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Advanced imaging and visualization in gastrointestinal disorders

World Journal of Gastroenterology 2007年第9期13卷 1408-1421页

作者： Odd Helge Gilja Jan G Hatlebakk svein φdegaard Arnold Berstad Ivan Viola Christopher Giertsen Trygve Hausken Hans Gregersen National Centre for Ultrasound in Gastroenterology Department of Medicine Haukeland University HospitalNorwayInstitute of Medicine3Institute of Informatics University of Bergen Bergen Norway Institute of Medicine 3Institute of Informatics University of Bergen Bergen Norway National Centre for Ultrasound in Gastroenterology Department of Medicine Haukeland University HospitalNorwayInstitute of Medicine3Institute of Informatics University of Bergen Bergen Norway Institute of Informatics University of BergenBergenNorway Christian michelsen Research AS Bergen Norway National Centre for Ultrasound in Gastroenterology Department of Medicine Haukeland University HospitalNorwayInstitute of Medicine3Institute of Informatics University of Bergen Bergen Norway Institute of Medicine 3Institute of Informatics University of BergenBergen NorwayCenter foe Visceral Biomechanics and PainAalborg Hospital and Center for Sensory-motor InteractionAalborg universityDenmark

Advanced medical imaging and visualization has a strong impact on research and clinical decision making in gastroenterology. The aim of this paper is to show how imaging and visualization can disclose structural and functional abnormalities of the gastrointestinal (GI) tract. Imaging methods such as ultrasonography, magnetic resonance imaging (MRI), endoscopy, endosonography, and elastography will be outlined and visualization with Virtual Reality and haptic methods. Ultrasonography is a versatile method that can be used to evaluate antral contractility, gastric emptying, transpyloric flow, gastric configuration, intragastric distribution of meals, gastric accommodation and strain measurement of the gastric wall. Advanced methods for endoscopic ultrasound, three-dimensional (3D) ultrasound, and tissue Doppler (Strain Rate Imaging) provide detailed information of the GI tract. Food hypersensitivity reactions including gastrointestinal reactions due to food allergy can be visualized by ultrasonography and MRI. Development of multi-parametric and multi-modal imaging may increase diagnostic benefits and facilitate fusion of diagnostic and therapeutic imaging in the future.

关键词： Ultrasonography Medical imaging Functional imaging Elasticity

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Gastric emptying measured by ultrasonography

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World Journal of Gastroenterology 1999年第2期5卷 5-6页

作者： Odd Helge Gilja, Trygve Hausken, svein degaard and Arnold Berstad

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Ａｎｕｍｂｅｒｏｆｄｉｆｆｅｒｅｎｔｍｅｔｈｏｄｓｈａｖｅｂｅｅｎｕｓｅｄｔｏｅｓｔｉｍａｔｅｇａｓｔｒｉｃｅｍｐｔｙｉｎｇｉｎｈｕｍａｎｓ，ａｎｄａｌｈａｖｅｔｈｅｉｒａｄｖａｎｔａｇｅｓａｎｄｄｉｓａｄｖａｎｔａｇｅｓ．Ｔｈｅｍｅｔｈｏｄｏｆｃｈ...

关键词： gastric emptying stomach/ultrasonography stomach/pathophysiology

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Sonography of the small intestine

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World Journal of Gastroenterology 2009年第11期15卷 1319-1330页

作者： Kim Nylund svein фdegaard Trygve Hausken Geir Folvik Gülen Arslan Lied Ivan Viola Helwig Hauser Odd-Helge Gilja National Centre for Ultrasound in Gastroenterology Department of Medicine Haukeland University Hospital 5021 Bergen Norway Odd-Helge Gilja Institute of Medicine University of Bergen 5021 Bergen Norway Department of Medicine Haukeland University Hospital 5021 Bergen Norway Institute of Informatics University of Bergen 5008 Bergen Norway

In the last two decades, there has been substantial development in the diagnostic possibilities for examining the small intestine. Compared with computerized tomography, magnetic resonance imaging, capsule endoscopy and double-balloon endoscopy, ultrasonography has the advantage of being cheap, portable, flexible and user-and patient-friendly, while at the same time providing the clinician with image data of high temporal and spatial resolution. The method has limitations with penetration in obesity and with intestinal air impairing image quality. The flexibility ultrasonography offers the examiner also implies that a systematic approach during scanning is needed. This paper reviews the basic scanning techniques and new modalities such as contrast-enhanced ultrasound, elastography, strain rate imaging, hydrosonography, allergosonography, endoscopic sonography and nutritional imaging, and the literature on disease-specific findings in the small intestine. Some of these methods have shown clinical benefit, while others are under research and development to establish their role in the diagnostic repertoire. However, along with improved overall image quality of new ultrasound scanners, these methodshave enabled more anatomical and physiological changes in the small intestine to be observed. Accordingly, ultrasound of the small intestine is an attractive clinical tool to study patients with a range of diseases.

