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Comparison of resistive index and shear-wave elastography in the evaluation of chronic kidney allograft dysfunction

World Journal of Transplantation 2024年第1期14卷 154-163页

作者： Ameet Kumar Jesrani syed m faiq Rahma Rashid Tariq Ali Kalwar Rehan mohsin Tahir Aziz Nida Amin Khan muhammed mubarak Department of Radiology Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan Department of Pathology Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan Department of Transplantation Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan Department of Urology Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan

BACKGROUND Detection of early chronic changes in the kidney allograft is important for timely intervention and long-term *** and novel ultrasound-based investigations are being increasingly used for this purpose with variable *** To compare the diagnostic performance of resistive index(RI)and shear wave elastography(SWE)in the diagnosis of chronic fibrosing changes of kidney allograft with histopathological *** This is a cross-sectional and comparative study.A total of 154 kidney transplant recipients were included in this study,which was conducted at the Departments of Transplantation and Radiology,Sindh Institute of Urology and Transplantation,Karachi,Pakistan,from August 2022 to February *** consecutive patients with increased serum creatinine levels and reduced glomerular filtration rate(GFR)after three months of transplantation were enrolled in this *** and RI were performed and the findings of these were evaluated against the kidney allograft biopsy results to determine their diagnostic *** The mean age of all patients was 35.32±11.08 *** these,126(81.8%)were males and 28(18.2%)were *** mean serum creatinine in all patients was 2.86±1.68 mg/dL and the mean estimated GFR was 35.38±17.27 mL/min/1.73 *** allograft biopsy results showed chronic changes in 55(37.66%)*** sensitivity,specificity,positive predictive value(PPV),and negative predictive value(NPV)of SWE for the detection of chronic allograft damage were 93.10%,96.87%%,94.73%,and 95.87%,respectively,and the diagnostic accuracy was 95.45%.For RI,the sensitivity,specificity,PPV,and NPV were 76.92%,83.33%,70.17%,and 87.62%,respectively,and the diagnostic accuracy was 81.16%.CONCLUSION The results from this study show that SWE is more sensitive and specific as compared to RI in the evaluation of chronic allograft *** can be of great help during the routine follow-up of kidney transplant recipients for screening a

关键词： Shear wave Sonoelastography Resistive index Chronic allograft changes Biopsy Histopathology

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An efficient permutation approach for SbPN-based symmetric block ciphers

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Cybersecurity 2024年第2期7卷 113-130页

作者： mir Nazish m.Tariq Banday Insha syed Sheena Banday Department of Electronics and Instrumentation Technology University ofKashmirSrinagar 190006India

It is challenging to devise lightweight cryptographic primitives efficient in both hardware and software that can provide an optimum level of security to diverse Internet of Things applications running on low-end constrained ***,an effcient hardware design approach that requires some specific hardware resource may not be effcient if implemented in *** bit Permutation Network based ciphers such as PRESENT and GIFT are effcient,lightweight cryptographic hardware design *** ciphers introduce confusion and diffu-sion by employing a 4×4 static substitution box and bit *** bit-wise permutation is realised by sim-ple rerouting,which is most cost-effective to implement in hardware,resulting in negligible power ***,this method is highly resource-consuming in software,particularly for large block-sized ciphers,with each single-bit permutation requiring multiple *** paper proposes a novel software-based design approach for permutation operation in Substitution bit Permutation Network based ciphers using a bit-banding *** conventional permutation using bit rotation and the proposed approach have been implemented,analysed and compared for GIFT and PRESENT ciphers on ARm Cortex-m3-based LPC1768 development platform with KEIL mDK used as an Integrated Development *** real-time performance comparison between conven-tional and the proposed approaches in terms of memory(RAm/ROm)footprint,power,energy and execution time has been carried out using ULINKpro and ULINKplus debug adapters for various code and speed optimisation *** proposed approach substantially reduces execution time,energy and power consumption for both PRE-SENT and GIFT ciphers,thus demonstrating the effciency of the proposed method for Substitution bit Permutation Network based symmetric block ciphers.

