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The technological potential of agro-industrial residue from grape pulping(Vitis spp.)for application in meat products:A review

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Food Bioscience 2022年第5期49卷 40-49页

作者： Marcelo Edvan dos Santos silva Cristiani Viegas Brand˜ao Grisi suzana pedroza da silva Marta Suely Madruga F´abio Anderson Pereira da silva Post-Graduate Program in Food Science and Technology Department of Food EngineeringTechnology CentreFederal University of ParaibaJo˜ao PessoaParaiba58051-900Brazil Post-Graduate Program in Agrifood Technology Federal University of ParaibaCampus Universitario IIIBananeirasPBBrazil Federal University of Pernambuco’s Agreste Av.Bom PastorBoa Vista55296-901GaranhunsPEBrazil

This review aimed to investigate the technological potential of grape pomace for application in the meat industry,approaching the compounds of interest and presenting the challenges of its application in meat *** pomace contains bioactive and nutritional compounds with beneficial properties for maintaining the physical-chemical,sensory,and nutritional quality of meat and its *** studies have reported the presence of fiber,amino acids,essential fatty acids and minerals capable of increasing the nutritional value of meat products and promoting a nutrient supply when associated with animal ***,the bioactive composition of grape pomace has anthocyanins,flavanols and phenolic acids capable of increasing the shelf life of meat products,inhibiting microbial development,and delaying the oxidative processes responsible for the deterioration of sensory and nutritional *** use of nano and microencapsulation technologies and the use of active packaging as carriers of grape pomace extracts enhance their application in meat and meat *** technologies,applied individually or together,promote the controlled release of bioactive compounds during the storage and mask undesirable flavors promoted by phenolic *** addition to the technological potential,the use of grape pomace by the meat industry meets the current demand for the use of natural additives and is in accordance with the sustainable development objectives established by the United Nations Organization,reducing environmental impacts and allowing the obtaining molecules with high added value from industrial waste.

关键词： Natural antioxidant Grape bagasse Meat products Bioactive compounds Oxidation Waste reuse

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Microencapsulated phenolic-rich extract from juice processing grape pomace(Vitis *** Var):Effects on oxidative stability of raw and pre-cooked bovine burger

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Food Bioscience 2022年第6期50卷 2120-2129页

作者： Marcelo Edvan dos Santos silva Rodrigo Lira de Oliveira Thamyres Cesar de Albuquerque Sousa Cristiani Viegas Brandão Grisi Valquíria Cardoso da silva Ferreira Tatiana Souza Porto Marta Suely Madruga suzana pedroza da silva Fábio Anderson Pereira da silva Post-Graduate Program in Food Science and Technology Department of Food EngineeringTechnology CentreFederal University of ParaibaJoão PessoaParaiba58051-900Brazil Northeast Biotechnology Network/RENORBIO Federal Rural University of Pernambuco (UFRPE)Dom Manoel de MedeirosDois Irmãos52171-900RecifePEBrazil Federal University of Pernambuco's Agreste (UFAPE) GaranhunsAv.Bom PastorBoa Vista55296-901 GaranhunsPEBrazil Post-Graduate Program in Agrifood Technology Federal University of ParaibaCampus Universitario IIIBananeirasPBBrazil

Grape processing generates residues rich in bioactive compounds with potential application in the meat ***,these substances are unstable and needs to be treated to allow their action during the processing and storage of meat *** this sense,a phenolic-rich extract from grape pomace was microencapsulated and evaluated for its potential to inhibit the oxidative process in raw and precooked beef burgers during cold *** hamburger formulations containing lyophilized extract(LEB),microencapsulated extract(MEB)and synthetic antioxidant sodium erythorbate(SEB)were prepared,pre-cooked,and evaluated for lipid and protein *** microencapsulation,with 95.0%efficiency,provided a material with a crystalline structure,rich in phenolics and with high antioxidant potential,showing 377.4±0.01,1768.1±0.07 and 1185.0±0.20μmol TEAC.100 g−1 for DPPH,ABTS and FRAP,*** values of malonaldehyde were found in LEB and MEB(2.9±0.3 and 1.4±0.5 mg ***−1,respectively)at the end of storage,with emphasis on for the hamburgers that received the microencapsulated *** behavior was observed for the analysis of carbonyl compounds,with values of 11.1±1.1,8.7±1.4 and 6.8±1.0 nM ***−1 in SEB,LEB and MEB,***,the freeze-dried and microencapsulated grape extracts showed superior results when compared to the synthetic antioxidant,increasing the oxidative stability of hamburgers,and avoiding significant color changes during the cold *** results indicate the high potential of the microencapsulated material to be used as a natural antioxidant in the meat industry.

