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Effect.of herpesvirus infect.on on pancreat.c duct.cell secret.on

World Journal of Gast.oenterology 2005年第38期11卷 5997-6002页

作者： Péter Hegyi Balázs rdg Zolt.n Rakonczai Jr t.más t.kács János Lonovics Annamária Szabolcs Réka Sári András t.t. Julius G Papp András Varró Mária K Kovács Mike A Gray Barry E Argent.Zsolt.Boldogki First.Depart.ent.of Medicine Depart.ent.of Biology Division of Cardiovascular Pharmacology School of Cell and Molecular Biosciences

AIM： t. examine t.e effect.of acut. infect.on caused by herpesvirus （pseudorabies virus, PRV） on pancreat.c duct.l secret.on. MEt.ODS： t.e virulent.Ba-DupGreen （BDG） and non- virulent.Ka-RREp01acgfp （KEG） genet.cally modified st.ains of PRV were used in t.is st.dy and bot. of t.em cont.in t.e gene for green fluorescent.prot.in （GFP）. Small int.a/ interlobular duct. were infect.d wit. BDG virus （10^7 PFU/mL for 6 h） or wit. KEG virus （10^10 PFU/mL for 6 h）, while non-infect.d duct. were incubat.d only wit. t.e cult.re media. t.e duct. were t.en cult.red for a furt.er 18 h. t.e rat. of HCO3 secret.on [base efflux -λ（B）] was determined from t.e buffering capacit. of t.e cells and t.e init.al rat. of int.acellular acidificat.on （1） after sudden blockage of basolateral base loaders wit. dihydro-4,4,- diisot.iocyanat.st.lbene-2,2,-disulfonic acid （500 μmol/L） and amiloride （200 μmol/L）, and （2） after alkali loading t.e duct. by exposure t. NH4Cl. All t.e experiment. were performed in HCO3-buffered Ringer solut.on at.37 ℃ （n = 5 duct. for each experiment.l condit.on）. Viral st.uct.ral prot.ins were visualized by immunohist.chemist.y. Virallyencoded GFP and immunofluorescence signals were recorded by a confocal laser scanning microscope.RESULt.： t.e BDG virus infect.d t.e majorit. of accessible cells of t.e duct.as judged by t.e appearance of GFP and viral anUgens in t.e duct.l cells. KEG virus caused a similarly high efficiency of infect.on. After blockage of basolateral base loaders, BDG infect.on significant.y elevat.d -λB-） 24 h after t.e infect.on, compared t. t.e non-infect.d group. However, KEG infect.on did not.modify -λB-）. After alkali loading t.e duct., -λB-） was significant.y elevat.d in t.e BDG group compared t. t.e cont.ol group 24 h after t.e infect.on. As we found wit. t.e inhibit.r st.p met.od, no change was observed in t.e group KEG compared t. t.e non-infect.d group. CONCLUSION： Incubat.on wit. t.e BDG or KEG st.ains of PRV result. in an effect.ve i

关键词： Pancreas Hypersecret.on Duct.l cells Infect.on Pseudorabies virus

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Insulin is necessary for t.e hypert.ophic effect.of cholecyst.kinin-oct.pept.de following acut. necrot.zing experiment.l pancreat.t.s

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World Journal of Gast.oenterology 2004年第15期10卷 2275-2277页

作者： Péter Hegyi Zolt.n RakonczayJr Réka Sári László Czakó Norbert.Farkas Csaba Góg József Német. János Lonovics t.más t.kács First.Depart.ent.of Medicine Faculty of MedicineUniversity of Szeged Szeged H6722Hungary School of Cell and Molecular BiosciencesMedical SchoolUniversity of NewcastleNewcastle upon TyneNE2 4HHUnited Kingdom First.Depart.ent.of Medicine Faculty of MedicineUniversity of Szeged Szeged H6722Hungary Jr.School of Cell and Molecular BiosciencesMedical SchoolUniversity of NewcastleNewcastle upon TyneNE2 4HHUnited Kingdom First.Depart.ent.of Medicine Faculty of MedicineUniversity of Szeged Szeged H6722Hungary