关键词： Lightweight cryptography PRESENT GIFT SbPN Cortex-m LPC1768 Bit-band memory

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Detection of onset of agglomeration in a bubbling fluidized bed biomass combustor using reactive Eulerian computational fluid dynamics

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Particuology 2024年第7期90卷 504-515页

作者： Abdullah Tasleem Atta Ullah Fei Li Qun Yi William Nimmo syed Sheraz Daood Department of Chemical Engineering Pakistan Institute of Engineering and Applied Sciences(PIEAS)Lehtrar RoadP.O.Nilore45650IslamabadPakistan Institute of Process Engineering Chinese Academy of SciencesBeijing100190China School of Chemical Engineering and Pharmacy Wuhan Institute of TechnologyWuhan430205China Energy Engineering Group Energy 2050Department of Mechanical EngineeringUniversity of SheffieldSheffieldS37RDUnited Kingdom Institute of Energy and Environmental Engineering Faculty of ElectricalEnergy&Environmental EngineeringUniversity of the PunjabQuaid-e-Azam CampusLahorePakistan Energy Engineering Research and Development Centre Faculty of ElectricalEnergy&Environmental EngineeringUniversity of the PunjabQuaid-e-Azam CampusLahorePakistan

The choice of a type of combustion technology to be used for heat or power generation depends on economic,technical,operational and fuel availability *** benefits associated with the evolving market driven by the fluidised bed combustion(FBC)technology cannot be overlooked especially when gauged at 65 GWth of worldwide installed capacity alongside added benefits of handling fuel variation,low pollutant emissions and high combustion *** or biomass waste will continue to have a vital role to play in the future FBC technology-based power *** often contains high levels of inorganic species that can form sticky agglomerates posing a significant risk to boiler operation resulting in unscheduled *** added complexity of the behaviour of the fuel and bed material mix highlights the requirement for simulation models to identify agglomeration to help improve the overall performance and reliability of FBC *** resolve this problem,this research devised a simulation strategy for the detection of agglomeration using the Eulerian–Eulerian *** developed modelling strategy is validated with the experimental data available in literature for two-dimensional simplified geometry of a pilot-scale fluidised bed *** model results were found promising and robust to predict bed defluidisation times and other parameters consistent with the experimental data.

关键词： Fluidized bed combustion Eulerian models Biomass Agglomeration Defluidisation

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A review:Health benefits and physicochemical characteristics of blended vegetable oils

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Grain & Oil Science and Technology 2024年第2期7卷 113-123页

作者： Hina Daud memon Sarfaraz Ahmed mahesar Sirajuddin Huseyin Kara syed Tufail Hussain Sherazi mohammad Younis Talpur National Centre of Excellence in Analytical Chemistry University of SindhJamshoro 76080Pakistan International Center for Chemical and Biological Sciences HEJ Research Institute of ChemistryUniversity of KarachiKarachi 75270Pakistan Department of Chemistry Faculty of ScienceSelcuk UniversityKonya 42075Turkey Dr.m.A.Kazi Institute of Chemistry University of SindhJamshoro 76080Pakistan

Oil blending is the method of choice used worldwide to improve oxidative stability and nutritional *** is no such edible oil/fat that meets all the recommendations from the health point of *** fatty acid composition of vegetable oils decides the fate of the *** single oil is unable to provide a balanced amount of fatty acids(FAs)required/recommended on a daily intake *** oils/fats is an appropriate procedure of physically mixing multiple oils in suitable proportions which may provide functional lipids with improved antioxidant potential and desirable physical and chemical *** review piled up the accessible data on the blending of diverse oils/fats in the combination of binary,ternary,quaternary,or other types of oils into a single blended *** can be found very convincing towards appropriate FA profile,enhancement in physicochemical characteristics,and augmented stability for the period of storage or when used as cooking/frying processes which could ultimately serve as an effectual dietary intervention towards the health protectiveness.