关键词： Lipid oxidation Protein oxidation Meat products Natural antioxidant Encapsulation

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Non-Polar Chemical Constituents of Atemoya and Evaluation of the Cytotoxic and Antimicrobial Activity

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Phyton-International Journal of Experimental Botany 2021年第3期90卷 921-931页

作者： suzana Vieira Rabêlo Fernanda Granja da silva Oliveira Michele Miriam Calixto de Lira Livia Macedo Dutra Adilson Sartoratto Marta Cristina Teixeira Duarte Maria Claudia dos Santos Luciano Maria Francilene Souza silva Cláudia doÓPessoa Manoel Odorico de Moraes Filho Emmanoel Vilaça Costa Jackson Roberto Guedes da silva Almeida Post-Graduate Program in Biotechnology(RENORBIO) Federal Rural University of PernambucoRecifePernambuco52171-900Brazil Post-Graduate Program in Biotechnology State University of Feira de SantanaFeira de SantanaBahia44036-900Brazil Center for Studies and Research of Medicinal Plants(NEPLAME) Federal University of San Francisco ValleyPetrolinaPernambuco56304-205Brazil Multidisciplinary Center of Chemical Biological and Agricultural Research(CPQBA)Campinas State UniversityCampinasSão Paulo13083-970Brazil National Laboratory of Experimental Oncology(LabNOE) Federal University of CearáFortalezaCeará60020-181Brazil Departament of Chemistry Federal University of AmazonasManausAmazonas69067-005Brazil

This study aimed to identify the chemical composition of essential oil from fruits(EOAF)and the hexanic crude extract from aerial parts(At-Hex)of atemoya(Annona cherimola x Annona squamosa),a hybrid belonging to the Annonaceae *** and antimicrobial activity was also *** was obtained by hydrodistillation using a Clevenger apparatus,and their composition was analyzed by gas chromatography-mass spectrometry(GC-MS)*** was tested against human tumor cell lines HCT-116(colon carcinoma),SF-295(glioblastoma),OVCAR-8(ovarian carcinoma)and HL60(leukemia)using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide(MTT)assay,while antimicrobial activity was conducted by bioauthography method against eleven microorganisms ***-four compounds were identified in the EOAF and twenty-nine in *** monoterpenes linalool(25.70%),α-pinene(10.38%),β-pinene(9.12%),transocimene(7.43%),and the sesquiterpene bicyclogermacrene(12.58%)were the major constituents of EOAF,whereas the sesquiterpene spathulenol(13.91%)was the main compound of ***-Hex showed a high cytotoxicity against SF-295(glioblastoma).These findings show an important chemotaxonomic contribution for the Annonaceae family,mainly for the Annona *** proved to be a promising source of substances with potential cytotoxic activity.

关键词： Annona GC-MS volatile compounds terpenoids biologic activities

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FTIR Characterization of Gelatin from Chicken Feet

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Journal of Chemistry and Chemical Engineering 2012年第11期6卷 1029-1032页

作者： Poliana Fernandes de Almeida suzana Caetano da silva Lannes Felipe Araujo Calarge Thiago Michel de Brito Farias Jose Carlos Curvelo Santana Federal Institute of Education ofMato Grosso Sao Vicente Campus Cuiaba 78106-000 Brazil Faculty of Pharmaceutical Sciences University of Sao Paulo Sao Paulo 05508-000 Brazil Laboratory of Biotechnology and Quality Control Nove de Julho University Sao Paulo 05001-100 Brazil

The objective of this study was characterizing the gelatin from the chicken feet by FTIR （Fourier transform infrared） spectroscopy. Two gelatin samples were prepared for the experiment which were extracted of 200 g of chicken feet by a thermal bath of 4% acetyl acid solution at 60 ℃. A commercial gelatin was used to compare the results. FTIR spectra of gelatin samples were recorded using a Nicolet iS5 FTIR spectrometer equipped with an ATR/iD3 with argon horizontal cell in which the spectra were varied in the range of 400-4,000 cm1 at 16 ~C. The results showed that FTIR spectra of the chicken feet gelatin had the most with the vibration peak at wave numbers of 1,652.01 cm~ to the amide I, of 1,539.87 cm1 to the amide II, of 1,241.29 cm~ to the amide III, of 2,923.72 cm-~ to the amide B and of 3,399.56 cm~ to the amide A. The collagen composition of the chicken feet gelatins was twotimes larger than the commercial gelatin and the vibration bands to beef gelatin have been different from chicken feet gelatins. This demonstrates that chicken feet gelatins are very good nutritional quality when compared to the commercial gelatin.

关键词： FTIR gelatin chicken feet collagen composition.

