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High-Pe.formance.and Large.Are. Inve.t.d Pe.ovskit. Solar Ce.ls Base. on NiO_(x) Films e.able. wit. A Nove. microst.uct.re.Cont.ol t.chnology

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e.e.gy & e.vironme.t.l mat.rials 2024年第1期7卷 153-159页

作者： Guibin She. Xin Li Yuqin Zou Hongye.Dong Dongping Zhu Yanglin Jiang Xin Re. Ng Fe. Lin Pe.0}r m.ller-Buschbaum Che.g mu Ke. Laborat.ry of Advance. Light.Conve.sion mat.rials and Biophot.nics Department of ChemistryRenmin University of ChinaBeijing 100872China Solar e.e.gy Re.e.rch Inst.t.t. of Singapore.Se.IS) National University of SingaporeSingapore 117574Singapore Physik-De.art.e.t Lehrstuhl für Funktionelle MaterialienTechnische Universität MünchenJames-Franck-Straße 185748Garching Germany He.nz maie.-Le.bnit. Ze.t.um(mLZ) Technische Universität MünchenLichtenbergstr.185748Garching Germany

t.e.improve.e.t.in t.e.e.ficie.cy of inve.t.d pe.ovskit. solar ce.ls(PSCs)is significant.y limit.d by unde.irable.cont.ct.at.t.e.NiO_(x)/pe.ovskit. *** t.is st.dy,a nove. microst.uct.re.cont.ol t.chnology is propose. for fabricat.on of porous NiO_(x)films using Pluronic P123 as t.e.st.uct.re.dire.t.ng age.t.and ace.0}lace.0}ne.AcAc)as t.e.coordinat.on *** synt.e.ize. porous NiO_(x)films e.hance. t.e.hole.e.t.act.on e.ficie.cy and re.uce. re.ombinat.on de.e.t. at.t.e.NiO_(x)/pe.ovskit. ***,wit.out.any modificat.on,t.e.powe. conve.sion e.ficie.cy(PCe.of t.e.PSC wit. mAPbl_(3)as t.e.absorbe. laye. improve. from 16.50%t. 19.08%.more.ve.,t.e.PCe.of t.e.de.ice.compose. of pe.ovskit. Cs0.05(mA_(0.15)FA_(0.85))_(0.95)Pb(I_(0.85)Br_(0.15))_(3)improve. from 17.49%t. 21.42%.Furt.e.more.t.e.applicat.on of t.e.fabricat.d porous NiO_(x)on fluorine.dope. t.n oxide.Ft.)subst.at.s e.able. t.e.fabricat.on of large.are. PSCs(1.2 cm^(2))wit. a PCe.of 19.63%.t.is st.dy provide. a nove. st.at.gy for improving t.e.cont.ct.at.t.e.NiO_(x)/pe.ovskit. int.rface.for t.e.fabricat.on of high-pe.formance.large.are. pe.ovskit. solar ce.ls.

关键词： int.rfacial cont.ct inve.t.d and large.are. pe.ovskit. solar ce.ls phot.volt.ic mat.rials porous NiO_(x)films re.e.able.e.e.gy

Impact.of de.ice.re.ist.nce. in t.e.pe.formance.of graphe.e.base. t.rahe.t. phot.de.0}ct.rs

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Front.e.s of Opt.e.e.t.onics 2024年第2期17卷 87-97页

作者： O.Cast.lló Sofía m.Lópe. Bapt.st. K.Wat.nabe.t.t.niguchi e.Die. J.e.Ve.ázque.-Pére. Y.m.me.iani J.m.Caridad J.A.De.gado-Not.rio De.art.e.t.of Applie. Physics University of Salamanca37008 SalamancaSpain Unidad de.e.ce.e.cia e. Luz y mat.ria e.t.uct.rada(LUme.) University of Salamanca37008 SalamancaSpain Re.e.rch Ce.t.r for e.e.t.onic and Opt.cal mat.rials National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Re.e.rch Ce.t.r for mat.rials Nanoarchit.ct.nics National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Nanot.chnology Group USAL-NanolabUniversity of Salamanca37008 SalamancaSpain

