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氧化镍和硫化铜矿联合熔炼炉渣的黏度

Transactions of Nonferrous Metals Society of China 2023年第10期33卷 3168-3184页

作者： Alexander KLYUSHNIKOV svetlana sergeeva Roza GULYAEVA Alexander VUSIKHIS Lyudmila UDOEVA Stanislav TYUSHNYAKOV Laboratory of Non-Ferrous Metals Pyrometallurgy Department of Non-Ferrous MetalsInstitute of Metallurgy of the Ural Branch of the Russian Academy of Sciences101Amundsen StreetYekaterinburg 620016Russia Laboratory of Rare Refractory Metals Department of Non-Ferrous MetalsInstitute of Metallurgy of the Ural Branch of the Russian Academy of Sciences101Amundsen StreetYekaterinburg 620016Russia

测定氧化镍和硫化铜矿联合冶炼熔渣的黏度。制备的模拟熔渣与实际熔渣的成分和结构相似,并限制研究的熔渣的成分范围,含铁熔渣的成分(质量分数)为:8.9%CaO、11.8%MgO、12.5%Al_(2)O_(3)、47.4%SiO_(2)、13.3%FeO和5.0%Fe_(2)O_(3);无铁... 详细信息

测定氧化镍和硫化铜矿联合冶炼熔渣的黏度。制备的模拟熔渣与实际熔渣的成分和结构相似,并限制研究的熔渣的成分范围,含铁熔渣的成分(质量分数)为:8.9%CaO、11.8%MgO、12.5%Al_(2)O_(3)、47.4%SiO_(2)、13.3%FeO和5.0%Fe_(2)O_(3);无铁熔渣是将含铁熔渣中的氧化铁去除得到,其成分(质量分数)为:12.5%CaO、16.0%MgO、9.4%Al_(2)O_(3)和58.3%SiO_(2)。由振动法测试的含铁熔渣(1550~1300℃)和无铁熔渣(1550~1400℃)的黏度实验值分别为0.31~2.33 Pa·s和1.28~4.55 Pa·s。由Kalmanovitch-Frank模型预测的含铁熔渣的黏度值与实验值存在偏差。通过Weimann-Frenkel-Urbain方程对实验数据进行回归分析,提出可预测所考虑温度范围内的初级熔渣黏度的原始经验模型。当碱度从0.7(含铁熔渣)降低到0.6(无铁熔渣),黏性流动活化能从204 kJ/mol增加到236kJ/mol。为了保持最佳熔渣黏度,氧化镍和硫化铜矿联合冶炼的温度应不低于1400℃。

关键词：熔渣黏度振动式黏度计 Kalmanovitch–Frank模型 Weimann–Frenkel–Urbain方程氧化镍矿硫化铜矿造锍熔炼

Artrofoon,an oral anti-TNF alpha therapeutic,is effective in both rheumatoid arthritis and osteoarthritis:results of clinical trials

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Artrofoon,an oral anti-TNF alpha therapeutic,is effective in...

超声处理制备大豆油体复合乳液及运载β-胡萝卜素研究

第十五届国际药理学大会

作者： Dugina Mia Martyushev-Poklad Andrey Petrov Vladimir Babayeva Aida Kostryukova Irina Klimenko Karina Kachanova Maria Epstein Oleg sergeeva svetlana Materia Medica Holding 3-rd Samotyochnyi per.9Moscow 127473 Russia Materia Medica Holding 3-rd Samotyochnyi per.9Moscow 127473 Russia Volgograd State Medical University 1Pavshikh BortsovVolgograd 400131 Russia Volgograd State Medical University 1Pavshikh BortsovVolgograd 400131 Russia Volgograd State Medical University 1Pavshikh BortsovVolgograd 400131 Russia Volgograd State Medical University 1Pavshikh BortsovVolgograd 400131 Russia Materia Medica Holding 3-rd Samotyochnyi per. 9Moscow 127473 Russia Materia Medica Holding 3-rd Samotyochnyi per. 9Moscow 127473 Russia Materia Medica Holding 3-rd Samotyochnyi per. 9Moscow 127473 Russia

＜正＞ Recent trials have shown superior efficacy of Artrofoon （anti - TNF alpha antibodies, ultra - low doses for oral use - AF） over diclofenac （DF） in rheumatoid arthritis （RA）. About 57% of patients treated with AF （8 tablets/day） met ACR20 criteria after 6 - month therapy （20% of patients treated with 100 mg of DF daily）. The aim of this study was to test clinical efficacy and safety of AF in osteoarthritis （OA）. In a pilot open - label, comparative trial patients with OA were randomized to receive either AF （8 tablets/day, n = 30） or DF （100 mg/ day,n = 22）. At month 6, total WOMAC （primary endpoint） decreased by 36. 1 and 29.5 points in AF and DF arms *** of WOMAC subscales:pain, stiffness and physical function（secondary endpoints） in AF group improved by 8.4,2.8,and 25.1 points respectively. Although Artrofoon’ s onset of action was slower at month 1, by month 3 the both drugs equalled in efficacy, and at month 6 AF was more effective than the comparator. Unlike DF,AF did not cause drug - related adverse *** is a novel oral anti - TNF - alpha antibody therapeutic that holds great promise both in RA and OA.

