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A case of conjunctival intraepithelial neoplasia with spheroidal degeneration:a clinicopathological study

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International Journal of Ophthalmology(English edition) 2022年第8期15卷 1401-1403页

作者： Shoichiro Ota Satoru Kase Takayuki Tanaka susumu ishida Department of Ophthalmology Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo 060-8638Japan

Dear Editor,I am Shoichiro Ota from Hokkaido University hospital,Japan.Conjunctival intraepithelial neoplasia(CIN)is a disease concept that includes dysplasia and carcinoma in situ.Pathologically,CIN is characterized by tumor cell proliferation located within the epithelium with preservation of the basement membrane[1].In addition to histological diagnosis,anterior segment optical coherence tomography(ASOCT)plays an important role in clinical diagnosis,showing diffuse epithelial thickening with homogeneous high-intensity reflection in case of CIN[2-3].

关键词： diagnosis degeneration neoplasia

Conjunctival cyst with apocrine hidrocystoma-like features:a case report

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International Journal of Ophthalmology(English edition) 2023年第3期16卷 465-467页

作者： Takafumi Igarashi Satoru Kase Yuka Suimon Emi Takakuwa susumu ishida Department of Ophthalmology Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo 0608638Japan Department of Surgical Pathology Hokkaido University HospitalSapporo 0608638Japan

Dear Editor,I am Takafumi Igarashi from Hokkaido University Hospital,Japan.Apocrine hidrocystoma is a benign cystic tumor arising in the apocrine sweat glands proposed by Mehregan^([1])in 1964.It is likely that apocrine hidrocystoma arises in the uvula,ears,chest,and shoulders,as well as the (peri)ocular regions such as the eyelid,and sclera^([2-4]).

关键词： apo ocular likely

Laser speckle flowgraphy findings in a patient with radiation retinopathy

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International Journal of Ophthalmology(English edition) 2022年第1期15卷 172-174页

作者： Satoru Kase Ayaka Hasegawa Kiriko Hirooka Hiroaki Endo Kousuke Noda susumu ishida Department of Ophthalmology Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo 060-8638Japan Department of Ophthalmology Teine Keijinkai HospitalSapporo 006-0811Japan

Dear Editor,I am Satoru Kase, from Hokkaido University Hospital, Japan. Choroidal melanoma is a serious intraocular tumor, which threatens patients’ vision and life. Treatments for choroidal melanoma consist of surge... 详细信息

关键词： melanoma surgery intraocular

Histological observation in pachyvessels in a patient with choroidal melanoma

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International Journal of Ophthalmology(English edition) 2021年第5期14卷 777-779页

作者： Satoru Kase Kousuke Noda susumu ishida Department of Ophthalmology Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo 060-8638Japan

Dear Editor,I am Dr.Satoru Kase,from the Department of Ophthalmology,Faculty of Medicine and Graduate School of Medicine,Hokkaido University.I write to present a case of choroidal melanoma arising from a thickened choroid.The"pachychoroid"has recently been proposed as an entity comprising an increase in the choroidal thickness and dilatation of large choroidal vessels(so-called pachyvessels)[1].

关键词： choroidal melanoma Medicine

Increased plasma galectin-1 correlates with advanced glycation end products and interleukin-1β in patients with proliferative diabetic retinopathy

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International Journal of Ophthalmology(English edition) 2019年第4期12卷 692-694页

作者： Keitaro Hase Atsuhiro Kanda Kousuke Noda susumu ishida Laboratory of Ocular Cell Biology and Visual Science Department of Ophthalmology Faculty of Medicine and Graduate School of Medicine Hokkaido University

Dear Editor,Galectin-1, one of galactoside-binding lectin family proteins, has been shown to regulate cell growth, migration, and proliferation, where it binds many receptors depending on their glycosylation profile, ... 详细信息

关键词： Increased plasma galectin-1 correlates with advanced glycation end products and interleukin-1β in patients with proliferative diabetic retinopathy diabetic retinopathy

