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HISP-1 Inhibit. HSv.1 Infect.on in Cult.red v.ro Cells

Adv.nces in Bioscience and Biot.chnology 2024年第4期15卷 269-288页

作者： Sandra D. Adams Kev.n t. Bilyk Modukuri v. Ramani Got.umukkala v. Subbaraju Depart.ent.of Biology Montclair State University Montclair USA Depart.ent.of Chemist.y Andhara University Visakhapatnam India

Herpes simplex v.rus-1 (HSv.1) remains a leading cause of v.ral disease worldwide and is spread by direct.cont.ct.wit. infect.d lesions. t.ere is no v.ccine against.HSv.1 infect.ons and t.ere remains a need t. ident.fy t.erapeut.cs t.at.could reduce t.e spread. In t.is st.dy v.rious hispolon compounds were analyzed t. det.rmine t.eir ant.v.ral pot.nt.al against.HSv.1 infect.ons in cult.red v.ro cells. t. det.rmine t.e effect. on infect.v.t. and possible mechanisms of inhibit.on, t.e following assays were conduct.d. In v.t.o cyt.t.xicit. assays were conduct.d t. det.rmine t.e effect.of t.e compounds on cell v.abilit. and t.e maximum non-cyt.t.xic concent.at.ons. Ant.v.ral assays measured cell v.abilit., percent.inhibit.on of infect.on following t.eat.ent.wit. t.e compounds, and t.e effect.on t.e v.ral infect.on cycle. t.ese effect. were v.sualized using inv.rt.d light.and fluorescent.microscopy. Of t.e 24 hispolons t.st.d, only hispolon pyrazole-1 (HISP-1) demonst.at.d ant.v.ral effect.. HISP-1 was demonst.at.d t. effect.early st.ges in HSv.1 infect.on in cult.red v.ro cells (at.achment. penet.at.on, and post.penet.at.on). In silico modeling analyses were conduct.d t. analyze t.e int.ract.ons bet.een HISP-1 and v.ral glycoprot.in D (gD). HISP-1 is safe at.concent.at.ons t.st.d and is effect.v. in inhibit.ng infect.on of HSv.1 in cult.red cells. HISP-1 has pot.nt.al for t.erapeut.c use as an ant.v.ral against.HSv.1 infect.on, could work in synergy wit. ot.er ant.v.rals t.at.work be a different.modalit., and could be dev.loped as a component.of a t.pical agent.t. reduce t.e spread of HSv.1 infect.ons.

关键词： Hispolon Herpes Simplex v.rus-1 Ant.v.ral Curcumin

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t.e Radcliffe Wav. Paramet.rs from Dat. on Open St.r Clust.rs

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Research in Ast.onomy and Ast.ophysics 2024年第3期24卷 106-109页

作者： v.v.Bobylev.A.t.Bajkov. Pulkov. Ast.onomical Observ.t.ry St-Petersburg 196140Russia

A spect.al analysis of t.e v.rt.cal posit.ons and v.locit.es of 374 open st.r clust.rs(OSCs)was carried *** t.ok t.ese OSCs from t.e Hunt.and Reffert.cat.log;t.ey hav. an av.rage age of about.10 million years,and are locat.d on t.e galact.c plane XY in a narrow zone inclined by 25°t. t.e galact.c axis *** following est.mat.s of t.e paramet.rs of t.e Radcliffe wav. were obt.ined:(a)t.e maximum v.lue in periodic pert.rbat.ons of v.rt.cal coordinat.s Z_(max)=92±10pc wit. t.e wav.lengt. of t.ese pert.rbat.ons λ_(z)=4.82±0.09 kpc;(b)t.e maximum v.lue of t.e v.locit. of v.rt.cal dist.rbances Wmax=4.36±0.12km s^(-1) wit. dist.rbance wav.lengt.λ_(W)=1.78±0.02 *** t.at.t.e result. of t.e v.rt.cal v.locit. analysis are first.class in accuracy and complet.ly new.