关键词： Vegetable oil Oil blending Physicochemical properties Nutritional benefits

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Hybrid IPOm: A Novel Technique for the management of Incisional Hernia

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Surgical Science 2024年第3期15卷 125-134页

作者： syed Asim Yamin Shahnawaz Ahangar Fadi Albadawi Abdullah Alqarni Abdulaziz m. Alzahrani Department of Specialised Surgery King Abdullah Medical City Hospital Makkah Saudi Arabia

Background and Aim: The incidence of incisional hernias has been reported to be around 15%. In the present scenario, a wide array of surgical procedures are available for their better management. In this study, we intend to share our experience with one novel technique, “Hybrid IPOm (Intraperitoneal onlay meshplasty)” as a management option for a selected cohort of patients. methods: This prospective study was undertaken during January 2019 to July 2023 at King Abdullah medical city, makkah. A total of 51 cases were selected for Hybrid IPOm repair as per inclusion criteria;medium sized (4 - 10 cm) hernia defects;uncomplicated hernias;age more than 18 years. The follow-up period of the patients varied from 6 months to 4 years. The operation commenced with open hernia dissection, mesh deployment into abdomen, defect closure and then conversion to laparoscopy for the posterior mesh placement. Results: A total of 51 cases were repaired successfully with this technique. 48 out of 51 cases were incisional hernias secondary to some primary procedure done either for hernias itself or some other intra-abdominal pathology. The three cases were primary hernias falling in medium to large category with unaesthetic overlying skin. The age range was 19 to 72 years. The mean (range) operative time was 135 (90 - 240) min, and the average blood loss was 70 ml. The mean (range) hospital stay was 3 (2 - 11) days. All patients returned to routine work within 2 - 3 weeks of surgery. The median follow-up was 15 (6 - 48) months. Of the 51 cases, 3 patients developed seroma (managed conservatively), 1 patient developed a large hematoma (needed evacuation), and 1 patient developed superficial wound infection (managed with antibiotics). Two patients had recurrences;one patient had previously failed multiple repairs, and the other developed a postoperative hematoma. None of our patients had an iatrogenic bowel injury. Conclusion: Hybrid IPOm technique is a safe, feasible and easily reproducibl

关键词： Incisional Hernias Hybrid Surgery Open to Laparoscopic Conversion Safety Feasibility

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Comprehensive analysis of the role of ubiquitin-specific peptidases in colorectal cancer:A systematic review

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World Journal of Gastrointestinal Oncology 2024年第1期16卷 197-213页

作者： Eman Al-Balushi Amina Al marzouqi Shima Tavoosi Amir Hossein Baghsheikhi Arash Sadri Leyla Sharifi Aliabadi mohammad-mahdi Salarabedi syed Azizur Rahman Nabeel Al-Yateem Alireza mosavi Jarrahi Aram Halimi mohammad Ahmadvand Wael m Abdel-Rahman College of Health Sciences University of SharjahSharjah 27272United Arab Emirates Department of Biology Faculty of SciencesUniversity of IsfahanIsfahan 81746-73441Iran Department of Biology Science and Research BranchIslamic Azad UniversityTehran 11365/4435Iran Students’Scientific Research Center Tehran University of Medical SciencesTehran ***Iran Cell Therapy and Hematopoietic Stem Cell Transplantation Research Center Research Institute for OncologyHematologyand Cell TherapyTehran University of Medical SciencesTehran ***Iran Student Research Committee School of MedicineShahid Beheshti University of Medical SciencesTehran ***Iran Department of Nursing University of SharjahSharjah 27272United Arab Emirates Cancer Research Centre Shahid Beheshti University of Medical SciencesTehran ***Iran Department of medical Laboratory Sciences University of SharjahSharjah 27272United Arab Emirates

BACKGROUND Colorectal cancer(CRC)is the third most frequent and the second most fatal *** search for more effective drugs to treat this disease is ongoing.A better understanding of the mechanisms of CRC development and progression may reveal new therapeutic ***-specific peptidases(USPs),the largest group of the deubiquitinase protein family,have long been implicated in various *** have been numerous studies on the role of USPs in CRC;however,a comprehensive view of this role is *** To provide a systematic review of the studies investigating the roles and functions of USPs in *** We systematically queried the mEDLINE(via Pubmed),Scopus,and Web of Science *** Our study highlights the pivotal role of various USPs in several processes implicated in CRC:Regulation of the cell cycle,apoptosis,cancer stemness,epithelial–mesenchymal transition,metastasis,DNA repair,and drug *** findings of this study suggest that USPs have great potential as drug targets and noninvasive biomarkers in *** dysregulation of USPs in CRC contributes to drug resistance through multiple *** Targeting specific USPs involved in drug resistance pathways could provide a novel therapeutic strategy for overcoming resistance to current treatment regimens in CRC.

