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Risk factors and outcomes of peptic ulcer bleed in a Pakistani population:A single-center observational study

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World Journal of Gastrointestinal Pharmacology and Therapeutics 2024年第3期15卷 1-9页

作者： Nazish Butt Muhammad Tayyab Usmani Nimrah Mehak saba Mughal Fakhar Ali Qazi-Arisar Ghulam Mohiuddin Gulzar Khan Department of Gastroenterology Jinnah Postgraduate Medical CentreKarachi 75505SindhPakistan National Institute of Liver&GI Diseases Dow University of Health SciencesKarachi 75330SindhPakistan School of Public Health Dow University of Health SciencesKarachi 75330SindhPakistan

BACKGROUND Peptic ulcer disease(PUD)remains a significant healthcare burden,contributing to morbidity and mortality *** advancements in therapies,its prevalence persists,particularly in regions with widespread nonsteroidal antiinflammatory drugs(NSAIDs)use and Helicobacter pylori *** To comprehensively analyse the risk factors and outcomes of PUD-related upper gastrointestinal(GI)bleeding in Pakistani *** This retrospective cohort study included 142 patients with peptic ulcer bleeding who underwent upper GI endoscopy from January to December *** on demographics,symptoms,length of stay,mortality,re-bleed,and Forrest classification was *** The mean age of patients was 53 years,and the majority was men(68.3%).Hematemesis(82.4%)and epigastric pain(75.4%)were the most common presenting *** patients(73.2%)were discharged within five *** mortality rates at one week and one month were 10.6%and 14.8%,***-bleed within 24 h and seven days occurred in 14.1%and 18.3%of patients,*** ulcers were Forrest class(FC)Ⅲ(72.5%).Antiplatelet use was associated with higher mortality at 7 and 30 d,while alternative medications were linked to higher 24-hour re-bleed *** use was associated with more FCⅢ***-bleed at 24 h and 7 d was strongly associated with one-week or one-month *** Antiplatelet use and rebleeding increase the risk of early mortality in PUD-related upper GI bleeding,while alternative medicines are associated with early rebleeding.

关键词： Non variceal bleed Mortality Re-bleed Forrest classification Antiplatelets Alternative medicines

Particle shape consideration in numerical simulation of assemblies of irregularly shaped particles

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Particuology 2011年第4期9卷 387-397页

作者： saba Abedi Ali Asghar Mirghasemi School of Civil Engineering College of Engineering University of Tehran

The mechanical behavior of granular materials depends much on the shape of the constituent particles. Therefore appropriate modeling of particle, or grain, shape is quite important. This study employed the method of direct modeling of grain shape （Matsushima ＆ Saomto, 2002）, in which, the real shape of a grain is modeled by combining arbitrary number of overlapping circular elements which are connected to each other in a rigid way. Then, accordingly, a discrete-element program is used to simulate the assembly of grains. In order to measure the effects of grain shape on mechanical properties of assembly of grains, three types of grains-high angular grains, medium angular grains and round grains are considered where several biaxial tests are conducted on assemblies with different grain types, The results show that the angularity of grains greatly affects the behavior of granular soil.

关键词： Discrete element method Granular soil Angularity Confining pressure

Trustworthy Explainable Recommendation Framework for Relevancy

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Computers, Materials & Continua 2022年第12期73卷 5887-5909页

作者： saba Sana Mohammad Shoaib Department of Computer Science University of Engineering and TechnologyLahore54000Pakistan

Explainable recommendation systems deal with the problem of‘Why’.Besides providing the user with the recommendation,it is also explained why such an object is being *** helps to improve trustworthiness,effectiveness,efficiency,persuasiveness,and user satisfaction towards the *** recommend the relevant information with an explanation to the user is *** systems provide the top-k recommendation options to the user based on ratings and reviews about the required object but unable to explain the matched-attribute-based recommendation to the user.A framework is proposed to fetch the most specific information that matches the user requirements based on Formal Concept Analysis(FCA).The ranking quality of the recommendation list for the proposed system is evaluated quantitatively with Normalized Discounted Cumulative Gain(NDCG)@k,which is better than the existing *** is provided qualitatively by considering trustworthiness criterion i.e.,among the seven explainability evaluation criteria,and its metric satisfies the results of proposed *** framework can be enhanced to accommodate for more effectiveness and trustworthiness.