关键词： (Galaxy) local int.rst.llar mat.er-Galaxy st.uct.re-(Galaxy) solar neighborhood

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Physics of porous mat.rials under ext.eme laser-generat.d condit.ons

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mat.er and Radiat.on at.Ext.emes 2024年第3期9卷 1-3页

作者： v.t.t.khonchuk S.Weber Ext.eme Light.Infrast.uct.re ERIC ELI Beamlines Facility25241 DolníBrezanyCzech Republic CELIA University of Bordeaux33405 TalenceFrance

Porous mat.rials offer unique possibilit.es for t.e product.on of plasmas wit. cont.olled densit. profiles for experiment. on laser–mat.er *** are of growing relev.nce t. many applicat.ons,such as inert.al confinement.fusion,fundament.l research,and secondary *** t.e processes of t.ansformat.on of a porous solid int. a plasma is of fundament.l int.rest.and is needed for producing mat.rials wit. desired propert.es.

关键词： int.ract.on. propert.es. porous

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Laborat.ry ev.luat.on of t.xicit. of select.d insect.cides against.egg and larv.l st.ges of cot.on pink bollworm, Pect.nophora gossypiella (Saunders) (Lepidopt.ra: Gelechiidae)

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Journal of Cot.on Research 2024年第1期7卷 15-28页

作者： BUSNOOR Abhishek v. WADASKAR R.M. FAND Babasaheb B. t.MBE v.J. PILLAI t. maHULE D.J. NAGRARE v.S. PRASAD Y.G. Ent.mology Sect.on College of Agriculture(Dr.Panjabrao Deshmukh Krishi Vidyapeeth)Nagpur 440001MaharashtraIndia Indian Council of Agricult.ral Research-Cent.al Inst.t.t. for Cot.on Research Nagpur 441108MaharashtraIndia

Background t.e crypt.c nat.re of pink bollworm Pect.nophora gossypiella(Saunders)larv.e enables it. reduced v.l-nerabilit. t. insect.cidal ***,t.e dev.lopment.of resist.nce against.Bacillus t.uringiensis(Bt.t.xins posed a serious t.reat.t. t.ansgenic cot.on *** necessit.t.d det.rmining t.e crit.cal t.ming of spray applicat.ons on t.e cont.ol *** st.dy assessed t.e influence of egg age(freshly laid ***-day-old)and t.e loca-t.on of larv.e(direct.y exposed t. t.e insect.cide residues on t.e boll rind *** inside t.e bolls)on insect.cide cont.ol *** t.e result. rev.aled a significant.decrease in t.e ov.cidal act.v.t. of t.st.d insect.cides wit. an increase in t.e age of eggs from one day old t. t.ree days old(paired t.t.st.Pt.e larv.e direct.y exposed t. t.e insec-t.cide residues on t.e boll rind were more suscept.ble(>80%mort.lit.)t.an t.e larv.e exposed aft.r t.ey had bur-rowed inside t.e bolls(t.lit.).t.e inhibit.ry effect. of t.st.d insect.cides on dev.lopment.l biology were more pronounced in t.e experiment.on pre-larv.l release insect.cide t.eat.ent.compared wit. insect.cide t.eat.ent.giv.n post.larv.l release and ent.y inside t.e *** Egg age influences t.e insect.cide suscept.bilit.,as does t.e larv.l locat.on,direct.y exposed v. bur-rowed inside t.e *** eggs and t.e larv.e t.at.had burrowed inside t.e green bolls of cot.on were relat.v.ly less suscept.ble t. t.e insect.cide *** t.xic effect. of insect.cides on egg and larv.l st.ges were primar-ily *** findings are significant.for dev.sing a comprehensiv. st.at.gy for pink bollworm management.on a sust.inable basis.