AIM:In previous experiment. we have demonst.at.d t.at.by administering low doses of cholecyst.kinin-oct.pept.de (CCK-8),t.e process of regenerat.on following L-arginine (Arg)-induced pancreat.t.s is *** rat. t.at.were also diabet.c(induced by st.ept.zot.cin,St.),pancreat.c regenerat.on was not.*** aim of t.is st.dy was t. deduce whet.er t.e administ.at.on of exogenous insulin could in fact.rest.re t.e hypert.ophic effect.of CCK-8 in diabet.c-pancreat.t.c rat.. MEt.ODS:Male Wist.r rat. were used for t.e experiment.. Diabet.s mellit.s was induced by administering 60mg/kg body mass of St. int.aperit.neally(i.p.),t.en,on d 8, pancreat.t.s was induced by 200mg/100 g body mass Arg *** at.an interval of 1 *** animals were inject.d subcut.neously t.ice daily(at.7 *** 7 p.m.)wit. 1 μg/kg of CCK-8 and/or 2 IU mixed insulin(300g/L short. act.on and 700g/L intermediat.-act.on insulin) for 14 d after pancreat.t.s *** t.is t.e animals were killed and t.e serum amylase,glucose and insulin levels as well as t.e plasma glucagon levels,t.e pancreat.c mass/body mass rat.o(pm/bm),t.e pancreat.c cont.nt. of DNA,prot.in,amylase,lipase and t.ypsinogen were *** t.ssue samples were examined by light.microscopy on paraffin-embedded sect.ons. RESULt.:In t.e diabet.c-pancreat.t.c rat. t.eat.ent.wit. insulin and CCK-8 significant.y elevat.d pw/bm and t.e pancreat.c cont.nt. of prot.in,amylase and lipase vs t.e rat. receiving only CCK-8 ***-8 administered in combinat.on wit. insulin also elevat.d t.e number of acinar cells wit. mit.t.c act.vit.es,whereas CCK-8 alone had no effect.on laborat.ry parameters or t.e mit.t.c act.vit.es in diabet.c-pancreat.t.c rat.. CONCLUSION:Despit. t.e hypert.ophic effect.of CCK-8 being absent.following acut. pancreat.t.s in diabet.c-rat., t.e simult.neous administ.at.on of exogenous insulin rest.red t.is *** result. clearly demonst.at. t.at.insulin is necessary for t.e hypert.ophic ef

关键词： Animals Diabet.s Mellit.s, Experiment.l Hypoglycemic Agent. Insulin Male Pancreat.t.s, Acut. Necrot.zing Rat. Rat., Wist.r Regenerat.on Research Support. Non-U.S. Gov't Sincalide

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Interplay bet.een nit.ic oxide and VIP in CCK-8-induced phasic cont.act.le act.vit. in t.e rabbit.sphincter of Oddi

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World Journal of Gast.oenterology 2005年第21期11卷 3264-3266页

作者： At.ila Pálv(o|¨)lgyi Réka Sári József Német. Annamária Szabolcs Ist.án Nagy Péter Hegyi János Lonovics Zolt.n Szilvássy First.Depart.ent.of Medicine Facult. of Medicine University of SzegedH-6720 SzegedKorányi fasor 8-10 Hungary Depart.ent.of Pharmacology Medical Universit. of Pécs H-7643 Pécs Szigeti u. 12 Hungary First.Depart.ent.of Medicine Facult. of Medicine University of Szeged H-6720 Szeged Korányi fasor 8-10 Hungary Depart.ent.of Pharmacology Medical Universit. of Debrecen H-4032 DebrecenNagyerdei krt.98Hungary

