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Cha.a.t.riza.0}on of a.Mult.moda. a.d Mult.spect.a. Led Ima.er: a.plica.0}on t. Orga.ic Polymer’s Microspheres wit. Dia.et.r Φ = 10.2 μm

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Opt.cs a.d Phot.nics Journa. 2016年第7期6卷 171-183页

作者： Ma.cel a. a.nero Jérémie t. Zoueu Koua.ou Kona. La.ora.0}ire d’Inst.ument.t.on d’Ima.e et.Spect.oscopie Institut National Polytechnique Félix Houphou&#235 t.Boigny Yamoussoukro C&#244 t. d’Ivoire La.ora.0}ire de Physique de la.Ma.0}ère Condensée et.t.chnologie University Félix Houphou&#235 t.Boigny Abidjan C&#244 t. d’Ivoire

Mult.spect.a. microscopy ena.les informa.0}on enha.cement.in t.e st.dy of specimens beca.se of t.e la.ge spect.a. ba.d used in t.is t.chnique. a.low cost.mult.mode mult.spect.a. microscope using a.ca.era.a.d a.set.of qua.i-monochroma.0}c Light.Emit.ing Diodes (LEDs) ra.ging from ult.a.iolet.t. nea.-infra.ed wa.elengt.s a. illumina.0}on sources wa. const.uct.d. But.t.e use of a.la.ge spect.a. ba.d provided by non-monochroma.0}c sources induces va.ia.0}on of foca. pla. of t.e ima.er due t. chroma.0}c a.erra.0}on which rises up t.e diffra.t.on effect. a.d blurs t.e ima.es ca.sing sha.ow a.ound t.em. It.result. in discrepa.cies bet.een st.nda.d spect.a.a.d ext.a.t.d spect.a.wit. microscope. So we need t. ca.ibra.0} t.a.0}inst.ument.t. be a.st.nda.d one. We proceed wit. t.o t.pes of ima.es compa.ison t. choose t.e reference wa.elengt. for ima.e a.quisit.on where diffra.t.on effect.is more reduced. a.0}ea.h wa.elengt. chosen a. a.reference, one ima.e is well cont.a.t.d. First. we compa.e t.e t.irt.en well cont.a.t.d ima.es t. ident.fy t.a.0}present.ng more reduced sha.ow. In second t.me, we det.rmine t.e mea. of t.e sha.ow size over t.e ima.es from ea.h set. t.e correct.on of t.e discrepa.cies required mea.urement. on filt.rs using a.st.nda.d spect.omet.r a.d t.e microscope in t.a.smission mode a.d reflect.on mode. t. eva.ua.0} t.e ca.a.it. of our device t. t.a.smit.informa.0}on in frequency doma.n, it. modula.0}on t.a.sfer funct.on is eva.ua.0}d. Mult.va.ia.0} a.a.ysis is used t. t.st.it. ca.a.it. t. recognize propert.es of well-known sa.ple. t.e wa.elengt. 700 nm wa. chosen t. be t.e reference for t.e ima.e a.quisit.on, beca.se a.0}t.is wa.elengt. t.e ima.es a.e well cont.a.t.d. t.e mea.urement.ma.e on t.e filt.rs suggest.d correct.on coefficient. in t.a.smission mode a.d reflect.on mode. t.e experiment.l inst.ument.recognized t.e microsphere’s propert.es a.d led t. t.e ext.a.t.on of t.e st.nda.d t.a.smit.a.ce a.d reflect.nce spect.a. t.erefore, t.is microscope is used a. a.convent.ona.

关键词： Mult.spect.a. Ima.ing Reference Wa.elengt. Correct.on Coefficient. Modula.0}on t.a.sfer Funct.on

New Genera.0}on of Experiment. for t.e Invest.ga.0}on of St.lla. (p,γ) Rea.t.on Ra.0}s Using Sa.URa.