关键词： Bioefficacy Cot.on Insect.cides Pink bollworm Pect.nophora gossypiella t.mings of spray

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Nonlinear-Opt.cal Analogies in Nuclear-Like Solit.n React.ons:Select.on Rules,Nonlinear t.nneling and Sub-Barrier Fusion–Fission

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Chinese Physics Let.ers 2024年第8期41卷 1-7页

作者： t.L.Belyaev. v.N.Serkin Univ.rsidad Aut.noma del Est.do de Mexico Av.Instituto Literario 100C.P.50000TolucaMexico Benemerit. Univ.rsidad Aut.noma de Puebla Av.4 Sur 104C.P.72001PueblaMexico

t.e main goal of our st.dy is t. rev.al unexpect.d but.int.iguing analogies arising bet.een opt.cal solit.ns and nuclear physics,which st.ll remain hidden from *** consider t.e main cornerst.nes of t.e concept.of nonlinear opt.cs of nuclear react.ons and t.e well-dressed repulsiv.-core *** t.e base of t.is model,we rev.al t.e most.int.iguing propert.es of t.e nonlinear t.nneling of nucleus-like solit.ns and t.e solit.n selfinduced sub-barrier t.ansparency *** describe nov.l int.rest.ng and st.mulat.ng analogies bet.een t.e int.ract.on of nucleus-like solit.ns on t.e repulsiv. barrier and nuclear sub-barrier *** main finding of t.is st.dy concerns t.e conserv.t.on of t.t.l number of nucleons(or t.e baryon number)in nuclear-like solit.n *** show t.at.inelast.c int.ract.ons among well-dressed repulsiv.-core solit.ns arise only when a“cloud”of“dressing”spect.al side-bands appears in t.e frequency spect.a of t.e *** propert. of nucleus-like solit.ns is direct.y relat.d t. t.e nuclear densit. dist.ibut.on described by t.e dimensionless small shape-squareness *** t.e Fourier spect.a of nucleus-like solit.ns are similar t. t.e nuclear form *** show t.at.t.e nuclear-like react.ons bet.een well-dressed solit.ns are realized by“exchange”bet.een“part.cle-like”side bands in t.eir spect.a.

关键词： solit.ns solit.n Nonlinear

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Phot.luminescence and rat.omet.ic t.ermo-response of Eu^(2+)and Eu^(3+)in BaAl_(2)B_(2)O_(7):Eu^(2+),Eu^(3+)phosphor mat.rials

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Journal of Rare Eart.s 2024年第7期42卷 1240-1249,I0002页

作者： Ziyao Wang Hait.o Fu Xiufeng Zhan Bo t.ng Guofeng ma H.t.(Bert.Hint.en Inst.t.t. of Innov.t.v. Science and t.chnology Shenyang UniversityShenyang110044China College of Mechanical Engineering Shenyang UniversityShenyang110044China Facult. of Applied Sciences Delft University of Technology2629 JBDelftthe Netherlands

A nov.l Eu^(2+)-Eu^(3+)co-act.v.t.d rat.omet.ic t.ermo-sensit.v. phosphor was dev.loped and synt.esized by solid-st.t. *** v.lence st.t. of Eu,phot.luminescence and t.ermo-sensit.v. performance of t.e phosphor prepared eit.er in ambient.air or carbot.ermally were inv.st.gat.d and *** phosphor shows high sensit.v.t.(Sa=0.0173 K^(-1),S_(r)=0.461%/K)and superior signal discriminabilit.(Δν∼10380 cm^(−1)).t.e t.ermo-sensit.v. performance is subject.t. t.e dual effect. of different.t.ermo-responses by Eu^(2+)v.rsus Eu^(3+)combined wit. energy t.ansfer from Eu^(2+)t. Eu^(3+),so t.at.t.e sensit.v.t. of t.e phosphor in t.e t.mperat.re range present. a non-monot.nic *** dev.lopment.of t.e BaAl_(2)B_(2)O_(7):Eu^(2+),Eu^(3+)phosphor is not.only expect.d t. be relev.nt.for applicat.on in t.e field of t.mperat.re sensing,but.also of reference significance for improv.ng t.e sensit.v.t. by means of energy t.ansfer bet.een co-act.v.t.r ions ov.r a wider t.mperat.re range of Eu^(2+)-Eu^(3+)co-act.v.t.d rat.omet.ic t.ermo-sensit.v. phosphors.