关键词： Ubiquitin-specific peptidases Colorectal cancer Deubiquitinase protein family Drug target discovery Biomarker discovery

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Discharging patients home from the intensive care unit:A new trend

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World Journal of Clinical Cases 2024年第23期12卷 5313-5319页

作者： Esraa m Hassan Abbas B Jama Ahmed Sharaf Asim Shaikh mohamad El Labban Salim Surani syed A Khan Department of Critical Care medicine Mayo Clinic Health systemMankatoMN 56001United States Department of Internal medicine Baptist Hospital of Southeast TexasBeaumontTX 77701United States Department of medicine Aga Khan UniversityKarachi 74200SindhPakistan Department of Internal medicine Mayo Clinic Health SystemMankatoMN 56001United States Department of medicine and Pharmacology Texas A&M UniversityCollege StationTX 77843United States Department of Anaesthesiology Mayo Clinic Health SystemRochesterMN 55905United States

Discharging patients directly to home from the intensive care unit(ICU)is becoming a new *** review examines the feasibility,benefits,challenges,and considerations of directly discharging ICU *** analyzing available evidence and healthcare professionals'experiences,the review explores the potential impacts on patient outcomes and healthcare *** practice of direct discharge from the ICU presents both opportunities and *** it can potentially reduce costs,enhance patient comfort,and mitigate complications linked to extended hospitalization,it necessitates meticulous patient selection and robust post-discharge support *** this strategy successfully mandates the availability of home-based care services and a careful assessment of the patient's readiness for the *** critical evaluation of existing literature,this review underscores the significance of tailored patient selection criteria and comprehensive post-discharge support systems to ensure patient safety and optimal *** insights provided contribute evidence-based recommendations for refining the direct discharge approach,fostering improved patient outcomes,heightened satisfaction,and streamlined healthcare ***,the review seeks to balance patientcentered care and effective resource utilization within ICU discharge strategies.

关键词： Intensive care unit Critical care Early discharge Cost effective critical care Patient comfort Early recovery

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光驱动Rh/InGaN_(1-x)O_(x)纳米组装体甲烷干重整制合成气

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Science Bulletin 2024年第10期69卷 1400-1409页

作者：李亦昕李景林俞天奇邱亮 syed m.Najib Hasan 姚琳潘虎 Shamsul Arafin Sharif md.Sadaf 朱磊周宝文 Key Laboratory for Power machinery and Engineering of ministry of Education Research Center for Renewable Synthetic FuelSchool of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China China-UK Low Carbon College Shanghai Jiao Tong UniversityShanghai 201306China Centre Energie Matériaux et TélécommunicationsInstitut National de la Recherche Scientifique(INRS)-Universitédu QuébecVarennes J3X 1E4Canada Department of Electrical and Computer Engineering The Ohio State UniversityColumbusOH43210USA

Light-driven dry reforming of methane toward syngas presents a proper solution for alleviating climate change and for the sustainable supply of transportation fuels and ***,Rh/InGaN_(1-x)O_(x) nanowires supported by silicon wafer are explored as an ideal platform for loading Rh nanoparticles,thus assembling a new nanoarchitecture for this grand *** combination with the remarkable photothermal synergy,the O atoms in Rh/InGaN_(1-x)O_(x) can significantly lower the apparent activation energy of dry reforming of methane from 2.96 eV downward to 1.70 *** as-designed Rh/InGaN_(1-x)O_(x) NWs nanoarchitecture thus demonstrates a measurable syngas evolution rate of 180.9 mmol g_(cat)^(-1) h^(-1) with a marked selectivity of 96.3% under concentrated light illumination of 6 W cm^(-2).What is more,a high turnover number(TON)of 4182 mol syngas per mole Rh has been realized after six reuse cycles without obvious activity *** correlative 18O isotope labeling experiments,in-situ irradiated X-ray photoelectron spectroscopy(ISI-XPS)and in-situ diffuse reflectance Fourier transform infrared spectroscopy characterizations,as well as density functional theory calculations reveal that under light illumination,Rh/InGaN_(1-x)O_(x) NWs facilitate releasing^(*)CH_(3) and H^(+)from CH_(4) by holes,followed by H_(2) evolution from H^(+)reduction with ***,the O atoms in Rh/InGaN_(1-x)O_(x) can directly participate in CO generation by reacting with the ^(*)C species from CH_(4) dehydrogenation and contributes to the coke elimination,in concurrent formation of O *** resultant O vacancies are then replenished by CO_(2),showing an ideal chemical *** work presents a green strategy for syngas production via light-driven dry reforming of methane.