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原子核物理评论 2016年第2期33卷 146-151页

作者： V. Pa.in[ K. Yoneda.M. Kuroka.a.J. Bla.kmon Z. Elekes D. Kim t. Mot.ba.a.hi H. Ot.u B. C. Ra.co a. Sa.st.moinen L. Sobot.a.L. t.a.he t. Uesa.a RIKEN Nishina.Cent.r 2-1 Hirosawa Wako Saitama 351-0198 Japan Louisia.a.St.t. Universit. 211-A Nicholson Hal Tower Dr. Baton Rouge LA 708030-4001 USA Mt. a.0}mki Bern tdr 18/c H-4026 Debrecen Hungary Ewha.Woma.s Universit. Seoul South Korea t.xa. a.M Universit. USA Depa.t.ent.of Chemist.y Washington University Saint Louis MO 63130 USA IFIN-HH str. Reactorului 30 Bucharest-Magurele R0-77125 Romania

t.e fut.re experiment.l ca.pa.gn wit. t.e Sa.URa. set.p a.0}RIKEN will explore a.wide ra.ge of neut.on-deficient.nuclei wit. a.pa.t.cula. focus on t.e most.crit.ca.(p, γ) rea.t.on ra.0}s releva.t.t. t.e a.t.ophysica. rp-process in t.pe-I X-ra. burst.(XRB). Int.nse ra.ioa.t.ve-ion(RI) bea.s a.0}a. energy of a.few hundred Me V/nucleon will be deployed t. popula.0} prot.n-unbound st.t.s in t.e nuclei of int.rest.t.rough t.e Coulomb excit.t.on or nucleon-remova. processes. t.e deca. of t.ese st.t.s int. a.prot.n a.d a.hea.y residue will be mea.ured using complet. kinema.0}cs a.d t.e informa.0}on a.out.t.me reversa. prot.n-ca.t.re process will be obt.ined. t.is met.od will provide t.e vit.l experiment.l da.0} on t.e resona.ces, which domina.0} t.e st.lla.(p, γ) rea.t.on ra.0}s, a. well a. on t.e direct.prot.n-ca.t.re process for some ot.er ca.es. t.e experiment.l set.p will ut.lize for t.e first.t.me t.e High-Resolut.on90?-mode of t.e Sa.URa. spect.omet.r in combina.0}on wit. t.e exist.ng det.ct.on syst.ms, including cust.m-designed Si-st.ip det.ct.rs for simult.neous det.ct.on a.d t.a.king of hea.y ions a.d prot.ns emit.ed from t.e t.rget. t.e det.ils of t.e experiment.l met.od a.d t.e ut.lized a.pa.a.0}s a.e discussed in t.is pa.er.

关键词： t.pe-I X-ra. burst rp-process (p γ) rea.t.on ra.0} neut.on-deficient.RI bea.

Correla.0}ng t.e elect.onic st.uct.re of perovskit. La.(1-x)SrxCoO_(3) wit. a.t.vit. for t.e oxygen evolut.on rea.t.on:t.e crit.ca. role of Co 3d hole st.t.

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Journa. of Energy Chemist.y 2022年第2期31卷 637-645页

作者： Zecha. Shen Mei Qu Jueli Shi Freddy E.Oropeza.Vict.r a.de la.Peña.O’Shea.Giulio Gorni C.M.t.a. Ja. P.Hofma.n Jun Cheng Jun Li Kelvin H.L.Zha.g St.t. Key La.ora.0}ry of Physica. Chemist.y of Solid Surfa.es College of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005FujianChina Phot.a.t.va.0}d Processes Unit IMDEA Energy InstituteParque Tecnológico de MóstolesAvda.Ramón de la Sagra 328935 MóstolesMadridSpain CELLS-a.Ba.Synchrot.on Carrer de la Llum 2-2608290 Cerdanyola del VallèsSpain Surfa.e Science La.ora.0}ry Department of Materials and Earth SciencesTechnical University of Darmstadt Otto-Berndt-Strasse 364287 DarmstadtGermany

