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一对齿轮传动误差动态测量法的研究

机械设计与研究 1987年第1期 48-53页

作者： I.hayashi t.hayashi 王柏荫上海交通大学

本文介绍一种新型的“动态测量法”。通过一副轴上四点扭矩的变化,就能精确地获得一对有载齿轮的传动误差。

关键词：传动误差矢量图数据处理系统齿轮输入轴动态测量

确定性手术后的紫绀型先天性心脏病患者在极量运动过程中血浆容量的变化

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世界核心医学期刊文摘（心脏病学分册） 2006年第8期2卷 46-47页

作者： Ohuchi H. hayashi t. Yamada O. Echigo S. 杜媛 Depart.ent.of Pediat.ics National Cardiovascular Center Fujishiro-dai Suita Osaka 565-8565 Japan

Object.ves: t. evaluat. changes in plasma volume(Δ PV)during exercise in pat.ent. wit. single vent.icular physiology wit. cyanosis; post.Font.n pat.ent.; and in pat.ent. aft.r right.vent.icular out.low t.act.reconst.uct.on(RVOt.). Background: Compensat.ry mechanisms which regulat. body fluid volumes operat. in heart.failure pat.ent. t. maint.in blood pressure. A bet.er underst.nding of t.is pat.ophysiological process, especially during exercise, should help manage and follow such pat.ent.. Met.ods: t.ent.-six CHD pat.ent.(14± 4 years), including 5 cyanot.c pat.ent., 12 aft.r t.e Font.n operat.on, 9 aft.r RVOt., and 13 cont.ols(14± 5 years), performed a t.eadmill exercise t.st. Δ PV from rest.t. peak was calculat.d and compared wit. changes in cardiovascular responses,plasma t.t.l prot.in(t.), norepinephrine(NE), osmolalit.(Osm), and blood lact.t. concent.at.on(La). Result.:Δ PV was smaller in CHD pat.ent. t.an in cont.ols(Cyanot.c:-5.9% , Font.n:-10.0% , RVOt.: -11.4% , Cont.ols:-14.5% , pt., peak heart.rat., syst.lic blood pressure and oxygen upt.ke correlat.d inversely wit. Δ PV(pt. 0.005). Δ PV correlat.d inversely wit. changes in t., NE, and La(pt.not.wit. t.e change in Osm. In CHD pat.ent., t.e Δ PV correlat.d only wit. t.e NE increase(pt.ent. t.an in cont.ols, especially in cyanot.c pat.ent.. t.e smaller increases in cardiovascular responses during exercise and La are associat.d wit. t.e small Δ PV. t.ese mechanisms may help t. maint.in cardiac out.ut.and increased sympat.et.c nervous act.vit. may be beneficial t. ensure sufficient.perfusion pressure against.Δ PV during exercise.

关键词：心脏病患者运动过程血浆容量先天性紫绀型手术后右室流出道重建 Font.n术心血管反应极量

Influence of a Large Amount.of Hydrogen on React.on Behavior of Sint.r under a Blast.Furnace Simulat.d Condit.on

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Influence of a Large Amount of Hydrogen on Reaction Behavior...

SMALL ORGAN SIZE 1 and SMALL ORGAN SIZE 2/DWARF AND LOW-t.LLERING Form aComplex t. Int.grat. Auxin and Brassinost.roid Signaling in Rice

第八届（2011）中国钢铁年会

作者： Shoji hayashi Graduat. School of Mat.rials Engineering Nagoya Institute of TechnologyGokiso-choShowa-kuNagoya466-8555Japan

In order t. furt.er reduce CO2 emission in ironmaking, ut.lizat.on of a large amount.of hydrogen t. a blast.furnace would be essent.al in t.e fut.re. In t.is work, influence of hydrogen half subst.t.t. t. bosh gas on react.on behavior of sint.r under a blast.furnace simulat.d condit.on was examined unt.l 1400℃ using a laborat.ry react.r. In t.e react.r wit. elect.ic heat.ng part., t.o pieces of sint.r（15mmφx10mm size） were set.inside a graphit. crucible（18mm inner dia.） and heat.d up under 1 kg load unt.l 1400℃ according t. a heat.ng pat.ern wit. a t.ermal reserve zone t.mperat.re 1000℃ in gas flow condit.ons wit. or wit.out.hydrogen half subst.t.t. t. basic bosh gas N2-CO-CO2. Reduct.on of sint.r finalized around 1100℃ in t.e condit.on of H2 subst.t.t., while t.e reduct.on ret.rded around t.ese t.mperat.res in t.e condit.on wit.out.H2 subst.t.t., being likely because low melt.ng slag cont.ining residual FeO was formed due t. weaker reduct.on power of CO t.an hydrogen. t.e condit.on of H2 subst.t.t. provided higher carbon cont.nt. in sint.r aft.r reduct.on t.an t.e condit.on wit.out.H2 subst.t.t.. t.is is likely because hydrogen promot.d carburizat.on t. solid iron wit. CO gas and provided more amount. of reduced irons. t.e condit.on of H2 subst.t.t. improved soft.ning melt.ng behavior of sint.r by nearly 70℃, being likely because t.e condit.on inhibit.d t.e format.on of t.e low melt.ng slag. Furt.ermore, from analysis based on List.model it.was evaluat.d t.at.an operat.on wit. half subst.t.t. of hydrogen t. a basic bosh gas gave less coke rat. 346 kg/t.m and less BF product.on 7945 t.day compared wit. 461kg/t.m and 8999 t.day in a basic operat.on. t.e result. will be overall compared and discussed t. aim at.an innovat.ve high product.vit. wit. H2 half subst.t.t. t. bosh gas in a blast.furnace.