关键词： Dry reforming of methane Photo-thermal catalysis Rh/InGaN_(1-x)O_(x)nanowires

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Optimized Generative Adversarial Networks for Adversarial Sample Generation

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Computers, materials & Continua 2022年第8期72卷 3877-3897页

作者： Daniyal m.Alghazzawi syed Hamid Hasan Surbhi Bhatia Faculty of Computing and Information Technology King Abdulaziz UniversityJeddah21589Saudi Arabia Department of Information Systems College of Computer Sciences and Information TechnologyKing Faisal UniversitySaudi Arabia

Detecting the anomalous entity in real-time network traffic is a popular area of research in recent *** few researches have focused on creating malware that fools the intrusion detection system and this paper focuses on this *** are using Deep Convolutional Generative Adversarial Networks(DCGAN)to trick the malware classifier to believe it is a normal *** this work,a new dataset is created to fool the Artificial Intelligence(AI)based malware detectors,and it consists of different types of attacks such as Denial of Service(DoS),scan 11,scan 44,botnet,spam,User Datagram Portal(UDP)scan,and ssh *** discriminator used in the DCGAN discriminates two different attack classes(anomaly and synthetic)and one normal *** model collapse,instability,and vanishing gradient issues associated with the DCGAN are overcome using the proposed hybrid Aquila optimizer-based mine blast harmony search algorithm(AO-mBHS).This algorithm helps the generator to create realistic malware samples to be undetected by the *** performance of the proposed methodology is evaluated using different performance metrics such as training time,detection rate,F-Score,loss function,Accuracy,False alarm rate,*** superiority of the hybrid AO-mBHS based DCGAN model is noticed when the detection rate is changed to 0 after the retraining method to make the defensive technique hard to be noticed by the malware detection *** support vector machines(SVm)is used as the malicious traffic detection application and its True positive rate(TPR)goes from 80%to 0%after retraining the proposed model which shows the efficiency of the proposed model in hiding the samples.

关键词： Aquila optimizer convolutional generative adversarial networks mine blast harmony search algorithm network traffic dataset adversarial artificial intelligence techniques

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Unstructured Oncological Image Cluster Identification Using Improved Unsupervised Clustering Techniques

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Computers, materials & Continua 2022年第7期72卷 281-299页

作者： S.Sreedhar Kumar syed Thouheed Ahmed Qin Xin S.Sandeep m.madheswaran syed muzamil Basha Dr.T.Thimmaiah Institute of Technology VTUKGFKarnatakaIndia School of Computing&Information Technology REVA UniversityBengaluruIndia Faculty of Science and Technology University of the Faroe IslandsFaroe IslandsDenmark K S School of Engineering BengaluruIndia muthayammal Engineering College RasipuramTamil NaduIndia

This paper presents,a new approach of medical Image Pixels Clustering(mIPC),aims to trace the dissimilar patterns over the magnetic Resonance(mR)image through the process of automatically identify the appropriate number of distinct clusters based on different improved unsupervised clustering schemes for enrichment,pattern predication and deeper *** proposed mIPC consists of two stages:clustering and *** the clustering stage,the mIPC automatically identifies the distinct number of dissimilar clusters over the gray scale mR image based on three different improved unsupervised clustering schemes likely improved Limited Agglomerative Clustering(iLIAC),Dynamic Automatic Agglomerative Clustering(DAAC)and Optimum N-means(ONm).In the second stage,the performance of mIPC approach is estimated by measuring Intra intimacy and Intra contrast of each individual cluster in the result of mR image based on proposed validation method namely Shreekum Intra Cluster measure(SICm).Experimental results showthat the mIPC approach is better suited for automatic identification of highly relative dissimilar clusters over the mR cancer images with higher Intra closeness and lower Intra contrast based on improved unsupervised clustering schemes.

关键词： magnetic resonance image unsupervised clustering scheme intra intimacy intra contrast iLIAC shreekum intra cluster measure medical image clustering

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