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食品工业科技 2024年

作者：王震霄廖一于佳晔齐宝坤王帅 Irina sergeeva 李杨东北农业大学食品学院黑龙江省中蒙俄农产品生物加工及装备研发联合实验室(国际合作)东北农业大学食品学院克麦罗沃国立大学植物基食品技术系

摘要：本研究以大豆油体为原料，将其作为乳化剂，通过超声技术制备大豆油体复合乳液，优化超声处理条件，并将油体复合乳液用于运载脂溶性生物活性物质。通过对乳液的理化性质研究，揭示超声处理增强油体复合乳液

关键词：油体超声运载体 β-胡萝卜素天然乳化剂

Secondary alteration of minerals in basalts of the Evevpenta gold occurrence(North Kamchatka， Russia) as indicators of ore forming processes

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地学前缘 2023年

作者： Anastasiya sergeeva Pavel Zhegunov Elena Skilskaia Mariya Nazarova Elena Kartasheva Anna Kuzmina svetlana Moskaleva Olesya Zobenko Sharapat Kudaeva Ekaterina Plutakhina Kseniya Shishkanova Institute of Volcanology and Seismology， Far Eastern Branch， Russian Academy of Sciences

This paper describes in detail the mineralogy of the propylitic alteration of basalt host rocks in the Evevpenta gold occurrence in North Kamchatka. The vein system of the Evevpenta consists of quartz， adularia-quartz， quartz-carbonate veins， and， hydrothermal breccias hosted in dacite. Vein minerals are native gold， tellurides， sulfides， selenides， Au-Ag chlorides. The propylitic alteration occurs at a distance from the epithermal veins; however， it contains characteristic mineral assemblages useful for the reconstruction of an ore-formation environment. Four distinct hydrothermal alteration assemblages were recognized within the propylitic zone in this study: (1) Fluorapatite-fluorine-aluminous titanite， (2) Quartz-calcite-clinochlore， (3) Quartz-calcite-stilbite-montmorillonite， and 4. Calcite-mordenite. The earliest mineral assemblage was formed from an acid F-enriched hydrothermal fluid. The concentration of fluoride in fluid was 0.2–1.2 g/L， and temperature of about 550 ℃. The long-term interaction between the acid hydrothermal fluid and olivine basalt host rocks resulted in increasing pH to near neutral that caused chloritization process. The chloritization stage hydrothermal fluid was enriched in Fe and Mg with temperatures of about 175–210℃， chlorite I， and 120–140℃， chlorite II. The final stage of alteration consists of zeolite group minerals， which were precipitated from the hydrothermal fluid of pH ～ 9 and temperature >135℃. The high pH of the hydrothermal fluid could be explained by the presence of bicarbonates and carbonates and removal of the iron salt from the solution. Based on the alteration mineral assemblages of the propylitic zone， the physical and chemical conditions of the Evevpenta vein system are discussed. The transport of ore elements took place due to the formation of precious metal Cl–and OH–complexes at the stage of hydrothermal system formation with circulation of alkaline sodium chloride solutions. Chalcogens were also transferred by

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俄罗斯北堪察加Evevpenta金矿床玄武岩矿物次生蚀变特征及其成矿指示作用

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地学前缘 2023年第5期30卷 450-468页

作者： Anastasiya sergeeva Pavel ZHEGUNOV Elena SKILSKAIA Mariya NAZAROVA Elena KARTASHEVA Anna KUZMINA svetlana MOSKALEVA Olesya ZOBENKO Sharapat KUDAEVA Ekaterina PLUTAKHINA Kseniya SHISHKANOVA Institute of Volcanology and Seismology Far Eastern BranchRussian Academy of SciencesPiip Boulevard9Petropavlovsk-Kamchatsky 683006Russia

