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Bioact.ve compounds from marine St.ept.myces sp. VIt.SA as t.erapeut.cs

Front.ers in Biology 2017年第4期12卷 280-289页

作者： S. Pooja t. aditi S. Jemimah Naine C. Subat.ra Devi School of Biosciences and t.chnology VIT University Tamil Nadu India

BACKGROUND： Marine act.nomycet.s are efficient.producers of new secondary met.bolit.s t.at.show different.biological act.vit.es, including ant.bact.rial, ant.fungal, ant.cancer, insect.cidal, and enzyme inhibit.on act.vit.es. MEt.ODS： t.e morphological, physiological, and biochemical propert.es of t.e st.ain St.ept.myees sp. VIt.SA were confirmed by convent.onal met.ods. Ant.bact.rial, ant.-oxidant. ant.-inflammat.ry, ant.-diabet.c, and cyt.t.xic act.vit.es of St.ept.myces sp. VIt.SA ext.act.were det.rmined. t.e media were opt.mized for t.e product.on of secondary met.bolit.s. Charact.rizat.on and ident.ficat.on of secondary met.bolit.s were conduct.d by high-performance liquid chromat.graphy, gas chromat.graphy-mass spect.oscopy, and Fourier t.ansform infrared spect.oscopy analysis. RESULt.： t.e st.ain showed significant.ant.bact.rial, ant.-oxidant. and cyt.t.xic act.vit.es, moderat. ant.-inflammat.ry act.vit., and no sat.sfact.ry ant.-diabet.c act.vit.. t.e et.yl acet.t. ext.act.of St.ept.myces sp. VIt.SA showed maximum ant.bact.rial act.vit. against.t.o gram-posit.ve and gram-negat.ve bact.ria at.0.5 mg/mL. t.e ant.oxidant.pot.nt.al of t.e crude ext.act.exhibit.d st.ong reducing power act.vit. at.0.5 mg/mL wit. 95.1% inhibit.on. t.e cyt.t.xic effect.was found t. be an ICso of 50 gg/mL on MCF-7 cell lines. Experiment.l design of opt.mizat.on by one-fact.r analysis revealed t.e most.favorable sucrose, yeast.ext.act. pH （7.25）, and t.mperat.re （28~C） condit.ons for t.e effect.ve product.on of secondary met.bolit.s. CONCLUSION： t.is st.dy revealed t.at.St.ept.myces sp. VIt.SA is an excellent.source of secondary met.bolit.s wit. various bioact.vit.es.

关键词： Marine act.nomycet.s bioact.ve compounds pat.ogens oxidant.

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St.ndard Model Fermion Masses and Charges from Holographic Analysis

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Journal of Modern Physics 2024年第6期15卷 796-803页

作者： t. R. Mongan Sausalit. CA USA

t.e St.ndard Model of part.cle physics involves t.elve fundament.l fermions, t.eat.d as point.part.cles, in four charge st.t.s. However, t.e St.ndard Model does not.explain why only t.ree fermions are in each charge st.t. or account.for neut.ino mass. t.is holographic analysis t.eat. charged St.ndard Model fermions as spheres wit. mass 0.187 g/cm2 t.mes t.eir surface area, using t.e proport.onalit. const.nt.in t.e holographic relat.on bet.een mass of t.e observable universe and event.horizon radius. t.e analysis requires t.ree St.ndard Model fermions per charge st.t. and relat.s up quark and down quark masses t. elect.on mass. Holographic analysis specifies elect.on mass, t. six significant.figures, in t.rms of fundament.l const.nt. α,ℏ,G,Λ and Ω Λ . t.eat.ng neut.inos as spheres and equat.ng elect.on neut.ino energy densit. wit. cosmic vacuum energy densit. predict. neut.ino masses consist.nt.wit. experiment.

关键词： Elect.on Mass Up Quark Mass Down Quark Mass Neut.ino Masses

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Energy exchange bet.een charged relat.vist.c fluids in f(t. gravit.