In re.e.t.ye.rs,graphe.e.fie.d-e.fe.t.t.ansist.rs(GFe.0})have.de.onst.at.d an out.t.nding pot.nt.al for t.rahe.t.(t.z)phot.de.0}ct.on due.t. t.e.r fast.re.ponse.and *** fe.t.re. are.e.se.t.al t. e.able.e.e.ging t.z applicat.ons,including 6G wire.e.s communicat.ons,quant.m informat.on,bioimaging and ***,t.e.ove.all pe.formance.of t.e.e.phot.de.0}ct.rs may be.ut.e.ly compromise. by t.e.impact.of int.rnal re.ist.nce. pre.e.t.d in t.e.de.ice.so-calle. acce.s or parasit.c *** t.is work,we.provide.a de.0}ile. st.dy of t.e.influe.ce.of int.rnal de.ice.re.ist.nce. in t.e.phot.re.ponse.of high-mobilit. dual-gat. GFe.0}*** dual-gat. archit.ct.re. allow us t. fine.t.ne.de.re.se.t.e.int.rnal re.ist.nce.of t.e.de.ice.by an orde. of magnit.de.and conse.ue.t.y de.onst.at. an improve. re.ponsivit. and noise.e.uivale.t.powe. value. of t.e.phot.de.0}ct.r,*** re.ult. can be.we.l unde.st.od by a se.ie. re.ist.nce.mode.,as shown by t.e.e.ce.le.t.agre.me.t.found be.0}e.n t.e.e.pe.ime.t.l dat. and t.e.re.0}cal *** findings are.t.e.e.ore.re.e.ant.t. unde.st.nd and improve.t.e.ove.all pe.formance.of e.ist.ng high-mobilit. graphe.e.phot.de.0}ct.rs.

关键词： Graphe.e t.z Phot.de.0}ct.r Fie.d-e.fe.t.t.ansist.r Plasmonic

Dist.ibut.on, he.lt. and e.ological risk asse.sme.t. of t.ace.e.e.e.t. in Nige.ian oil sands

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Act. Ge.chimica 2024年第1期43卷 59-71页

作者： Odunayo t.Ore.Fe.t.s m.Ade.iyi De.art.e.t.of Che.ist.y Obafemi Awolowo UniversityIle-Ife 220005Nigeria De.art.e.t.of Che.ical Scie.ce. Achievers UniversityOwoNigeria

t.e.Nige.ian oil sands re.re.e.t.t.e.large.t.oil sand de.osit.in Africa, ye.0}t.e.e.is lit.le.publishe. informat.on on t.e.dist.ibut.on and pot.nt.al he.lt. and e.ological risks of t.ace.e.e.e.t. in t.e.oil re.ource. In t.e.pre.e.t.st.dy, we.inve.t.gat.d t.e.dist.ibut.on pat.e.n of 18t.ace.e.e.e.t.(including biophile.and chalcophile.e.e.e.t.) as we.l as t.e.e.t.mat.d risks associat.d wit. e.posure.t. t.e.e.e.e.e.t.. t.e.re.ult. of t.e.st.dy indicat.d t.at.Fe.was t.e.most.abundant.e.e.e.t. wit. a me.n conce.t.at.on of 22,131 mg/kg while.Br had t.e.lowe.t.me.n conce.t.at.on of 48 mg/kg. t.e.high occurre.ce.of Fe.and t. sugge.t.d a possible.occurre.ce.of ilme.it.(Fe.t.O_(3)) in t.e.oil sands. Source.apport.onme.t.using posit.ve.mat.ix fact.rizat.on showe. t.at.t.e.possible.source. of de.0}ct.d e.e.e.t. in t.e.oil sands we.e.ge.ge.ic, me.0}l product.on, and crust.l. t.e.cont.minat.on fact.r, ge.-accumulat.on inde., modifie. de.re. of cont.minat.on, pollut.on load inde., and Ne.e.ow pollut.on inde. indicat.d t.at.t.e.oil sands are.he.vily pollut.d by t.e.e.e.e.t.. He.lt. risk asse.sme.t.showe. t.at.childre. we.e.re.at.ve.y more.susce.t.ble.t. t.e.pot.nt.ally t.xic e.e.e.t. in t.e.oil sands principally via inge.t.on e.posure.rout.(HQ > 1e.04). Cance. risks from inhalat.on are.unlike.y due.t. CR e.06 but.inge.t.on and de.mal cont.ct.pose.se.e.e.risks(CR > 1e.04). t.e.high conce.t.at.ons of t.e.e.e.e.t. pose.se.ious t.re.t. due.t. t.e.pot.nt.al for at.osphe.ic t.ansport. bioacce.sibilit., and bioavailabilit..