俄罗斯北堪察加地区Evevpenta金矿床玄武岩主岩青磐岩化蚀变的矿物学组成,是以英安岩中的石英、冰长石-石英、石英-碳酸岩岩脉和热液角砾岩组成的脉系为特征。脉状矿物是天然金、碲化物、硫化物、硒化物和金-银氯化物。青磐岩化蚀变发... 详细信息

俄罗斯北堪察加地区Evevpenta金矿床玄武岩主岩青磐岩化蚀变的矿物学组成,是以英安岩中的石英、冰长石-石英、石英-碳酸岩岩脉和热液角砾岩组成的脉系为特征。脉状矿物是天然金、碲化物、硫化物、硒化物和金-银氯化物。青磐岩化蚀变发生在距浅成热液脉较远的地方。然而,它的特征矿物组合对重建成矿环境有重要研究意义。在青磐岩化带内可识别出氟磷灰石-氟铝钛矿、石英-方解石-斜绿泥石、石英-方解石-硬石-蒙脱石、方解石-丝光沸石4种不同的热液蚀变组合。最早的矿物组合形成于酸性富F的热液中。热液流体中氟化物浓度为0.2~1.2 g/L,流体温度约550℃。酸性热液与橄榄玄武岩寄主岩石长期相互作用,导致pH升高至接近中性并发生绿泥石化作用。绿泥石化阶段热液富集Fe和Mg,温度约175~210℃时形成第1阶段绿泥石,120~140℃时形成第2阶段绿泥石。蚀变的最后阶段形成沸石群矿物,其在pH约为9、温度>135℃的热液中析出。热液流体的高pH值可能是由于碳酸氢盐和碳酸盐的存在以及溶液中铁盐的去除。根据青磐岩化带蚀变矿物组合特征,探讨了Evevpenta脉系形成的物理化学条件。在热液体系形成阶段,随着碱性氯化钠溶液的循环,贵金属Cl~-和OH~-络合物的形成导致了矿石元素的运移。高pH溶液也能转移硫。

关键词：矿物学金丝光沸石斜绿泥石青磐岩化蚀变 Evevpenta 堪察加

The Extent and Effectiveness of Protected Areas in the Russian Federation

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Journal of Geodesy and Geoinformation Science 2022年第2期5卷 75-84页

作者： Kseniia sergeeva Hui LIN School of Geography and Environment/UNESCO HIST-NB Jiangxi Normal UniversityNanchang 330022China Key Laboratory of Poyang Lake Wetland and Watershed research Ministry of Education Nanchang 330022China

To tackle environmental challenges and in particular,the problems associated with the high demand for forests and resources,the consequence of which is the degradation of ecological systems,Russia has developed the biggest network of specially protected natural areas in the *** the scale of SPNA may look impressive,a recent comprehensive study of the period from 2001 to 2018 brought the spotlight on protected areas in Russia experiencing significant tree loss *** Russia is confronting unprecedented fires that break records every year,the problem of preserving rare animal and plant species,their habitats,and natural ecosystems is *** paper is intended to assess the extent and effectiveness of SPNAs with regard to wilderness conservation in the Russian Federation based on the latest data;the main focus being on the period of 2014—2019,before and after the launch of the environmental safety strategies,along with additional analysis of available data for the following year of *** due consideration of unique geographical,economic,and socio-cultural circumstances,as well as historical background and legislative reality of SPNAs in Russia,we have conducted a statistical analysis of data from the official annual reports from the Federal State Statistics Service on SPNAs by territories and significance,expenditures on maintenance and ecotourism,followed by RGB analysis of satellite imagery via means of GIS software for visualization of obtained data and further *** the growth of the SPNA network in Russia,resulting in an astonishing 2402 Mha in 2020,an estimated 4 Mha of tree loss accounted for SPNAs over the period of 2014—2019,and 134 Mha in 2020 *** findings indicate a need for the application of a comprehensive GIS approach for further development and effective management of the SPNA network in ***,the results include recommendations on legislative changes,engagement of locals in SPNA protection,and po

关键词： GIS remote sensing protected area SPNA nature conservation deforestation tree loss

miR 204-5p inhibits apoptosis in dacarbazine-treated melanoma cells

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Oncology Research 2021年第6期29卷 393-400页

作者： NADEZHDA PALKINA EKATERINA sergeeva TATIANA RUKSHA Krasnoyarsk State Medical University Krasnoyarsk660022Russian Federation

