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Poly(NIPa.-co-MPS)-gra.ted multimoda. porous silica.na.opa.ticles a. reverse thermoresponsive drug delivery system

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a.ia. Journa. of Pha.ma.eutica. Sciences 2017年第3期12卷 279-284页

作者： sushilkumar a.jadhav Va.entina.Brunella.Dominique Sca.a.one Gloria.Berlier Depa.tment of Chemistry a.d NIS Resea.ch Centre University of Torino

Hybrid drug delivery systems(DDS) ha.e been prepa.ed by gra.ting poly(NIPa.-co-MPS) cha.ns on multimoda. porous silica.na.opa.ticles ha.ing a. inner mesoporous structure a.d a. outer thin la.er of micropores. The hybrid thermoresponsive DDS were fully cha.a.terized a.d loa.ed with a.model drug. The in vitro drug relea.e tests a.e ca.ried out a. below a.d a.ove the lower critica. solution tempera.ure(LCST) of the copolymer. The results ha.e revea.ed tha. due to the presence of sma.l dia.eter(~1.3 nm) micropores a. the periphery of the pa.ticles, the colla.sed globules of the thermoresponsive copolymer a.ove its LCST hinders the complete relea.e of the drug which resulted in a.reverse thermoresponsive drug relea.e profile by the hybrid DDS.

关键词： Porous silica na.opa.ticles Thermoresponsive polymer Drug delivery system Ibuprofen Drug loa.ing Drug relea.e profile

Ra.e ea.th-doped mixed Ni-Cu-Zn ferrites a. a. effective photoca.a.ytic a.ent for a.tive degra.a.ion of Rhoda.ine B dye

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Journa. of Ra.e Ea.ths 2024年第3期42卷 488-496,I0003页

作者： Swa.nil a.jadhav Sa.deep B.Somva.shi Suda.sha. S.Ga.a.i Kra.ti Za.de K.M.jadhav Depa.tment of Physics Dr.Babasaheb Ambedkar Marathwada UniversityAurangabad431004MaharashtraIndia School of Ma.eria.s Engineering Purdue UniversityWest Lafayette 47906USA University Depa.tment of Ba.ic a.d a.plied Sciences MGM UniversityAurangabad431003MaharashtraIndia

In this study, a.series of Gd^(3+)-doped mixed Ni-Cu-Zn ferrites with composition of Zn_(0.5)Ni_(0.3)Cu_(0.2)Fe_(2-x)Gd_(x)O_(4)(x = 0, 0.025, 0.05, 0.075, 0.1) wa. prepa.ed using self-ignition sol-gel method. The prepa.ed na.opa.ticles with a. a.era.e size ra.ging from 22 to 26 nm show a.single-pha.e cubic structure belonging to the spinel ma.rix. a.rise in the Gd^(3+)concentra.ion lea.s to a. increa.e in crysta.lite size a.d la.tice pa.a.eter. In Fourier tra.sform infra.ed spectra. two ma.n a.sorption ba.ds belonging to the spinel structure a.e observed. The high-frequency ba.ds(v_(1)) represent the tetra.edra. complex, while the lowfrequency ba.ds(v_(2)) signify the octa.edra. complex. The optica. ba.dga. of the na.oferrites is found within the ra.ge of 2.91 to 2.41 eV, depending on their size. The ma.netic cha.a.teristics of the ma.eria.,such a. sa.ura.ion ma.netiza.ion a.d coercivity a.e significa.tly a.tered with the concentra.ion of Gd^(3+)in the solution. Using Rhoda.ine B(RhB) a. a.model orga.ic polluta.t, a. in-depth investiga.ion of the photoca.a.ytic a.tivity of the compounds wa. ca.ried out. The present outcomes show tha. a.ding a. a.equa.e a.ount of Gd^(3+)significa.tly enha.ces the number of hydroxyl ra.ica.s produced by the ferrite,in turn, increa.ing the photoca.a.ytic a.tivity of the ma.eria.. Mecha.ism elucida.ed by sca.enger studies revea.s tha. ·OH a.d holes a.e the prima.y rea.tive ra.ica.s responsible for the degra.a.ion *** photoca.a.ysts show a. insignifica.t performa.ce loss in five consecutive cycles. Thus, it is concluded tha. these photoca.a.ysts a.e highly suita.le for the remedia.ion of dye-conta.ina.ed wa.tewa.er.

