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伴有眼部及脑部异常的双侧颜面部毛细血管畸形

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世界核心医学期刊文摘（皮肤病学分册） 2006年第11期2卷 41-41页

作者： Mazereeuw-Hautier J. syed S. Harper J.I. 周炳荣 Service de Dermatologie Hopital¨ Rangueil TSA 50032 1 Av Jean Poulhès 31059 Toulouse Cedex 9 FranceDr.

Objective: To establish whether the prognosis of bilateral facial capillary malformation (BFCM) is worse compared with that of unilateral facial port-wine stain. Design: Retrospective study. Setting: Paediatric Dermatology Department, Great Ormond Street Hospital for Children NHS Trust, a tertiary referral center for vascular anomalies. Patients: A cohort of 350 children who presented with facial CM was seen between January 1, 1994, and June 30, 2004. Twenty-seven children with BFCM were identified. A control group of 27 children with unilateral CM was randomly selected from the total cohort. Main Outcome Measures: Demographic, clinical, and radiographic characteristics were recorded and compared between the 2 groups: age at presentation, sex, distribution, extension, extrafacial lesions, glaucoma, ipsilateral leptomeningeal angiomatosis, and epilepsy. The recorded informationwas collected from the database of the Paediatric Dermatology Department, the hospital records, and the patients’photographs. Results: Compared with the 27 children with unilateral facial CM, the 27 with BFCM showed a higher frequency of association with extrafacial lesions (17 [63%] vs 6 [22%]), glaucoma (21 [78%]-vs 2 [7%]), and ipsilateral leptomeningeal angiomatosis (14[52%] vs 2 [7%]). All patients who had BFCM with bilateral and complete involvement of the ophthalmic area had ipsilateral leptomeningeal angiomatosis. Conclusion: Patients with BFCM must be considered as a group with a worse prognosis compared with patients with unilateral facial CM.

关键词：毛细血管畸形脑膜血管瘤病皮肤病科皮损分布脉管畸形卫生服务发病年龄人口统计学曼德日至

水稻临界氮浓度稀释模型及氮素营养诊断研究（摘要）

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中国稻米 2013年第4期19卷 149-149页

作者：刘小军 syed Tahir Ata-Ul-Karim 陆震洲曹卫星朱艳南京农业大学国家信息农业工程技术中心江苏省信息农业高技术研究重点实验室南京210095

开展水稻临界氮浓度稀释模型及营养诊断研究，可为明确水稻生长过程中氮素状况的变化规律，实现作物氮素状况的科学诊断和追肥调控，进而提高氮素利用效率、改善作物产量和品质提供理论依据和技术指导。本研究于2009—2011年在江苏省仪... 详细信息

开展水稻临界氮浓度稀释模型及营养诊断研究，可为明确水稻生长过程中氮素状况的变化规律，实现作物氮素状况的科学诊断和追肥调控，进而提高氮素利用效率、改善作物产量和品质提供理论依据和技术指导。本研究于2009—2011年在江苏省仪征市开展了3年的水稻小区试验，

关键词：氮素营养诊断临界氮浓度水稻模型稀释摘要氮素利用效率氮素状况

有病理学的破裂的 humeri 的双边的主要黄瘤: 一份案例报告

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World Journal of Radiology 2013年第9期5卷 345-348页

作者： Sayed Ali Alex Fedenko Ali B syed George Matcuk Dakshesh Patel Chris Gottsegen Eric White Department of Radiology Temple University Hospital Department of Pathology University of Southern California Keck School of Medicine Department of Radiology University of Southern California Keck School of Medicine

Xanthomas are rare bone tumors that occur more often in the appendicular skeleton and typically appear radiographically benign,with a narrow zone of transition and a sclerotic *** report the case of a 57-year-old woman with hyperlipidemia presenting with bilateral shoulder pain after minor *** and histopathologic investigation demonstrated intraosseous xanthoma with atypical features,including multifocality,a wide zone of transition and pathologic fractures-characteristics more commonly associated with aggressive lesions such as multiple myeloma or *** diagnosis,imaging,and histological appearance of xanthoma of bone are reviewed.

