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A Novel Parallel Computing Confidentiality Scheme Based on Hindmarsh-Rose Model

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Computers, Materials & Continua 2023年第8期76卷 1325-1341页

作者： Jawad Ahmad Mimonah Al Qathrady Mohammed SAlshehri Yazeed Yasin Ghadi Mujeeb Ur Rehman syed aziz shah School of Computing Engineering and the Built EnvironmentEdinburgh Napier UniversityEdinburghEH105DTUK Department of Information Systems College of Computer Science and Information SystemsNajran UniversityNajran61441Saudi Arabia Department of Computer Science College of Computer Science and Information SystemsNajran UniversityNajran61441Saudi Arabia Department of Computer Science Al Ain UniversityAbu Dhabi112612United Arab Emirates School of Science Technology and HealthYork St John UniversityYorkYO317EXUK Research Centre for Intelligent Healthcare Coventry UniversityCoventryCV15FBUK

Due to the inherent insecure nature of the Internet,it is crucial to ensure the secure transmission of image data over this ***,given the limitations of computers,it becomes evenmore important to employ efficient and fast image encryption *** 1D chaotic maps offer a practical approach to real-time image encryption,their limited flexibility and increased vulnerability restrict their practical *** this research,we have utilized a 3DHindmarsh-Rosemodel to construct a secure *** randomness of the chaotic map is assessed through standard *** proposed system enhances security by incorporating an increased number of system parameters and a wide range of chaotic parameters,as well as ensuring a uniformdistribution of chaotic signals across the entire value ***,a fast image encryption technique utilizing the new chaotic system is *** novelty of the approach is confirmed through time complexity *** further strengthen the resistance against cryptanalysis attacks and differential attacks,the SHA-256 algorithm is employed for secure key *** results through a number of parameters demonstrate the strong cryptographic performance of the proposed image encryption approach,highlighting its exceptional suitability for secure ***,the security of the proposed scheme has been compared with stateof-the-art image encryption schemes,and all comparison metrics indicate the superior performance of the proposed scheme.

关键词： Hindmarsh-rose model image encryption SHA-256 parallel computing

Enhancing Mild Cognitive Impairment Detection through Efficient Magnetic Resonance Image Analysis

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Computers, Materials & Continua 2024年第8期80卷 2081-2098页

作者： Atif Mehmood Zhonglong Zheng Rizwan Khan Ahmad Al Smadi Farah shahid shahid Iqbal Mutasem K.Alsmadi Yazeed Yasin Ghadi syed aziz shah Mostafa M.Ibrahim Department of Computer Science and Technology Zhejiang Normal UniversityJinhua321002China Zhejiang Institute of Photoelectronics&Zhejiang Institute for Advanced Light Source Zhejiang Normal UniversityJinhua321004China Department of Data Science and Artificial Intelligence Zarqa UniversityZarqa13100Jordan School of Chemical and Environmental Engineering College of ChemistryChemical Engineering andMaterials ScienceSoochow UniversitySuzhou215123China Department of Management Information Systems College of Applied Studies and Community ServiceImam Abdulrahman Bin Faisal UniversityDammam32244Saudi Arabia Department of Computer Science Al Ain UniversityAbu Dhabi999041United Arab Emirates Department of Electrical Engineering Faculty of EngineeringMinia UniversityMinia61519Egypt Healthcare Technology and Innovation Theme Faculty Research Centre for Intelligent HealthcareCoventry UniversityCoventryCV48BWUK

Neuroimaging has emerged over the last few decades as a crucial tool in diagnosing Alzheimer’s disease(AD).Mild cognitive impairment(MCI)is a condition that falls between the spectrum of normal cognitive function and ***,previous studies have mainly used handcrafted features to classify MCI,AD,and normal control(NC)*** paper focuses on using gray matter(GM)scans obtained through magnetic resonance imaging(MRI)for the diagnosis of individuals with MCI,AD,and *** improve classification performance,we developed two transfer learning strategies with data augmentation(i.e.,shear range,rotation,zoom range,channel shift).The first approach is a deep Siamese network(DSN),and the second approach involves using a cross-domain strategy with customized *** performed experiments on the Alzheimer’s Disease Neuroimaging Initiative(ADNI)dataset to evaluate the performance of our proposed *** experimental results demonstrate superior performance in classifying the three binary classification tasks:NC ***,NC ***,and MCI ***,we achieved a classification accuracy of 97.68%,94.25%,and 92.18%for the three cases,*** study proposes two transfer learning strategies with data augmentation to accurately diagnose MCI,AD,and normal control individuals using GM *** findings provide promising results for future research and clinical applications in the early detection and diagnosis of AD.