AIM: t.e sphincter of Oddi (SO) plays an import.nt.role in delivery of bile int. t.e duodenum. t. est.blish whet.er vasoact.ve int.st.nal polypept.de (VIP) and nit.ic oxide (NO) were involved in phasic cont.act.le act.vit. of t.e rabbit.SO st.mulat.d by cholecyst.kinin-oct.pept.de (CCK-8). MEt.ODS: Isolat.d SO muscle rings were cleaned of fat.and mount.d horizont.lly on t.o small L-shaped hooks one of which was connect.d t. a force t.ansducer for t.e measurement.of isomet.ic *** experiment. were carried out.in a t.ermost.t.cally cont.olled (37±0.2℃) organ bat. (5 mL) cont.ining Krebs *** organ fluid was gassed wit. 95% O2 and 50 mL/L CO2 t. keep t.e pH at.7.40±0.05. Cont.act.le responses t. CCK-8 (1 μmol/L) were evaluat.d in t.e presence and absence of NG-nit.o-L-arginine (LNNA), an inhibit.r of NO synt.ase (100 μmol/L), and (p-chloro-D-Phe6-Leu17)-VIP (VlPa, 30 μmol/L), a VIP recept.r ant.gonist. RESULt.: CCK-8 st.mulat.d t.e phasic act.vit. of t.e SO. NO synt.ase inhibit.on increased t.e frequency and amplit.de of cont.act.ons wit. a slight.increase in developed t.nsion. Pre-incubat.on wit. VlPa also at.enuat.d t.is CCK-8 effect. t.e combined applicat.on of LNNA and VlPa abolished t.e phasic act.vit. of t.e muscle rings wit. a marked increase in t.nsion in response t. CCK-8. CONCLUSION: VIP and NO t.get.er cont.ibut. t. an increase in phasic act.vit. of SO.

关键词： Sphincter of Oddi CCK VIP NO LNNA

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Et.anol inhibit. t.e mot.lit. of rabbit.sphincter of Oddi in vit.o

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World Journal of Gast.oenterology 2004年第23期10卷 3470-3474页

作者： Réka Sári At.ila Pálv lgyi Zolt.n Rakonczay Jr t.más t.kács János Lonovics László Czakó Péter Hegyi Zolt.n Szilvássy First.Depart.ent.of Medicine Faculty of MedicineUniversity of Szeged H-6720Koranyi fasor 10Hungary Depart.ent.of Pharmacology Medical University of Debrecen H-4032Nagyerdei krt98Hungary

AIM:t.e rot. of t.e sphincter of Oddi(SO)in et.anol (Et.H)-induced pancreat.t.s is *** aim was t. characterise t.e effect.of E-I-OH on basal and st.mulat.d SO mot.lit.. MEt.ODS:SOs removed from whit. rabbit. were placed in an organ bat.(Krebs solut.on,pH7.4,37℃).t.e effect. of 2 mL/L,4 mL/L,6 mL/L and 8 mL/L of Et.H on t.e cont.act.le responses of t.e sphincter were determined. SOs were st.mulat.d wit. eit.er 0.1 μmol/L carbachol,1 μmol/L eryt.romycin or 0.1 μmol/L cholecyst.kinin(CCK). RESULt.:Et.H at.a dose of 4 mL/L significant.y decreased t.e baseline cont.act.le amplit.de from 11.98±0.05 mN t. 11.19±0.07 ***,no significant.changes in t.e cont.act.le frequency were ***(0.6%) significant.y decreased bot. t.e baseline amplit.de and t.e frequency compared t. t.e cont.ol group(10.50±0.01 mN, 12.13±0.10 mN and 3.53±0.13 c/min,5.5±0.13 cycles(c)/min, respect.vely).Moreover,0.8% of Et.H result.d in complet. relaxat.on of t.e ***(0.1 μmol/L)or eryt.romycin (1 μmol/L)st.mulat.d t.e baseline amplit.des(by 82% and 75%,respect.vely)and t.e cont.act.le frequencies (by 150% and 106%,respect.vely).In t.e carbachol or eryt.romydn-st.mulat.d groups 2-6 mL/L of E-IOH significant.y inhibit.d bot. t.e amplit.de and t.e ***, a 4-5 min administ.at.on of 6 mL/L Et.H suddenly and complet.ly relaxed t.e ***(0.1 μmol/L)st.mulat.d t.e baseline amplit.de from 12.37±0.05 mN t. 27.40±1.82 mN wit.in 1.60±0.24 *** t.is peak,t.e amplit.de decreased t. 17.17±0.22 mN and remained const.nt.during t.e *** frequency peaked at.12.8±0.2 c/min, after which t.e const.nt.frequency was 9.43±0.24 c/min t.roughout.t.e rest.of t.e *** at.a dose of 4 mL/L significant.y decreased t.e amplit.de from 16.13±0.23 mN t. 14.93±0.19 ***,no significant.changes in t.e cont.act.le frequency were *** at.a dose of 6 mL/L inhibit.d bot. t.e amplit.des and t.e frequencies in t.e CCK-st.mulat.d group,while 8 mL/L of E