关键词： Xanthoma Hyperlipidemia Pathologic fracture

应用国立眼科研究所的25项目视觉功能问卷调查视网膜中央静脉阻塞患者与视觉相关的生活质量

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美国医学会眼科杂志（中文版） 2004年第2期16卷 128-128页

作者： VincentA.Deramo TerryA.Cox ArjumandB.syed PaulP.Lee SharonFekrat 李爱军

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眼睑斑痣性迷芽瘤1例

世界核心医学期刊文摘（皮肤病学分册） 2005年第1期1卷 43-43页

作者： Szyfelbein K. Kozakewicz H.P.W. syed N.A. Zembowicz A. 张宪旗 Dermatopathology Unit Massachusetts General Hospital 820 Warren Bldg. 55 F ruit Street Boston MA 02114 United States Dr.

Phakomatous choristoma is a rare congenital hamartoma of lens *** prese nts in newborns or young infants as a subcutaneous mass in the medial lower eyel *** present a case of phakomatous choristoma recently identified among old co nsultation files at Childrens Hospital in *** case illustrates unique histological features of this entity which has to be included in differential di agnosis of skin lesions of the inferonasal eyelid.

关键词：斑痣迷芽瘤错构瘤皮下肿块儿童医院鉴别诊断文章报道特异性

Immunohistochemical Expression of Biomarkers and Human Papilloma Virus Infection in Esophageal Squamous Cell Carcinoma Patients of Pakistan-HPV and Biomarkers in ESCC

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国际感染病学（电子版） 2019年第1期8卷 1-7页

作者： S.M.Adnan Ali Yumna Mirza M.Ozair Awan K.M.Inam Pal Zubair Ahmad Office of Academia and Research in Surgery Department of SurgeryAga Khan University Hospital Medical College Aga Khan University Hospital Section of General Surgery Department of SurgeryAga Khan University Hospital Section of Histopathology Department of Pathology and Laboratory MedicinesAga Khan University Hospital

Objective To determine HPV infection status and expression of p16, cyclooxygenase-2(COX-2), Cyclin D1 and epidermal growth factor receptor(EGFR) in ESCC patients of Pakistan. Methods 51 ESCC patients treated at Aga Khan University Hospital(AKUH) were included. HPV infection status was confirmed via PCR while the expression of the four biomarkers was determined using immunohistochemistry. The correlation of all markers with patient clinicopathological features as well as each other was analyzed. Results HPV infection status and p16 overexpression was found to be negative in all the patients while COX-2, Cyclin D1 and EGFR were overexpressed in 56.9%, 62.7% and 49.0% of the patients respectively. COX-2 showed a significant correlation with tumor invasion while EGFR was shown to be significantly correlated with histological grading and COX-2 expression. Conclusion COX-2 and EGFR can be used as prognostic markers. HPV does not seem to be a causative agent for ESCC in Pakistan.

关键词： COX-2 Cyclin D1 EGFR ESCC HPV

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巴基斯坦原发性耐多药结核病流行情况

国际结核病与肺部疾病杂志 2008年第2期3卷 73-77页

作者： A.Javaid R.Hasan A.Zafar A.Ghafoor A.J.Pathan A.Rab A.Sadiq C.M.Akram I.Burki K.Shah M.Ansari N.Rizvi S.U.Khan S.R.Awan Z.A.syed Z.H.lqbal Z.Shaheen N.ur Rehman 邢超 Department of Pulmonology Postgraduate Medical InstituteLady Reading Hospital Peshawar Department of Microbiology Agha Khan University HospitalKarachi TB Control Programme North West Frontier Province(NWFP)Peshawar Institute of Chest Diseases Kotri Department of Pulmonology Ayub Teaching HospitalAbbotabad Oiha Institute of Chest Diseases Karachi Gulab Devi Hospital Lahore Lyari General Hospital Karachi National TB Control Programme Islamabad Liaqat National Hospital Karachi Jinnah Postgraduate Medical Centre Karachi King Edwards Medical University Lahore Nishtar Medical College Multan Allama Iqbal Medical Lahore Wyeth(Pvt) Limited KarachiPakistan

背景:巴基斯坦是世界第6位结核病高负担国家。据世界卫生组织(WHO)估计,巴基斯坦结核病发病率为181/10万,全国每年新增结核病患者28.6万例。来自于医院的资料表明:巴基斯坦耐多药结核病(MDR-TB)问题已十分严重,急需在社区水平对耐多药... 详细信息