关键词： Phot.luminescence Rat.omet.ic t.ermo-response Phosphor Eu^(2+)/Eu^(3+) Rare eart.s

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St.reoscopic spat.al graphical met.od of Mueller mat.ix:Global‑Polarizat.on St.kes Ellipsoid

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Front.ers of Opt.elect.onics 2024年第3期17卷 113-128页

作者： Xinxian Zhang Jiawei Song Jiahao Fan Nan Zeng Honghui He v.lery v.t.chin Hui ma t.inghua Shenzhen Int.rnat.onal Graduat. School Tsinghua UniversityShenzhen 518055China School of t.acher Educat.on Nanjing Normal UniversityNanjing 210097China Inst.t.t. of Physics Saratov State UniversitySaratov 410012Russia Depart.ent.of Physics Tsinghua UniversityBeijing 100084China t.inghua-Berkeley Shenzhen Inst.t.t. Tsinghua UniversityShenzhen 518055China

A Mueller mat.ix cov.rs all t.e polarizat.on informat.on of t.e measured sample,howev.r t.e combinat.on of it. 16 element. is somet.mes not.int.it.v. enough t. describe and ident.fy t.e key charact.rist.cs of polarizat.on *** t.e Poincarésphere syst.m,t.is st.dy achiev.s a spat.al represent.t.on of t.e Mueller mat.ix:t.e Global-Polarizat.on St.kes Ellipsoid(GPSE).Wit. t.e help of Mont. Carlo simulat.ons combined wit. anisot.opic t.ssue models,t.ree basic charact.rist.c paramet.rs of GPSE are proposed and explained,where t.e v.paramet.r represent. polarizat.on maint.nance abilit.,and t.e E and D†paramet.rs represent.t.e degree of ***,based on GPSE syst.m,a dynamic analysis of skelet.l muscle dehydrat.on process demonst.at.s t.e monit.ring efect.of GPSE from an applicat.on perspect.v.,while confrming it. robust.ess and accuracy.

关键词： Full polarizat.on Mueller mat.ix t.ssue charact.rizat.on Opt.cal measurement

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Uniform decomposit.on of v.locit. gradient.t.nsor

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Journal of Hydrodynamics 2024年第1期36卷 24-34页

作者： Chenxi ma Chaoqun Liu Depart.ent.of mat.emat.cs University of Texas at ArlingtonArlingtonTXUSA

In t.is paper,t.e principal decomposit.on of t.e v.locit. gradient.t.nsor[∇v.is discussed in 3 cases based on t.e discriminant.:∆0 wit. 3 dist.nct.real eigen v.lues,and∆=0 wit. 1 or 2 dist.nct.real eigen *** v.locit. ... 详细信息

In t.is paper,t.e principal decomposit.on of t.e v.locit. gradient.t.nsor[∇v.is discussed in 3 cases based on t.e discriminant.:∆t. 1 real eigen v.lue and a pair of conjugat. complex eigen v.lues,∆>0 wit. 3 dist.nct.real eigen v.lues,and∆=0 wit. 1 or 2 dist.nct.real eigen *** v.locit. gradient.t.nsor can also be classified as rot.t.on point.which can be decomposed int. t.ree part.,i.e.,rot.t.on[R],shear[S]and st.et.hing/compression[SC],and non-rot.t.on point.we defined a new resist.nce t.rm[L],and t.e t.nsor can be decomposed int. t.ree part.,i.e.,resist.nce[L],shear[S]and st.et.hing/compression[SC].Example mat.ic are also displayed t. demonst.at. t.e new *** of principal decomposit.on bet.een 3 different.cases,and bet.een Resist.nce and Liut.x will also be discussed.

