institute of Nuclear and Particle Physics Shanghai Key Laboratory for Particle Physics and Cosmology China Center of Advanced science and technology bogazici University Univers

A measurement of the number of J/ψ events collected with the bEsⅢ detector in 2009 and 2012 is performed using inclusive decays of the J/ψ. the number of J/ψ events taken in 2009 is recalculated to be（223.7±1.4）×10^6, which is in good agreement with the previous measurement, but with significantly improved precision due to improvements in the bEsⅢ software. the number of J/ψ events taken in 2012 is determined to be（1086.9±6.0）×10^6. In total, the number of J/ψ events collected with the bEsⅢ detector is measured to be（1310.6±7.0）×10^6, where the uncertainty is dominated by systematic effects and the statistical uncertainty is negligible.

关键词： number of J/ψ events bEsⅢ detector inclusive J/ψ events