关键词： Alzheimer’s disease mild cognitive impairment normal control transfer learning classification augmentation

Peptides-based vaccine against SARS-nCoV-2 antigenic fragmented synthetic epitopes recognized by T cell and β-cell initiation of specific antibodies tofightthe infection

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Bio-Design and Manufacturing 2021年第3期4卷 490-505页

作者： Zainularifeen Abduljaleel Faisal A.Al-Allaf syed A.aziz Department of Medical Genetics Faculty of MedicineUmm Al-Qura UniversityP.O.Box715Mecca21955Kingdom of Saudi Arabia Science and Technology Unit UmmAl-Qura UniversityP.O.Box 715Mecca21955Kingdom of SaudiArabia The Regional Laboratory Molecular Diagnostics UnitDepartment of Molecular BiologyMinistry of Health(MOH)P.O.Box 6251MeccaKingdom of SaudiArabia Department of Pathology and Lab Medicine University of Ottawa451Smyth RoadOttawaONK1H8M5Canada

The World Health Organization has declared the rapidly spreading coronavirus to be a global *** FDA is yet to approve a vaccine for human novel ***,we developed a peptide-based vaccine and used high-throughput screening by molecular dynamics simulation to identify T-cell-and p-cell-recognized epitopes for producing specific antibod-ies against *** construct~12 P'antigenic epitope peptides to develop a more effective vaccine and identify specific *** epitope peptides selectively presented the best antigen presentation scores for both human pMHC class I and II alleles to develop a strong binding *** antigens identified of SARS-nCoV-2 different proteins by each attached specific~1-7 L linker adaptor were used to construct a broad single peripheral peptide *** is expected to be highly antigenic with a minimum allergic *** a result of these exciting outcomes,expressing a vaccine using the intimated peptide was highly promising and positive to be highly proposed as epitope-based peptide vaccine of specific antibody against SARS-nCoV-2 by initiating T cells and β-*** in vitro study for the proposed peptide-based vaccine *** *** clinical trials are required to check the efficacy of this vaccine.

关键词： COVID-19 SARS-nCoV-2 Peptide-based vaccine Cell-penetrating peptides Lipid membrane Vaccine efficacy

Conservation laws,Lie symmetries,self adjointness,and soliton solutions for the Selkov–Schnakenberg system

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Communications in Theoretical Physics 2024年第2期76卷 29-44页

作者： Kashif Ali Aly R Seadawy syed T R Rizvi Noor aziz Department of Mathematics COMSATS University IslamabadLahore CampusPakistan Mathematics Department Faculty of ScienceTaibah UniversityAl-Madinah Al-Munawarah41411Saudi Arabia

In this article,we explore the famous Selkov–Schnakenberg(SS)system of coupled nonlinear partial differential equations(PDEs)for Lie symmetry analysis,self-adjointness,and conservation ***,miscellaneous soliton solutions like dark,bright,periodic,rational,Jacobian elliptic function,Weierstrass elliptic function,and hyperbolic solutions of the SS system will be achieved by a well-known technique called sub-ordinary differential *** these results are displayed graphically by 3D,2D,and contour plots.

关键词： Selkov-Schnakenberg system Lie symmetry analysis conservation laws adjointness integrability

Metabolic investigations in patients with hepatitis B and C

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World Journal of Gastroenterology 2010年第5期16卷 603-607页

作者： Abdul aziz Mastoi Bikha Ram Devrajani syed Zulfiquar Ali shah Qasim Rohopoto Sikander Ali Memon Marya Baloch Ghulam Ali Qureshi Waqas Sami M.A.Kazi Institute of Chemistry University of SindJamshoro 75000Pakistan Department of Medicine Liaquat University of Medical and Health SciencesJamshoro 75000Pakistan Medical Research Centre Liaquat University of Medical and Health SciencesJamshoro 75000 Pakistan Department of Biochemistry University of Health SciencesLahore 54600Pakistan

AIM:To investigate the similarities and dissimilarities in patients with hepatitis B and hepatitis C,clinically and metabolically. METHODS:Fifty patients with hepatitis B virus and hepatitis C virus infection were included in this study, along with fifty healthy controls for comparison *** blood(10 mL)samples from patients and healthy subjects were collected and made to clot before serum was separated and immediately levels of the enzymes,alkaline phosphatase(ALK),creatinine phosphokinase(CPK),lactate dehydrogenase (LDH),serum glutamate oxaloacetate transaminase(sGOT)and serum glutamate pyruvate transaminase(sGPT)were determined by a kit *** total con-tent of each metal the serum samples were analyzed using atomic absorption *** of cholesterol,triglycerides,urea,creatinine and uric acid were determined using a kit method on Microlab 300. RESULTS:Serum magnesium and copper levels remained unchanged,whereas the concentration of zinc decreased and iron increased significantly in both groups of *** antioxidant activity was significantly decreased in both hepatitis B and *** the enzymes analyzed,ALK,s-GPT,LDH and s-GOT were all significantly increased in both patients with hepatitis B and C whereas CPK was significantly decreased in patients with hepatitis B and remained unchanged in patients with hepatitis C. CONCLUSION:The information accumulated by this study will help provide a better understanding of involved metabolic processes in order to design appropriate therapeutic approaches for treating these patients,so they can recover and lead normal lives.