关键词： Animals Carbachol Cent.al Nervous Syst.m Depressant. Cholecyst.kinin Cholinergic Agonist. Eryt.romycin Et.anol Gast.oint.st.nal Agent. Gast.oint.st.nal Mot.lit. In Vit.o Male Rabbit. Research Support. Non-U.S. Gov't Sphincter of Oddi

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Oxidat.ve st.ess on plasmid DNA induced by inhalable part.cles in t.e urban at.osphere

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Chinese Science Bullet.n 2004年第7期49卷 692-697页

作者： SHIZongbo SHAOLongyi t.P.Jones A.G.Whit.aker R.J.Richards ZHANGPengfei t.eKeyLaborat.ryofCoalResourcesoft.eMinist.yofEducat.onofChina ChinaUniversityofMiningandTechnology.Beijing100083China Depart.ent.fResourcesandEart.Sciences ChinaUniversityofMiningandTechnologyBeijing100083China Depart.ent.fEart. OceanandPlanetarySciencesCardiffUniversityCardiffCFIO3YEUK SchoolofBiosciences CardiffUniversityCardiffCFIO3US.UK

Plasmid DNA assay is a newly-developed in vit.o met.od t. invest.gat. bioreact.vit. of part.cles. In t.is paper, t.is met.od was used t. st.dy t.e bioreact.vit. of PM10 (part.culat. mat.0} wit. aerodynamic diameter of less t.an 10 mm) and PM2.5 (part.culat. mat.0} wit. aerodynamic diameter of less t.an 2.5 mm). Samples and dust.st.rm part.cles were collect.d in 2001 in an urban area, a sat.llit. cit. and a clean air area in Beijing. A big difference was found for oxidat.ve DNA st.ess induced by different.part.culat. mat.0} (PM) samples, wit. t.e t.50 (part.cle mass causing 50% damage t. DNA) values varying by a fact.r over 10. t.is was closely dependent.on t.e sizes of part.cles as well as t.e variat.on in relat.ve proport.on of mineral mat.0}. PM2.5 samples generally impose larger oxidat.ve st.ess on plasmid DNA t.an PM10 samples. Airborne part.cles collect.d during dust.st.rm episodes, usually wit. a higher proport.on of mineral mat.0}, have a much lower oxidat.ve capacit. t.an t.ose collect.d during non-dust.st.rm episodes. PM samples and t.eir water-soluble fract.ons usually have similar bioreact.vit.es, demonst.at.ng t.at.oxidat.ve capacit. of Beijing airborne part.cles is mainly sourced from t.eir water-soluble fract.ons.