背景:巴基斯坦是世界第6位结核病高负担国家。据世界卫生组织(WHO)估计,巴基斯坦结核病发病率为181/10万,全国每年新增结核病患者28.6万例。来自于医院的资料表明:巴基斯坦耐多药结核病(MDR-TB)问题已十分严重,急需在社区水平对耐多药结核病的严重程度开展评估。本研究为针对巴基斯坦耐药结核病流行状况开展的横段面研究,所使用的痰标本来自于巴基斯坦全国742例未经治疗的新诊断的肺结核患者。目的:评估巴基斯坦原发性耐药的流行情况结果:在672例痰培养阳性患者中,有76例(11.3%)出现了对1种或多种抗结核药物耐药。36例(5.4%)患者对链霉素(10μg/ml)耐药; 51例(7.6%)患者对异烟肼(1μg/ml)耐药;15例(2.2%)患者对利福平(5μg/ml)耐药;12例(1.8%)患者对乙胺丁醇(10μg/ml)耐药;22例(3.3%)患者对吡嗪酰胺耐药。有46例(6.8%)患者痰标本中分离的结核菌株耐1种抗结核药物, 10例(1.5%)同时耐2种抗结核药物,12例(1.8%)同时耐3种抗结核药物,6例(0.9%)同时耐4种抗结核药物,2例(0.3%)同时耐全部5种抗结核一线药。原发性耐多药率为1.8%,(n= 12)(异烟肼1μg/ml,利福平5μg/ml)。结论:研究结果表明,巴基斯坦原发性耐多药率<2%,需要进一步实施有效的DOTS策略。

关键词：原发性耐药耐多药结核病巴基斯坦

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《回眸》

山东工艺美术学院学报 2018年第6期 38-38页

作者：塞德·贾维尔·A卡济

Association of gene variants with susceptibility to type 2 diabetes among Omanis

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World Journal of Diabetes 2015年第2期6卷 358-366页

作者： Sawsan Al-Sinani Nicolas Woodhouse Ali Al-Mamari Omaima Al-Shafie Mohammed Al-Shafaee Said Al-Yahyaee Mohammed Hassan Deepali Jaju Khamis Al-Hashmi Mohammed Al-Abri Khalid Al-Rassadi syed Rizvi Yengo Loic Philippe Froguel Riad Bayoumi Department of Biochemistry College of Medicine and Health SciencesSultan Qaboos University Genomics and Metabolic Disease Institute Pasteur of Lille Lille2 University

AIM:To investigate the association of 10 known common gene variants with susceptibility to type 2diabetes mellitus(T2D)among ***:Using case-control design,a total of992 diabetic patients and 294 normoglycemic Omani Arabs were genotyped,by an allelic discrimination assay-by-design TaqMan method on fast real time polymerase chain reaction system,for the following gene variants:KCNJ11(rs5219),TCF7L2(rs7903146),CDKAL1(rs10946398),CDKN2A/B(rs10811661),FTO(rs9939609 and rs8050136),IGF2BP2(rs4402960),SLC30A8(rs13266634)CAPN10(rs3792267)and HHEX(rs1111875).T2D patients were recruited from the Diabetes Clinic(n=243)and inpatients(n=749)at Sultan Qaboos Univesity Hospital(SQUH),Muscat,*** control participants(n=294)were volunteers from the community and from those visiting Family Medicine Clinic at SQU,for regular medical *** difficulty in recruiting Omani participants with no family history of diabetes was the main reason behind the small number of control participants in this *** all volunteers questioned had a relativewith diabetes *** of the small number of normoglycemic controls in this study,this sample was sufficient for detection of genes and loci for common alleles influencing T2D with an odds ratio of≥1.3reaching at least 80%*** was collected from June 2010 to February ***:Using binary logistic regression analysis,four gene variants showed significant association with T2D risk:KCNJ11(rs5219,P=5.8×10^(-6),OR=1.74),TCF7L2(rs7903146,P=0.001,OR=1.46),CDKAL1(rs10946398,P=0.002,OR=1.44)and CDKN2A/B(rs10811661,P=0.020,OR=1.40).The fixation index analysis of these four gene variants indicated significant genetic differentiation between diabetics and controls{[KCNJ11(rs5219),P<0.001],[TCF7L2(rs7903146),P<0.001],[CDKAL1(rs10946398),P<0.05],[CDKN2A/B(rs10811661),P<0.05]}.The highest genotype variation%between diabetics and controls was found at KCNJ11(2.07%)and TCF7L2(1.62%).This study was not able to detect an as

关键词： Type 2 diabetes Genetics Oman Casecontrol Association Gene Variants