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Neuroinflammat.on revisit.d t.rough t.e microglial lens

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Neural Regenerat.on Research 2025年第7期20卷 1989-1990页

作者： Renat. Socodat. João b.Relvas Inst.t.t. of Research and Innovat.on in Healt.(i3S)and Inst.t.t. for Molecular and Cell biology(IbMC) University of PortoPortoPortugal Depart.ent.of biomedicine Faculty of Medicine of the University of Porto(FMUP)PortoPortugal

Neuroimmunology is emerging as a pivot.l field,shedding light.on t.e int.icat. dialogues bet.een t.e cent.al nervous syst.m(CNS)and t.e immune *** explorat.on is part.cularly significant.in underst.nding microglia,t.e CNS’s innat. immune cells,beyond t.e convent.onal conflat.on of“neuroinflammat.on”and“microglial act.vat.on.”t.is conflat.on has clouded t.e t.ue complexit. of t.ese processes,pot.nt.ally st.lling scient.fic progress and t.e development.of new *** challenge t.e long-st.nding perspect.ves t.at.have oversimplified t.ese int.ract.ons,advocat.ng for a deeper explorat.on of t.e dynamic relat.onship bet.een neuroinflammat.on and microglial *** dissect.ng specific molecular pat.ways,we aim t. illuminat. t.eir elaborat. roles in neuroinflammat.ry responses,especially in t.e cont.xt.of Alzheimer’s disease(AD).Here,neuroinflammat.on is not.merely a passive observer or a direct.ant.gonist.but.a complex agent.in t.e disease’s *** art.cle calls for a significant.paradigm shift.t.wards an int.grat.ve,mult.-omics approach t. *** such a comprehensive framework is crucial for advancing our underst.nding of neuroinflammat.ry condit.ons and paving t.e way for t.rget.d t.erapeut.c st.at.gies for brain diseases.

关键词： inflammat.on simplified act.vat.on

Suzuki React.on of Aryl bromides Using a Phosphine-Free Magnet.c Nanopart.cle-Support.d Palladium Cat.lyst

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催化学报 2011年第11期32卷 1667-1676页

作者： Nghia t. bUI t.ung b. DANG Ha V. Le Nam t. S. PHAN Depart.ent.of Chemical engineering HCMC University of Technology VNU-HCM 268 Ly Thuong Kiet Distriet 10 Ho Chi Minh City Viet Nam

A palladium cat.lyst.immobilized on superparaganet.c nanopart.cles was prepared wit. a palladium loading of 0.30 mmol/g. t.e cat.lyst.was charact.rized using X-ray diffract.on, scanning elect.on microscopy, t.ansmission elect.on microscopy, vibrat.ng sample magnet.met.y, t.ermogravimet.ic analysis, Fourier t.ansform infrared, at.mic absorpt.on spect.ophot.met.y, and nit.ogen adsorpt.on. t.e immobilized palladium cat.lyst.was an efficient.cat.lyst.wit.out.added phosphine ligands for t.e Suzuki cross-coupling react.on of several aryl bromides wit. phenylboronic acid. t.e recovery of cat.lyst.was simply by magnet.c decant.t.on in t.e presence of a magnet. t.e immobilized palladium cat.lyst.can be reused many t.mes wit.out.significant.degradat.on in cat.lyt.c act.vit.. No leaching of act.ve palladium species int. t.e react.on solut.on was det.ct.d.

关键词： superparamagnet.c nanopart.cle Suzuki react.on palladium aryl bromide

A fully-explicit.discont.nuous Galerkin hydrodynamic model for variably-sat.rat.d porous media

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Journal of Hydrodynamics 2014年第4期26卷 594-607页

作者： De MAet.t. HANeRt.e. VANCLOOSt.R M. eart. and Life Inst.t.t. Environmental SciencesUniversité catholique de LouvainB-1348 Louvain-la-NeuveBelgium Georges Lema?t.e Cent.e for eart. and Climat. Research Université catholique de LouvainB-1348 Louvain-la-NeuveBelgium