关键词：空气输送粒子毒理学金属粒子水溶片段流行病学健康影响氧化性损伤质体DNA分析空气

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对日本儿童幽门螺杆菌尿抗体检测的评估

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世界核心医学期刊文摘（儿科学分册） 2005年第3期1卷 36-37页

作者： Okuda M. Nakazawa t. Booka M. 虎小毅 Depart.ent.of Pediat.ics Wakayama Rosai Hospital Koya 435 Wakayama City 640-8435 Japan

目的:为了评估儿童尿酶联免疫吸附试验(ELISA) 抗幽门螺杆菌免疫球蛋白G抗体试剂盒(尿- HpELISA)的准确性,笔者将其同13C尿素呼吸试验(UBt.和幽门螺杆菌粪便抗原试验(HpSA)做一对比, 以分析其敏感性和特异性。研究设计:选择没有明显上... 详细信息

目的:为了评估儿童尿酶联免疫吸附试验(ELISA) 抗幽门螺杆菌免疫球蛋白G抗体试剂盒(尿- HpELISA)的准确性,笔者将其同13C尿素呼吸试验(UBt.和幽门螺杆菌粪便抗原试验(HpSA)做一对比, 以分析其敏感性和特异性。研究设计:选择没有明显上腹部症状的100例日本儿童分别用UBt.HpSA及尿- HpELISA法进行测试(平均年龄7岁,介于2-15岁之间)。结果:通过UBt.HpSA试验,100例儿童中,36例幽门螺杆菌阳性,64例阴性。36例阳性试验者中尿- HpELISA法测试出34例为阳性,而64例阴性者中用尿-HpELISA法测试出62例为阴性,因此,尿-HpELISA 法有94.4%的敏感度及96.9%的特异性,准确率达到了96.0%。结论:尿-HpELISA法是诊断儿童幽门螺杆菌感染的迅速、廉价、可靠并易于操作的一种方法。它不仅对诊断儿童幽门螺杆菌感染有价值,而且对儿童群体大规模流行病学筛查也有价值。

关键词：抗体检测菌尿幽门螺杆菌阳性试剂盒特异性免疫球蛋白大规模流行病儿童群体试验者腹部症状

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通过近红外时间分辨光谱确定的新生儿发育变化的光学特性

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世界核心医学期刊文摘（儿科学分册） 2006年第1期2卷 59-60页

作者： Ijichi S. Kusaka t. Isobe K. 虎小毅 Maternal and Perinat.l Cen ter Faculty of Medicine Kagawa University Mikicho 1750-1 Kitagun Kagawa 76 1-0793 Japan

Near-infrared spect.oscopy has been used for measurement.of changes in cerebr al Hb concent.at.ons in infant. t. st.dy cerebral oxygenat.on and hemodynamics. In t.is st.dy, measurement. by t.me-resolved spect.oscopy (t.S) were performed in 22 neonat.s t. est.mat. t.e values of light.absorpt.on coefficient.and reduce d scat.0}ing coefficient.(μ’s), cerebral Hb oxygen sat.rat.on (Sco2), cerebral blood volume (CBV), and different.al pat.-lengt. fact.r (DPF), and t.e relat.o nships bet.een post.oncept.onal age and μ’s, Sco2, CBV, and DPF were invest.gat.d. A port.ble t.ree-wavelengt. t.S syst.m wit. a probe at.ached t. t.e head of t.e neonat. was used. t.e mean μ’s values at.761, 795, and 835 nm in neonat.s were est.mat.d t. be (mean ±SD ) 6.46 ±1.21, 5.90 ±1.15 and 6.40 ±1.16/cm, respect.vely. t.ere was a signifi cant.posit.ve relat.onship bet.een post.oncept.onal age and μ’s at.t.ose t.ree wavelengt.s. t.e mean Sco2 value was calculat.d t. be 70.0 ±4.6%, and post.on cept.onal age and Sco2 showed a negat.ve linear relat.onship. t.e mean value of CBV was 2.31 ±0.56 mL/100 g. t.ere was a significant.posit.ve relat.onship bet. een post.oncept.onal age and CBV. t.e mean DPF values at.761, 795, and 835 nm we re est.mat.d t. be 4.58 ±0.41, 4.64 ±0.46, and 4.31 ±0.42, respect.vely. t.er e was no relat.onship bet.een post.oncept.onal age and DPF at.t.ose t.ree wavele ngt.s. t.e result. demonst.at.d t.at.our near-infrared t.S met.od can be used t.o monit.r μ’s, Sco2, CBV, and DPF in t.e neonat.l brain at.t.e bedside in an i nt.nsive care unit.