关键词： Biophile Chalcophile Oil sand Risk asse.sme.t t.ace.e.e.e.t

Ne. t.e.ds in diagnosis and manage.e.t.of gallbladde. carcinoma

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World Journal of Gast.oint.st.nal Oncology 2024年第1期16卷 13-29页

作者： e.st.t.ios t.Pavlidis Ioannis N Galanis t.e.doros e.Pavlidis ^(nd)Prope.e.t.c De.art.e.t.of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Gallbladde.(GB)carcinoma,alt.ough re.at.ve.y rare.is t.e.most.common biliary t.e. cholangiocarcinoma wit. aggre.sive.e.s and poor *** is close.y associat.d wit. chole.it.iasis and long-st.nding large.>3 cm)gallst.ne. in up t. 90%of *** ot.e. main pre.isposing fact.rs for GB carcinoma include.mole.ular fact.rs such as mut.t.d ge.e.,GB wall calcificat.on(porce.ain)or mainly mucosal microcalcificat.ons,and GB polyps≥1 cm in *** is made.by ult.asound,comput.d t.mography(Ct.,and,more.pre.ise.y,magne.0}c re.onance.imaging(mRI).Pre.pe.at.ve.st.ging is of gre.t.import.nce.in de.isionmaking re.arding t.e.ape.t.c *** st.ging is base. on mRI findings,t.e.le.ding t.chnique.for live. me.0}st.sis imaging,e.hance. t.re.-phase.Ct.angiography,or magne.0}c re.onance.angiography for major ve.se. *** is also ne.e.sary t. use.posit.on e.ission t.mography(Pe.0}-Ct.or ^(18)F-FDG Pe.0}mRI t. more.accurat.ly de.0}ct.me.0}st.se. and any ot.e. occult.de.osit. wit. act.ve.me.0}bolic *** laparoscopy may de.0}ct.disse.inat.on not.ot.e.wise.found in 20%-28.6%of *** t.e.t.e.t.is ne.de.,including surgical re.e.t.on,t.rge.0}d t.e.apy by biological age.t. according t. mole.ular t.st.ng ge.e.mapping,che.ot.e.apy,radiat.on t.e.apy,and *** is of gre.t.import.nce.t. unde.st.nd t.e.updat.d guide.ine. and curre.t.t.e.t.e.t.*** e.t.nt.of surgical int.rve.t.on de.e.ds on t.e.dise.se.st.ge.ranging from simple.chole.yst.ct.my(t.a)t. e.t.nde. re.e.t.ons and including e.t.nde. chole.yst.ct.my(t.b),wit. wide.lymph node.re.e.t.on in e.e.y case.or IV-V se.me.t.ct.my(t.),he.at.c t.ise.me.t.ct.my or major he.at.ct.my accompanie. by he.at.coje.unost.my Roux-Y,and adjace.t.organ re.e.t.on if ne.e.sary(t.).Laparoscopic or robot.c surge.y shows fe.e. post.pe.at.ve.complicat.ons and e.uivale.t.oncological out.ome. whe. compare. t. ope. surge.y,but.much at.e.t.on must.be.paid t. avoiding *** addit.on t. surge.y,nove. t.rge

关键词： Biliary t.act.ne.plasms e.t.ahe.at.c cholangiocarcinoma Gallbladde. carcinoma Gallbladde. dise.se. Biliary t.e. dise.se. Gast.oint.st.nal malignancie.

manage.e.t.of obst.uct.d colore.t.l carcinoma in an e.e.ge.cy se.0}ing:An updat.

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World Journal of Gast.oint.st.nal Oncology 2024年第3期16卷 598-613页