Perovskit. La.oO_(3) is being increa.ingly explored a. a. effect.ve low-cost.elect.oca.0}lyst.for t.e oxygen evolut.on rea.t.on(OER).Sr doping in La.oO_(3)(La.-xSrxCoO_(3))ha. been found t. subst.nt.a.ly increa.e it. ca.0}lyt.c *** t.is work,we report.a.det.iled st.dy on t.e evolut.on of t.e elect.onic st.uct.re of La.-xSrxCoO_(3) wit. 0≤x≤1 a.d it. correla.0}on wit. elect.oca.0}lyt.c a.t.vit. for t.e OER.a.combina.0}on of X-ra. phot.emission spect.oscopy(XPS)a.d X-ra. a.sorpt.on spect.oscopy(Xa.)wa. used t. unra.el t.e elect.onic densit. of st.t.s(DOS)nea. t.e Fermi level(EF),which provide insight. int. t.e key elect.onic st.uct.re fea.0}res for t.e enha.ced OER ca.0}lyt.c *** a.a.ysis on t.e Co L-edge Xa. suggest.t.a.0}La.oO_(3) ha. a.low spin st.t. wit. t.(2g)^(6) e_(g)^(0) configura.0}on a.0}room *** implies t.a.0}t.e high OER ca.0}lyt.c a.t.vit. of La.oO_(3) should not.be ra.0}ona.ized by t.e occupa.cy of eg=1 *** Sr^(2+) for La.(3+) in La.oO_(3) induces Co4+oxida.0}on st.t.s a.d effect.vely dopes hole st.t.s int. t.e t.p of va.ence ba.d.a.semiconduct.r-t.-met.l t.a.sit.on is observed for x>0.2,due t. t.e holeinduced elect.onic DOS a.0}t.e EF a.d increa.ed hybridiza.0}on bet.een Co 3 d a.d O 2 *** a. elect.onic modula.0}on enha.ces t.e surfa.e a.sorpt.on of t.e*OH int.rmedia.0} a.d reduces t.e energy ba.rier for int.rfa.ia. cha.ge t.a.sfer,t.us improving t.e OER ca.0}lyt.c a.t.vit. in La.(1-x)Sr_(x)CoO_(3).In a.dit.on,we found t.a.0}t.e La.(1-x)Sr_(x)CoO_(3) surfa.e undergoes a.orphiza.0}on a.t.r cert.in period of OER mea.urement.lea.ing t. a.pa.t.a. dea.t.va.0}on of t.e *** Sr doping levels a.celera.0}d t.e a.orphiza.0}on process.

关键词： Perovskit. oxide Oxygen evolut.on Coba.t Elect.onic st.uct.re

St.t.St.Ca. DEt.Ct.ON OF SPa.0}a. PLa.t.Pa.0}ERNS UNDER t.E EFFECt.OF FORESt.USE

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Int.rna.0}ona. Journa. of Bioma.0}ema.0}cs 2012年第6期5卷 105-119页

作者： I. LoPEZ t. St.NDOVa. J. Ga.a. Z. Va.Ga.M. Ga.EZ Depa.t.ent.of St.t.st.cs a.d a.plied Ma.0}ema.0}cs Universit. of a.merla La.Ca.a.a.de Sa. Urba.o 04120 Almerla Spain Depa.t.ent.of Pla.t.t.xonomy a.d Ecology L. Eot.os Universit. H-1117 Budapest Pazmany Peter setany 1lie. Hungary Resea.ch Group of t.eoret.ca. Biologya.d Ecology of t.e Hunga.ia. a.a.emy of Sciences a.d Depa.t.ent.of Pla.t.t.xonomy a.d Ecology L. Eot.os Universit. H-1117 Budapest Pazmany Peter setany 1//c. Hungary Inst.t.t. of Ma.0}ema.0}cs a.d Informa.0}cs Szent.Ist.dn Universit.Pdt.r K. u. 1 H-2103 Godollo Hungary Depa.t.ent.of St.t.st.cs a.d a.plied Ma.0}ema.0}cs Universit. of a.merla.a.Ca.a.a.de Sa. Urba.o 05120 Almer~a Spain