Groundwat.r flows play a key role in t.e recharge of aquifers, t.e t.ansport.of solut.s t.rough subsurface syst.ms or t.e cont.ol of surface runoff. Predict.ng t.ese processes requires t.e use of groundwat.r models wit. t.eir applicabilit. direct.y linked t. t.eir accuracy and comput.t.onal efficiency. In t.is paper, we present.a new met.od t. model wat.r dynamics in variably- sat.rat.d porous media. Our model is based on a fully-explicit.discont.nuous-Galerkin formulat.on of t.e 3D Richards equat.on, which shows a perfect.scaling on parallel archit.ct.res. We make use of an adapt.d jump penalt. t.rm for t.e discont.nuous-Galerkin scheme and of a slope limit.r algorit.m t. produce oscillat.on-free exact.y conservat.ve solut.ons. We show t.at.such an approach is part.cularly well suit.d t. infilt.at.on front.. t.e model result. are in good agreement.wit. t.e reference model Hydrus-lD and seem promising for large scale applicat.ons involving a coarse represent.t.on of sat.rat.d soil.

关键词： 3D subsurface flow model discont.nuous Galerkin met.od slope limit.rs explicit.t.me int.grat.on

Inoculat.on wit. Pseudomonas spp. Cont.ining ACC-Deaminase Part.ally eliminat.s t.e effect. of Drought.St.ess on Growt.,Yield,and Ripening of Pea (Pisum sat.vum L.)

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Pedosphere 2008年第5期18卷 611-620页

作者： M. ARSHAD b. SHAHAROONA t. MAHMOOD Inst.t.t. of Soil & environment.l Sciences University of AgricultureFaisalabad-38040(Pakistan) Depart.ent.of Agronomy University of Arid AgricultureRawalpindi(Pakistan)

t.o preselect.d plant.growt. promot.ng rhizobact.ria(PGPR) cont.ining 1-aminocyclopropane-1-carboxylat.(ACC) -deaminase(eC 4.***.99.4) were used t. invest.gat. t.eir pot.nt.al t. ameliorat. t.e effect. of drought.st.ess on growt.,yield,and ripening of pea(Pisum sat.vum L.) . Inoculat.d and uninoculat.d(cont.ol) seeds of pea cult.var 2000 were sown in pot.(four seeds pot.1) and placed in a wire house. t.e plant. were exposed t. drought.st.ess at.different.st.ges of growt.(veget.t.ve,flowering,and pod format.on) by skipping t.e respect.ve irrigat.on. Result. revealed t.at.inoculat.on of peas wit. PGPR cont.ining ACC-deaminase significant.y decreased t.e "drought.st.ess imposed effect." on t.e growt. and yield of peas. exposure of plant. t. drought.st.ess at.veget.t.ve growt. st.ge significant.y decreased shoot.growt. by 41% in t.e case of uninoculat.d plant.,whereas,by only 18% in t.e case of inoculat.d plant. compared t. nonst.essed uninoculat.d cont.ol. Grain yield was decreased when plant. were exposed t. drought.st.ess at.t.e flowering and pod format.on st.ge,but.inoculat.on result.d in bet.er grain yield(up t. 62% and 40% higher,respect.vely) t.an t.e respect.ve uninoculat.d nonst.essed cont.ol. Ripening of pods was also delayed in plant. inoculat.d wit. PGPR,which may imply decreased endogenous et.ylene product.on in inoculat.d plant.. t.is premise is furt.er support.d by t.e observat.on t.at.inoculat.on wit. PGPR reduced t.e int.nsit. of classical "t.iple" response in et.olat.d pea seedlings,caused by ext.rnally applied ACC. It.is very probable t.at.t.e drought.st.ess induced inhibit.ry effect. of et.ylene could be part.ally or complet.ly eliminat.d by inoculat.on wit. PGPR cont.ining ACC-deaminase.

关键词： ACC-deaminase drought.st.ess plant.growt. rhizobact.ria ripening

η-product.on on t.e prot.n via elect.omagnet.c and hadronic probes

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Chinese Physics C 2009年第12期33卷 1175-1182页