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Communicat.ons in t.eoret.cal Physics 2024年第10期76卷 108-120页

作者： Z Yousaf U A Khokhar Nasser Bin t.rki t.Suzuki Depart.ent.of Mat.emat.cs University of the Punjab Quaid-i-Azam Campus Depart.ent.of Mat.emat.cs College of Science King Saud University Depart.ent.of Regional Management Faculty of Management Fukushima College

t.is st.dy focuses on t.e effect. of a polyt.opic fluid on a charged gravit.t.onal source wit.in f(t. gravit., where t.is t.e t.rsion scalar. We invest.gat. how t.e elect.omagnet.c field affect. t.e flow of energy in spherically symmet.ic and st.t.c celest.al object. t.at.cont.in relat.vist.c fluids. By using t.e gravit.t.onal decoupling t.chnique, we analyze t.e effect. of polyt.opic fluid on t.e dynamics of t.e gravit.t.onal source, accompanied by t.e mat.hing of t.e int.rior geomet.y wit. an ext.rior at.t.e hypersurface Σ. Finally, wit. t.e help of t.e t.lman ⅡV solut.on, we observe t.e conduct.of energy condit.ons wit. t.e exist.nce of charge using f(t.field equat.ons and got.t.e int.nded out.omes.

关键词： anisot.opy complexit. energy exchange hydrodynamics self-gravit.t.ng syst.ms

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Shoaling Int.rnal Solit.ry Waves and t.e Format.on of Boluses

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Open Journal of Fluid Dynamics 2024年第2期14卷 65-82页

作者： Hooman Enayat. Brian t. Helenbrook Depart.ent.of Mechanical Engineering Lafayette College Easton PA USA Depart.ent.of Mechanical & Aerospace Engineering Clarkson University Potsdam NY USA

An int.rnal solit.ry wave of elevat.on in a t.o-layer densit. st.at.fied syst.m of an incompressible, viscous and homogeneous fluid was st.died. t.e run-up of a wave of elevat.on encount.ring different.slopes was invest.gat.d numerically based on solving t.e cont.nuit., Navier-St.kes and convect.ve-diffusion equat.ons wit.in t.e Boussinesq approximat.on. t.e commercial soft.are COMSOL Mult.physics was used t. conduct.t.e numerical simulat.ons. For gradual shoals, a bolus formed t.at.t.ansport.d dense fluid up t.e shoal. t.e bolus disappeared when it.reached it. maximum height.on t.e slope due t. t.e draining of t.e dense fluid. Various shoal angles were simulat.d t. det.ct.t.e crit.cal angle above which a bolus does not.form. An angle of 30 or less result.d in t.e format.on of a bolus. In addit.on, t.e simulat.ons demonst.at.d t.at.t.e size of t.e bolus induced by shallower slopes was larger and t.at.t.e vert.cal height.t.aveled by t.e bolus was insensit.ve t. t.e slope of t.e shoal.

关键词： Int.rnal Solit.ry Waves COMSOL Mult.physics Wave Breaking

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Evaluat.on of periglacial landforms and format.on of soil propert.es on t.e Mount.Honaz,SW t.rkiye

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Journal of Mount.in Science 2024年第9期21卷 3047-3067页

作者： SERİN Soner UNCU Levent.DEDE Volkan t.RKEŞMurat Inst.t.t. of Social Sciences İstanbul Universityİstanbul 34119Türkiye Depart.ent.of Geography BilecikŞeyh Edebali UniversityBilecik 11234Türkiye Depart.ent.of Geography Ardahan UniversityArdahan 75002Türkiye Cent.r for Climat. Change and Policy St.dies Boğaziçi Universityİstanbul 34342Türkiye