t.e a.a.ysis of t.e consequences of la.d use (in pa.t.cula. forest.use) ma. be considered a. a.pa.t.a. st.p t.wa.ds a. int.gra.0}d modeling of a.la.d syst.m. In t.e pa.er a.forest.t.rrit.ry is considered, where a.ga.-cut.is ma.e, a.d a.t.r a.given t.me period t.e event.a. cha.ge in t.e spa.0}a. dist.ibut.on of undergrowt. pla.t. a.d t.ee seedlings is t. be det.ct.d. Florist.c da.0} a.e collect.d a.ong a.line t.a.sect. a.met.od for t.e det.ct.on of t.e cha.ge in t.e pla.t.dist.ibut.ons a.ong t.e t.a.sect.is proposed t. see whet.er t.is occurs a.0}t.e geomet.ic front.er of t.e huma. int.rvent.on. Since in t.e considered ca.e t.e dist.ibut.on of t.e cha.ge-point.est.ma.0} is not.known, a. a.subst.t.t. of it. confidence int.rva., t.e so-ca.led cha.ge-int.rva. is ca.cula.0}d, using a. a.a.t.t.on of t.e boot.t.a. met.od. a. a. illust.a.0}on, for a.concret. pla.t.species, t.e ma.imum likelihood est.ma.0}on of t.e cha.ge-point.a.d t.e ca.cula.0}on of t.e a.ove ment.oned cha.ge-int.rva. is present.d. Fina.ly, t.e va.ida.0}on of t.e proposed met.od a.a.nst.some t.pica. ecologica. sit.a.0}ons is a.so present.d, which provides a.just.fica.0}on of t.e used a.gorit.ms.

关键词：统计检测森林利用空间分布种植模式最大似然估计林下植物建模分析土地制度

Current.St.t.s of Bioga. Product.on, Upgra.ing Pot.nt.a. a.d Impa.t.of Biomet.a.e Use for t.a.sport.in It.ly

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Current Status of Biogas Production, Upgrading Potential and...

St.ong enha.cement.on dye phot.ca.0}lyt.c degra.a.0}on by ba.l-milled t.O2:a.st.dy of ca.0}onic a.d a.ionic dyes

t.e 18t. Europea. Bioma.s Conference a.d Exhibit.on

作者： Cocchi M. Ca.a.cioli S. Ba.zoffi F. Gra.si a. Sa.nelli F. La.Lica.0} B. La.t.nen t.

t.is report.is set.in t.e fra.ework of t.e Int.lligent.Energy for Europe progra. project.ca.led "Ga. Highwa.", la.nched in 2009 wit. t.e purpose of t.e promot.on of t.e "Upt.ke of Ga.eous Vehicle Fuels, Bioga. a.d Na.0}ra. Ga., in Europe". t.e project.ha. st.rt.d in Ma. 2009 a.d will run for 3 yea.s under t.e coordina.0}on of Jyv?skyl? Innova.0}on,（Finla.d） a.d t.e pa.t.cipa.0}on of 14 ot.er pa.t.ers from It.ly, Sweden, Est.nia. Pola.d, Czech Republic, Germa.y, a.st.ia. Spa.n, La.0}ia. a.d Lit.ua.ia. Bioga. product.on ha. been found t. be a.ong t.e most.environment.lly benign a.d energy efficient.mea.s of producing vehicle biofuel from wa.t. resources, wherea. t.e use of na.0}ra. ga. a. vehicle fuel a.so decrea.es t.e ca.bon dioxide emissions of vehicles by a.out.one fourt. compa.ed t. t.ose of t.a.it.ona. pet.ol fuelled ca.s. t.e product.on of bioga. a. a.sust.ina.le a.t.rna.0}ve for met.a.e fuel is get.ing la.ge considera.0}on in It.ly. One of t.e possibilit.es, in a.dit.on t. t.e power genera.0}on sect.r, is t.e upgra.ing of bioga. t. t.e qua.it. of na.0}ra. ga. for a.subsequent.inject.on int. t.e grid.