作者： b. Saghai J. Durand b. Julia-Diaz 何军 t.-S. H. Lee t. Sat. Inst.t.t.de Recheche sur les lois Fondament.les de l’Univers DSM/Irfu CEA-Saclay 91191 Gif-sur-Yvette France 2. Excited Baryon Analysis Center (EBAC) Thomas Jefferson National Accelerator Facility Newport News Virginia 22901 USA 3. Departament d'Estructura i Constituents de la Matèria and Institut de Ciències del Cosmos Universitat de Barcelona E-08028 Barcelona Spain 4. Institute of Modern Physics Chinese Academy of Sciences Physics Division Argonne National Laboratory Argonne Illinois 60439 USA Depart.ent.of Physics Osaka University Toyonaka Osaka 560-0043 Japan

t.e react.ons π-p→ηn and γp→ηp are invest.gat.d wit.in a dynamical coupled-channels model of meson product.on react.ons in t.e nucleon resonance region. t.e meson-baryon channels included are πN, ηN, π-, σN, and ρN. t.e direct.η-phot.product.on process is st.died wit.in a formalism based on a chiral const.t.ent.quark model approach, complement.d wit. a one-gluon-exchange mechanism, t. t.ke int. account.t.e breakdown of t.e SU(6)O(3) symmet.y. In t.e models search, t.e following known nucleon resonances are embodied: S11(1535), S11(1650), P11(1440), P11(1710), P13(1720), D13(1520), D13(1700), D15(1675), and F15(1680). Dat. for t.e π-p→ηn react.on from t.reshold up t. a t.t.l cent.r-of-mass energy of W ≈ 2 GeV are sat.sfact.rily reproduced. For t.e phot.product.on channel, t.o addit.onal higher mass known resonances, P13(1900) and F15(2000), are also considered. However, reproducing t.e dat. for γp→ηp requires, wit.in our approach, t.o new nucleon resonances, for which we ext.act.mass and widt..

关键词： Part.cle physics and field t.eory

Lysozyme as an alt.rnat.ve t. growt. promot.ng ant.biot.cs in swine product.on

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Journal of Animal Science and biot.chnology 2016年第1期7卷 34-40页

作者： W. t. Oliver J.e.Wells USDA ARS U.S. Meat Animal Research Center P. O. Box 166 Clay Center NE68933-0166 USA

Lysozyme is a nat.rally occurring enzyme found in bodily secret.ons such as t.ars, saliva, and milk. It.funct.ons as an ant.microbial agent.by cleaving t.e pept.doglycan component.of bact.rial cell walls, which leads t. cell deat.. Ant.biot.cs are also ant.microbials and have been fed at.subt.erapeut.c levels t. swine as growt. promot.rs. t.ese compounds benefit.swine producers by minimizing product.on losses by increasing feed efficiency and decreasing suscept.bilit. t. bact.rial infect.on and disease. t.is manuscript.reviews t.e knowledge of t.e effect. of lysozyme, as compared t. t.adit.onal subt.erapeut.c ant.biot.cs in swine feed, on pig performance and healt.. It.is clear from decades of st.dies t.at.ant.biot.c use in feeds increases pig performance, part.cularly in t.e nursery. Similarly, lysozyme, as a feed addit.ve, increases growt. and feed efficiency. While t.e mechanism by which ant.biot.cs and lysozyme improve performance is not.clearly underst.od, bot. of t.ese feed addit.ves improve gast.oint.st.nal healt., improve t.e met.bolic profile, and alt.r t.e gast.oint.st.nal bact.ria ecology of swine. t.erefore, lysozyme is a suit.ble alt.rnat.ve t. growt.-promot.ng subt.erapeut.c ant.biot.c use in swine feed.

关键词： Ant.biot.cs Gast.oint.st.nal Lysozyme Microbiot. Review Swine

effect.of bagasse ash reinforcement.on t.e wear behaviour of Al-Cu-Mg/bagasse ash part.culat. composit.s

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Act. Met.llurgica Sinica(english Let.ers) 2010年第2期23卷 81-89页

作者： V.S. Aigbodion S.b. Hassan G.b. Nyior t. Ause Depart.ent.of Met.llurgical and Mat.rials engineering Ahmadu Bello University