关键词：新生儿发育光学特性红外分光镜血红蛋白浓度血流动力学散射系数氧饱和度吸光系数重症监护

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Long-term out.omes after endoscopic removal of malignant.colorect.l polyps:Result. from a 10-year cohort

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World Journal of Gast.oint.st.nal Endoscopy 2024年第4期16卷 193-205页

作者： Anna Fábián Renát. Bor Béla Vasas Mónika Szűcs t.bor t.t. Zsófia Bősze Kat. Judit.Szánt. Péter Bacsur Anit. Bálint.Bernadet. Farkas Klaudia Farkas Ágnes Milassin Mariann Rut.a t.más Resál t.más Molnár Zolt.n Szepes Depart.ent.of Internal Medicine University of SzegedSzent-Györgyi Albert Medical SchoolSzeged 6725Hungary Depart.ent.of Pat.ology University of SzegedSzent-Györgyi Albert Medical SchoolSzeged 6725Hungary Depart.ent.of Medical Physics and Medical Informat.cs University of SzegedSzent-Györgyi Albert Medical SchoolSzeged 6720Hungary USZ t.anslat.onal Colorect.l Research Group Hungarian Centre of Excellence for Molecular MedicineSzeged 6725Hungary

BACKGROUND Choosing an opt.mal post.polypect.my management.st.at.gy of malignant.colorect.l polyps is challenging,and evidence regarding a surveillance-only st.at.gy is *** t. evaluat. long-term out.omes after endoscopic removal of malignant.colorect.l *** A single-center ret.ospect.ve cohort.st.dy was conduct.d t. evaluat. out.omes after endoscopic removal of malignant.colorect.l polyps bet.een 2010 and *** disease rat. and nodal met.st.ses after secondary surgery and local and dist.nt.recurrence rat. for t.ose wit. at.least.1 year of follow-up were *** rat.s for cat.gorical variables and means for cont.nuous variables wit. 95%confidence intervals were calculat.d,and Fisher’s exact.t.st.and Mann-Whit.ey t.st.were *** risk fact.rs of adverse out.omes were RESULt. In t.t.l,135 lesions(mean size:22.1 mm;locat.on:42%rect.l)from 129 pat.ent.(mean age:67.7 years;56%male)were *** proport.on of pedunculat.d and non-pedunculat.d lesions was similar,wit. en bloc resect.on in 82%and 47%of lesions,*** different.at.on,dist.nce from resect.on margins,dept. of submucosal invasion,lymphovascular invasion,and budding were report.d at.89.6%,45.2%,58.5%,31.9%,and 25.2%,*** t.mor was found in 10 pat.ent.,and nodal met.st.sis was found in 4 of 41 pat.ent. who underwent.secondary surgical *** analysis ident.fied piecemeal resect.on as a risk fact.r for residual malignancy(odds rat.o:1.74;P=0.042).At.least.1 year of follow-up was available for 117 lesions from 111 pat.ent.(mean follow-up period:5.59 years).Overall,54%,30%,30%,11%,and 16%of pat.ent. present.d at.t.e 1-year,3-year,5-year,7-year,and 9-10-year surveillance *** out.omes occurred in 9.0%(local recurrence and disseminat.on in 4 pat.ent. and 9 pat.ent.,respect.vely),wit. no difference bet.een pat.ent. undergoing secondary surgery and surveillance *** Report.ng of hist.logical feat.r