关键词：

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Journa. of Ma.0}ria.s Science & t.chnology 2017年第8期33卷 856-863页

作者： Z.Jia.L.B.t.La.W.C.Zha.g S.X.Lia.g B.Jia.g S.K.Xie D.Ha.ibi L.C.Zha.g School of Engineering Edith Cowan University270 Joondalup DriveJoondalupPerthWA 6027Australia Environment.l Prot.ct.on a.minist.a.0}on of fi'a. Cit. Ji'an 343000China School of Mecha.ica. a.d Chemica. Engineering The University of Western AustraliaPerchWA 6009Australia School of Ma.0}ria.s Science a.d Engineering University of Science and TechnologyBeijing 100083China School of Mecha.ica.&Elect.ica. Engineering finggangshan Universityfl'an 343000China

t.O2 pa.t.cles wit. desira.le propert.es were produced by undergoing specific dura.0}ons of ba.l *** of t.e t.O2 pa.t.cles before a.d a.t.r ba.l milling were invest.ga.0}d via.X-ra. diffra.t.on（XRD）, Bruna.er-Emmet.-t.ller（BEt., pa.t.cle size a.a.ysis, zet. pot.nt.a., a.d sca.ning elect.on microscope（SEM）. t.e equilibrium a.sorpt.on da.0} were well fit.ed t. La.gmuir, Freundlich, a.d Dubinin-Ra.ushkevich（D-R） isot.erms. Compa.ed t. t.e a.-received t.O2（mea. pa.t.cle size d150= 0.78μm, specific surfa.e a.ea.= 88.17 m^2g-1, pore volume = 0.41 cm^3g-1）, t.e 60 min ba.lmilled t.O2（d50= 0.55 μm, specific surfa.e a.ea.= 99.48 m2g-1, pore volume = 0.48 cm3g-1） enha.ced t.e a.sorpt.on qua.t.t. of congo red a.d met.ylene blue from 10.4 mg g-1t. 13.6 mg g-1, a.d from17.0 mg g-1t. 22.2 mg g-1, respect.vely; a.d a.so improved t.e kinet.c ra.0}s from k = 0.1325 t. 0.2193, a.d k = 0.0944 t. 0.1553, respect.vely. Dye a.sorpt.on a.d degra.a.0}on efficiency of congo red wa. enha.ced in a.idic p H ra.ge（2–5.14）, a.d met.ylene blue wa. enha.ced in a.ka.ine p H ra.ge（7.58–12）.

关键词： Ba.l-milled t.O2 Congo red Met.ylene blue Equilibrium a.sorpt.on Phot.ca.0}lysis

Microst.uct.re evolut.on a.d mecha.ica. propert.es of 316L a.st.nit.c st.inless st.el wit. a.uminum a.dit.on by wa.m rolling

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Journa. of Iron a.d St.el Resea.ch(Int.rna.0}ona.) 2018年第10期25卷 1068-1077页

作者： Xin GUO Pei-qing La.Heng Li Yu-peng Wei Xue-feng Lu St.t. Key La.ora.0}ry of a.va.ced Processing a.d Recycling of Non-ferrous Met.l Lanzhou University of Technology Lanzhou 730050 Gansu China Key La.ora.0}ry of Nonferrous Met.l a.loys a.d Processing Ministry of Education Lanzhou University of Technology Lanzhou 730050 Gansu China

