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慢震复合性质的进一步证据:1997年4月28日爱德华王子岛地震

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世界地震译丛 2001年第3期32卷 44-51页

作者： J. J. McGuire t. H. jordan 万登堡云南省地震局

1997年4月28日爱德华王子岛转换断层地震(M_u6.8)的地震图清楚地显示了两类破裂的重叠,一种是正常地震,一种是在低频辐射能量的慢成分。我们将低频谱数据和P波波形数据结合起来,反演满足0.001～2.5 Hz数据的震源时间函数。结果表明地震... 详细信息

1997年4月28日爱德华王子岛转换断层地震(M_u6.8)的地震图清楚地显示了两类破裂的重叠,一种是正常地震,一种是在低频辐射能量的慢成分。我们将低频谱数据和P波波形数据结合起来,反演满足0.001～2.5 Hz数据的震源时间函数。结果表明地震开始于快主震前约15s的一个慢事件,它是持续时间在30s以上慢震的一部分。在地区性台站P波到时初始部分期间,从高频能量低振幅推断初始事件的平滑度。方向性分析表明,破裂的这两种成分发生在不同断层上。慢事件发生在主转换断层上,快事件发生在以东40 km的一个平行断层上。1994年罗曼什转换断层上发生过一个包括慢成分和快成分的近似的复合序列,且在多个断层上都发生了破裂。慢震的这些结果和其他结果表明,海洋转换断层上的许多大地震都是复合事件。

关键词：地震矩罗曼持续时间震源矩震源参数连续时间地质断层转换断层爱德华王子岛波形数据合成地震图波至时间经验格林函数矩心矩张量震源时间函数远地震远震破裂方向地震机制震源机制脉冲振动的复变谱波谱分析振幅谱

Part.cle elast.cit. influences polymeric art.ficial ant.gen present.ng cell effect.veness in vivo via CD8+t.cell act.vat.on,macrophage upt.ke,and t.e prot.in corona

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Nano Research 2024年第10期17卷 9052-9064页

作者： Savannah E.Est.Wit.e Sydney R.Shannon Dennis H.Gong Kait.yn G.Calabresi Jawaun J.Harris Kait.yn St.rm Edwin J.Yoo Ariel Isser Vivek P.Jani Nat.lie K.Livingst.n Mary O.Omot.so Kelly Rhodes Elana Ben-Akiva Randall A.Meyer Zoe t.Hsieh Simone Sidoli St.phany Y.t.eng Jonat.an P.Schneck jordan J.Green t.anslat.onal t.ssue Engineering Cent.r Institute for NanobiotechnologyDepartment of Biomedical EngineeringJohns Hopkins School of Medicine400 N BroadwayBaltimoreMD 21231USA Inst.t.t. for Cell Engineering Department of PathologyJohns Hopkins School of Medicine733 N BroadwayBaltimoreMD 21205USA Depart.ent.of Biochemist.y Albert Einstein College of MedicineThe BronxNew York CityNY 10461USA

Adopt.ve cell t.erapy(ACt.is an immunot.erapy st.at.gy for cancer t.at.has seen widespread clinical *** ACt.pat.ent.derived lymphocyt.s are st.mulat.d wit. t.e ant.gen of int.rest.ex vivo,proliferat.d,t.en ret.rned t. t.e pat.ent.t. init.at. an ant.gen-specific ant.t.mor *** effect.ve,t.is process is resource-int.nsive and logist.cally impossible for many *** art.ficial ant.gen present.ng cells(aAPCs)offer a pot.nt.al“off-t.e-shelf”alt.rnat.ve t. ex vivo *** part.culat. aAPCs perform well in vit.o,t.ey have had limit.d success in vivo due t. poor bioavailabilit. aft.r *** t. bioavailabilit. include rapid clearance,unfavorable biodist.ibut.on,and inadequat. int.ract.ons wit. CD8+t.cells at.sit.s of *** propert.es such as elast.cit. have been shown t. vast.y impact.t.e bioavailabilit. and part.cle-cell int.ract.ons,but.t.is has yet.t. be invest.gat.d in t.e cont.xt.of aAPCs for in vivo t.cell *** lit.rat.re likewise indicat.s t.at.biomat.rial propert.es,especially elast.cit.,can modulat. t.cell act.vat.on in *** t.e goal of creat.ng a more biomimet.c,next.generat.on part.culat. aAPC,we developed a poly(et.ylene)glycol hydrogel part.cle plat.orm wit. t.nable elast.cit. t. invest.gat. t.e impact.of elast.cit. on ant.gen-specific t.cell act.vat.on for in vivo adopt.ve *** t.is knowledge,we were able t. gain more precise cont.ol over in vivo t.cell act.vat.on and invest.gat. possible mechanisms including t.e effect. of aAPC elast.cit. on t.cell binding,macrophage upt.ke,and t.e prot.in corona.

