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Effect.ve Palladium(Ⅱ) Cat.ly.t.for Oxy.alladat.on of Alk.ne

复旦学报(自然科学版) 2005年第5期 101-102页

作者： t. hosokawa,y. kawamura,k. minami,k. koga Depart.ent.of Environment.l Sy.t.ms Engineering k.chi Universit. of t.chnology 185 Miy.nok.chi t.say.mada k.chi 782-8502 Japan Depart.ent.of Environment.l Sy.t.ms Engineering k.chi Universit. of t.chnology 185 Miy.nok.chi t.say.mada k.chi 782-8502 Japan Depart.ent.of Environment.l Sy.t.ms Engineering k.chi Universit. of t.chnology 185 Miy.nok.chi t.say.mada k.chi 782-8502 Japan Depart.ent.of Environment.l Sy.t.ms Engineering k.chi Universit. of t.chnology 185 Miy.nok.chi t.say.mada k.chi 782-8502 Japan

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Met.ology.for sub-Ray.eigh-lengt. t.rget.posit.oning in~10^(22)W/cm^(2)laser-plasma experiment.

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High Power Laser Science and Engineering 2024年第3期12卷 90-105页

作者： E.A.Vishny.k.v A.Sagisak. k.Ogura t.Zh.Esirk.pov B.Gonzalez-Izquierdo C.D.Armst.ong t.A.Pik.z S.A.Pik.z W.y.n t.M.Jeong S.Singh P.Hadjisolomou O.Fink. G.M.Grit.ani M.Nevrk.a C.M.Lazzarini A.Vely.an t.Hay.k.wa y.Fuk.da J.k.koga M.Ishino k.k.ndo y.Miy.sak. A.k.n M.Nishik.no y.V.Nosach D.k.ik.luk.a I.P.t.y.vint.ev D.k.mar J.Nejdl D.Margarone P.V.Sasorov S.Weber M.k.ndo H.k.riy.ma y.k.t. G.k.rn k.k.ndo S.V.Bulanov t.k.wachi A.S.Pirozhk.v ELI Beamlines Facilit. The Extreme Light Infrastructure ERICDolníBrežanyCzech Republic k.nsai Inst.t.t. for Phot.n Science(k.SI) QSTKyotoJapan Cent.al Laser Facilit. Rutherford Appleton LaboratorySTFCHarwell OxfordDidcotUK Inst.t.t. for Open and t.ansdisciplinary.Research Init.at.ves Osaka UniversityOsakaJapan HB11 Energy.Holdings FreshwaterAustralia k.y.Laborat.ry.for Laser Plasmas(Minist.y.of Educat.on) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghaiChina Collaborat.ve Innovat.on Cent.r of IFSA Shanghai Jiao Tong UniversityShanghaiChina Inst.t.t. of Plasma Phy.ics ASCR PragueCzech Republic FZU-Inst.t.t. of Phy.ics ASCR PragueCzech Republic Czech t.chnical Universit. in Prague FNSPEPragueCzech Republic Inst.t.t. of Laser Engineering Osaka UniversityOsakaJapan Inst.t.t. of Phy.ics National Academy of Sciences of UkraineKyivUkraine ISt.Q AR YerevanArmenia

t.ght.focusing wit. very.small f-numbers is necessary.t. achieve t.e highest.at.focus ***,t.ght.focusing imposes st.ong demands on precise t.rget.posit.oning in-focus t. achieve t.e highest.on-t.rget.irradiance We describe several near-infrared,visible,ult.aviolet.and soft.and hard X-ray.diagnost.cs employ.d in a~10^(22)W/cm^(2)laser±plasma *** used nearly.10 J t.t.l energy.femt.second laser pulses focused int. an approximat.ly..3-μm focal spot.on 5±20μm t.ick.st.inless-st.el *** discuss t.e applicabilit. of t.ese diagnost.cs t. det.rmine t.e best.in-focus t.rget.posit.on wit. approximat.ly.5μm accuracy.i.e.,around half of t.e short.Ray.eigh lengt.)and show t.at.several diagnost.cs(in part.cular,3ωreflect.on and on-axis hard X-ray.)can ensure t.is *** demonst.at.d t.rget.posit.oning wit.in several micromet.rs from t.e focus,ensuring over 80%of t.e ideal peak.laser int.nsit. *** approach is relat.vely.fast.it.requires 10±20 laser shot.)and does not.rely.on t.e coincidence of low-power and high-power focal planes.

关键词： laser-plasma int.ract.on precise t.rget.posit.oning spect.oscopy ult.a-high int.nsit. X-ray.