关键词： Hepatitis B virus Hepatitis C virus Antioxidant activity Metal content Enzyme activity

Dynamical Analysis of Radiation and Heat Transfer on MHD Second Grade Fluid

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Computer Modeling in Engineering & Sciences 2021年第11期129卷 689-703页

作者： aziz-Ur-Rehman Muhammad Bilal Riaz syed Tauseef Saeed Shaowen Yao Department of Mathematics University of Management and TechnologyLahore54770Pakistan Institute for Groundwater Studies(IGS) University of the Free StateBloemfontein9301South Africa Department of Science&Humanities National University of Computer and Emerging SciencesLahore54000Pakistan School of Mathematics and Information Science Henan Polytechnic UniversityJiaozuo454000China

Convective flow is a self-sustained flow with the effect of the temperature *** density is non-uniform due to the variation of *** effect of the magnetic flux plays a major role in convective *** process of heat transfer is accompanied by a mass transfer process;for instance,condensation,evaporation,and chemical *** to the applications of the heat and mass transfer combined effects in a different field,the main aim of this paper is to do a comprehensive analysis of heat and mass transfer of MHD unsteady second-grade fluid in the presence of ramped boundary conditions near a porous *** dynamical analysis of heat transfer is based on classical differentiation with no memory *** non-dimensional form of the governing equations of the model is *** are solved by the classical integral(Laplace)transform technique/method with the convolution theorem and closed-form solutions are attained for temperature,concentration,and *** physical aspects of distinct parameters are discussed via graph to see the influence on the fluid concentration,velocity,and *** results suggest that the velocity profile decrease by increasing the Prandtl *** existence of a Prandtl number may reflect the control of the thickness of momentum and enlargement of thermal ***,to validate our results,some results are recovered from the literature.

关键词： Heat transfer magnetic effect ramped conditions porous medium Laplace transform thermal radiation

Gastric precancerous lesions are associated with gene variants in Helicobacter pylori -susceptible ethnic Malays

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World Journal of Gastroenterology 2013年第23期19卷 3615-3622页

作者： Sathiya Maran Yeong Yeh Lee Shuhua Xu Nur-Shafawati Rajab Norhazrini Hasan syed Hassan syed Abdul aziz Noorizan Abdul Majid Bin Alwi Zilfalil Human Genome Center School of Medical Sciences Universiti Sains Malaysia16150 Kubang Kerian Malaysia Department of Medicine School of Medical Sciences Universiti Sains Malaysia16150 Kubang Kerian Malaysia Max Planck Independent Research Group on Population Genomics Chinese Academy of Sciences and Max Planck Society Partner Institute for Computational Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences200031 Shanghai China Department of Immunology School of Medical Sciences Universiti Sains Malaysia16150 Kubang Kerian Malaysia Department of Surgery School of Medical Sciences Universiti Sains Malaysia16150 Kubang Kerian Malaysia Department of Paediatrics School of Medical Sciences Universiti Sains Malaysia16150 Kubang Kerian Malaysia

AIM: To identify genes associated with gastric pre-cancerous lesions in Helicobacter pylori (H. pylori )susceptible ethnic Malays. METHODS: Twenty-three Malay subjects with H. pylori infection and gastric precancerous lesions identified during endoscopy were included as "cases". Thirtyseven Malay subjects who were H. pylori negative and had no precancerous lesions were included as "controls". Venous blood was collected for genotyping with Affymetrix 50K Xba1 kit. Genotypes with call rates 0.5 was considered as significant markers. RESULTS: Of the 23 H. pylori -positive subjects recruited, one sample was excluded from further analysis due to a low genotyping call rate. Of the 22 H. pylori positive samples, atrophic gastritis only was present in 50.0%, complete intestinal metaplasia was present in 18.25%, both incomplete intestinal metaplasia and dysplasia was present in 22.7%, and dysplasia only was present in 9.1%. SNPs rs9315542 (UFM1 gene), rs6878265 (THBS4 gene), rs1042194 (CYP2C19 gene) and rs10505799 (MGST1 gene) were significantly associated with atrophic gastritis, complete intestinal metaplasia, incomplete metaplasia with foci of dysplasia and dysplasia, respectively. Allele frequencies in "cases" vs "controls" for rs9315542, rs6878265, rs1042194 and rs10505799 were 0.4 vs 0.06, 0.6 vs 0.01, 0.6 vs 0.01 and 0.5 vs 0.02, respectively. CONCLUSION: Genetic variants possibly related to gastric precancerous lesions in ethnic Malays susceptible to H. pylori infection were identified for testing in subsequent trials.