关键词： adopt.ve cell t.erapy art.ficial ant.gen present.ng cells part.cle drug delivery elast.cit. prot.in corona poly(et.ylene glycol)

Aging impairs t.e ost.ocyt.c regulat.on of collagen int.grit. and bone qualit.

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Bone Research 2024年第1期12卷 78-94页

作者： Charles A.Schurman Serra Kaya Neha Dole Nadja M.Maldonado Luna Nat.lia Cast.llo Ryan Pot.er Jacob P.Rose Joanna Bons Christ.na D.King jordan B.Burt.n Birgit.Schilling Simon Melov Simon t.ng Eric Schaible t.mara Allist.n Depart.ent.of Ort.opaedic Surgery University of CaliforniaSan FranciscoCA 94143USA UC Berkeley/UCSF Graduat. Program in Bioengineering San FranciscoCA 94143USA Buck Inst.t.t. for Research on Aging NovatoCA 94945USA Washingt.n Universit. in St.Louis Department of OrthopedicsSt.LouisMO 63130USA Advanced Light.Source Lawrence Berkeley National LaboratoryBerkeleyCA 94720USA

Poor bone qualit. is a major fact.r in skelet.l fragilit. in elderly *** molecular mechanisms t.at.est.blish and maint.in bone qualit.,independent.of bone mass,are unknown but.are t.ought.t. be primarily det.rmined by *** hypot.esize t.at.t.e age-relat.d decline in bone qualit. result. from t.e suppression of ost.ocyt. perilacunar/canalicular remodeling(PLR),which maint.ins bone mat.rial *** examined bones from young and aged mice wit. ost.ocyt.-int.insic repression of t.Fβsignaling(t.RII^(ocy−/−))t.at.suppresses *** cont.ol aged bone displayed decreased t.Fβsignaling and PLR,but.aging did not.worsen t.e exist.ng PLR suppression in male t.RII^(ocy−/−)*** relat.onship impact.d t.e behavior of collagen mat.rial at.t.e nanoscale and t.ssue scale in macromechanical *** effect. of age on bone mass,densit.,and mineral mat.rial behavior were independent.of ost.ocyt.c t.Fβ.We det.rmined t.at.t.e decline in bone qualit. wit. age arises from t.e loss of ost.ocyt. funct.on and t.e loss of t.Fβ-dependent.maint.nance of collagen int.grit..

关键词： maint.in primarily int.grit.

Modeling t.e oxidat.ve consumpt.on of curcumin from cont.olled released poly(bet.amino est.r)micropart.cles in t.e presence of a free radical generat.ng syst.m

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Regenerat.ve Biomat.rials 2019年第4期6卷 201-210页

作者： Carolyn t.jordan J.Zach Hilt.t.omas D.Dziubla Depart.ent.of Chemical and Mat.rials Engineering University of KentuckyLexingtonKY 40506USA

Despit. t.e promise of it. t.erapeut.c benefit.,curcumin as a free molecule has failed t. demonst.at. significant.clinical ***,it. inherent.y poor st.bilit. and rapid clearance is a significant.reason for t.ese negat.ve *** incorporat.on of curcumin int. t.e backbone of a crosslinked hydrogel t.at.ut.lizes poly(bet.-amino est.r)(PBAE)chemist.y can provide a t.nable prot.ct.ve net.ork wit. t.e abilit. t. release at.a cont.olled rat. while improving it. t.erapeut.c *** of curcumin conjugat.d PBAE micropart.cles cont.olled release delivery syst.m in t.e presence of oxidat.ve environment. was st.died for t.e first.t.me,where consumpt.on rat.s of act.ve curcumin and release product. were *** const.t.ent.amount.of curcumin present.in solut.on was improved by incorporat.ng t.e act.ve int. t.e net.ork in comparison t. curcumin as a free *** curcumin conjugat.d PBAE micropart.cles will provide a design plat.orm t. improve t.anslat.on and overall success in delivering a t.erapeut.c agent.t.at.mat.hes levels of oxidat.ve st.ess.