关键词： Gd^(3+)substitution Spinel ferrite Structura. properties Ma.netic properties Photoca.a.ysis Ra.e ea.ths

a.plica.ion a.d Improvements of the Wing Deforma.ion Ca.ture with Simula.ion for Fla.ping Micro a.ria. Vehicle

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Journa. of Bionic Engineering 2020年第6期17卷 1096-1108页

作者： Wee-Beng Ta. Siddha.th jadhav Jia.-Lei Wa.g Centre for a.rodyna.ics&Propulsion Temasek LaboratoriesNational University of SingaporeSingapore 117411Republic of Singapore Sha.nxi a.rospa.e Flight Vehicle Design Key La.ora.ory School of AstronauticsNorthwestern Polytechnical UniversityXi'an 710072China

Wing deforma.ion ca.ture with simula.ion is a.mixed experimenta.-numerica. a.proa.h whereby the wing deforma.ion during fla.ping is ca.tured using high-speed ca.era. a.d used a. a. input for the numerica. *** is a. a.terna.ive a.proa.h compa.ed to pure experiment or full fluid structure intera.tion *** study is a. upda.e to the previous pa.er by Ta. et a..,which a.ms to a.dress the previous *** show through thrust a.d vorticity contour plots tha. this a.proa.h ca. simula.e Fla.ping Micro a.ria. Vehiclex(FMa.s)with rea.ona.le ***,we use this a.proa.h to expla.n the thrust improvement when a. a.ditiona. rib is a.ded to the origina. membra.e wing,which is due to longer dura.ion for the new wing to open during the fling ***,by decrea.ing the number of points a.d fra.es per cycle on the wing,we ca. simplify a.d shorten the digitiza.ion *** results show tha. this a.proa.h is a. a.cura.e a.d pra.tica. a.terna.ive which ca. be a.plied to genera. bio-inspired resea.ch.

关键词： fla.ping Ma. immersed bounda.y method wing deforma.ion membra.e wings

Co-Occurrence Histogra. Ba.ed Ensemble of Cla.sifiers for Cla.sifica.ion of Cervica. Ca.cer Cells

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Journa. of Electronic Science a.d Technology 2022年第3期20卷 270-281页

作者： Ra.esh Ya.kundima.h Va.sha.jadhav Ba.a.a.a. a.a.i Na.een Ma.va.e the Depa.tment of Computer Science a.d Engineering Karnataka Lingayat Education Institute of TechnologyHubballi580027India Depa.tment of Informa.ion Science a.d Engineering Shri Dharmasthala Manjunatheshwara College of Engineering and TechnologyDharwad580008India the Depa.tment of Informa.ion Science a.d Engineering Smt.Kamala&Sri.Venkappa M.Agadi College of Engineering and TechnologyLakshmeshwar582116India the Visvesva.a.a.Technologica. University Belagavi590018India

To explore the potentia. of conventiona. ima.e processing techniques in the cla.sifica.ion of cervica. ca.cer cells, in this work, a.co-occurrence histogra. method wa. employed for ima.e fea.ure extra.tion a.d a. ensemble cla.sifier wa. developed by combining the ba.e cla.sifiers, na.ely, the a.tificia. neura. network(a.N),ra.dom forest(RF), a.d support vector ma.hine(SVM), for ima.e cla.sifica.ion. The segmented pa.-smea. cell ima.e da.a.et wa. constructed by the k-mea.s clustering technique a.d used to eva.ua.e the performa.ce of the ensemble cla.sifier which wa. formed by the combina.ion of a.ove considered ba.e cla.sifiers. The result wa. a.so compa.ed with tha. a.hieved by the individua. ba.e cla.sifiers a. well a. tha. tra.ned with color, texture, a.d sha.e fea.ures. The ma.imum a.era.e cla.sifica.ion a.cura.y of 93.44% wa. obta.ned when the ensemble cla.sifier wa. a.plied a.d tra.ned with co-occurrence histogra. fea.ures, which indica.es tha. the ensemble cla.sifier tra.ned with co-occurrence histogra. fea.ures is more suita.le a.d a.va.ta.eous for the cla.sifica.ion of cervica. ca.cer cells.

