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Developing a Novel Single-Marker-Based Method for the Quantitative Evaluation of the Multiple Active Components in Corydalis yanhusuo W. t. wang

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World Journal of traditional Chinese Medicine 2023年第1期9卷 43-52页

作者： Xin-Rong Yang Shuang Jiang Chun-Li Gan Jing Huang Fan-Shu Wei Zheng-Yang wang He-Song Peng Jing Yang Chun-Juan Yang Department of Pharmaceutical Analysis and Analytical Chemistry College of PharmacyHarbin Medical UniversityHarbinChina Department of Medicinal Chemistry and Natural Medicine Chemistry College of PharmacyHarbin Medical UniversityHarbinChina Analytical Department Johnson and Johnson199 Grandview RoadSkillmanNJUSA

Objective: this study was designed to develop a method for detecting differences in the chemical composition of Corydalis yanhusuo W. t. wang using high-performance liquid chromatography with a diode array detector technology. Materials and Methods: We established a novel quantitative evaluation method for identifying multiple components in natural extracts using a single-marker method quantitative analysis of multi-components by single marker(QAMS). this method was then validated using eight alkaloid phytochemical markers designed to evaluate C. yanhusuo quality. Results: Our evaluations revealed good linearity(R^(2) ≥ 0.9991) within the range of tested concentrations for all eight alkaloids, with recovery ranging from 95.5% to 101.5%. the evaluations also returned stability results that fell within the acceptable range. Cluster analysis and Heatmap analyses were applied to classify and evaluate alkaloids across 21 different production areas. these results revealed a significant difference in the component profiles between samples from different origins. Conclusions: thus, these data suggest that in the absence of a material reference, QAMS may help facilitate the stable production of C. yanhusuo. In addition, our data suggest that this method may have value as a promising alternative to common quality evaluations for controlling C. yanhusuo composition.

关键词： Corydalis yanhusuo W.t.wang high-performance liquid chromatography with a diode array detector QAMS quality evaluation

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MRI评估深髓静脉相关脑血管病的研究进展

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中国介入影像与治疗学 2024年第6期21卷 378-381页

作者：王天然刘冲保定市第一中心医院医学影像科河北保定071000

脑血管病指多种因素致脑血管损害所引起脑组织短暂性或永久性功能障碍性疾病。深髓静脉为颅内重要引流静脉,影响深部脑实质静脉回流,且对于评估脑血管病严重程度及指导治疗策略等具有重要作用。本文围绕MRI评估深髓静脉相关脑血管病的... 详细信息

脑血管病指多种因素致脑血管损害所引起脑组织短暂性或永久性功能障碍性疾病。深髓静脉为颅内重要引流静脉,影响深部脑实质静脉回流,且对于评估脑血管病严重程度及指导治疗策略等具有重要作用。本文围绕MRI评估深髓静脉相关脑血管病的研究进展进行综述。

关键词：脑静脉磁共振成像

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Corydalis yanhusuo W. t. wang

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Journal of Pharmaceutical Analysis 2013年第6期 386-386页

作者： wang XM Xi’an Jiaotong University

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Energy principle of ferroelectric ceramics and single domain mechanical model

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Acta Mechanica Sinica 2007年第5期23卷 531-543页

作者： t.C.wang LNM Institute of MechanicsChinese Academy of SciencesBeijing 100080China

Many physical experiments have shown that the domain switching in a ferroelectric material is a complicated evolution process of the domain wall with the variation of stress and electric field. According to this mechanism, the volume fraction of the domain switching is introduced in the constitutive law of ferroelectric ceramic and used to study the nonlinear constitutive behavior of ferroelectric body in this paper. the principle of stationary total energy is put forward in which the basic unknown quantities are the displacement ui, electric displacement Di and volume fraction pI of the domain switching for the variant I. Mechanical field equation and a new domain switching criterion are obtained from the principle of stationary total energy. the domain switching criterion proposed in this paper is an expansion and development of the energy criterion. On the basis of the domain switching criterion, a set of linear algebraic equations for the volume fraction PI of domain switching is obtained, in which the coefficients of the linear algebraic equations only contain the unknown strain and electric fields. then a single domain mechanical model is proposed in this paper. the poled ferroelectric specimen is considered as a transversely isotropic single domain. By using the partial experimental results, the hardening relation between the driving force of domain switching and the volume fraction of domain switching can be calibrated. then the electromechanical response can be calculated on the basis of the calibrated hardening relation. the results involve the electric butterfly shaped curves of axial strain versus axial electric field, the hysteresis loops of electric displacement versus electric filed and the evo- lution process of the domain switching in the ferroelectric specimens under uniaxial coupled stress and electric field loading. the present theoretic prediction agrees reasonably with the experimental results given by Lynch.

