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Rice-wheat comparative genomics:gains and gaps

The Crop Journal 2024年第3期12卷 656-669页

作者： Akila Wijerathna-Yapa Ruchi Bishnoi Buddhini Ranawaka Manu Maya Magar Hafeez Ur Rehman swati g.bharad Michal T.Lorenc Vinita Ramtekey Sasha gohar Charu Lata Md.Harun-Or-Rashid Maryam Razzaq Muhammad Sajjad Bhoja *** School of Agriculture and Food Sustainability The University of QueenslandSt LuciaQLD 4072Australia ARC Centre of Excellence for Plant Success in Nature and Agriculture The University of QueenslandSt LuciaQLD 4072Australia Department of genetics and Plant Breeding College of AgricultureUmmedganj-KotaAgriculture UniversityKotaRajasthan 324001India Centre for Agriculture and the Bioeconomy Queensland University of Technology(QUT)2 George StreetBrisbaneQLD 4000Australia UWA School of Agriculture and Environment The University of Western Australia35 Stirling HighwayCrawleyWA 6009Australia Nepal Agriculture Research Council KhumaltarLalitpurNepal Department of Agronomy University of AgricultureFaisalabad 38040Pakistan Department of Agricultural Botany Dr Panjabrao Deshmukh Krishi VidyapeethAkola 444104MaharashtraIndia ICAR-Indian Institute of Seed Science MauUttar Pradesh 275103India School of Natural Sciences Macquarie UniversityMacquarie ParkNSW 2109Australia ICAR-Indian Institute of Wheat and Barley Research Flowrdale 54642ShimlaIndia International Maize and Wheat Improvement Center(CIMMYT)Bangladesh Office Gulshan-2Dhaka 1212Bangladesh Center for Seed Science University of AgricultureFaisalabad 38000Pakistan Department of Biosciences COMSATS University IslamabadPark RoadTarlai KalanIslamabad 45550Pakistan CgIAR’s Excellence in Breeding(EiB)Platform/Accelerated Breeding Initiative International Maize and Wheat Improvement Center(CIMMYT)El Batán 56237Mexico

Rice and wheat provide nearly 40%of human calorie and protein *** share a common ancestor and belong to the Poaceae(grass)*** their genetic homology is crucial for developing new cultivars with enhanced *** wheat genes and gene families have been characterized based on their rice ***–wheat orthology can identify genetic regions that regulate similar traits in both ***–wheat comparative genomics can identify candidate wheat genes in a genomic region identified by association or QTL mapping,deduce their putative functions and biochemical pathways,and develop molecular markers for marker-assisted breeding.A knowledge of gene homology facilitates the transfer between crops of genes or genomic regions associated with desirable traits by genetic engineering,gene editing,or wide crossing.

关键词： Comparative genomics Orthologs genes Synteny genetic engineering Molecular breeding

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Slip Effects on an Unsteady Boundary Layer Stagnation-Point Flow and Heat Transfer towards a Stretching Sheet

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Chinese Physics Letters 2011年第9期28卷 174-177页

作者： Krishnendu Bhattacharyya swati Mukhopadhyay g.C.Layek Department of Mathematics The University of BurdwanBurdwan-713104West BengalIndia

An analysis is presented for an unsteady boundary layer stagnation-point flow of a Newtonian fluid and the heat transfer towards a stretching sheet taking non-conventional partial slip conditions at the *** self-similar equations are obtained using similarity transformations and solved numerically by the shooting *** of the parameters involved in the equations,especially velocity slip and thermal slip parameters on the velocity and temperature profiles,are analyzed *** is revealed that due to the velocity and thermal slip parameters,the rate of heat transfer from the sheet and the wall skin friction change significantly.

关键词： method stretching unsteady

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MHD Boundary Layer Slip Flow and Heat Transfer over a Flat Plate

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Chinese Physics Letters 2011年第2期28卷 140-143页

作者： Krishnendu Bhattacharyya swati Mukhopadhyay g.C.Layek Department of Mathematics The University of BurdwanBurdwan-713104West BengalIndia

An analysis of magnetohydrodynamic(MHD)boundary layer flow and heat transfer over a flat plate with slip condition at the boundary is presented.A complete self-similar set of equations are obtained from the governing equations using similarity transformations and are solved by a shooting *** the boundary slip condition no local similarity *** and temperature distributions within the boundary layer are *** analysis reveals that the increase of magnetic and slip parameters reduce the boundary layer thickness and also enhance the heat transfer from the plate.