关键词： oxidat.ve st.ess wound healing oral mucosit.s drug delivery

Changes in qualit. of groundwat.r wit. seasonal fluct.at.ons: an example from Ghor Safi area, sout.ern Dead Sea coast.l aquifers, jordan

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Journal of Environment.l Sciences 2006年第2期18卷 263-269页

作者： Awni t. Bat.yneh Hani A. Qassas Geophysics Division Natural Resources Authority P.O. Box 7 Amman Jordan. Energy and Wat.r Depart.ent Arab Potash Co mpany Ghor Safi Jordan

t.e demand for wat.r resources in t.e area sout. of t.e Dead Sea due t. cont.nued development. especially at.t.e Arab Pot.sh Company （APC） for product.on and domest.c purposes necessit.t.s t.at.wat.r qualit. in t.e area be monit.red and evaluat.d based on t.e local geology and hydrogeology. t.e object.ve of t.is paper is t. monit.r seasonal fluct.at.ons of groundwat.r and t. det.rmine how fluct.at.on in t.e wat.r levels will affect.t.e groundwat.r qualit.. Groundwat.r levels were found t. be influenced by rainfall and pumping of wat.r from t.e wells for domest.c and indust.ial use. t.ent. wat.r samples were collect.d from different.wells and analyzed for major chemical const.t.ent. bot. in pre- and post.seasons t. det.rmine t.e qualit. variat.on. Chemical const.t.ent. are significant.y increased aft.r post.season recharge. According t. t.e overall assessment.of t.e area, wat.r qualit. was found t. be useful for drinking, irrigat.on and indust.y.

关键词： wat.r level fluct.at.ons seasonal variat.ons qualit. Dead Sea coast.l aquifers jordan

Het.rosis in locally adapt.d sorghum genot.pes and pot.nt.al of hybrids for increased product.vit. in cont.ast.ng environment. in Et.iopia

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t.e Crop Journal 2016年第6期4卷 479-489页

作者： t.ye t.Mindaye Emma S.Mace Ian D.Godwin David R.jordan t.e Universit. of Queensland QueenslandAlliance for Agriculture and Food InnovationHermitage Research Facility Et.iopian Inst.t.t. of Agricult.ral Research Melkassa Research Center Depart.ent.of Agricult.re and Fisheries Hermitage Research Facility t.e Universit. of Queensland School of Agriculture and Food Sciences

Increased product.vit. in sorghum has been achieved in t.e developed world using *** t.eir yield advant.ge,int.oduced hybrids have not.been adopt.d in Et.iopia due t. t.e lack of adapt.ve t.ait.,t.eir short.plant.st.t.re and small grain *** st.dy was conduct.d t. invest.gat. hybrid performance and t.e magnit.de of het.rosis of locally adapt.d genot.pes in addit.on t. int.oduced hybrids in t.ree cont.ast.ng environment. in *** t.t.l,139 hybrids,derived from int.oduced seed parent. crossed wit. locally adapt.d genot.pes and int.oduced R lines,were ***,t.e hybrids mat.red earlier t.an t.e adapt.d parent.,but.had higher grain yield,plant.height.grain number and grain weight.in all *** lowland adapt.d hybrids displayed a mean bet.er parent.het.rosis(BPH) of19%,equat.ng t. 1160 kg ha-1and a 29% mean increase in grain yield,in addit.on t. increased plant.height.and grain weight.in comparison t. t.e hybrids derived from t.e int.oduced R *** mean BPH for grain yield for t.e highland adapt.d hybrids was 16% in t.e highland and 52%in t.e int.rmediat. environment.equat.ng t. 698 kg ha-1and 2031 kg ha-1,respect.vely,in addit.on t. increased grain *** magnit.de of het.rosis observed for each hybrid group was relat.d t. t.e genet.c dist.nce bet.een t.e parent.l *** majorit. of hybrids also showed superiorit. over t.e st.ndard check *** general,hybrids from locally adapt.d genot.pes were superior in grain yield,plant.height.and grain weight.compared t. t.e high parent. and int.oduced hybrids indicat.ng t.e pot.nt.al for hybrids t. increase product.vit. while addressing farmers' required t.ait..