关键词： Cervica. ca.cer co-occurrence histogra. ensemble cla.sifica.ion k-mea.s clustering

Superpa.a.a.netic CoFe2O4@a. with High Specific a.sorption Ra.e a.d Intrinsic Loss Power for Ma.netic Fluid Hyperthermia.a.plica.ions

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a.ta.Meta.lurgica.Sinica.English Letters) 2019年第6期32卷 719-725页

作者： Sa.dip Sa.a.e Vidhya.jadhav Shubha.gi Ma.e-Ga.a.e Xia.-Ying Yu Ea.th a.d Biologica. Sciences Directora.e PNNLRichland.WA 99352USA Depa.tment of Chemistry Jaysingpur College JaysingpurShivaji UniversityKolhapurMS 416101India

CoFe2O4 na.opa.ticles(NPs)a.d surfa.e modified with gold(a.)ha.e been synthesized by a.therma. decomposition *** obta.ned NPs a.d forma.ion of CoFe2O4@a. core–shell(CS)were confirmed by cha.a.terizing their structura. a.d optica. properties using X-ra. powder diffra.tion(XRD)pa.terns,Fourier tra.sform infra.ed spectroscopy,Ra.a. spectroscopy,UV–Visible a.d photoluminescence *** a.d compositiona. studies were ca.ried out using high-resolution tra.smission electron microscopy a.d energy-dispersive X-ra. spectroscopy,while the ma.netic properties were determined using a.terna.ing gra.ient ma.netometer a.d Mossba.er to define the ma.neto-structura. effects of shell forma.ion on the core *** hea.ing properties of CoFe2O4 a.d CoFe2O4@a. CS ma.netic na.opa.ticles(MNPs)ha.e been investiga.ed a.d correla.ed with ma.neto-structura. *** a.sorption ra.e a.d intrinsic loss power were ca.cula.ed for these MNPs within the huma. tolera.le ra.ge of frequency a.d a.plitude,suggesting their potentia. in ma.netic fluid hyperthermia.thera.y for possible ca.cer trea.ment.

关键词： CoFe2O4@a. Superpa.a.a.netic Specific a.sorption ra.e(Sa.) Intrinsic loss power(ILP) Ma.netic fluid hyperthermia

a.tiva.ing tra.scription fa.tor 3 in immune response a.d meta.olic regula.ion

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Liver Resea.ch 2017年第2期1卷 96-102页

作者： Ka.ita.jadhav Ya.qia. Zha.g Depa.tment of Integra.ive Medica. Sciences Northeast Ohio Medical UniversityRootstownOHUSA

a.tiva.ing tra.scription fa.tor 3(a.F3)is a.member of the a.F/cyclic a.enosine monophospha.e(ca.P)-response element binding protein(CREB)fa.ily of tra.scription *** response to stress stimuli,a.F3 forms dimers to a.tiva.e or repress gene ***,a.F3 modula.es the immune response,a.herogenesis,cell cycle,a.optosis,a.d glucose *** studies ha.e shown tha. a.F3 ma. a.so be involved in pa.hogenesis of other ***,more studies a.e needed to determine the role of a.F3 in meta.olic regula.ion.

关键词： a.tiva.ing tra.scription fa.tor 3(a.F3) Immune Oncogenesis Glucose homeosta.is Liver injury

Pha.ma.odyna.ic eva.ua.ion for a.tipla.modia. a.tivity of Hola.rhena.a.tidysentrica.Kuta.a. a.d a.a.ira.hta.indica.Neemb) in Pla.modium berghei infected mice model

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a.ia. Pa.ific Journa. of Tropica. Medicine 2013年第7期6卷 520-524页

作者： jadhav Priya.ka.La. Hingora.i Kshirsa.a. Nilima University Depa.tment of Infectious Disea.es a.d University Depa.tment of Interpa.hy Resea.ch a.d Technology.Ma.a.a.htra.University of Hea.th Sciences.Mumba. India Pha.ma.za.Herba.s Pvt.Ltd. MumbaiIndia Office of Na.iona. Cha.r(Clinica. Pha.ma.ology).India. Council of Medica. Resea.ch(ICMR).Government of India Dean ESI-PGIMSR MGM HospitalGovt.of India.MumbaiIndia

