BACKGROUND Aseptic acetabular loosening can result from various factors that can be categorized into groups:patient-related,surgeon-related and *** present a case of a 63-year-old patient who at first underwent a tota...
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BACKGROUND Aseptic acetabular loosening can result from various factors that can be categorized into groups:patient-related,surgeon-related and *** present a case of a 63-year-old patient who at first underwent a total hip arthro-plasty(THA)using a metal-on-metal bearing due to hip ***-up visits revealed no complications after the *** years after the THA,acetabular component loosening occurred due to subsequent trauma of the opposite hip,necessitating a revision THA using a ceramic-on-ceramic *** SUMMARY We aim to illustrate a rare case where the primary reason for undergoing THA revision was not only incomplete bone graft incorporation but also improper limb load *** the revision arthroplasty,a 9-year follow-up visit revealed improvements in all evaluation measures on questionnaire compared to the state before surgery:Harris Hip Score(before surgery:15;after surgery:95),Western Ontario and McMaster Universities Arthritis Index(before surgery:96;after surgery:0),and Visual Analogue Scale(before surgery:10;after surgery:1).CONCLUSION Opposite-hip trauma caused a weight transfer to the limb after a THA *** process led to a stress shielding effect,resulting in acetabular component loosening.
Production of morphologically and physiologically variable seeds is an important strategy that helps plants to survive in unpredictable natural ***,the model plant Arabidopsis thaliana and most agronomically essential...
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Production of morphologically and physiologically variable seeds is an important strategy that helps plants to survive in unpredictable natural ***,the model plant Arabidopsis thaliana and most agronomically essential crops produce visually homogenous *** automated phenotype analysis,we observed that small seeds in Arabidopsis tend to have higher primary and secondary dormancy levels than large *** analysis revealed distinct gene expression profiles between large and small *** seeds have higher expression of translation-related genes implicated in germination *** contrast,small seeds have elevated expression of many positive regulators of dormancy,including a key regulator of this process,the DOG1 *** in DOG1 expression are associated with differential production of its alternative cleavage and polyadenylation isoforms;in small seeds,the proximal poly(A)site is selected,resulting in a short mRNA ***,single-seed RNA sequencing analysis demonstrated that large seeds resemble DOG1 knockout mutant ***,on the single-seed level,expression of genes affected by seed size is correlated with expression of genes that position seeds on the path toward *** results demonstrate an unexpected link between seed size and dormancy phenotypes in a species that produces highly homogenous seed pools,suggesting that the correlation between seed morphology and physiology is more widespread than initially assumed.
In plants,sugars are the key source of energy and metabolic building *** systemic transport of sugars is essential for plant growth and *** evolved intricate molecular networks to effectively distribute *** dynamic di...
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In plants,sugars are the key source of energy and metabolic building *** systemic transport of sugars is essential for plant growth and *** evolved intricate molecular networks to effectively distribute *** dynamic distribution of these osmotically active compounds is a handy tool for regulating cell turgor pressure,an instructive force in developmental *** this study,we have investigated the molecular mechanism behind the dual role of the receptor-like kinase *** functionally characterized a long non-coding RNA,CARMA,as a negative regulator of *** CARMA specifically fine-tunes CANAR expression in the phloem,the route of sugar *** genetic,molecular,microscopy,and biophysical data suggest that the CARMA–CANAR module controls the shoot-to-root phloem transport of sugars,allows cells to flexibly adapt to the external osmolality by appropriate water uptake,and thus adjust the size of vascular cell types during organ growth and *** study identifies a nexus of plant vascular tissue formation with cell internal pressure monitoring,revealing a novel functional aspect of long non-coding RNAs in developmental biology.
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