作者： e.st.t.ios t.Pavlidis Ioannis N Galanis t.e.doros e.Pavlidis 2nd Prope.e.t.c De.art.e.t.of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colore.t.l carcinoma is common,part.cularly on t.e.le.t.*** 20%of pat.e.t.,obst.uct.on and ile.s may be.t.e.first.clinical manife.t.t.ons of a carcinoma t.at.has advance.(st.ge.II,III or e.e. IV).Diagnosis is base. on clinical pre.e.t.t.on,plain abdominal radiogram,comput.d t.mography(Ct.,Ct.colonography and posit.on e.ission t.mography/*** be.t.manage.e.t.st.at.gy in t.rms of short.t.rm ope.at.ve.or int.rve.t.onal and long-t.rm oncological out.ome. re.mains *** t.e.most.common le.t.side. obst.uct.on,t.e.first.choice.should be.e.t.e. e.e.ge.cy surge.y or e.doscopic de.ompre.sion by se.f-e.pe.-dable.me.0}l st.nt. or *** ope.at.ve.plan should be.e.t.e. one.st.ge.or t.o-st.ge.***-st.ge.re.e.t.on wit. on-t.ble.bowe. de.ompre.sion and irrigat.on can be.accompanie. or not.accompanie. by proximal de.unct.oning st.ma(colost.my or ile.st.my).Primary anast.mosis is more.conve.ie.t.but.has incre.se. risks of anast.mot.c le.kage.and ***-st.ge.re.e.t.on(Hart.mann’s proce.ure.is safe. and t.e.most.wide.y use. de.pit. t.mporally affe.t.ng qualit. of *** cont.ol surge.y in high-risk frail pat.e.t. is le.s fre.ue.t.y pe.forme. since.it.can be.succe.sfully subst.t.t.d wit. e.doscopic st.nt.ng or *** t.e.le.s common right.side. obst.uct.on,one.st.ge.surgical re.e.t.on is more.be.e.icial t.an e.doscopic *** role.of minimally invasive.surge.y(laparoscopic or robot.c)is a subje.t.of *** laparoscopic-assist.d manage.e.t.is advant.ge.us t. some.e.t.nt.but.re.uire. much e.pe.t.se.due.t. inhe.e.t.difficult.e. in disse.t.ng t.e.dist.nde. colon and t.e.risk of rup-t.re.and subse.ue.t.se.t.c *** de.ompre.sing st.nt.as a bridge.t. e.e.t.ve.surge.y more.subst.nt.ally de.re.se. t.e.risks of morbidit. and mort.lit. t.an e.e.ge.cy surge.y for de.ompre.sion and has e.uivale.t.me.ium-t.rm ove.all survival and dise.se.fre. survival *** combinat.on wit. ne.adjuvant.che.ot.e.apy or radiat.on may have.a p

关键词： Acut. abdome. Obst.uct.ve.ile.s Colore.t.l carcinoma e.e.ge.cy surge.y Cole.t.my Int.aluminal me.0}l st.nt.

Conve.t.ng t.e.-RGB gre.n-channe. dat. t. 557.7 nm auroral int.nsit.:me.0}odology and init.al re.ult.

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e.rt. and Plane.0}ry Physics 2024年第1期8卷 258-274页

作者： Jun Liang D.m.Gillie. e.Spanswick e.F.Donovan Unive.sit. of Calgary CalgaryT2N 1N4Canada

t.e.re.e.t.y de.loye. t.ansit.on Re.ion e.plore.(t.e.)-RGB(re.-gre.n-blue.all-sky image.(ASI)is de.igne. t. capt.re.t.ue.color”image. of t.e.aurora and *** t.e.557.7 nm gre.n line.is usually t.e.bright.st.e.ission line.in visible.auroras,t.e.gre.n channe. of a t.e.-RGB came.a is usually dominat.d by t.e.557.7 nm *** t.is rat.onale.t.e.t.e. mission doe. not.include.a spe.ific 557.7 nm image. and is de.igne. t. use.t.e.RGB gre.n-channe. dat. as a proxy for t.e.557.7 nm *** t.is st.dy,we.pre.e.t.an init.al e.fort.t. e.t.blish t.e.conve.sion rat.o or formula linking t.e.RGB gre.n-channe. dat. t. t.e.absolut. int.nsit. of 557.7 nm auroras,which is crucial for quant.t.t.ve.use. of t.e.RGB *** illust.at. t.o approache.:(1)t.rough a comparison wit. t.e.collocat.d me.sure.e.t.of gre.n-line.auroras from t.e.t.e. spe.t.ograph,and(2)t.rough a comparison wit. t.e.mode.e. gre.n-line.int.nsit. according t. re.list.c e.e.t.on pre.ipit.t.on flux me.sure.e.t. from low-e.rt.-orbit.sat.llit.s,wit. t.e.aid of an auroral t.ansport.*** de.onst.at. t.e.proce.ure. and provide.init.al re.ult. for t.e.t.e.-RGB ASIs at.t.e.Rabbit.Lake.and Lucky Lake.*** RGB re.ponse.is found t. be.*** conve.sion rat.os or formulas be.0}e.n RGB gre.n-channe. dat. and t.e.gre.n-line.auroral int.nsit. are.give. and can be.applie. imme.iat.ly by t.e.-RGB dat. *** me.0}odology e.t.blishe. in t.is st.dy will also be.applicable.t. t.e.upcoming SmILe.ASI mission,which will adopt.a similar RGB came.a syst.m in it. de.loyme.t.

关键词： t.e. RGB gre.n-line.aurora auroral t.ansport.mode.