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Differences in age modulates neutrophils function

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Advances in Biological Chemistry 2014年第1期4卷 51-58页

作者： Claudia J. Lagranha Tatiana C. Alba-Loureiro Aline Isabel da silva danuta Duarte Bezerra de Lima Anderson Apolonio pedroza Diorginis Ferreira Tania Pithon-Curi Department of Nutrition Federal University of Pernambuco Recife Brazil Department of Physical Education and Sports Science Federal University of Pernambuco Vitoria de Santo Ant&atilde o Brazil Department of Physiology and Biophysics Institute of Biomedical Sciences University of S&atilde o Paulo S&atilde o Paulo Brazil Post-Graduate Program in Human Movement Science Biological Sciences and Health Center Cruzeiro do Sul University Sao Paulo Brazil

The sexual maturation in all mammals is the period in which the quiescent gonads are activated by gonadotropins from anterior pituitary, increasing the secretion of sexual hormones. Sexual maturation it is also related with the development of several other body features such as body mass and maturation of the circulatory, skeletal and hematopoietic systems. The aim of the present study was to evaluate the function of neutrophils submitted to in vivo lower and higher concentration of testosterone (sexually immature: 60 days and sexually mature: 90 days). Using different approaches we evaluated cell viability and function and gene expression in rat neutrophils from 60 and 90 days-old animals. Neutrophils from 90 days-old rats showed a decrease in phagocytic and fungicidal capacity, without change in cellular viability. Additionally, we verified that sexual maturation induced increase in production of reactive oxygen and nitrogen species (RONS) and also in TNF-α, IL-6 and IL-10 cytokines. In conclusion, our data suggest that increase in testosterone levels induced significant alteration in neutrophil function, impairing phagocytic capacity.

关键词： Testosterone Neutrophils Function NADPH-Oxidase Components Sexual Maturation

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Grade 4 febrile neutropenia and Fournier's Syndrome associated with triple therapy for hepatitis C virus:A case report

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World Journal of Hepatology 2014年第6期6卷 448-452页

作者： Kelly Cristhian Lima Oliveira Emili de Oliveira Bortolon Cardoso suzana Carla Pereira de Souza Flávia Souza Machado Carlos Eduardo Alves Zangirolami Alecsro Moreira Giovanni Faria silva Cássio Vieira de Oliveira Division of Gastroenterology Department of Internal MedicineBotucatu School of Medicine18618-970 Sao PauloBrazil

The use of triple therapy for hepatitis C not only increases the rate of sustained virological responses compared with the use of only interferon and ribavirin(RBV) but also leads to an increased number of side effects. The subject of this study was a 53-year-old male who was cirrhotic with hepatitis C virus genotype 1 A and was a previous null non-responder. We initially attempted retreatment with boceprevir(BOC), Peginterferon and RBV, and a decrease in viral load was observed in the 8th week. In week 12, he presented with disorientation, flapping, fever, tachypnea, arterial hypotension and tachycardia. He also exhibitedleucopenia with neutropenia. Cefepime and filgrastim were initiated, and treatment for hepatitis C was suspended. A myelogram revealed hypoplasia, cytotoxicity and maturational retardation. After 48 h, he developed bilateral inguinal erythema that evolved throughout the perineal area to the root of the thighs, with exulcerations and an outflow of seropurulent secretions. Because we hypothesized that he was suffering from Fournier's Syndrome, treatment was replaced with the antibiotics imipenem, linezolid and clindamycin. After this new treatment paradigm was initiated, his lesions regressed without requiring surgical debridement. Triple therapy requires knowledge regarding the management of adverse effects and drug interactions; it also requires an understanding of the importance of respecting the guidelines for the withdrawal of treatment. In this case report, we observed an adverse event that had not been previously reported in the literature with the use of BOC.

关键词： Hepatitis C Treatment Boceprevir Telaprevir Adverse events

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Typical Aspects of the Granular Cell Tumor of the Oral Cavity

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International Journal of Otolaryngology and Head & Neck Surgery 2014年第6期3卷 318-322页

作者： Paula Prieto-Oliveira Sergio Vitorino Cardoso Florence Zumbaio Mistro Sergio Kignel suzana Cantanhede Orsini Machado de Sousa Marco Tullio Brazao-silva Inter-Institutional Grad Program on Bioinformatics University of Sao PauloSao PauloBrazil Department of Oral Pathology School of DentistryFederal University of UberlandiaUberlandiaBrazil Department of Semiology School of DentistryFundacao Herminio OmettoArarasBrazil Department of Oral Pathology School of DentistryUniversity of Sao PauloSao PauloBrazil Department of Oral Diagnosis School of DentistrySchool of Health SciencesUniversity of the State of AmazonasManausBrazil