关键词： Gastric precancerous lesions Gene polymorphisms Genome-wide association Helicobacter pylori Malays

Gamma irradiation-induced effects on the properties of TiO_2 on fluorine-doped tin oxide prepared by atomic layer deposition

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Nuclear Science and Techniques 2018年第7期29卷 191-197页

作者： syed Mansoor Ali M.S.Algarawi Turki S.ALKhuraiji S.S.Alghamdi Muhammad Hammad aziz M.Isa Department of Physics and Astronomy College of ScienceKing Saud University National Center for Irradiation Technology King Abdulaziz City for Science and Technology Department of Physics COMSATS Institute of Information and Technology Department of Physics Faculty of ScienceUniversity of GujratHafiz Hayat Campus

The effect of gamma irradiation with different doses(25–75 kGy) on TiO_2 thin films deposited by atomic layer deposition has been studied and characterized by X-ray diffraction(XRD),photoluminescence measurements,ultraviolet–visible(UV–Vis) spectroscopy,and impedance *** XRD results for the TiO_2 films indicate an enhancement of crystallization after irradiation,which can be clearly observed from the increase in the peak intensities upon increasing the gamma irradiation *** UV–Vis spectra demonstrate a decrease in transmittance,and the band gap of the TiO_2 thin films decreases with an increase in the gamma irradiation *** Nyquist plots reveal that the overall charge-transfer resistance increases upon increasing the gamma irradiation *** equivalent circuit,series resistance,contact resistance,and interface capacitance are measured by simulation using Z-view *** present work demonstrates that gamma irradiation-induced defects play a major role in the modification of thestructural,electrical,and optical properties of the TiO_2 thin films.

关键词： TiO2 原子层 Gamma 性质氧化物 gamma Nyquist 光致发光

Inhibitory Effects of Several Fluoroquinolones on Feline CYP1A and 3A in Hepatic Microsomes

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Open Journal of Veterinary Medicine 2020年第12期10卷 219-237页

作者： syed Sher shah Sadaat Nasrin Stankzi Mohammad Monir Tawfeeq Farid Ahmad Tanin Amanullah aziz Kazuki Sasaki Department of Clinic Faculty of Veterinary Science Kabul University Kabul Afghanistan Department of Pre Clinic Faculty of Veterinary Science Kabul University Kabul Afghanistan Department of Veterinary Medicine Faculty of Agriculture Tokyo University of Agriculture and Technology Tokyo Japan

In this study, the effects of several fluoroquinolones (FQs), such as Ciprofloxacin (CPFX);Orbifloxacin (OBFX);Norfloxacin (NFX);Ofloxacin (OFX);and Enerofloxacin (EFX) on activities of both Cytochrome P450 1A (CYP1A) and Cytochrome P450 3A (CYP3A) of feline microsomes by in vitro tests were studied. Ethoxyresorufin O-deethylation (EROD) and Midazolam 1' hydroxylation and 4-hydroxylation (MDZ1'H and MDZ4H) were analyzed by High Performance Liquid Chromatography (HPLC). All the FQs inhibited the reactions by a competitive or noncompetitive and irreversible manner. The inhibitory constants (Ki) were as followings: CYP1A;ranged from 0.12 to 1.23 mM for NFX, OBFX, EFX, CPFX, OFX and CYP3A, for MDZ1'H;ranged from 5.8 to 35 and MDZ4H;9 to 29 mM, respectively. As these values are higher by 24 to 200-times of given single clinical dose of serum levels after application of FQs. It indicates that if co-administrated with these FQs by reversible inhibitory manner, the inhibition of CYP1A and CYP3A effect on CYP1A and 3A actions is not very significant to cause drug interaction with above mentioned enzyme substrates. Out of the FQs tested, CPFX and NFX for CYP1A, and CPFX for CYP3A showed irreversible inhibitory effects (time-dependent), so it has been concluded that these drugs may cause drug-drug interaction by accumulation, when they are repeatedly administrated. Since EFX is biotransformed to CPFX by the liver, it could have the identical risk too.

关键词： Several Fluoroquinolones CYP Inhibitors EROD Midazolam Microsomes