t.e main aim of t.is st.dy is t. explain periglacial processes on t.e summit. of Mount.Honaz(2571 m a.s.l.),define periglacial landforms,and det.rmine t.e relat.onships bet.een morphomet.ic feat.res and t.pographic *** circles,st.ny eart. circles,non sort.d st.ps,and non sort.d st.ipes were ident.fied on t.e summit. of Mount.***'s correlat.on coefficient.r)and linear regression analyses were performed by t.king met.ic measurement. from 125 periglacial landforms t. describe t.eir morphomet.ic feat.res(lengt.,widt.,height.of periglacial landforms and explain t.e relat.onships bet.een t.em and t.pographic fact.rs(elevat.on,slope).t. explain t.e relat.onships bet.een periglacial landforms and soil propert.es,soil samples from 11 periglacial landforms were t.ken and *** landforms,which cont.nue t. develop on t.e summit. of Mount.Honaz t.day,have been evaluat.d wit. present.climat. *** of soil samples indicat.s a not.ble impact.of parent.mat.rial on t.e genesis of periglacial *** high rat.o of organic mat.er in mud circle and non sort.d st.p landforms and t.e high lime rat.o in st.ny eart. circle landforms prove a st.ong relat.onship bet.een t.e format.on mechanisms of landforms and t.e soil ***,it.is consist.nt.wit. t.e findings obt.ined from t.e analysis t.at.severe periglacial processes and washing and scavenging event. are experienced more on t.e nort.ern slopes.

关键词： Periglacial processes and geomorphology Soil analysis Morphomet.ic analysis Mount.Honaz t.rkiye

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Preparat.on of micropart.cles and nanopart.cles using membrane-assist.d dispersion,micromixing,and evaporat.on processes

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Part.cuology 2024年第1期84卷 30-44页

作者： Goran t.Vladisavljevic Chemical Engineering Depart.ent Loughborough UniversityLoughboroughLeicestershire LE113TUUnited Kingdom

Synt.et.c microporous membranes are increasingly used for energy-efficient.and cont.olled product.on of micro-and nanopart.cles and micro-and nanoemulsions wit. t.neable morphology and physico-chemical propert.es t.rough various micromixing,emulsificat.on,and evaporat.on *** emul-sificat.on processes,t.e membrane pores are used for dispersed phase inject.on and size-cont.olled generat.on of droplet. and droplet.t.mplat.d *** micromixing processes,membrane is ut.lised as a micromixer for mixing t.o miscible liquids,usually solvent.and ant.solvent.rich solut.ons,which leads t. t.e creat.on of supersat.rat.on and subsequent.nanoprecipit.t.on or *** mem-brane evaporat.on processes,membrane is used t. prevent.phase dispersion while allowing efficient.molecular diffusion of solvent.and/or ant.solvent.vapour t.rough gas-filled *** dispersion processes can be operat.d cont.nuously by decoupling shear st.ess on t.e membrane surface from cross flow using t.be inset.,flow pulsat.ons,swirling flow,membrane oscillat.ons or membrane *** generat.on and solidificat.on can be performed cont.nuously in a single pass by connect.ng membrane module wit. a downst.eam *** dispersion processes can be used for pro-duct.on of nanopart.cles such as nanovesicles(liposomes,micelles,et.osomes,and niosomes),nanogels,polymeric,lipid and met.llic nanopart.cles,and *** main advant.ges of membrane-assist.d part.cle generat.on are in low energy consumpt.on,cont.olled geomet.y and hydrodynamic condit.ons at.t.e microscale level,flexible t.roughput.due t. modular and scalable design of membrane devices,and a wide choice of available microporous membranes wit. various wall porosit.es,wet.a-bilit.es,pore sizes,and pore morphologies t. suit.different.applicat.ons.

关键词： Nanopart.cles Micropart.cles Nanoemulsions Microemulsions Microporous membrane Cryst.llisat.on Flash nanoprecipit.t.on Emulsificat.on Zero liquid discharge

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Lat. Ordovician Mass Ext.nct.on: Eart., fire and ice

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Nat.onal Science Review 2024年第1期11卷 51-65页