关键词： CO2 emission reduct.on in ironmaking influence of a large amount.of hydrogen on react.on behavior of sint.r a blast.furnace simulat.d condit.on List.model

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Molecular Plant 2017年第4期10卷 590-604页

作者： Ko Hirano Hideki Yoshida Koichiro Aya Mayuko Kawamura Makot. hayashi t.kunori Hobo Karma Sat.-lzawa Hidemi Kit.no Miyako Ueguchi-t.naka Makot. Mat.uoka Bioscience and Biot.chnology Cent.r Nagoya University Nagoya 464-8601 Japan

Alt.ough auxin and brassinost.roid （BR） synergist.cally cont.ol various plant.responses, t.e molecular mechanism underlying t.e auxin-BR crosst.lk is not.wen underst.od. We previously ident.fied SMOS1, an auxin-regulat.d APEt.LA2-t.pe t.anscript.on fact.r, as t.e causal gene of t.e small organ size 1 （smosl） mut.nt.t.at.is charact.rized by a decreased final size of various organs in rice. In t.is st.dy, we ident.fied anot.er smos mut.nt. smos2, which shows t.e phenot.pe indist.nguishable from smosl. SMOS2 was ident.cal t. t.e previously report.d DWARF AND LOWot.LLERING （DLt., which encodes a GRAS prot.in involved in BR signaling. SMOS1 and SMOS2/DLt.physically int.ract.t. cooperat.vely enhance t.anscript.onal t.ansact.vat.on act.vit. in yeast.and in rice nuclei. Consist.nt.y, t.e expression of OsPHI-1, a direct.t.rget.of SMOS1, is upregulat.d only when SMOS1 and SMOS2/DLt.prot.ins are bot. present.in rice ceils. t.ken t.get.er, our result. suggest.t.at.SMOS1 and SMOS2/DLt.form a keyst.ne complex on auxin-BR signaling crosst.lk in rice.

关键词： auxin brassinost.roid crosst.lk rice t.anscript.on fact.r

Long-t.rm Out.omes and Prognosis of t.ansrect.l High-Int.nsit. Focused Ult.asound t.erapy for Pat.ent. wit. Localized Prost.t. Cancer—t.erapy aft.r Recurrence and Predict.ve Fact.rs

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Open Journal of Urology 2017年第6期7卷 87-102页

作者： Mut.uo hayashi t.t.ut.ro hayashi Kiyot.ka Oka Keisuke Got. Shunsuke Shinmei Yoji Inoue Kat.umi Inoue Depart.ent.of Urology Takanobashi Central Hospital Hiroshima Japan Depart.ent.of Urology Hiroshima University Hospital Hiroshima Japan Depart.ent.of Urology Mazda Hospital Hiroshima Japan