关键词： Contrast-enhanced ultrasound Crohn'sdisease Endoscopic sonography Endosonography Enteroclysis Hydrosonography Magnetic resonanceimaging Ultrasonography Virtual endoscopy Visualization

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Liver segment 2+3 living donation in liver transplantation for colorectal liver metastases

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Hepatobiliary Surgery and Nutrition 2020年第3期9卷 382-384页

作者： svein Dueland Pal-Dag Line Department of Oncology Oslo University HospitalOsloNorway Department of Transplantation Medicine Oslo University HospitalOsloNorway and Institute of Clinical MedicineUniversity of OsloNorway

Liver transplantation(LT)was offered to some colorectal cancer(CRC)patients with liver only metastases in the 1990s,however the treatment option was discontinued due to poor overall survival(OS)of 43%at 2 years posttr... 详细信息

关键词： colorectal metastases Liver

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Morphology and motor function of the gastrointestinal tract examined with endosonography

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World Journal of Gastroenterology 2006年第18期12卷 2858-2863页

作者： svein Odegaard Lars Birger Nesje Dag Arne Lihaug Hoff Odd Helge Gilja Hans Gregersen National Centre for Ultrasound in Gastroenterology Department of MedicineHaukeland University HospitalBergenNorway Institute of MedicineUniversity of BergenBergenNorway Institute of Medicine University of BergenBergenNorway Department of MedicineAalesund HospitalAalesundNorway Institute of Medicine University of BergenBergenNorway Centre for Visceral Biomechanics and PainAalborg HospitalSMIAalborg UniversityAalborgDenmark

Endosonography is a useful tool for studying the morphology and motor function of the gastrointestinal tract. Intraluminal ultrasonography is the common denomination of ultrasound examinations using intracorporal transducers which are inserted into the GI tract. Thus, the visceral wall and adjacent structures can be imaged in detail. This review describes the usefulness of endosonography in gastroenterology, in particular with respect to studies of the biomechanical and motor function of the gastrointestinal tract. New techniques such as 3-D EUS, elastography and strain rate imaging are discussed.

关键词： Intraluminal ultrasonography Gastrointestinal tract Imaging Biomechancs

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Simplified Approximate Expressions for the Boundary Layer Flow in Cylindrical Sections in Plankton Nets and Trawls

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Open Journal of Marine Science 2012年第2期2卷 66-69页

作者： svein Helge Gjosund SINTEF Fisheries and Aquaculture TrondheimNorway

Trawls and plankton nets are basically made up of conical and cylindrical net sections. In conical sections the flow will pass through the inclined net wall with a noticeable angle of attack, and then the flow, filtration and drag can be suitably modelled e.g. by a pressure drop approach [1]. In cylindrical and other non-tapered net sections, such as foreparts and extension pieces in trawls and plankton nets, the flow is directed along the net wall and is best considered in terms of a boundary layer. Boundary layer theory and turbulence models can be used to describe such flow, but this requires extensive numerical modelling and computational effort. Simplified approximate formulas providing a qualitative description of the flow with some quantitative accuracy are therefore also useful. This work presents simplified parametric expressions for boundary layer flow in cylindrical net sections, including the boundary layer thickness and growth rate along the net, the filtration velocity out of the net wall, the decrease in mass flux through the net due to the growing boundary layer, and the effect of twine thickness, flow (towing) velocity and the dimensions of the net. These expressions may be useful for assessing the existence and extension of a boundary layer, for appropriate scaling of boundary layer effects in model tests, for proper placement of velocity measurement probes, for assessing the influence on filtration and clogging of plankton net sections, and more.

关键词： Plankton Nets Trawls Non-Tapered Sections Flow Boundary Layer Filtration Drag

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北欧国家的环境和自然资源统计

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中国统计 2005年第2期20卷 53-54页

作者： svein Homstvedt 胡卫挪威统计局环境统计处国家统计局办公室

在和挪威统计局四年合作的过程中,我们和挪威同事建立了非常深厚的友谊,时至今日我们仍经常有业务上的交流。这篇文章对于我们系统内刚刚起步的环境统计来说,可能会有些帮助和启示,故将其翻译成中文,并经原作者同意后登出。

关键词：北欧环境统计自然资源统计

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To Die at Home or to End Life in an Institution

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Open Journal of Nursing 2015年第6期5卷 538-547页

作者： Liv Wergeland Sorbye Simen A.Steindal svein Lyngroth Institute of Nursing and Health Diakonhjemmet University CollegeOsloNorway Palliative Care Unit Department of OncologyOslo University HospitalOsloNorway Agenda Kaupang Evaluation&AssessmentB■rumNorway

In the Western world, 60%-80% of all deaths occur in an institution. This study aimed to determine the main causes for the low proportion of deaths at home in Norway. A retrospective cohort study was conducted in six Norwegian municipalities. The study employed official statistics and structured interviews with key staff individuals (spring 2012). We included 41 individuals that received palliative home care;21 died at home. The rate of deaths at home may be increased by an acceptance of death and confidence that home is a good, safe place to die. This study showed how challenging it was for the family and health personnel to be a fellow Pellegrino in the last steps of life. However, when physical distress is under control, and when a dying patient and his significant other genuinely wish for death at home, it is necessary to control physical distress. Greater holistic well-being may then be achieved at home than in the hospital.