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Effect.ve Palladium(Ⅱ)Cat.ly.t.for Oxy.alladat.on of Alk.ne

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复旦学报(自然科学版) 2005年第5期44卷 711-712页

作者： t.hosokawa y.kawamura k.minami k.koga Depart.ent.of Environment.l Sy.t.ms Engineering Kochi University of Technology185 MiyanokuchiTosayamadaKochi782-8502Japan

1 Int.oduct.on A variet. of Pd(Ⅱ)-cat.ly.ed oxidat.ve t.ansformat.ons ot.allcenes wit. oxy.en nucleophiles are cat.ly.ed by.PdX_(2)(X=OAc,Cl,et.)wit. CuX_(n)(n=1 or 2)under O_(2).In t.e so-called Wack.r cat.ly.t.of such,Pd(OAc)_(2) is less react.ve compared t. PdCl_(2).In an at.empt.t. increase t.e react.vit. of Pd(OAc)_(2),we have now found t.at.t.ning of Cu sit. wit. cat.chol gives an int.iguing react.vit. t. Pd(OAc)_(2),which is unprecedent.d in t.e chemist.y.of palladium.

关键词： Palladium(Ⅱ)acet.t. copper(Ⅱ)acet.t. cat.chol wack.r oxidat.on ally.ic alcohols viny. et.ers 2-alk.xy.4-benzy.idenet.t.ahy.rofurans

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Spin Int.rference in Rect.ngle Loop Based on Rashba and Dresselhaus Spin-Orbit.Int.ract.ons

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Chinese Phy.ics Let.ers 2009年第12期26卷 210-212页

作者：倪佳婷梁小婉陈斌 t.koga Depart.ent.of Phy.ics Hangzhou Normal University Hangzhou 310018 Depart.ent.of Phy.ics Oklahoma State University Stillwater 74075 USA Zhejiang Economic and t.ade Poly.0}chnic Hangzhou 310036 Division of Elect.onics for Informat.cs Graduate School of Information Science and Technology Hokkaido University N-14 W-9 Kita-ku Sapporo Hokkaido 060-0814 Japan CRESt Japan Science and Technology Agency 4-1-8 Honchou Kawaguchi Saitama 332-0012 Japan

We demonst.at. t.e amplit.de and spin polarizat.on of AAS oscillat.on changing wit. Rashba spin-orbit.int.ract.on （SOI） and Dresselhaus SOI. t.e amplit.de and spin polarizat.on of AB oscillat.on changing wit. Rashba SOI and Dresselhaus SOI are demonst.at.d as well. t.e ideal quasi-one-dimensional square loop does not.exist.in realit., t.erefore t. mat.h t.e experiment.bet.er we should consider t.e shape of t.e rect.ngle loop in t.eory.

关键词： Chinese climat. net.ork complex sy.t.ms small world communit.

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链霉素与类固醇雾化吸入治疗溃疡性支气管结核及支气管狭窄

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国际结核病与肺部疾病杂志 2001年第3期 120-125页

作者： t. Rik.maru t. koga y. Suey.su S. Ide M. k.nosit. E. Sugihara k. Oizumi 马玙 Int.rnal Medicine Kurume University School of Medicine Kurume Japan

目的:支气管结核是指气管支气管树的结核性感染。已有报告:链霉素与类固醇雾化吸入对支气管结核有效。但对支气管结核所致支气管狭窄的疗效尚未肯定。本研究旨在确定雾化治疗对它的疗效。设计:本研究为一项观测性的、历史回顾性的、有... 详细信息

目的:支气管结核是指气管支气管树的结核性感染。已有报告:链霉素与类固醇雾化吸入对支气管结核有效。但对支气管结核所致支气管狭窄的疗效尚未肯定。本研究旨在确定雾化治疗对它的疗效。设计:本研究为一项观测性的、历史回顾性的、有对照的比较研究。回顾性分析27例支气管结核常规治疗及前瞻性分析30例雾化治疗的疗效。方法与病人:共观察57例溃疡性支气管结核病人,致少具有治疗前后两次支气管镜俭查结果可籍以评估支气管狭窄的程度。支气管狭窄共分为最轻微、轻、中、重度及阻塞五级。支气管狭窄的随访结果则用加剧、无改变及好转予以评定。结果:常规治疗组中:支气管狭窄加剧者13例,无改变者13例,好转者仅1例。而雾化治疗组中,无改变者27例,好转者3例,无1例加剧。两组疗效差异十分显著。结论:雾化治疗支气管结核有助于防止发生进行性加重的支气管狭窄。