关键词： Ferroelectric ceramic Domain switching the volume fraction of domain switching Single domain mechanical model

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Designing ultrastrong maraging stainless steels with improved uniform plastic strain via controlled precipitation of coherent nanoparticles

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Journal of Materials Science & technology 2021年第34期93卷 60-70页

作者： Z.H.wang B.Niu Q.wang C.Dong J.C.Jie t.M.wang t.G.Nieh Key Laboratory of Materials Modification by Laser Ion and Electron Beams(Ministry of Education)School of Materials Science and EngineeringDalian University of TechnologyDalian116024China Department of Materials Science and Engineering The University of TennesseeKnoxville37996TennesseeUSA

the development of ultrastrong maraging stainless steels(MSSs)is always in high ***,traditional high-strength MSSs generally exhibit early plastic instability with a low uniform strain since the precipitated nanoparticles are non-coherent with the body-centered-cubic(BCC)lath martensitic ***,we design a novel ultrahigh strength MSS(Fe-5.30 Cr-13.47 Ni-3.10 Al-1.22 Mo-0.50 W-0.23 Nb-0.03 C-0.005 B,wt.%)using a cluster formula approach.A fabulous microstructure consisting of a uniform distribution of high-density coherent B2-Ni Al nanoprecipitates(3-5 nm)in BCC martensitic matrix was successfully *** alloy has not only an exceedingly high ultimate tensile strength of 2.0 GPa,but also a decent uniform elongation of 4.2%-5.1%,which is almost triple of the value observed in existing *** present an in-depth discussion on the origins of ultrahigh strength and uniform plastic strain in the new alloy to validate our design strategy and further offer a new pathway to exploit highperformance MSSs.

关键词： Maraging stainless steel Ultrahigh strength Coherent precipitation Strengthening mechanisms Uniform deformation

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Amplitude analysis of the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

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Chinese Physics C 2024年第8期48卷 6-33页

作者： M.Ablikim M.N.Achasov P.Adlarson O.Afedulidis X.C.Ai R.Aliberti A.Amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-R.Bao V.Batozskaya K.Begzsuren N.Berger M.Berlowski M.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen M.L.Chen S.J.Chen S.L.Chen S.M.Chen t.Chen X.R.Chen X.t.Chen Y.B.Chen Y.Q.Chen Z.J.Chen Z.Y.Chen S.K.Choi X.Chu G.Cibinetto F.Cossio J.J.Cui H.L.Dai J.P.Dai A.Dbeyssi R.E.de Boer D.Dedovich C.Q.Deng Z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori B.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng Y.t.Feng K.Fischer M.Fritsch C.D.Fu J.L.Fu Y.W.Fu H.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia P.t.Ge Z.W.Ge C.Geng E.M.Gersabeck B.Ding X.X.Ding Y.Ding Y.Ding J.Dong L.Y.Dong M.Y.Dong X.Dong M.C.Du S.X.Du Z.H.Duan P.Egorov Y.H.Fan J.Fang JA.Gilman K.Goetzen L.Gong W.X.Gong W.Gradl S.Gramigna M.Greco M.H.Gu Y.t.Gu C.Y.Guan Z.L.Guan A.Q.Guo L.B.Guo M.J.Guo R.P.Guo Y.P.Guo A.Guskov J.Gutierrez K.L.Han t.t.Han X.Q.Hao F.A.Harris K.K.He K.L.He F.H.Heinsius C.H.Heinz Y.K.Heng C.Herold t.Holtmann P.C.Hong G.Y.Hou X.t.Hou Y.R.Hou Z.L.Hou B.Y.Hu H.M.Hu J.F.Hu t.Hu Y.Hu G.S.Huang K.X.Huang L.Q.Huang X.t.Huang Y.P.Huang t.Hussain F.H\"olzken N.H\"usken N.in der Wiesche M.Irshad J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.P.Ji W.Ji X.B.Ji X.L.Ji Y.Y.Ji X.Q.Jia Z.K.Jia D.Jiang H.B.Jiang P.C.Jiang S.S.Jiang t.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.K.Jiao Z.Jiao S.Jin Y.Jin M.Q.Jing X.M.Jing t.Johansson S.Kabana N.Kalantar-Nayestanaki X.L.Kang X.S.Kang M.Kavatsyuk B.C.Ke V.Khachatryan A.Khoukaz R.Kiuchi O.B.Kolcu B.Kopf M.Kuessner X.Kui A.Kupsc W.K\"uhn J.J.Lane P.Larin L.Lavezzi t.t.Lei Z.H.Lei H.Leithoff M.Lellmann t.Lenz C.Li C.Li C.H.Li Cheng Li D.M.Li F.Li G.Li H.Li H.B.Li H.J.Li H.N.Li Hui Li J.R.Li J.S.Li K.Li L.J.Li L.K.Li Lei Li M.H.Li P.R.Li Q.M.Li Q.X.Li R.Li S.X.Li t.Li W.D.Li W.G.Li X.Li X.H.Li X.L.Li X.Y.Li Y Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Bochum Ruhr-University D-44780 BochumGermany Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and technology Beijing 100190China China University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COMSAtS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of Science and technology Luoyang 471003China Henan University of technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of Modern Physics Lanzhou 730000China Institute of Physics and technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector,a joint amplitude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).the fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained amplitude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,*** branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,*** amplitude analysis provides an important model for the binning strategy in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CKM angleγ(ϕ_(3))via the B^(−)→DK^(−)decay.