关键词： Home Care Services Attitude towards Death Retrospective Cohort Studyomponent

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主动脉瓣口血流速度空间分布形成机理研究

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中国超声医学杂志 1999年第12期15卷 3-5页

作者：周玉清,svein Faerestrand,张青萍,乐桂蓉武汉市同济医科大学附属同济医院超声科 Dept.HeartDisease HaukelandHospital UniversityofBergen Norway 武汉市同济医科大学附属同济医院超声科武汉市同济医科大学附属同济医院超声科

目的：通过动物试验探讨主动脉瓣口血流速度空间分布的形成机理。方法：研究对象包括１０只猪，在全麻下实施开胸手术暴露心脏，并获得左室流出道长轴切面，使其长轴平行于超声声束方向。研究内容包括：１）利用彩色多普勒血流... 详细信息

目的：通过动物试验探讨主动脉瓣口血流速度空间分布的形成机理。方法：研究对象包括１０只猪，在全麻下实施开胸手术暴露心脏，并获得左室流出道长轴切面，使其长轴平行于超声声束方向。研究内容包括：１）利用彩色多普勒血流成像测量主动脉瓣口血流速度空间分布扭曲程度；２）观察左室流出道中轴线两侧彩色血流的对称性，判断血流会聚状态；３）根据二维图像测量室间隔角度。然后观察在整个射血期内上述三个指标的动态变化。结果：主动脉瓣口血流速度空间分布状态随左室流出道内血流会聚方式变化而变化。在射血早期，左室流出道内血流会聚方式最不对称，大部分血流沿室间隔及左室前壁流向主动脉瓣口。相应地，主动脉瓣口血流速度分布的扭曲程度最大，且最大流速紧靠室间隔及左室前壁。射血中、晚期，左室流出道内血流逐渐变为呈中轴对称性地进入主动脉瓣口，此时主动脉瓣口血流速度分布变为平坦对称。然而，从左室射血早期到中、晚期，室间隔角度却逐渐增大。结论：左室流出道内的血流会聚方式是决定主动脉瓣口血流速度空间分布的最重要因素。

关键词：血流速度分布彩色多普勒血流图主动脉瓣口左室流出道

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Fatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients

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World Journal of Gastroenterology 2018年第29期24卷 3293-3301页

作者： svein Oskar Frigstad Marte Lie Hoivik Jorgen Jahnsen Milada Cvancarova Tore Grimstad Ingrid Prytz Berset Gert Huppertz-Hauss Oistein Hovde Tomm Bernklev Bjorn Moum Lars-Petter Jelsness-Jorgensen Department of Medicine Vestre Viken Baeum HospitalGjettum 1346Norway Department of Gastroenterology Ostfold Hospital KalnesGralum 1714Norway Department of Health Sciences Ostfold University CollegeHalden 1757Norway Department of Gastroenterology Stavanger University HospitalStavanger 4068Norway Department of Research Otfold Hospital KalnesGralum 1714Norway Department of Gastroenterology Oslo University HospitalOslo 0424Norway Department of Gastroenterology Akershus University HospitalLorenskog 1478Norway Faculty of Health Sciences Oslo Metropolitan UniversityOslo 0130Norway Department of Medicine Alesund Hospital TrustAlesund 6026Norway Department of Gastroenterology Telemark Hospital TrustSkien 3710Norway Department of Medicine Innlandet Hospital TrustGjovik 2819Norway Department of Research and Development Vestfold Hospital TrustTonsberg 3103Norway

AIM To investigate if vitamin D deficiency is associated with fatigue in patients with inflammatory bowel disease(IBD).METHODS IBD patients were recruited from nine hospitals in the southeastern and western regions of Norway to participate in a multicenter cross-sectional study lasting from March 2013 to April 2014. Data were collected by interviews, from medical records and laboratory tests. The Fatigue Questionnaire(FQ) was used to measure fatigue. Linear and logistic regression models were applied to explore the possible association between vitamin D deficiency and total fatigue scores and chronic fatigue, respectively. The analyses were adjusted for age, gender, disease activity, depressive symptoms and sleep *** In total, 405 patients were included in the analyses, of which 227(56%) had Crohn's disease(CD) and 178(44%) had ulcerative colitis(UC). Vitamin D deficiency(< 50 nmol/L) was present in half(203/405) of the patients. Chronic fatigue was reported by 116(29%) of all included patients with substantial fatigue reported by 194(48%). Vitamin D levels were neither associated with total fatigue nor with chronic fatigue. Higher total fatigue scores and chronic fatigue were both associated with increased disease activity scores in patients with UC and CD, but not with increased CRP or fecal calprotectin. In UC patients, female gender was associated with fatigue in the univariate analysis, but no such difference was found when adjusted for elevated disease activity scores. Sleep disturbance and more depressive symptoms were associated with total fatigue scores in both UC and CD patients, but with chronic fatigue only in CD *** In this study, no significant association between fatigue and vitamin D deficiency in IBD patients was revealed.

关键词： Inflammatory bowel disease Crohn's disease Ulcerative colitis Fatigue Chronic fatigue Vitamin D deficiency

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