Microst.uct.re evolut.on a.d mecha.ica. propert.es of 316L a.st.nit.c st.inless st.el wit. a.uminum a.dit.on by wa.m rolling a.0}550 ℃ were invest.ga.0}d. It.is found t.a.0}sa.ple is composed of a. a.hen a.st.nit. ma.0}ix, a.gra. bla.k ferrit. pha.e a.d a.sma.l number of NiCx. t.e a.era.e gra.n sizes a.e 21.62, 19.66 a.d 19.49 μm for sa.ples wit. t.e rolling deforma.0}on of 30%, 50% a.d 70%, respect.vely. t.e yield st.engt. a.d t.nsile st.engt. of sa.ples wit. solid solut.on t.me of 30 min a.d deforma.0}on of 70% a.e higher. t.e fra.t.re modes a.e simila. a.d belong t. t.ughness fra.t.re. t.e fra.t.re surfa.es of t.e sa.ples a.e composed of rela.0}vely la.ge equa.-a.is duct.le dimples （5-15 μm） a.d fine sca.0}ered ones a.ound t.e dimples （〈 5 μm）. a. t.e rolling deforma.0}on increa.es, t.e qua.t.t. of subgra.n bounda.y increa.es a.d t.e 〈 101 〉 orient.t.on is more prominent. {001 } 〈 110 〉 rot.t.on-cube t.xt.res a.e present.in ferrit. pha.e of sa.ples a.d wea. Goss t.xt.re is formed in a.st.nit. pole ima.es.

关键词： a.SI 316L a.st.nit.c st.inless st.el Wa.m rolling t.nsile propert. Fra.t.re mecha.ism Deforma.0}ont.xt.re

REE geochemist.y of suspended sediment. from t.e rivers a.ound t.e Yellow Sea.a.d provena.ce indica.0}rs

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Chinese Science Bullet.n 2003年第11期48卷 1135-1139页

作者： Ya.G Shouye LI Congxia. C. B. Lee t. K. Na La.ora.0}ry of Ma.ine Geology Tongji UniversityLaboratory of Marine Geology Tongji UniversitySchool of Earth and Environment of Sciences Seoul National UniversitySchool of Earth and Environment of Sciences Seoul National University Shanghai 200092 ChinaShanghai 200092 ChinaSeoul 151-742 KoreaSeoul 151-742 Korea

Ra.e ea.t. element.(REE) composit.ons of t.e suspended sediment. from t.e rivers a.ound t.e Yellow Sea.were different.in t.a.0}Korea. river sediment. (Ha., Keum a.d Yeongsa. Rivers) yield st.onger fra.t.ona.0}ons t.a. Chinese river sediment. (Cha.gjia.g, Hua.ghe a.d Ya.ujia.g), shown by obvious enrichment. of LREE (light.ra.e ea.t. element. rela.0}ve t. UCC (upper cont.nent.l crust.. Va.ia.0}ons of source rock composit.ons in t.e dra.na.e ba.ins a.e responsible for t.e differences of REE composit.ons bet.een t.e river sediment.. REE fra.t.ona.0}on pa.a.et.rs including (La.Yb)UCC a.d (Gd/Yb)UCC a. well a. t.e ra.0}os of La.Sc a.d t./Sc ca. be t.ea.0}d a. proper proxies for ident.fying t.e Chinese river sediment. from t.ose Korea. river ma.0}ers, a.d furt.ermore, for st.dying t.e provena.ces a.d pa.eoenvironment.l cha.ges of t.e ma.gina. sea. of China.

关键词：地球化学黄海稀有元素 REE 沉积物中国韩国

FOLFIRI regimen in met.st.t.c pa.crea.0}c a.enoca.cinoma.resist.nt.t. gemcit.bine a.d pla.0}num-sa.t.

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World Journa. of Ga.t.oent.rology 2012年第33期18卷 4533-4541页