关键词： method boundary similarity

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Inclusion of Finite Permeability on Design and Optimization of an Electromagnetic Undulator

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Chinese Physics Letters 2014年第3期31卷 55-57页

作者： Vijay Huse geetanjali Sharma swati Mishra g. Mishra School of Physics Devi Ahilya University Indore 452001 (M.P.) India

We derive an alternate analytical expression for the optimum dimensions of an electromagnetic undulator with a finite permeability lamination core. The analytical expressions are compared with earlier results under an... 详细信息

关键词： Laminating

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Pathogenesis and clinical spectrum of primary sclerosing cholangitis

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World Journal of gastroenterology 2017年第14期23卷 2459-2469页

作者： Neelam g gidwaney swati Pawa Kiron M Das Division of gastroenterology and Hepatology Rutgers-Robert Wood Johnson Medical School

Primary sclerosing cholangitis(PSC) is a disease of the biliary tract, which has been documented in the literature since 1867. This disease has a strong predilection for affecting men and can be seen in individuals as young as 2 years of age. PSC has a strong associated with inflammatory bowel disease, more commonly with ulcerative colitis, and is also part of the clinical spectrum of Ig g4-related diseases. Smallduct PSC, a variant of PSC, also has an association with inflammatory bowel disease. The exact pathogenesis of PSC is not well understood at present, however, is likely a combination of a genetic predisposition with alteration of the molecular structure of the gut. Abnormal serum liver chemistry and presence of certain autoimmune markers are usually the first indicators leading to a diagnosis of PCS, however, these may often be normal in early stages of this disease. The diagnosis is made by cholangiography, which is now considered the gold standard. PSC is a known pre-malignant condition. Such patients have an increased risk of developing cholangiocarcinoma, gallbladder neoplasia, and colon cancer. Many new treatment modalities have emerged in the recent past, including anti-tumor necrosis factor-α and anti-integrins; however, liver transplantation is the only known cure for PSC. Despite past and present research, PSC remains an enigmatic biliary disease with few viable treatment options.

关键词： Primary sclerosing cholangitis Cholestasis Inflammatory bowel disease Autoimmune gallbladder neoplasia Cholangiocarcinoma Igg4 related disease Colon cancer Liver transplant

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Obesity as potential breast cancer risk factor for postmenopausal women

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genes & Diseases 2021年第2期8卷 117-123页

作者： swati Sucharita Mohanty Prafulla Kumar Mohanty Cytogenetics Laboratory P.G.Department of ZoologyUtkal UniversityBhubaneswar751004OdishaIndia

Breast cancer is the second highest prevalent cancer globally after lung cancer with 2.09 million cases during *** about 1.9 billion were overweight and over 650 million out of these were obese during *** is a significant relationship between breast cancer risk and *** menopause and premenopausal obesity diminish the risk whereas postmenopausal obesity amplifies the risk,because adipose tissue acts as the major reservoir for estrogen biosynthesis after *** estrogen levels in serum along with enhanced peripheral site production of estrogen have been viewed as major reasons of developing breast cancer in overweight postmenopausal *** review explains body fat as a peripheral site for estrogen biosynthesis,estrogen exposure affecting body fat distribution,and the mechanism of estrogen production from body fats.

关键词： Adipocyte Aromatase Breast cancer Estrogen Obesity

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Numerical simulation of physiologically relevant pulsatile flow of blood with shear-rate-dependent viscosity in a stenosed blood vessel

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International Journal of Biomathematics 2018年第6期11卷 129-150页

作者： Subrata Mukhopadhyay Mani Shankar Mandal swati Mukhopadhyay Department of MathematicsAcharya P. C. Roy govt. College Siliguri W.B. India Department of Mathematicsg.g.D. C at Kalna-I Purba Bardhaman-713405 W.B. India Department of MathematicsThe University of Burdwan Burdwan-713104 W.B. India

Pulsatile flow of blood in a blood vessel having time-dependent shape （diameter） is inves-tigated numerically in order to understand some important physiological phenomena in arteries. A smooth axi-symmetric cosine shaped constriction is considered. To mimic the realistic situation as far as possible, viscosity of blood is taken to be non-uniform, a shear-thinning viscosity model is considered and a physiologically relevant pulsatile flow is introduced. Taking advantage of axi-symmetry in the proposed problem, the stream function-vorticity formulation is used to solve the governing equations for blood flow. Effect of different parameters associated with the problem on the flow pattern has been investigated and disparities from the Newtonian case are discussed in detail.

关键词： Pulsatile flow stenosis stream function-vorticity method finite differencete chnique non-Newtonian fluid fluid-structure interaction wall shear stress flow separation.