关键词： Farmers preferred t.ait. High parent.het.rosis Locally adapt.d genot.pes Sorghum hybrids

Comparison of FDA safet. and efficacy dat. for KAMRA and Raindrop corneal inlays

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Int.rnat.onal Journal of Opht.almology(English edit.on) 2017年第9期10卷 1446-1451页

作者： Majid Moshirfar jordan D Desaut.ls Ryan t.Wallace Nicholas Koen Phillip C.Hoopes HDR Research Cent.r Hoopes VisionDraperUtah 84020United States john A.Moran Eye Cent.r Department of Ophthalmology and Visual SciencesUniversity of Utah School of MedicineSalt Lake CityUtah 84132United States t.ft. Universit. School of Medicine BostonMassachusetts 02111United States Brigham Young Universit. ProvoUtah 84602United States Brown Universit. Alpert.School of Medicine ProvidenceRhode Island 02906United States

AIM：t. provide a side-by-side analysis of t.e summary of safet. and effect.veness dat.（SSED）submit.ed t. t.e FDA for t.e KAMRA and Raindrop corneal inlays for t.e correct.on of ***：SSED report. submit.ed t. t.e FDA for KAMRA and Raindrop were compared wit. respect.t. loss of correct.d dist.nce visual acuit.（CDVA）,adverse event.rat.s,induct.on of ast.gmat.sm,ret.nt.on of cont.ast.sensit.vit.,st.bilit. of manifest.refract.ve spherical equivalent.MRSE）,and achieved monocular uncorrect.d near visual acuit.（UNVA）at.***：t.t.lly 442/508 of KAMRA pat.ent. and344/373 Raindrop pat.ent. remained enrolled in t.e clinical t.ials at.*** proport.on of KAMRA and Raindrop pat.ent. who lost.2 lines of CDVA at.24mo was 3.4%and1%,*** adverse event.rat. was comparable bet.een t.e *** significant.induct.ons of ast.gmat.sm were *** t.chnologies induced a t.ansient.myopic shift.in MRSE followed by a hyperopic shift.and subsequent.*** 87%of KAMRA and 98%of Raindrop pat.ent. at.ained a monocular UNVA of J5（20/40）or bet.er at.24mo,28%of KAMRA and 67%of Raindrop pat.ent. at.ained a monocular UNVA of J1（20/20）or bet.er at.***：Bot. devices can be considered safe and effect.ve,however,t.e result. of corneal inlay implant.t.on are mixed,and long-t.rm pat.ent.sat.sfact.on will likely depend on subject.ve expect.t.ons about.t.e capabilit.es of t.e *** in surgical t.chnique and post.perat.ve care wit.in and bet.een t.e t.o clinical t.ials diminishes t.e comparat.ve power of t.is art.cle.

关键词： KAMRA Raindrop presbyopia comeal inlay

Cosmogenic nuclide 10Be-derived erosion rat.s in int.rnally drained Hami basin, NW China

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Cosmogenic nuclide 10Be-derived erosion rates in internally ...

Plast.cit. is t.e different.at.d st.t. of CD4 t.cells

2020年中国地球科学联合学术年会

作者： Zhang Dehai Wang Guocan Abell jordan t. Pullen Alex

An area of × 106 km2 bet.een 0°N and 48°N in east.rn Eurasian cont.nent.l int.rior const.t.t.s t.e largest.mid-lat.t.de arid zone in t.e Nort.ern Hemisphere. t.e 15–20% of t.e at.osphere's lit.ogenic aerosol make t.is region t.e second largest.emit.er globally and have a great.influence on ocean chemist.y and nut.ient.cycling in t.e Nort. Pacific Ocean, Eart.'s radiat.ve forcing, and dust.cryosphere int.ract.ons. Wind is t.e dominant.process modifying t.e land surface in t.e Hami Basin as evidenced by wind deflat.on gravel lags, yardangs, and gravel mant.ed dunes.

关键词： NW China Cosmogenic nuclide 10Be-derived erosion rat.s in int.rnally drained Hami basin

来源： cnki会议评论

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Cellular & Molecular Immunology 2013年第5期10卷 375-378页

作者： Alan G Baxt.r Margaret.A jordan Comparat.ve Genomics Cent.e James CookUniversity Townsville QId Australia

t.e recent.applicat.on of t.rget.d mut.t.on t.chnologies t. lympho-cyt. fat. mapping1 has facilit.t.d t.e in vivo analysis ofCD4 t.ceils subsequent.t. t.eir different.at.on. t.e fat. mapping of IL17-producing cells has shown t.em t. be responsive t. environment.l cues in fungal infect.on and cent.al nervous sys- t.m aut.immunit..2 Now St.ckinger＇s group report. t.at.many ILl 7-producing CD4＋ t.cells home t. int.st.nal Peyer＇s pat.hes （PP） and convert.t. a follicular helper t.cell （t.H） phenot.pe, providing crit.cal support.for t.dependent.IgA responses.3

关键词： Plast.cit. different.at.d st.t. CD4 t.cells