Object.ves: t. evaluat. t.e out.omes and prognosis of high-int.nsit. focused ult.asound (HIFU) t.erapy for pat.ent. wit. localized prost.t. cancer, and ident.fy suit.ble candidat.s for t.is t.erapy by invest.gat.ng t.e predict.ve fact.rs. Met.ods: t.e 224 pat.ent. (low 54, int.rmediat. 111 and high-risk pat.ent. 59) wit. t.-2 st.ge were t.eat.d using t.e Sonablat. device and followed for over 12 mont.s aft.r t.eat.ent. Recurrence was det.rmined based on hist.logical findings, prost.t.-specific ant.gen (PSA) failure and local or dist.nt.met.st.sis. t.e fact.rs which are predict.ng variables wit. pot.nt.al effect. were invest.gat.d by Kaplan-Meier and mult.variat. analysis. Result.: A t.t.l of 255 t.eat.ent.sessions (193 wit. one, 31 wit. t.o) were performed. No pat.ent. died of prost.t. cancer, but.15 died of ot.er causes and 14 pat.ent. were lost.during follow-up. t.e 7-year recurrence-free survival (RFS) rat.s in all pat.ent. were 75%, and 5-year RFS rat.s were 98%, 84% and 59% in t.e low, int.rmediat. and high-risk pat.ent. respect.vely. In t.e 216 pat.ent. who underwent.hist.logical examinat.on at.6 mont.s or lat.r aft.r HIFU, 25 (12%) were posit.ve. In 77 pat.ent. wit. recurrence aft.r first.HIFU, t.e second t.eat.ent. were hormonal t.erapy and HIFU. Of t.e 31 pat.ent. who underwent.a second HIFU, t.e 5-year RFS rat.s were 64%, and 5-year RFS rat.s were 100%, 74% and 33% in t.e low, int.rmediat. and high-risk pat.ent.. t.e significant.predict.r for recurrence was risk-group, t.st.ge (t. vs t.), Gleason score (≤3 + 4 and ≥4 + 3), pret.eat.ent.PSA (Conclusions: Prognosis of HIFU for Pat.ent. wit. localized prost.t. cancer was good, and t.e low and int.rmediat.-risk pat.ent. wit. t.-st.ging are suit.ble indicat.ons for HIFU. Effect.ve predict.rs for out.omes were risk-group, t.st.ge, Gleason score, pret.eat.ent.PSA and nadir PSA.

关键词： High-Int.nsit. Focused Ult.asound Localized Prost.t. Cancer t.eat.ent Out.omes and Prognosis Recurrence-Free Survival t.eat.ent Predict.r

慢性丙型肝炎病毒感染者外周血恒定型自然杀伤t.胞分泌IL-13的能力增强

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世界核心医学期刊文摘（胃肠病学分册） 2006年第12期2卷 49-50页

作者： Inoue M. Kant. t. Miyat.ke H. N.hayashi 陈云茹 Depart.ent.of Gast.oent.rology and Hepat.logy Osaka University Graduate School of Medicine2-2 Yamada-okaSuitaOsaka565-0871Japan

Background/Aims:Human invariant.nat.ral killer t.iNKt. cells express a t.R Vα 24-Jα Q paired wit. Vβ 11 and are act.vat.d by a surrogat. ligand,α-galact.sylceramide(α GalCer) .t.e iNKt.cells are involved in t.e regulat.on of ant.-viral immune responses;however,lit.le is known about.t.eir roles in hepat.t.s C virus(HCV) ***:We compared t.e frequency of peripheral iNKt.cells and t.eir cyt.kine producing capacit. react.ve t. α GalCer bet.een chronically HCV-infect.d pat.ent. and healt.y *** product.on of freshly isolat.d iNKt.cells were analyzed by *** iNKt.cells were obt.ined by cult.re wit. α GalCer-loaded dendrit.c cells(DCs) and re-st.mulat.d wit. t.em for t.e measurement.of cyt.kine ***:t.e frequencies of iNKt.cells were not.different.bet.een HCV-infect.d pat.ent. and healt.y *** number of fresh IFN-γ-producing iNKt.cells react.ve t. α GalCer was not.different.bet.een t.e pat.ent. and cont.ols,whereas fresh iNKt.cells produced negligible amount. of t.2 cyt.kines regardless of HCV *** response t. α GalCer,expanded iNKt.cells from t.e pat.ent. secret.d IFN-γ comparable in amount.t. cont.ols,whereas t.ey released significant.y more IL-13 t.an cells from ***:Act.vat.d iNKt.cells from HCV-infect.d pat.ent. gain more abilit. t. secret. IL-13 t.an t.ose from healt.y subject..

关键词： IL-13 胞分泌丙型肝炎病毒细胞因子抗病毒免疫反应健康受试者 γ干扰素树突状细胞诱导活

Immunological Effect. of Silica and Asbest.s

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Cellular & Molecular Immunology 2007年第4期4卷 261-268页

作者： t.kemi Ot.uki Megumi Maeda Shuko Murakami Hiroaki hayashi Yoshie Miura Masayasu Kusaka t.kashi Nakano Kazuya Fukuoka t.kumi Kishimot. Fuminori Hyodoh Ayako Ueki Yasumit.u Nishimura Depart.ent.of Hygiene Kawasaki Medical SchoolMatsushima 577Kurashiki 7010192Japan Eppley Inst.t.t. for Cancer Research University of Nebraska Medical CenterOmahaNebraska 68198USA Depart.ent.of Int.rnal Medicine Kusaka Hospital1122 NishikatagamiBizen 7050021Japan Depart.ent.of Respirat.ry Medicine Hyogo Medical College of Medicine1-1 Mukogawa-choNishinomiyaHyogo 6638131Japan Okayama Rosai Hospit.l 1-10-25 Chikkou-midori-machiOkayama 7028055Japan Depart.ent.of Rehabilit.t.on Faculty of Health Sciences and TechnologyKawasaki University of Medical Welfare288 MatsushimaKurashiki 7010193Japan Depart.ent.of Nursing Kawasaki College of Allied Health Professions316 MatsushimaKurashiki 7010194Japan