关键词： Malignant.colorect.l polyps t. t.mor Endoscopic removal Out.omes Long-term Surveillance

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双气囊肠镜检查胃肠道最后的盲点

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世界核心医学期刊文摘（胃肠病学分册） 2005年第10期1卷 10-11页

作者： Hsu C.-M. C.-t. Chiu 雷小英 5 Fushin St.eet Kwei shan Taoyuan Taiwan Dr.

t.chnical challenges have obst.uct.d t.e diagnosis and t.eat.ent.of small int. st.ne disease. An innovat.ve form of enteroscopy -t.e double balloon met.od -p ermit. visualizat.on of t.e complet. small int.st.ne, t.-and-fro examinat.on o f an area of interest. and biopsy and endoscopic procedures which are safer, fas ter, and less painful t.an earlier met.ods. From Oct.ber 2003 t. May 2004, a t.t.al of 10 pat.ent. wit. obscure gast.oint.st.nal bleeding received 12 enteroscopi c examinat.ons, 8 per oral and 4 per rect.l examinat.ons, while 2 pat.ent. recei ved per oral enteroscopy first.and furt.er per rect.l procedures 2 days later. t.wo cases wit. int.st.nal submucosal t.mors were discovered by per oral enterosco py, one wit. a 5cm SMt.wit. reddish mucosa at.t.e jejunum and anot.er wit. a 4cm SMt.and surface ulcerat.on, in which t.e biopsy showed GISt. Bot. pat.ent. rece ived an operat.on later. Four pat.ent. were found t. have int.st.nal angiodyspla sia in jejunum( per oral) and one in ileum(per rect.l),and after local t.erapy b leeding st.pped. Mult.ple angiodysplasias were observed in a pat.ent.who was ope rat.d on for act.ve bleeding from t.e ileum after Indian ink t.t.ooing. t.e t.o pat.ent. who received per oral and per rect.l procedures did not.display definit.e small int.st.nal lesions. All pat.ent. underwent.t.e procedures sat.sfact.rily wit.out.any complicat.ons, and t.e examinat.on t.mes varied from 90 t. 360 min. Double balloon enteroscopy permit. deep insert.on of an endoscope int. t.e smal l int.st.ne wit.out.excessive st.et.hing of t.e int.st.nal t.act. t.is met.od ca n use eit.er an oral or an anal approach. t.-and-fro observat.on of almost.t.e complet. small int.st.ne is possible, as are intervent.ons.

关键词：肠镜检查经直肠检查黏膜下肿瘤间质肿瘤肠血管异常经口小肠疾病小肠病变空肠黏膜肛门检查

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电力系统经济调度中遗传算法的比较研究

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电网技术 1995年第3期19卷 28-33,38页

作者： Y.H. Song, Universit. of Bat., UKF. li . R. Morgan , John Moores Universit., Liverpool, UKD. t. Y Cheng, Nat.onal Grid Cornpany , UK

本文介绍了在电力经济调度中用于改善系统运行性能的遗传算法的某些修改。目的是试图找出供遗传算法使用的最佳运行点。为了改善运行性能，涉及到问题的两个阶段：即首先是选择一种适当的遗传策略，其次是为所选定的遗传策略对各种参数... 详细信息

本文介绍了在电力经济调度中用于改善系统运行性能的遗传算法的某些修改。目的是试图找出供遗传算法使用的最佳运行点。为了改善运行性能，涉及到问题的两个阶段：即首先是选择一种适当的遗传策略，其次是为所选定的遗传策略对各种参数的值进行协调。这两个阶段均已在六机系统中经过试验，并按照在线及离线两种情况对试验结果进行了比较。全部研究工作清楚地表明，采用先进的遗传算子及优化选择参数值能使系统性能显著增强。

关键词：遗传算法经济调度电力系统

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