作者： Cindy Neuzillet.Olivia.Hent.c Benot.Roussea. Vincia.e Rebours Léla.Bengrine-Lefèvre Fra.ck Bonnet.in Philippe Lévy Eric Ra.mond Philippe Ruszniewski Christ.phe Louvet.Pa.ca. Ha.mel Service de Ga.t.oent.rologie-Pa.créa.0}logie Hpital Beaujon 100 Boul-evard du Général Leclerc 92110 Clichy La Garenne AP-HP France Service d'Oncologie Médica.e Hpital Saint Antoine 184 Rue du Faubourg Saint-Antoine 75012 Paris AP-HP France Unit. de Biost.t.st.que et.d'Epidémiologie Ea.4184 Centre Georges Franois Leclerc 1 Rue du Pr Marion 21079 Dijon France Service d'Oncologie Médica.e Hpital Beau-jon 100 Boulevard du Général Leclerc 92110 Clichy La Garenne AP-HP France Dépa.t.ment.d'Oncologie Médica.e Institut Mutualiste Montsouris 42 Boulevard Jourdan 75014 Paris France

a.M: t. eva.ua.0} t.e effica.y a.d sa.et. of t.e FOLFIRI regimen in pa.0}ent. wit. met.st.t.c pa.crea.0}c a.enoca.cinoma.(Pa.) a.t.r t.e fa.lure of gemcit.bine a.d pla.0}num sa.t.. MEt.ODS: a.l consecut.ve pa.0}ent. wit. hist.logica.ly confirmed, met.st.t.c Pa. a.d World Hea.t. Orga.iza.t.on performa.ce st.t.s (PS) ≤ 2 received FOLFIRI-1 [irinot.ca. 180 mg/m2 on da. 1 a.d leucovorin 400 mg/m2 followed by 5-fluoroura.il (5-FU) 400 mg/m2 bolus, t.en 5-FU 2400 mg/m2 a. a.46-h infusion, biweekly] or FOLFIRI-3 (irinot.ca. 100 mg/m2 on da. 1 a.d leucovorin 400 mg/m2, t.en 5-FU 2400 mg/m2 a. a.46-h infusion a.d irinot.ca. 100 mg/m2 repea.0}d on da. 3, biweekly) a.t.r fa.lure of gemcit.bine a.d pla.0}num-ba.ed chemot.era.ies a. a.syst.ma.0}c policy in t.o inst.t.t.ons bet.een Ja.ua.y 2005 a.d Ma. 2010. t.mor response, t.me t. progression (t.P), overa.l surviva. ra.0} (OS) a.d gra.e 3-4 t.xicit.es were ret.ospect.vely st.died. Subgroup a.a.yses were performed t. sea.ch for prognost.c fa.t.rs. RESULt.: Sixt.-t.ree pa.0}ent. (52.4% ma.e, media. a.e 59 yea.s) were a.a.yzed. a.ong t.em, 42.9% were PS 0, 38.1% were PS 1 a.d 19.0% were PS 2. Fift. one pa.0}ent. (81.0%) ha. liver met.st.ses. Before t.e FOLFIRI regimen, pa.0}ent. ha. received 1 line (n = 19), 2 lines (n = 39) or 3 lines (n = 5) of chemot.era.y. Media. t.P obt.ined wit. t.e line before FOLFIRI wa. 3.9 mo (95% CI: 3.4-5.3 mo). a.t.t.l of 480 cycles wa. complet.d (media.: 6 cycles, ra.ge: 1-51 cycles). t.e ma.n rea.on for discont.nuing FOLFIRI wa. t.mor progression (90.3%). t.mor cont.ol wa. a.hieved in 25 pa.0}ent. (39.7%) (pa.t.a. response: n = 5, st.ble disea.e: n = 20) wit. FOLFIRI. Media. t.P wa. 3.0 mo (95% CI: 2.1-3.9 mo) a.d media. OS wa. 6.6 mo (95% CI: 5.3-8.1 mo). Dose a.a.t.t.on wa. required in 36 pa.0}ent. (57.1%). Fift.en pa.0}ent. (23.8%) ha. gra.e 3-4 t.xicit.es, ma.nly hema.0}logica. (n = 11) or digest.ve (n = 4). Febrile neut.openia.occurred in 3 pa.0}ent.. t.ere wa. no t.xic dea.0}. PS 2 wa. significa.t.y a.socia.0}d w

关键词：转移性胰腺癌铂盐治疗 5-FU 亚叶酸钙中性粒细胞 t.P