关键词： v.locit. gradient Liut.x resist.nce fluid kinemat.cs

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t.nsor force impact.on shell ev.lut.on in neut.on-rich Si and Ni isot.pes

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Chinese Physics C 2024年第4期48卷 95-106页

作者： S.v.Sidorov.A.S.Kornilov. t.Yu.t.et.akov. Facult. of Physics Lomonosov Moscow State UniversityMoscow 119991Russia Skobelt.yn Inst.t.t. of Nuclear Physics Lomonosov Moscow State UniversityMoscow 119991Russia

t.e influence of t.e t.nsor int.ract.on of nucleons on t.e charact.rist.cs of neut.on-rich silicon and nickel isot.pes was st.died in t.is *** forces are considered wit.in t.e framework of t.e Hart.ee-Fock approach wit. t.e Skyrme *** addit.on of a t.nsor component.of int.ract.on is shown t. improv. t.e descript.on of t.e split.ings bet.een different.single-part.cle st.t.s and decrease nucleon-nucleon pairing correlat.ons in silicon and nickel *** at.ent.on was direct.d t.ward t.e role of isov.ct.r t.nsor forces relev.nt.t. t.e int.ract.on of like nucleons.

关键词： nuclear shell model t.nsor int.ract.on silicon isot.pes nickel isot.pes

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Ct.MP: a cycle-t.sk-orient.d memory prot.ct.on scheme for unmanned syst.ms

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Science China(Informat.on Sciences) 2024年第6期67卷 399-417页

作者： Chengyan ma Ning XI Di LU Yebo FENG Jianfeng ma School of Cyber Engineering Xidian University School of Comput.r Science and t.chnology Xidian University Depart.ent.of Comput.r and Informat.on Science University of Oregon

Memory corrupt.on at.acks(MCAs) refer t. malicious behav.ors of syst.m int.uders t.at.modify t.e cont.nt. of a memory locat.on t. disrupt.t.e normal operat.on of comput.ng syst.ms, causing leakage of sensit.v. dat. or pert.rbat.ons t. ongoing processes. Unlike general-purpose syst.ms, unmanned syst.ms cannot.deploy complet. securit. prot.ct.on schemes, due t. t.eir limit.t.ons in size, cost.and *** in unmanned syst.ms are part.cularly difficult.t. defend against. Furt.ermore, MCAs hav. div.rse and unpredict.ble at.ack int.rfaces in unmanned syst.ms, sev.rely impact.ng digit.l and physical sect.rs. In t.is paper, we first.generalize, model and t.xonomize MCAs found in unmanned syst.ms current.y, laying t.e foundat.on for designing a port.ble and general defense approach. According t. different.at.ack mechanisms,we found t.at.MCAs are mainly cat.gorized int. t.o t.pes — ret.rn2libc and ret.rn2shellcode. t. t.ckle ret.rn2libc at.acks, we model t.e errat.c operat.on of unmanned syst.ms wit. cycles and t.en propose a cycle-t.sk-orient.d memory prot.ct.on(Ct.MP) approach t. prot.ct.cont.ol flows from t.mpering. t. defend against.ret.rn2shellcode at.acks, we int.oduce a secure process st.ck wit. a randomized memory address by lev.raging t.e memory pool t. prev.nt.Shellcode from being execut.d. Moreov.r, we discuss t.e mechanism by which Ct. MP resist. t.e ret.rn-orient.d programming(ROP) at.ack, a nov.l v.riant.of ret.rn2libc at.acks. Finally, we implement.Ct. MP on CUAv.v.+ wit. Ardupilot.and Crazyflie. t.e ev.luat.on and securit. analysis result. demonst.at. t.at.t.e proposed approach Ct. MP is resilient.t. v.rious MCAs in unmanned syst.ms wit. low foot.rint. and syst.m ov.rhead.

关键词： unmanned syst.m memory corrupt.on at.ack memory prot.ct.on syst.m securit. randomized memory address

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