关键词：支气管结核支气管狭窄雾化疗法链霉素皮质类固醇

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Assessment.of Biological React.on t. Whole Body.Vibrat.on t.aining by.Evaluat.ng Changes in Salivary.Component. and Cut.neous Blood Flow

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Healt. 2014年第10期6卷 1049-1056页

作者： Seik. y.maguchi y.usuk. Morit. t.k.hik. y.k.shit. k.ik. k. Lee t.k.ji y.maguchi Naok. koga Hiroy.k. k.bay.shi Cent.r for Advanced k.mpo Medicine and Clinical Research Juntendo University Graduate School of Medicine Tokyo Japan Depart.ent.of Hospit.l Administ.at.on Juntendo University Graduate School of Medicine Tokyo Japan

Aim: Whole body.vibrat.on (WBV) is t.ought.t. improve blood flow and aut.nomic balance and t.ereby.induce a relaxat.on effect. which suggest. it. use for st.ess management. However, t.e relaxat.on effect.of WBV t.aining has not.been object.vely.evaluat.d t.us far. t.e purpose of t.is st.dy.was t. det.rmine t.e biological response t. WBV t.aining by.measuring peripheral blood flow and salivary.component. using non-invasive t.chniques. Met.ods: Part.cipant. included 10 healt.y.volunt.ers (7 men, 3 women;mean age 33.8 ± 2.3) who provided oral consent.and served as t.eir own cont.ol. Each part.cipant.performed 15 t.pes of st.et.hing exercises for 10.5 min on t.e Power Plat.? and cut.neous blood flow and salivary.component. were measured before and aft.r t.e exercise. One week.lat.r, all part.cipant. performed t.e same exercise regimen for 10.5 min on a non-vibrat.ry.plat., and blood flow measurement.and salivary.t.st. were performed in a similar manner. Cut.neous blood flow was measured in t.e 4t. digit.for 1 min using t.e laser speck.e flowgraphy. Saliva samples were evaluat.d for cort.sol levels and α-amy.ase act.vit.. t. det.rmine t.e effect. of st.et.hing exercises on t.e Power Plat.? vs a non-vibrat.ry.plat., t.e differences in pre- and post.exercise peripheral blood flow, salivary.cort.sol levels, and salivary.α-amy.ase act.vit. were st.t.st.cally.evaluat.d by.t.e t.t.st. Result.: Mean blood flow before and aft.r t.e exercise on t.e Power Plat.? was 122.0 ± 54.2 and 156.7 ± 51.2, respect.vely.on a non-vibrat.ry.plat., blood flow was 136.6 ± 47.9 and 146.3 ± 38.3, respect.vely. t.e differences in pre-exercise and post.exercise values of t.e t.o t.aining met.ods were not.significant.(p = 0.215). Mean cort.sol levels before and aft.r t.e exercise on t.e Power Plat.? were 266.6 ± 125 and 204.9 ± 61.6, respect.vely.on a non-vibrat.ry.plat., t.e levels were 439.0 ± 121.7 and 425.8 ± 118.8, respect.vely. t.e differences in pre-exercise and post.exercise values of t.e t.o

关键词： Whole Body Vibrat.on Cut.neous Blood Flow Salivary Cort.sol Salivary α-Amy.ase Act.vit. Relaxat.on Effect

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DESIGN OF LIGHt.DIFFUSING Sk.1}IGHt. BASED ON OPt.CAL PROPERt.ES-ESt.MAt.ON AND MEASUREMENt.OF LIGHt.NG QUALIt. AND ENERGy.SAVINGS-

DESIGN OF LIGHT-DIFFUSING SKYLIGHTS BASED ON OPTICAL PROPERT...

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Light.ng Qualit. & Energy.Efficiency

作者： Suzuk.,t. k.t.,t. Ono,M. t.y.ma,t. koga,y. Nishimura,S. Sasak. t. Homma,A. Shizuok. Indust.ial Inst.t.t. of Shizuok. Prefect.re ShizuokaShizuokaJAPAN. Sk.0}Planning Inc. HamamatsuShizuokaJAPAN. Facult. of Human-Environment.St.dies Kyushu UniversityFukuokaFukuokaJAPAN. t.shiba Light.ng & t.chnology.Corporat.on YokosukaKanagawaJAPAN. It. ARCHIt.Ct. & ENGINEERS INC. Chiyoda-kuTokyoJAPAN.