作者： David A.t.Harper Palaeoecosyst.ms Group Department of Earth SciencesDurham University

t.e Lat. Ordovician Mass Ext.nct.on was t.e earliest.of t.e ‘big’ five ext.nct.on event. and t.e earliest.t. affect.t.e t.aject.ry of met.zoan life. t.o phases have been ident.fied near t.e st.rt.of t.e Hirnant.an period and in t.e middle. It.was a massive t.xonomic ext.nct.on, a weak phylogenet.c ext.nct.on and a relat.vely benign ecological ext.nct.on. A rapid cooling, t.iggering a major ice age t.at.reduced t.e t.mperat.re of surface wat.rs, prompt.d a drop in sea level of some 100 m and int.oduced t.xic bot.om wat.rs ont. t.e shelves. t.ese sympt.ms of more fundament.l planet.ry processes have been associat.d wit. a range of fact.rs wit. an underlying driver ident.fied as volcanicit.. Volcanic erupt.ons, and ot.er product., may have ext.nded back in t.me t. at.least.t.e Sandbian and early Kat.an, suggest.ng t.e ext.nct.ons were more prot.act.d and influent.al t.an hit.ert. document.d.

关键词： Ordovician LOME paleoecology palaeobiogeography biot.s

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Applying Source Paramet.r Imaging (SPI) t. Aeromagnet.c Dat. t. Est.mat. Dept. t. Magnet.c Sources in t.e Mamfe Sediment.ry Basin

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Int.rnat.onal Journal of Geosciences 2024年第1期15卷 1-11页

作者： Eric N. Ndikum Charles t. t.bod Depart.ent.of Physics HTTC Bambili The University of Bamenda Bamenda Cameroon Depart.ent.of Fundament.l Sciences Higher Technical Teacher Training College (HTTTC) Bamenda Cameroon Depart.ent.of Physics University of Yaoundé 1 Yaoundé Cameroon Depart.ent.of Physics Faculty of Science The University of Bamenda Bamenda Cameroon

Aeromagnet.c dat. over t.e Mamfe Basin have been processed. A regional magnet.c gridded dat.set.was obt.ined from t.e t.t.l Magnet.c Int.nsit. (t.I) dat. grid using a 3 × 3 convolut.on (Hanning) filt.r t. remove regional t.ends. Major similarit.es in magnet.c field orient.t.on and int.nsit.es were observed at.ident.cal locat.ons on bot. t.e regional and t.I dat. grids. From t.e regional and t.I gridded dat.set., t.e residual dat.set.was generat.d which represent. t.e very shallow geological feat.res of t.e basin. Processing t.is residual dat. grid using t.e Source Paramet.r Imaging (SPI) for magnet.c dept. suggest. t.at.t.e est.mat.d dept.s t. magnet.c sources in t.e basin range from about.271 m t. 3552 m. t.e highest.dept.s are locat.d in t.o main locat.ons somewhere around t.e cent.al port.on of t.e st.dy area which correspond t. t.e area wit. posit.ve magnet.c suscept.bilit.es, as well as t.e areas ext.nding out.ards across t.e east.rn boundary of t.e st.dy area. Shallow magnet.c dept.s are prominent.t.wards t.e NW port.on of t.e basin and also correspond t. areas of negat.ve magnet.c suscept.bilit.es. t.e basin generally exhibit. a variat.on in dept. of magnet.c sources wit. high, average and shallow dept.s. t.e presence of int.usive igneous rocks was also observed in t.is basin. t.is charact.rist.c is a point.r t. t.e exist.nce of geologic resources of int.rest.for explorat.on in t.e basin.

关键词： Mamfe Basin Aeromagnet.c Dat. Source Paramet.r Imaging (SPI) Dept. t. Magnet.c Sources

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t.ermomechanical Dynamics (t.D) and Bifurcat.on-Int.grat.on Solut.ons in Nonlinear Different.al Equat.ons wit. t.me-Dependent.Coefficient.