A case of nodular posterior scleritis simulating intraocular tumor

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International Journal of Ophthalmology(English edition) 2019年第4期12卷 685-688页

作者： Yukiko Shibata Satoru Kase Kenichi Namba susumu ishida Department of Ophthalmology Social Medical Corporation Tokeidai Memorial Hospital Department of Ophthalmology Faculty of Medicine and Graduate School of Medicine Hokkaido University

Dear Editor,I am Dr. Yukiko Shibata, from the Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University. I write to present the case of posterior scleritis simulating intrao... 详细信息

关键词： nodular posterior scleritis intraocular tumor

A clinicopathological study on IgG4-related ophthalmic disease

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International Journal of Ophthalmology(English edition) 2018年第9期11卷 1539-1544页

作者： Yuka Suimon Satoru Kase Kan Ishijima Hiromi Kanno-Okada susumu ishida Department of Ophthalmology Faculty of Medicine and Graduate School of MedicineHokkaido University Department of Surgical Pathology Hokkaido University Hospital

AIM： To investigate clinicopathological features of immunoglobulin G4-related ophthalmic disease（IgG4-ROD）, and analyze the recurrence rates following systemic corticosteroid administration.METHODS： We retrospectively searched clinical features, laboratory and histological findings based on the medical records of 21 patients with IgG4-ROD. All the patients examined in this study underwent surgical resection in the ocular adnexal lesions and underwent histological evaluation. This study further investigated clinical and histopathological features of 15 patients who received systemic corticosteroid after the resection.RESULTS： The mean age of the patients consisting of 7 males（33%） and 14 females（67%） was 61y. Fourteen patients were diagnosed as definitive, and 2 and 5 patients were probable and possible IgG4-ROD, respectively. Eyelid swelling was an initial symptom in 11 patients（52%） who did not show systemic involvements at a diagnosis. Fifteen patients received systemic corticosteroid administration, and all showed remission of inflammation. Among them, 10 patients did not recur, whereas 5 patients（33%） recurred during tapering. There were no significant difference between patients with or without recurrence in clinicopathological features.CONCLUSION： In this study, female patients are more predominant in IgG4-ROD. While inflammation recurs in one-third of patients, this study do not identify factors associated with recurrence after systemic corticosteroid administration.

关键词： IgG4-related ophthalmic disease corticosteroid histopathology recurrence

Anterior proliferative vitreoretinopathy in a patient with Coats disease

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International Journal of Ophthalmology(English edition) 2018年第2期11卷 343-345页

作者： Satoru Kase Shohei Mori Kousuke Noda susumu ishida Department of Ophthalmology Faculty of Medicine and Graduate School of Medicine Hokkaido University

Dear Editor,I am Satoru Kase,from the Department of Ophthalmology,Faculty of Medicine and Graduate School of Medicine,Hokkaido University,Sapporo,Japan.I write to present a case of Coats disease showing anterior proli... 详细信息

关键词： PVR NVG Anterior proliferative vitreoretinopathy in a patient with Coats disease

Histological observation of trabecular meshwork in a patient with Axenfeld-Rieger syndrome——a new theory for the mechanism of ectropion uvea in congenital glaucoma

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International Journal of Ophthalmology(English edition) 2020年第7期13卷 1167-1169页

作者： Satoru Kase Shinki Chin Teruhiko Hamanaka Yasuhiro Shinmei Takeshi Ohguchi susumu ishida Department of Ophthalmology Faculty of Medicine and Graduate School of MedicineHokkaido UniversitySapporo CityHokkaido 060-8638Japan Department of Ophthalmology Japan Red Cross Medical CenterTokyo 150-8935Japan

Dear Editor,I am Dr.Satoru Kase,from the Department of Ophthalmology,Faculty of Medicine and Graduate School of Medicine,Hokkaido University.I write to present the case of clinicopathological findings in Axenfeld-Rieg... 详细信息

关键词： Medicine Rieger congenital