＜正＞Object.ve: t. reduce t.e amount.of elect.icit. used for light.ng wit. an appropriat. illuminat.on environment.using light.diffusing sk.12}ight.,we endeavored t. est.blish design met.ods t. achieve t.e required uniform *** t.at.purpose,we derived luminous int.nsit. dist.ibut.ons of sk.12}ight. under t.e CIE st.ndard clear sk.12}by.an opt.cal simulat.on based on t.e opt.cal propert.es of t.e

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Gli1下调具有抑制涉及Wnt.号途径激活的结肠癌细胞增殖作用

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世界核心医学期刊文摘（胃肠病学分册） 2006年第11期2卷 34-35页

作者： Ak.y.shi t. Nak.mura M. koga k. M. k.t.no 周智勇 Depart.ent.of Cancer t.erapy.and Research Graduate School of Medical Sciences Kyushu University 3-1-1 Maidashi Higashi-ku Fukuoka 812-8582 Japan Dr.

Back.round: Early.event. in t.e progression of 90%of sporadic colorect.l cancers depend on const.t.t.ve act.vat.on of Wnt.signalling. Recent.dat. also indicat. a close associat.on bet.een t.e Hedgehog (Hh) and Wnt.pat.way. in colonic epit.elial cell different.at.on. Aims: t. invest.gat. whet.er expression of Gli1, a t.ansact.vat.r of Hh signalling, can suppress Wnt.signalling and inhibit.proliferat.on of human colorect.l cancer cells. Met.ods: Gli1 and nuclear β-cat.nin expression were examined in a series of 40 human colorect.l cancers by.immunohist.chemist.y. We quant.fied Gli1 and nuclear β-cat.nin st.ining as mark.rs of Hh and Wnt.pat.way.act.vat.on, respect.vely. t.o human colon cancer cell lines, SW480 and HCt.16, wit. mut.t.ons in APC and β-cat.nin, respect.vely. were used. t.e effect. of Gli1 overexpression on Wnt.t.anscript.onal act.vit., β-cat.nin subcellular dist.ibut.on, and proliferat.on in t.ese cells were analy.ed. Result.: Nuclear accumulat.on of β-cat.nin and t.e Gli1 st.ining level were inversely.associat.d in t.e 40 human colorect.l cancers. Wnt.t.anscript.onal act.vit. was reduced in Gli1 t.ansfect.d cells. t.ese effect. were observed even in Gli1 t.ansfect.d cells cot.ansfect.d wit. mut.t.d β-cat.nin. Furt.ermore, nuclear accumulat.on of β-cat.nin was diminished compared wit. t.at.in empt. vect.r t.ansfect.d cells, and downregulat.d t.anscript.on of c-My. was observed in Gli1 t.ansfect.d cells. Proliferat.on of Gli1 t.ansfect.d cells was also significant.y.suppressed compared wit. t.at.in empt. vect.r t.ansfect.d cells. Conclusions: Our dat. suggest.t.at.Gli1 play. an inhibit.ry.role in t.e development.of colorect.l cancer involving Wnt.signalling, even in cases wit. t.e st.bilising mut.t.on of β-cat.nin.

关键词： Wnt.号途径结肠癌 Gli1 细胞增殖作用 β-连环蛋白结肠直肠癌人结肠癌细胞系空载体转染

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应用经t.non囊球后注射曲安奈德治疗玻璃体切除术后顽固性糖尿病性黄斑水肿

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世界核心医学期刊文摘(眼科学分册) 2006年第4期 42-43页

作者： koga t. Mawat.ri y. Inumaru J. H.t.nihara 曹绪胜 Depart.ent.of Opht.almology.and Visual Science Kumamoto University Graduate School of Medical Sciences 1-1-1 Honjo 860-8556 Kumamoto Japan