Melanoma is one of the most aggressive types of malignant tumors,commonly affecting young *** treatment of metastatic tumors remains obscure due to the resistance of tumor cells to drugs mediated by various *** acquisition of a resistant phenotype is associated with both genetic and epigenetic alterations in cancer ***,the current study aimed to investigate whether microRNA(miR)-204-5p could promote alterations in the cell cycle and apoptosis of dacarbazine(DTIC)-treated melanoma *** real time PCR showed that transfection of DTIC-treated SK-MEL-2 melanoma cells with miR-204-5p mimics signiﬁcantly upregulated ***,ﬂow cytometric analysis revealed that the proportion of cells in different phases of the cell cycle remained ***,the proportion of early apoptotic cells was notably enhanced following cell treatment with DTIC,accompanied by a profound increase in Ki-67 negative cells,as veriﬁed by an immunoﬂuorescence ***,miR-204-5p overexpression reduced the percentage of early apoptotic DTIC-treated melanoma *** proportion of Ki-67 negative cells was only increased by 3%.Overall,the results of the current study indicated that miR-204-5p overexpression could mostly attenuate cell apoptosis in DTIC-treated cells rather than promote their transition from the G0 phase of the cell cycle in response to chemotherapeutic agent-induced stress.

关键词： Cell cycle senescence Ki-67 microRNA

Natural variation of hormone levels in Arabidopsis roots and correlations with complex root architecture

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Journal of Integrative Plant Biology 2018年第4期60卷 292-309页

作者： Sangseok Lee Lidiya l.sergeeva Dick Vreugdenhil Laboratory of Plant Physiology Wageningen University&ResearchDroevendaalsesteeg 16708 PBWageningenThe Netherlands Gyeongsangbuk-Do Agricultural Research&Extension Services Centre 136 Gil-14Chilgokjungang-daeroDaeguSouth Korea

Studies on natural variation are an important tool to unravel the genetic basis of quantitative traits in plants. Despite the significant roles of phytohormones in plant development, including root architecture, hardly any studies have been done to investigate natural variation in endogenous hormone levels in plants. Therefore, in the present study a range of hormones were quantified in root extracts of thirteen Arabidopsis thaliana accessions using a ultra performance liquid chromatography triple quadrupole mass spectrometer. Root system architecture of the set of accessions was quantified, using a new parameter （mature root unit） for complex root systems, and correlated with the phytohormone data. Significant variations in phytohormone levels among the accessions were detected, but were remarkably small, namely less than three-fold difference between extremes. For cytokinins, relatively larger variations were found for ribosides and glucosides, as compared to the free bases. For root phenotyping, length-related traits--lateral root length and total root length--showed larger variations than lateral root number-related ones. For root architecture, antagonistic interactions between hormones, for example, indole-3-acetic acid to trans-zeatin were detected in correlation analysis. These findings provide conclusive evidence for the presence of natural variation in phytohormone levels in Arabidopsis roots, suggesting that quantitative genetic analyses are feasible.

关键词： Natural variation of hormone levels in Arabidopsis roots and correlations with complex root architecture

Magnetic field hyperactivity during the early Neoproterozoic: A paleomagnetic and cyclostratigraphic study of the Katav Formation, southern Urals, Russia

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Geoscience Frontiers 2023年第4期14卷 42-56页

作者： Inessa V.Golovanova Konstantin N.Danukalov Raushaniia Yu.Salmanova Natalia M.Levashova Nikita P.Parfiriev Nina D.sergeeva Joseph G.Meert Institute of Geology-Subdivision of the Ufa Federal Research Centre of the Russian Academy of Sciences(IG UFRC RAS) Russia Geological Institute Russian Academy of SciencesMoscowRussia Department of Earth and Planetary Sciences Neil Opdyke Paleomagnetic LaboratoryUniversity of FloridaGainesvilleFL 32611United States

We present a detailed magnetostratigraphic and cyclostratigraphic profile through the Riphean(Tonian)Katav Formation in the southern *** study confirms the primary nature of the magnetization in these *** cyclostratigraphic study identified several orbital periods including the 405 ka long *** allows us to quantify the reversal frequency in the Katav and our estimates range of 7–12 reversals per million *** on our study,we identify an interval of magnetic field reversal hyperactivity in the Neoproterozoic *** estimates for the Katav are contentious and range somewhere between 800 Ma and 900 Ma based on carbonate Pb-Pb ages and stable isotope *** paleomagnetic poles obtained in this study of the Katav(and overlying Inzer)Formation do not fit anywhere on the Baltica apparent polar wander path between 1100 Ma and 900 ***,they lie 90away from the 900 Ma segment of the *** tentatively estimate their age to be closer to 800 Ma and perhaps confirm a previously hypothesized pulse of rapid true polar wander between 825 Ma and 790 Ma.

关键词： Magnetostratigraphy Cyclostratigraphy Hyperactive reversal True polar wander Tonian