Hydroxyapat.t. composit.s wit. carbon allot.ope.:Pre.arat.on,prope.t.e.,and applicat.ons

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Part.cuology 2024年第5期88卷 239-265页

作者： Boris I.Kharisov Oxana V.Kharissova Lucy t.Gonzále. Yolanda Pe.a ménde. Igor e.Uflyand Idalia Góme. de.la Fue.t. Unive.sidad Aut.noma de.Nue.o Le.n Ave.UniversidadCiudad UniversitariaSan Nicolás de los GarzaNuevo León 66455Mexico t.cnologico de.mont.rre. Escuela de Ingeniería y CienciasMonterreyNuevo Leon 64890Mexico De.art.e.t.of Che.ist.y Southern Federal UniversityRostov-on-DonRussia

Hydroxyapat.t.(HA)and it. composit.s wit. inorganic addit.ve.,dopant.,and polyme.s is a rapidly de.e.oping branch in t.e.mat.rials *** part.cular,carbon allot.ope. are.wide.y use. in t.e.e.composit.s be.ng wide.y applie. for me.ical *** a gap of insufficie.t.ge.e.alizat.on of re.e.t.achie.e.e.t. in t.e.fie.d of t.e.HA/Carbon composit.s,in t.is re.ie. we.pre.e.t.t.e.st.t. of t.e.art.of t.e.fie.d of HA composit.s and hybrids wit. classic carbon allot.ope. and *** composit.s are.known for carbon nanot.be.,nanofibe.s,graphe.e.and it. oxidize. forms,as we.l as,in a le.se. grade.for graphit.,fullere.e.,nanodiamonds,carbon nanofoams,*** composit.s can be.fabricat.d by a varie.0} of classic and le.s-common me.0}ods,such as co-pre.ipit.t.on(wit. or wit.out.ult.asonic t.e.t.e.t.,CVD,hot.isost.t.c pre.sing,hydrot.e.mal,spark plasma sint.ring,biomime.0}c mine.alizat.on,t.e.mal and plasma spray,e.e.t.oche.ical and e.e.t.ophore.0}c de.osit.on,se.f-asse.bling,3D print.ng,e.e.t.ospinning,and lyophilisat.on,among *** of various synt.e.is t.chnique. can be.also carrie. out.for composit. *** or synt.e.0}c HA can be.use. as it.is for furt.e. int.ract.on wit. carbon allot.ope. or it.can be.first.pre.are. and t.e. re.ct.d wit. carbon count.rpart.similarly,carbon allot.ope. can be.int.oduce. int. t.e.int.ract.on wit. HA dire.t.y or t.e. can be.first.synt.e.ize.,in part.cular from *** biocompat.ble.composit.s can be.produce. in t.e.form of coat.ngs,powde.s,and scaffolds and can addit.onally cont.in quant.t.t.ve.amount. of t.ird phase.,fre.ue.t.y nat.ral or synt.e.0}c *** t.e.e.composit.s,e.pe.ially wit. O-cont.ining funct.onalizing groups,HA disadvant.ge. could be.conside.ably de.re.se. wit. simult.ne.us e.hance.e.t.of me.hanical prope.t.e.,be.oming similar t. human bone.che.ical st.bilit. and biocompat.bilit.,as we.l as posse.sing ant.bact.rial ***→G re.uct.on and highe. HA de.orat.on we.e.obs

关键词： Hydroxyapat.t. Carbon nanot.be. Graphe.e Quant.m dot. Fullere.e. Nanodiamonds

Curre.t.conside.at.ons on int.aduct.l papillary ne.plasms of t.e.bile.duct.and pancre.t.c duct

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World Journal of Gast.oe.t.rology 2024年第10期30卷 1461-1465页

作者： e.st.t.ios t.Pavlidis Ioannis N Galanis t.e.doros e.Pavlidis 2^(nd) Prope.e.t.c De.art.e.t.of Surge.y Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Pancre.t.biliary int.aduct.l papillary ne.plasms(IPNs)re.re.e.t.pre.ursors of pancre.t.c cance. or bile.duct.cholangiocarcinoma t.at.can be.de.0}ct.d and *** advance. in diagnost.c me.0}ods,ide.t.fying t.e.e.pre.alignant.le.ions is st.ll challe.ging for t.e.t.e.t.*** imaging,biomarke.s and mole.ular t.st. for ge.omic alt.rat.ons can be.use. for diagnosis and *** int.rve.t.on in combinat.on wit. ne. che.ot.e.ape.t.c age.t. is conside.e. t.e.opt.mal t.e.t.e.t.for malignant.*** balance.be.0}e.n t.e.risk of malignancy and any risk of re.e.t.on guide. manage.e.t.policy;t.e.e.ore.t.e.t.e.t.should be.individualize. base. on a me.0}culous pre.pe.at.ve.asse.sme.t.of high-risk *** of t.e.bile.duct.is more.aggre.sive.t.us,e.rly diagnosis and surge.y are.*** conse.vat.ve.manage.e.t.of low-risk pancre.t.c branch-duct.le.ions is safe.and e.fe.t.ve.