关键词： Explainable recommendation data analysis formal concept analysis(FCA)approach

On Graded Betti Numbers of a Class of Graphs

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Algebra Colloquium 2018年第2期25卷 335-348页

作者： saba Yasmeen Tongsuo Wu Department of Mathematics Shanghai Jiaotong University Shanghai 200240 China

In this paper, Betti numbers are evaluated for several classes of graphs whose complements are bipartite graphs. Relations are established for the general case, and counting formulae are given in several particular ca... 详细信息

关键词： graded Betti numbers disjoint union of graphs bipartite graphs

Profiling Casualty Severity Levels of Road Accident Using Weighted Majority Voting

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Computers, Materials & Continua 2022年第6期71卷 4609-4626页

作者： saba Awan Zahid Mehmood Hassan Nazeer Chaudhry Usman Tariq Amjad Rehman Tanzila saba Muhammad Rashid Department of Software Engineering University of Engineering and TechnologyTaxila47050Pakistan Department of Computer Engineering University of Engineering and TechnologyTaxila47050Pakistan Department of Electronics Information and BioengineeringPolitecnico di MilanoMilano20122Italy College of Computer Engineering and Sciences Prince Sattam bin Abdulaziz UniversityAl-Kharj11942Saudi Arabia College of Computer and Information Sciences Prince Sultan UniversityRiyadhSaudi Arabia Department of Computer Engineering Umm Al-Qura UniversityMakkah21421Saudi Arabia

To determine the individual circumstances that account for a road traffic accident,it is crucial to consider the unplanned connections amongst various factors related to a crash that results in high casualty *** of the road accident data concentrated mainly on categorizing accidents into different types using individually built classification methods which limit the prediction accuracy and fitness of the *** this article,we proposed a multi-model hybrid framework of the weighted majority voting(WMV)scheme with parallel structure,which is designed by integrating individually implemented multinomial logistic regression(MLR)and multilayer perceptron(MLP)classifiers using three different accident datasets i.e.,IRTAD,NCDB,and *** proposed WMV hybrid scheme overtook individual classifiers in terms of modern evaluation measures like ROC,RMSE,Kappa rate,classification accuracy,and performs better than state-of-theart approaches for the prediction of casualty severity ***,the proposed WMV hybrid scheme adds up to accident severity analysis through knowledge representation by revealing the role of different accident-related factors which expand the risk of casualty in a road *** aspects related to casualty severity recognized by the proposed WMV hybrid approach can surely support the traffic enforcement agencies to develop better road safety plans and ultimately save lives.

关键词： Prediction hybrid framework severity class casualty

Effect of CuO Doping on the Electrical Behavior of ZrO2

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Chinese Journal of Chemistry 2007年第8期25卷 1112-1115页

作者： saba Beg SARITA POOJA Varshney Department of Chemistry Aligarh Muslim University Aligarh 202002 India

Electrical conductivity has been measured at different temperatures for ZrO2 doped with various molar ratios of CuO. The conductivity increases due to migration of vacancies, created by doping. The conductivity was found to increase with increase in temperature till 220℃ and thereafter decrease due to collapse of the fluorite framework. A second rise in conductivity around 500 ℃ was observed due to phase transition of ZrO2. X-ray powder diffraction, DTA and IR studies were carried out for confirming doping effect and phase transition in ZrO2.

关键词： oxide doping effect electrical conductivity XRD

Enhancing pharmaceutical potential and oral bioavailability of Allium cepa nanosuspension in male albino rats using response surface methodology

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Asian Pacific Journal of Tropical Biomedicine 2022年第1期12卷 26-38页

作者： Fatiqa Zafar Nazish Jahan Shaukat Ali saba Jamil Riaz Hussain saba Aslam Department of Chemistry University of SahiwalSahiwalPakistan Department of Chemistry University of AgricultureFaisalabadPakistan Department of Chemistry University of OkaraOkaraPakistan Govt.Graduate College for Women Sargodha RoadFaisalabadPakistan