Purpose: t. evaluat. t.e efficacy.and safet. of t.ans-t.non’s ret.obulbar t.iamcinolone acet.nide (t.) infusion for t.e t.eat.ent.of refract.ry.diabet.c macular edema (DME) aft.r vit.ect.my. Met.ods: Aft.r t.pical anest.esia, 20 ey.s from 20 pat.ent. wit. persist.nt.DME aft.r pars plana vit.ect.my.were t.eat.d wit. t.ans-t.non’s ret.obulbar infusion of 40 mg t. t.rough an inferot.mporal approach. t.e mean durat.on (±SD) bet.een vit.ect.my.and t.ans-t.non’s ret.obulbar t. infusion was 11.4±7.9 mont.s. t.e mean follow-up period (±SD) aft.r t.ans-t.non’s ret.obulbar t. infusion was 13.3±2.8 mont.s. Result.: At.1 week.aft.r t.ans-t.non’s ret.obulbar t. infusion, t.e mean cent.al ret.nal t.ick.ess (±SD) measured by.opt.cal coherence t.mography.was 381±99 μm, which was a st.t.st.cally.significant.decrease in comparisonwit. t.e preoperat.ve t.ick.ess (555±112 μm) (P t.onal t.ans-t.non’s ret.obulbar t. infusions were performed in t.n ey.s (50%), due t. t.e recurrence of DME at.6.6±3.0 mont.s aft.r t.e first.t. infusion. At.t.e final examinat.on, macular edema resolved in 13 (65%), improved in four (20%), and remained unchanged in t.ree (15%) of t.e 20 ey.s. At.1 mont. aft.r t.ans-t.non’s ret.obulbar t. infusion, t.e mean laser flare value (±SD) was 9.6±3.0 phot.n/ms, which was a st.t.st.cally.significant.decrease in comparison wit. t.e preoperat.ve value (15.5±5.9 phot.n/ms) (P t.ermore, in t.n ey.s (50%) wit. recurrent.DME, re-elevat.d laser flare values were observed prior t. t.e recurrence of DME. t.e final best.correct.d Snellen visual acuit. improved by.t.o or more lines in nine ey.s (45%), and remained unchanged in 11 ey.s (55.0%). IOP elevat.on equal t. or higher t.an 21 mmHg was observed in t.ree (15%) of t.e 20 ey.s wit. t. infusion, and was cont.olled by.t.pical medicat.ons. No ot.er inject.on-relat.d complicat.ons were observed. Conclusion: t.ans-t.non’s ret.obulbar t. infusion is an effect.ve and safe met.od for t.e t.eat.ent.of refract

关键词：玻璃体切除术球后注射 t.non 曲安奈德糖尿病性黄斑水肿顽固性

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New insight. int. t.e effect. of molecular weight.and end group on t.e t.mperat.re-induced phase t.ansit.on of poly.N-isopropy.acry.amide) in wat.r

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Science China Chemist.y 2013年第1期56卷 56-64页

作者： QIU XingPing koga t.uy.shi t.NAk. Fumihik. WINNIk.Fran oiseM. Depart.ent.of Chemist.y.and Facult. of Pharmacy University of MontrealCP 6128 Succursale Centre VilleMontrealQC H3C 3J7Canada Depart.ent.of Poly.er Chemist.y Graduate School of EngineeringKyoto UniversityKatsuraKyoto 615-8510Japan Inst.t.t. of t.eoret.cal Poly.er Science (It.S) 5-19-2 Ozenji Asao-kuKawasaki 615-8510Japan World Premier Int.rnat.onal (WPI) Research Cent.r Init.at.ve International Center for Materials Nanoarchitectonics (MANA) and National Institute for Materials Science (NIMS)1-1 NamikiTsukuba 305-0044Japan

In an at.empt.t. clarify.issues relat.d t. t.e molecular weight.dependence of t.e phase t.ansit.on of poly.N-isopropy.acry.amide) (PNIPAM) in wat.r,we prepared a library.of PNIPAM samples of well-cont.olled molecular weight.(7000 t. 45000 g/mol) bearing ident.cal groups on each chain *** poly.ers were sy.t.esized by.reversible addit.on-fragment.t.on chain t.ansfer (RAFt. poly.erizat.on of N-isopropy.acry.amide (NIPAM) wit. a bifunct.onal chain t.anfer agent.and furt.er end group *** effect. of t.e end group chemical st.uct.re,hy.roxy.t.y. (HE),propargy. (Pr),chloroet.y. (CE),n-but.l (nBu),n-hexy. (nHe),and isobut.lsulfany.t.iosulfany. (IBS) on t.e phase t.ansit.on t.mperat.re of aqueous PNIPAM solut.ons were invest.gat.d by.high-sensit.vit. different.al scanning calorimet.y.(HS-DSC),y.elding t.e ent.alpy.ΔH and t.e endot.erm maximum t.mperat.re (t.M),and t.rbidimet.y.providing t.e cloud point.(t.CP) of each *** t.CP and t.M of t.e PNIPAM sample of lowest.molar mass (M n 7,000 g/mol,0.5 g/L) ranged,respect.vely.from 38.8 t. 22.5 °C and 42.2 t. 26.0 °C,depending on t.e st.uct.re of t.e end-group,whereas H showed no st.ong end-group *** phase t.ansit.on of all poly.ers,except.-di(n-but.l-PNIPAM),exhibit.d a mark.d dependence on t.e poly.er molar mass.

关键词： poly.N-isopropy.acry.amide) phase t.ansit.on t.mperat.re high-sensit.vit. different.al scanning calorimet.y t.rbidimet.y end group effect

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