t.e effect.of bagasse ash （bAp） part.cle reinforcement.on t.e wear behavior of Al-Cu- Mg alloy has been st.died. bagasse ash part.cles were varied from 0 wt.pct.10 wt.pct.wit. int.rval of 2 wt.pct. Unlubricat.d pin-on disc t.st. were conduct.d t. examine t.e wear behaviour of t.e aluminium alloy/bagasse ash part.culat. composit.s. t.e t.st. were conduct.d at.varying loads, from 5 t. 20 N and sliding speeds of 1.26 m/s, 2.51 m/s, 3.77 m/s and 5.02 m/s for a const.nt.sliding dist.nce of 5000 m. t.e result. showed t.at.t.e wear rat.s of t.e A1-Cu-Mg/bAp composit.s are lower t.an t.at.of t.e mat.ix alloy and furt.er decrease wit. increasing bagasse ash cont.nt. Wear rat. increases as t.e sliding speed and applied load increase. t.e microst.uct.re of t.e worn surface revealed t.at.a large amount.of plast.c deformat.on appeared on t.e surface of t.e unreinforced alloy. While bagasse ash reinforced Al-Cu-Mg alloy showed worn out.surface t.at.is not.smoot., and grooves, scrat.hes and parallel lines were observed. A combinat.on of adhesion and delaminat.on wear was in operat.on. t.ese result. show t.at.improve wear propert.es is achievable for t.e aluminium alloy by t.e addit.on of bagasse ash part.cles as reinforcement.mat.rial.

关键词： Al-Cu-Mg alloy bagasse ash Composit.s Load Sliding speed and Wear

Combined effect. of rot.t.on and t.ermal radiat.on on perist.lt.c t.ansport.of Jeffrey fluid

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Int.rnat.onal Journal of biomat.emat.cs 2015年第5期8卷 159-179页

作者： t. Hayat.Maimona Rafiq b. Ahmad Depart.ent.of Mat.emat.cs Quaid-i-Azam University 45320 Islamabad44000 Pakistan Nonlinear Analysis and Applied Mat.emat.cs (NAAM) Research Group Depart.ent.of Mat.emat.cs King Abdulaziz University Jeddah 21589 Saudi Arabia

t.e object.ve of t.is communicat.on is t. examine t.e effect.of rot.t.on on t.e perist.lt.c mot.on of non-Newt.nian fluid. Const.t.t.ve relat.onship of Jeffrey fluid is employed in t.e mat.emat.cal formulat.on and relat.d analysis. t.e t.ermal radiat.on and Joule heat.ng effect. are also considered. An elect.ically conduct.ng fluid in a channel wit. compliant.boundaries is t.ken. Solut.on expressions are est.blished t.rough assumpt.ons of large wavelengt. and low Reynolds number. Impact.of t.ylor and Hart.an numbers on t.e axial velocit. is similar in a qualit.t.ve sense. t.ere is reverse effect.of t.ylor number on t.e secondary velocit. when compared wit. t.e axial velocit.. t.mperat.re and heat.t.ansfer coefficient. are increasing funct.ons of t.ylor number.

关键词： Rot.t.ng frame t.ermal radiat.on Joule heat.ng Jeffrey fluid.

Mit.gat.on of eDFA t.ansient.effect. in variable dut. cycle pulsed signals

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Defence t.chnology（防务技术） 2019年第3期15卷 276-281页

作者： D. Meena K.t. Sarat. Fredy Francis e. Dipin t. Srinivas elect.onics and Radar Development.est.blishment.(LRDe) DRDO Bangalore Karnataka 560093 India Model engineering College Thrikkakara Cochin Kerala 682021 India Indian Inst.t.t. of t.chnology Madras Chennai Tamil Nadu 600036 India

We report.t.e t.ansient.effect. in erbium Doped Fiber Amplifier (eDFA) syst.ms for pulsed signals wit. different.dut.-cycles. t.e work includes t.e analysis using t.ree different.dut.-cycles, 10%, 20% and 50%. A curve fit.ing t.chnique is also proposed t. predict.t.e t.ansient. of any lesser dut.-cycled pulse, once t.e t.ansient. of a larger dut.-cycled pulse is known. Mat.emat.cal evaluat.on confirms t.e double exponent.al shape of t.ansient.dist.rt.d signal. Furt.er, eDFA t.ansient.effect.is experiment.lly verified on a Wavelengt. Division Mult.plexed (WDM) link by mult.plexing high and low bit.at. modulat.d opt.cal signals. We conclude t.e paper by proposing a t.ansient.suppression t.chnique for variable dut.cycle signals and analyzing it. effect.veness wit. different.wavelengt. spacing.

关键词： eDFA t.ansient. WDM Variable dut. cycle Suppression