Objective:To enhance the pharmaceutical potential and oral bioavailability of quercetin contents of Allium cepa peel extract by novel nanosuspension ***:Nanoprecipitation approach was successfully used for the formulation of *** obtain pharmaceutical-grade nanosuspension with minimum particle size and polydispersity index,sodium lauryl sulphate was selected as a *** formulation parameters were statistically optimized by the response surface methodology *** optimized nanosuspension was subjected to stability and in vitro dissolution testing and characterized by scanning electron microscopy,atomic force microscopy,Fourier transform infrared spectroscopy,and zeta *** evaluate the preeminence of nanosuspension over coarse suspension,comparative bioavailability studies were carried out in male albino *** pharmaceutical potential of developed nanosuspension was evaluated by antioxidant,antimicrobial,and toxicity ***:The optimized nanosuspension showed an average particle size of 275.5 nm with a polydispersity index and zeta potential value of 0.415 and−48.8 mV,*** force microscopy revealed that the average particle size of nanosuspension was below 100 *** formulated nanosuspension showed better stability under refrigerated *** showed an improved dissolution rate and a 2.14-fold greater plasma concentration of quercetin than coarse ***,the formulated nanosuspension exhibited enhanced antioxidant and antimicrobial potential and was ***:Optimization of nanosuspension effectively improves the pharmaceutical potential and oral bioavailability of Allium cepa extract.

关键词： Allium cepa Nanoprecipitation Pharmaceutical potential Particle size Polydispersity index Stability Toxicity Quercetin

Determination of physical properties for the mixtures of [BMIM]Cl with different organic solvents

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Chinese Journal of Chemical Engineering 2015年第5期23卷 804-811页

作者： Hina saba Xinjun Zhu Ye Chen Yumei Zhang State Key Laboratory for Modification of Chemical Fibers and Polymer Materials Donghua University Department of Material and Engineering Luoyang Institute of Science and Technology

Physical properties including refractive index, density, viscosity and conductivity for binary mixtures of l-butyl- 3-methyl imidazolium chloride （[BMIM]CI） and different organic solvents at 298.15 K have been investigated. Ex- cess molar volumes have been calculated and obtained data has been fitted by the Redlich-Kister equation. The density and refractive index were found to increase with increasing concentration of [BMIM]CI, however, excep- tions do exist as in the case of dimethyl sulfoxide （DMSO）/[BMIM]CI. For DMSO/[BMIM]CI, the density decreases with increasing concentration. The addition of different organic solvents was able to disrupt the interactions within mixtures, leading to free mobility of ions. The free mobility of ions has been found to enhance conductivity and decrease viscosity to varying extents in all mixtures studied. It has been observed that solubility parameters, dielectric constants and composition of the solvents used play a vital role in determining the resultant properties. The data obtained will play an important role in understanding the effect of the addition of organic solvents in ILs to enhance their applicability.

关键词： Ionic liquid Viscosity Conductivity Refractive index Density Binary mixtures Organic solvents

Assessment of Cu(Ⅱ) removal from an aqueous solution by raw Gundelia tournefortii as a new low-cost biosorbent: Experiments and modelling

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Chinese Journal of Chemical Engineering 2019年第8期27卷 1945-1955页

作者： saba Golshan Shandi Faramarz Doulati Ardejani Fereydoun Sharifi School of Mining College of EngineeringUniversity of TehranTehranIran Faculty of Mining Petroleum and GeophysicsShahrood University of TechnologyShahroodIran

Lignocellulosic materials can be used as biosorbent for refinement of the wastewaters when they are available in large quantities. Many studies were conducted to uptake Cu(Ⅱ) ion from aqueous *** this paper, the biosorption efficiency of Cu(Ⅱ) ions from a synthetic aqueous solution was investigated using Gundelia tournefortii(GT), without any pre-treatment. Fourier transform infrared spectroscopy,scanning electron microscopy and determining the point of zero charge were employed to characterise the biosorbent. Batch experiments were performed to study the influence of p H, biosorbent dosage, contact time, temperature and initial Cu(Ⅱ) concentration on Cu(Ⅱ) removal. The biosorption isotherms were investigated using the Langmuir, Freundlich, Temkin and D-R isotherm models. The findings show that the biosorption isotherm was better fitted by the Langmuir equation and the maximum adsorption capacity of GT was found to be 38.7597 mg·g^-1. The kinetics data were analysed by pseudo-first order,pseudo-second order, and intra-particle diffusion equations. The results indicate that the pseudosecond-order model was found to explain the adsorption kinetics most effectively. The values of thermodynamic parameters including Gibbs free energy(△G°), enthalpy(△H°), and entropy(△S°) demonstrate that the biosorption process was exothermic and spontaneous. The multiple nonlinear regression(MnLR)and artificial neural network(ANN) analyses were applied for the prediction of biosorption capacity. A relationship between the predicted and observed data was obtained and the results show that the Mn LR and ANN models provided successful predictions.

关键词： Adsorption Batch experiment Kinetics Isotherms Thermodynamic Multiple nonlinear regression Artificial neural network