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Role of hormone receptors and HER2 as prospective molecular markers for breast cancer:An update

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genes & Diseases 2022年第3期9卷 648-658页

作者： swati Sucharita Mohanty Chita Ranjan Sahoo Rabindra Nath Padhy Cytogenetics Laboratory P.G.Department of ZoologyUtkal UniversityBhubaneswarOdisha 751004India Central Research Laboratory Institute of Medical Sciences&SUM HospitalSiksha'O’Anusandhan Deemed to be UniversityBhubaneswarOdisha 751003India

This review provides an updated account on the current methods,principles and mechanism of action of therapies for the detection of molecular markers of therapeutic importance in the prognosis of breast cancer progression and recurrence,which includes estrogen receptor(ER),progesterone receptor(PR)and human epidermal growth factor receptor2(HER2).Indeed,hormone-receptors namely,ER,PR,proto-oncogene HER2 are the basic molecular markers that are recognized and established prognostic factors and predictors of response,for therapeutic *** markers can be detected by using immunohistochemistry(IHC)and fluorescence in situ hybridization(FISH),which are established,faster and cost effective detection *** molecular markers along with clinicopathological prognostic parameters give the best prediction of the prognosis of cancer recurrence and ***,hormone receptors and HER2 as molecular markers are of prime therapeutic importance and have the capability to take part in future drug development techniques.

关键词： Breast cancer Molecular diagnostic Molecular markers Predictive markers Prognostic

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Voltage-controlled NiO/ZnO p–n heterojunction diode: a new approach towards selective VOC sensing

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Microsystems & Nanoengineering 2020年第1期6卷 894-902页

作者： Sayan Dey swati Nag Sumita Santra Samit Kumar Ray Prasanta Kumar guha Department of Electronics&Electrical Communication Engineering Indian Institute of TechnologyKharagpur 721302India Department of Electrical Engineering National Institute of TechnologyAgartala 99046India Department of Physics Indian Institute of TechnologyKharagpur 721302India Department of Physics Belda CollegeBelda 721424India S N Bose National Centre for Basic Sciences Kolkata 700106India

Metal oxide resistive gas sensors suffer from poor selectivity that restricts their practical *** sensor arrays are used to improve selectivity which increased the system ***,we have proposed a novel NiO/ZnO-based p–n junction single-diode device for selective sensing of several volatile organic compounds(VOCs)simultaneously by tuning bias *** operating voltage was varied between 3 and 5 volts to achieve selective sensing of 2-propanol(19.1 times for 95ppm with response and recovery times of 70 s and 55s respectively‚at 3 volts),toluene(20.1 times for 95 ppm with response and recovery times of 100 s and 60 s respectively,at 4 volts),and formaldehyde(11.2 times for 95 ppm with response and recovery times of 88 s and 54s respectively,at 5 volts).A probable mechanism of the tunable selectivity with operating bias voltage due to increase in surface carriers with increasing voltage was hence put ***,this device may play an important role to develop future selective multiple VOC sensor thereby replacing standard sensor arrays.

关键词： selectivity hence thereby

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Phytochemical profiling of Artocarpus lakoocha Roxb. leaf methanol extract and its antioxidant, antimicrobial and antioxidative activities

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Asian Pacific Journal of Tropical Biomedicine 2019年第11期9卷 484-492页

作者： Ekta Bhattacharya Rajashree Dutta swati Chakraborty Suparna Mandal Biswas Agricultural and Ecological Research Unit Indian Statistical Institute203B.T.RoadKolkata 700108India guru Nanak Institute of Pharmaceutical Science&Technology Panihati Kolkata 700114India

Objective:To explore the phytochemical profile of Artocarpus lakoocha *** both qualitatively and quantitatively,and validate its role as a potent antioxidant and antimicrobial ***:Extraction and isolation of different compounds were done from the leaves of Artocarpus lakoocha based on solvent fractionation ***,quantitative and qualitative phytochemical profiling along with antioxidant,antimicrobial and antioxidative activities were tested following standard ***:Among the five fractions,methanol fraction of Artocarpus lakoocha exhibited higher content of phytochemical compounds[phenols=(3175.21±290.43)mg gAE/g dry extract,flavonoids=(1173.15±47.52)mg QE/g dry extract and tannins=(923.53±95.21)mg TAE/g dry extract]as compared to other *** methanol fraction showed the highest antioxidant activity in DPPH and ABTS radical scavenging assays with IC50 of(111.98±34.20)μg/mL and(138.26±0.66)μg/mL,respectively,and the best reduction potential with a value of(316.81±2.96)mg QE/g dry extract in reducing power *** was significant correlation between the amount of phytochemicals and antioxidant ***,the extract successfully protected Lambda phage DNA from damage at 5 and 6 mg/mL concentration and exhibited substantial bactericidal as well as fungicidal *** gC-MS analysis of methanol fraction of Artocarpus lakoocha revealed diethyl phthalate as the main phytochemical compound,along with 3,4-dihydroxymandelic acid,9-octyl eicosane and 7,8-didehydro-3-methoxy-17-methyl-6-methylene ***:The methanol fraction of Artocarpus lakoocha could be used as a potent antioxidant and antimicrobial agent for sustainable agriculture and pharmaceutical purposes.

关键词： Moraceae Bioactive compounds Natural pharmaceuticals Diethyl phthalate

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