关键词： Biliary t.e. dise.se. Pancre.t.c cyst.c ne.plasms Biliary t.act.ne.plasms e.t.ahe.at.c cholangiocarcinoma Pancre.t.c ade.ocarcinoma

Re.ode.ing t.mor Immune.microe.vironme.t.by Using Polyme.-Lipid-mangane.e.Dioxide.Nanopart.cle. wit. Radiat.on t.e.apy t. Boost.Immune.Re.ponse.of Cast.at.on-Re.ist.nt.Prost.t. Cance.

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Re.e.rch 2024年第3期2023卷 83-96页

作者： Abdulmot.ale. e.Ze.0}ini HoYin Lip Azhar Z.Abbasi Ibrahim Alradwan t.ksim Ahme. Chunshe.g He.Je.fre. t.He.de.son Andre. m.Raut. Xiao Yu Wu Advance. Pharmace.t.cs and Drug De.ive.y Laborat.ry Leslie Dan Faculty of PharmacyUniversity of TorontoM5S 3M2TorontoONCanada. De.art.e.t. of me.ical Biophysics and Radiat.on Oncology University of TorontoM5G 1L7TorontoONCanada.

De.pit. subst.nt.al progre.s in t.e.t.e.t.e.t.of cast.at.on-re.ist.nt.prost.t. cance. (CRPC), including radiat.on t.e.apy and immunot.e.apy alone.or in combinat.on, t.e.re.ponse.t. t.e.t.e.t.re.ains poor due.t. t.e.hypoxic and immunosuppre.sive.nat.re.of t.e.t.mor microe.vironme.t. He.e.n, we.e.ploit.d t.e.biore.ct.vit. of nove. polyme.–lipid mangane.e.dioxide.nanopart.cle. (PLmDs) t. re.ode. t.e.t.mor immune.microe.vironme.t.(t.me. by incre.sing t.e.local oxyge. le.e.s and e.t.ace.lular pH and e.hancing radiat.on-induce. immunoge.ic ce.l de.t.. t.is st.dy de.onst.at.d t.at.PLmD t.e.t.e.t.se.sit.ze. hypoxic human and murine.CRPC ce.ls t. radiat.on, significant.y incre.sing radiat.on-induce. DNA double.st.and bre.ks and ult.mat.ly ce.l de.t., which e.hance. t.e.se.re.0}on of damage.associat.d mole.ular pat.e.ns, at.ribut.ble.t. t.e.induct.on of aut.phagy and e.doplasmic re.0}culum st.e.s. Re.xyge.at.on via PLmDs also polarize. hypoxic murine.RAW264.7 macrophage. t.ward t.e.m1 phe.ot.pe. e.hancing t.mor ne.rosis fact.r alpha re.e.se. and t.us re.ucing t.e.viabilit. of murine.CRPC t.AmP-C2 ce.ls. In a synge.e.c t.AmP-C2 t.mor mode., int.ave.ous inje.t.on of PLmDs suppre.se., while.radiat.on alone.e.hance. re.ruit.e.t.of re.ulat.ry t.ce.ls and mye.oid-de.ive. suppre.sor ce.ls. Pre.0}e.t.e.t.wit. PLmDs followe. by radiat.on down-re.ulat.d programme. de.t.-ligand 1 and promot.d t.e.infilt.at.on of ant.t.mor CD8+ t.ce.ls and m1 macrophage. t. t.mor sit.s. t.ke. t.ge.0}e., t.me.modulat.on by PLmDs plus radiat.on profoundly de.aye. t.mor growt. and prolonge. me.ian survival compare. wit. radiat.on alone. t.e.e.re.ult. sugge.t.t.at.PLmDs plus radiat.on is a promising t.e.t.e.t.modalit. for improving t.e.ape.t.c e.ficacy in radiore.ist.nt.and immunosuppre.sive.solid t.mors.

关键词： RAW264.7 alone t.e.t.e.t