关键词： BESIII D^(0)meson decays amplitude analysis CP-even fraction

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Variational principle for a special Cosserat rod

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Applied Mathematics and Mechanics(English Edition) 2009年第9期30卷 1169-1176页

作者：刘东生 Charles H-t wang Applied Mathematics Department Nanjing University of Science and Technology School of Engineering and Physical Sciences University of Aberdeen

In this paper, we describe the nonlinear models of a rod in three-dimensional space based on the Cosserat theory. Using the pseudo-rigid body method and variational principle, we obtain the motion equations of a Cosse... 详细信息

关键词： rod variational principle Cosserat theory

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DeepSun:machine-learning-as-a-service for solar flare prediction

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Research in Astronomy and Astrophysics 2021年第7期21卷 51-61页

作者： Yasser Abduallah Jason t.L.wang Yang Nie Chang Liu Haimin wang Institute for Space Weather Sciences New Jersey Institute of TechnologyUniversity HeightsNewarkNJ 07102-1982USA Department of Computer Science New Jersey Institute of TechnologyUniversity HeightsNewarkNJ 07102-1982USA Big Bear Solar Observatory New Jersey Institute of Technology40386 North Shore LaneBig Bear CityCA 92314-9672USA Center for Solar-terrestrial Research New Jersey Institute of TechnologyUniversity HeightsNewarkNJ 07102-1982USA

Solar flare prediction plays an important role in understanding and forecasting space *** main goal of the Helioseismic and Magnetic Imager(HMI), one of the instruments on NASA's Solar Dynamics Observatory, is to study the origin of solar variability and characterize the Sun's magnetic *** provides continuous full-disk observations of the solar vector magnetic field with high cadence data that lead to reliable predictive capability;yet, solar flare prediction effort utilizing these data is still limited. In this paper, we present a machine-learning-as-a-service(MLaa S) framework, called Deep Sun,for predicting solar flares on the web based on HMI's data products. Specifically, we construct training data by utilizing the physical parameters provided by the Space-weather HMI Active Region Patch(SHARP)and categorize solar flares into four classes, namely B, C, M and X, according to the X-ray flare catalogs available at the National Centers for Environmental Information(NCEI). thus, the solar flare prediction problem at hand is essentially a multi-class(i.e., four-class) classification problem. the Deep Sun system employs several machine learning algorithms to tackle this multi-class prediction problem and provides an application programming interface(API) for remote programming users. to our knowledge, Deep Sun is the first MLaa S tool capable of predicting solar flares through the internet.

关键词： Sun:flares Sun:activity methods:data analysis

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Using Folding Ensemble and Stem Probability Maximization Methods to Predict RNA H-type Pseudoknots

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tsinghua Science and technology 2012年第6期17卷 691-700页

作者： Junilda Spirollari Shawn Xiong wang Jason t.L. wang Bioinformatics Program Department of Computer Science New Jersey Institute of Technology University Heights Department of Computer Science California State University

We present in this paper an ab initio method, named KnotFold, for RNA H-type pseudoknot prediction. Our method employs an ensemble of RNA folding tools and a filtering heuristic to generate a set of pseudoknot-free stems, and then predicts pseudoknots by utilizing a search technique with a pseudo-probability scoring scheme. Experimental results show that KnotFold achieves higher sensitivity than existing methods. the KnotFold package with documentation is freely available at http：//***/KnotFold.

关键词： RNA structure pseudoknots tool ensemble

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Novel insight into dry sliding behavior of Cu-Pb-Sn in-situ composite with secondary phase in different morphology

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Journal of Materials Science & technology 2020年第5期40卷 158-167页

作者： B.W.Dong S.H.wang Z.Z.Dong J.C.Jie t.M.wang t.J.Li School of Material Science and Engineering Dalian University of TechnologyDalian 116024China

the Cu-24 Pb-x Sn(wt%)(x=0,2,4,6)alloys with Pb-rich second-phase particles(SPPs)in different shapes show obviously differently mechanical and self-lubricating *** influence of the SPPs’shape difference on the alloys’mechanical and self-lubricating properties was ***-24 Pb alloy with continuously netty SPPs shows much more intensive stick-slip phenomenon during dry sliding than the other three alloys with independently rodlike *** is mainly due to insufficient lubrication resulted by the netty SPPs’splitting *** the SPPs transforming from netty to rodlike shape under the addition of Sn,the stick-slip phenomenon was notably weakened,which was proven to be related to the higher self-lubricating property of alloys with rodlike ***,the simultaneous increase of ductility and tensile strength was observed in the Cu-24 Pb-x Sn alloys with increasing Sn content,which is because the netty SPPs’splitting behavior will be weakened with them replaced by the rodlike SPPs.

关键词： Second-phase particles Netty shape Rodlike shape Stick-slip Mechanical property Self-lubricating property

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