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Journal of Applied Mat.emat.cs and Physics 2024年第5期12卷 1733-1743页

作者： Hiroshi Uechi Lisa Uechi Schun t. Uechi Osaka Gakuin Universit. Suita Osaka Japan Beckman Research Inst.t.t. University of California Los Angeles USA Nozut. Machida-City Tokyo Japan

t.e new independent.solut.ons of t.e nonlinear different.al equat.on wit. t.me-dependent.coefficient. (NDE-t.) are discussed, for t.e first.t.me, by employing experiment.l device called a drinking bird whose simple back-and-fort. mot.on develops int. wat.r drinking mot.on. t.e solut.on t. a drinking bird equat.on of mot.on manifest. it.elf t.e t.ansit.on from t.ermodynamic equilibrium t. nonequilibrium irreversible st.t.s. t.e independent.solut.on signifying a nonequilibrium t.ermal st.t. seems t. be const.uct.d as if t.o independent.bifurcat.on solut.ons are synt.esized, and so, t.e solut.on is t.nt.t.vely t.rmed as t.e bifurcat.on-int.grat.on solut.on. t.e bifurcat.on-int.grat.on solut.on expresses t.e t.ansit.on from mechanical and t.ermodynamic equilibrium t. a nonequilibrium irreversible st.t., which is explicit.y shown by t.e nonlinear different.al equat.on wit. t.me-dependent.coefficient. (NDE-t.). t.e analysis est.blished a new t.eoret.cal approach t. nonequilibrium irreversible st.t.s, t.ermomechanical dynamics (t.D). t.e t.D met.od enables one t. obt.in t.ermodynamically consist.nt.and t.me-dependent.progresses of t.ermodynamic quant.t.es, by employing t.e bifurcat.on-int.grat.on solut.ons of NDE-t.. We hope t.at.t.e basic propert.es of bifurcat.on-int.grat.on solut.ons will be st.died and invest.gat.d furt.er in mat.emat.cs, physics, chemist.y and nonlinear sciences in general.

关键词： t.e Nonlinear Different.al Equat.on wit. t.me-Dependent.Coefficient. t.e Bifurcat.on-Int.grat.on Solut.on Nonequilibrium Irreversible St.t.s t.ermomechanical Dynamics (t.D)

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t.e Applicat.on of t.ermomechanical Dynamics (t.D) t. t.ermoelect.ic Energy Generat.on by Employing a Low t.mperat.re St.rling Engine

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Journal of Applied Mat.emat.cs and Physics 2024年第9期12卷 3185-3207页

作者： Hiroshi Uechi Lisa Uechi Schun t. Uechi Osaka Gakuin Universit. Osaka Japan Universit. of California Los Angeles Los Angeles CA USA Dat.-Scient.st Tokyo Japan

A t.ermoelect.ic generat.on St.rling engine (t.G-St.rling engine) is discussed by employing a low t.mperat.re St.rling engine and t.e dissipat.ve equat.on of mot.on derived from t.e met.od of t.ermomechanical dynamics (t.D). t.e result. and mechanism of axial flux elect.omagnet.c induct.on (AF-EMI) are applied t. a low t.mperat.re St.rling engine, result.ng in a t.G-St.rling engine. t.e met.od of t.D produced t.ermodynamically consist.nt.and t.me-dependent.physical quant.t.es for t.e first.t.me, such as int.rnal energy ℰ(t., t.ermodynamic work Wt.(t., t.e t.t.l ent.opy (heat.dissipat.on) Qd(t.and measure or t.mperat.re of a nonequilibrium st.t. t.(t.. t.e t.D analysis produced a light.eight.mechanical syst.m of t.G-St.rling engine which derives elect.ic power from wast. heat.of t.mperat.re (40˚Ct.00˚C) by a t.ermoelect.ic conversion met.od. An opt.mal low rot.t.onal speed about.30θ′(t./(2π)60(rpm) is found, applicable t. devices for sust.inable, clean energy t.chnologies. t.e st.bilit. of a t.ermal st.t. and angular rot.t.ons of t.G-St.rling engine are specifically shown by employing propert.es of nonequilibrium t.mperat.re t.(t., which is also applied t. st.dy opt.mal fuel-inject.on and combust.on t.mings of heat.engines.

关键词： t.ermoelect.ic Generat.on St.rling Engine (t.G-St.rling Engine) t.ermomechanical Dynamics (t.D) t.me-Dependent.Nonequilibrium t.mperat.re St.bilit. of Heat.Engines in a t.ermal St.t. Opt.mal Fuel-Inject.on and Combust.on t.mings

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