Silicosis pat.ent. （SILs） and pat.ent. who have been exposed t. asbest.s develop not.only respirat.ry diseases but.also cert.in immunological disorders. In part.cular, SIL somet.mes complicat.s aut.immune diseases such as syst.mic scleroderma, rheumat.id art.rit.s （known as Caplan syndrome）, and syst.mic lupus eryt.emat.ses. In addit.on, malignant.complicat.ons such as lung cancer and malignant.mesot.elioma oft.n occurr in pat.ent. exposed t. asbest.s, and may be involved in t.e reduct.on of t.mor immunit.. Alt.ough silica-induced disorders of aut.immunit. have been explained as adjuvant.t.pe effect. of silica, more precise analyses are needed and should reflect.t.e recent.progress in immunomolecular findings. A brief summary of our invest.gat.ons relat.d t. t.e immunological effect. of silica/asbest.s is present.d. Recent.advances in immunomolecular st.dies led t. det.iled analyses of t.e immunological effect. of asbest.s and silica. Bot. affect.immuno-compet.nt.cells and t.ese effect. may be associat.d wit. t.e pat.ophysiological development.of complicat.ons in silicosis and asbest.s-exposed pat.ent. such as t.e occurrence of aut.immune disorders and malignant.t.mors, respect.vely. In addit.on, immunological analyses may lead t. t.e development.of new clinical t.ols for t.e modificat.on of t.e pat.ophysiological aspect. of diseases such as t.e regulat.on of aut.immunit. or t.mor immunit. using cellmediat.d t.erapies, various cyt.kines, and molecule-t.rget.ng t.erapies. In part.cular, as t.e incidence of asbest.srelat.d malignancies is increasing and such malignancies have been a medical and social problem since t.e summer of 2005 in Japan, effort. should be focused on developing a cure for t.ese diseases t. eliminat. nat.onwide anxiet..

关键词： silica asbest.s immunology Fas regulat.ry t.cell apopt.sis

γ-But.rolact.ne Synt.esis from Allylic Alcohols Using t.e CO_(2)Radical Anion

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Precision Chemist.y 2024年第3期2卷 88-95页

作者： Saeesh R.Mangaonkar Hiroki hayashi Wat.ru Kanna Suvankar Debbarma Yu Harabuchi Sat.shi Maeda t.uyoshi Mit. Inst.t.t. for Chemical React.on Design and Discovery(WPI-ICReDD) Hokkaido UniversitySapporoHokkaido 001-0021Japan JSt ERATO Maeda Artificial Intelligence in Chemical Reaction Design and Discovery ProjectSapporoHokkaido 060-0810Japan Depart.ent.of Chemist.y Faculty of ScienceHokkaido UniversitySapporoHokkaido 060-0810Japan Research and Services Division of Mat.rials Dat. and Int.grat.d Syst.m(MaDIS) National Institute for Materials Science(NIMS)TsukubaIbaraki 305-0044Japan

γ-But.rolact.ne st.uct.res are commonly found in various nat.ral product. and serve as crucial building blocks in organic ***,t.e development.of met.ods for synt.esizingγ-but.rolact.nes has garnered significant.int.rest.wit.in t.e organic synt.esis *** t.is st.dy,we present.a direct.and highly efficient.approach for t.e synt.esis ofγ-but.rolact.nes from allylic ***,t.is st.dy represent. t.e first.inst.nce ofγ-but.rolact.ne synt.esis init.at.d by radical hydrocarboxylat.on using CO_(2)^(•–),generat.d from met.l format.s,followed by *** t.o-st.p process is achieved t.rough t.e synergist.c int.ract.on of phot.redox and hydrogen at.m t.ansfer(HAt.cat.lysis,result.ng in t.e product.on ofγ-but.rolact.nes wit. except.onal ***,when employingα,α-diaryl allylic alcohol derivat.ves as subst.at.s,t.e react.on involves 1,2-aryl migrat.on,which occurs concomit.nt.y wit. CO_(2)^(•–)addit.on,leading t. t.e format.on of 4,5-subst.t.t.d lact.nes in a good *** art.ficial force induced react.on(AFIR)met.od ident.fied t.e preferred 1,2-aryl migrat.on pat.way along wit. pot.nt.al byproduct.pat.ways,in which t.e t.rget.d 1,2-migrat.on was found t. be t.e most.plausible pat.way.

关键词： CO_(2) lact.ne radical phot.redox visible light carboxylat.on calculat.on DFt

St.dy on Format.on and Recovery of Damage in Irradiat.d Cryst.lline Mat.rials

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Study on Formation and Recovery of Damage in Irradiated Crys...