Granular cell tumor (GCT) is a rare neoplasm that can occur in any part of the body, but mostly they are located intraorally. Its histogenetic origin remains controversial, but it probably arises from Schwann cells and is generally benign. The tumor is typically asymptomatic and appears as a nodule, with a relatively high predilection for the tongue. This article reports a case of a 72-year-old woman treated at the Center of Oral Diagnosis of the Fundação Hermínio Ometto Dental School. The patient presented with an asymptomatic nodule in the dorsal surface of the tongue for approximately 4 months. The patient was submitted to an excisional biopsy and histopatological examination revealed polyhedral cells with granular aspect. The immunohistochemical staining for S-100 presented strong reactivity, confirming the diagnosis of GCT. Finally, we made a concise discussion about the pathogenesis and fundamental clinico-pathological aspects of GCT making the differential diagnosis.

关键词： Granular Cell Tumor Mouth Diagnosis

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Paclobutrazol on <i>In Vitro</i>Growth and Development of <i>Zygopetalum crinitum</i>Orchid, and on Seedling Acclimatization

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American Journal of Plant Sciences 2018年第5期9卷 1029-1036页

作者： Renata Gimenes Kathia Fernandes Lopes Pivetta Renata Bachin Mazzini-Guedes Marcos Vieira Ferraz suzana Targanski Sajovic Pereira águila silva Santos Ricardo Tadeu de Faria Lívia Caroline Praseres de Almeida Sao Paulo State University—UNESP Jaboticabal Brazil Federal University of Paraná—UFPR Jandaia do Sul Brazil State University of Londrina—UEL Londrina Brazil

In vitro cultivation is a technique that allows the production of great amount of plants. However, significant losses may occur during the acclimatization period (ex vitro stage). The objective of this study was to evaluate the effect of paclobutrazol, in the Murashige and Skoog culture medium, on growth, development, and survival of Zygopetalum crinitum plants. The experimental design (both in vitro and ex vitro) was completely randomized with four treatments: three paclobutrazol concentrations (0.5;1.0;and 1.5 mg L-1 active ingredient) and the control (without PBZ). Morphological changes promoted by the paclobutrazol application were observed in the seedlings;however, it did not result in higher seedling survival rates of the Zygopetalum crinitum orchid.

关键词： Growth Regulator Growth Retardant Triazol Orchidaceae

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Alto Pantanal地区的汞含量:一个透视研究

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人类环境杂志 1994年第8期23卷 478-484页

作者： Lars D. Hylander Edinaldo C. silva Lázaro J.Oliveira suzana A. silva Ellen K.Kuntze Donizete X.silva 马焕成 Swedish University of Agricultural Sciences Dept of soil sciences P. O. Box 7014 S-750 07 Uppsals Sweden UFMT公共卫生系马托格罗索州立矿业公司 Federal University of Mato Grosso UFMT.Dept.of Chemistry.Av. Fernando Correa s/No.CEP 78060 CUIABA-MTBrazil Federal University of Mato Grosso UFMT. Dept. of Chemistry. Av. Fernando Correa s/No. CEP 78 0 60 CUIABA-MT Brazil

采用附加有氢化物发生器的原子吸收光谱仪,测定了巴拉圭河上游流域内9个点的土壤、沉积物、鱼和鸟类羽毛中的汞含量。采金所大量使用的汞会直接散发至空气中或被河流运至Pantanal地区。Pantanal地区的生态系统不仅对在当地生活、捕鱼和... 详细信息

采用附加有氢化物发生器的原子吸收光谱仪,测定了巴拉圭河上游流域内9个点的土壤、沉积物、鱼和鸟类羽毛中的汞含量。采金所大量使用的汞会直接散发至空气中或被河流运至Pantanal地区。Pantanal地区的生态系统不仅对在当地生活、捕鱼和饲养牲畜的人们来说很重要,而且对远方城市的居民也很重要,因为城市居民所吃的鱼来自这一地区。他们还可从这一地区的旅游业中得到许多经济实惠等。当地重要的商品是鲇鱼(Pseudo-platystoma coruscans),但其中的汞含量已超过可食用的上限值(0.5ppm湿重),且远远超过自然本底值。鸟类羽毛中的汞含量也表明了这种生物富集作用。土壤和沉积物中的汞积累未达到统计学上的显著水平。汞齐化过程排放的汞比土壤矿物中固有的汞更易被生物所利用。采金过程中的汞回收技术并没有阻止汞的扩散。限制国际范围内的汞交易可能会显著减少汞的污染。

关键词：巴西 Alto Pantanal 汞含量环境污染测定

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