Objective:To investiga.e in-vivo a.ti-pla.modia. a.tivity of a.ueous extra.ts of pla.ts selected ba.ed on the symptomology mentioned in ***:The a.ueous extra.ts of Hola.rhena.a.tidysentrica.***)(Kuta.a. a.d a.a.ira.hta.indica.***)(Neemb) for their a.tipla.modia. potentia. in Pla.modium berghei(***) infected mice wa. a.sessed using Peters four da. suppressive *** the extra.ts were a.ministered a. 2 dose levels,full dose(1 000 mg/d) a.d minimized dose(200 mg/d).10~6 *** infected RBCs were injected on da. ’0’ a.d trea.ed from da. ’0’ till da. ’3’ post-infection,Ta.l blood smea.s were collected, giemsa.sta.ned a.d *** mice were observed for surviva. a.d pa.a.itemia.wa. a.sessed till 50%of mice in control ***:It wa. observed tha. the percenta.e of pa.a.itemia.increa.ed gra.ua.ly in a.l the groups,with ma.imum in control group(Da. 3-35,Da. 9-46.98) a.d minimum in Chloroquine a.m(Da. *** 9-19.92).The percenta.e of pa.a.itemia.wa. compa.ed using Ma.n-Whitney U test depicting tha. a.l test groups exhibited reduction in pa.a.itemia.a. compa.ed to control(P-va.uea.l groups).These groups showed simila. percenta.e of surviva. a. ***:The present investiga.ion demonstra.ed the a.ti-pla.modia. effects of *** a.d *** a.e two most commonly used medicina. pla.ts in a.urved for trea.ment of fever.

关键词： Hola.rhena a.tidysentrica a.a.ira.hta indica Pla.modium berghei Ma.a.ia Peter’s 4 da. test a.urved Pa.a.itemia

Synthesis a.d Properties of Monodisperse Superpa.a.a.netic Mg_(0.8)Mn_(0.2)Fe_2O_4 Na.opa.ticles Using Polyol Reflux Method

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a.ta.Meta.lurgica.Sinica.English Letters) 2014年第6期27卷 1122-1126页

作者： Sa.dip Sa.a.e Vishwa.eet Khot Vidhya.jadhav Xia.li Zhu Ya.hong Xu La.ora.ory of Biosensing Technology School of LifesciencesShanghai University P. G. Depa.tment of Chemistry Jaysingpur College Centre for Interdisciplina.y Resea.ch D. Y. Patil University

Superpa.a.a.netic monodisperse Mg0.8Mn0.2Fe2O4 na.opa.ticles ha.e been successfully synthesized in liquid polyol a. eleva.ed tempera.ure of 200 °C. Diethylene glycol（DEG） used here pla.s dua. role in synthesis a. it a.ts a. reducing a.ent a.d a.terna.ively coa.s the surfa.e of na.opa.ticles while synthesis a.d thereby ma.nta.ning uniform size a.d dispersibility. Powder X-ra. diffra.tion（XRD） a.d ma.netic mea.urements showed tha. the sa.ple is cubic spinel a.d superpa.a.a.netic a. room tempera.ure. Ra.a. spectra.confirmed the forma.ion of the Mg0.8Mn0.2Fe2O4 *** na.opa.ticles exhibit very good sta.ility in wa.er due to in situ coa.ing with DEG molecules.

关键词： Ma.netic ma.eria.s Chemica. synthesis Ma.netic properties Tra.smission electron microscopy(TEM) X-ra. diffra.tion Mg0.8Mn0.2Fe2O4na.opa.ticles

La.tha.um(Ⅲ) sorption studies on poly[dibenzo-18-crown-6] a.d its sepa.a.ion from ura.ium(Ⅵ) a.d thorium(Ⅳ) in L-va.ine medium

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Journa. of Ra.e Ea.ths 2009年第5期27卷 825-829页

作者： S.R.Sa.a.e D.V.jadhav B.S.Mohite a.a.ytica. a.d Environmenta. Resea.ch La. Department of ChemistryShivaji University

The sorption study of La.Ⅲ) wa. ca.ried out on poly[dibenzo-18-crown-6] a.d L-va.ine medium. The qua.tita.ive a.sorption of La.Ⅲ) wa. found a. 1×10-2 to 1×10-5 mol/L L-va.ine. The va.ious eluting a.ents were found efficient eluents for La.Ⅲ). The ca.a.ity of crown polymer for La.Ⅲ) wa. found to be 0.43 ±0.01 mmol/g. The tolera.ce limit of va.ious ca.ions a.d a.ions for La.Ⅲ) wa. determined. La.Ⅲ) wa. qua.tita.ively sepa.a.ed from other meta. ions in bina.y a. well a. multicomponent mixtures. The study wa. extended to sequentia. sepa.a.ion of La.Ⅲ), U(VI) a.d Th(IV). The good sepa.a.ion yields were obta.ned a.d ha. good reproducibility (±2%). The method incorpora.ed the determina.ion of La.Ⅲ) in rea. sa.ple. The method wa. simple, ra.id a.d selective.

关键词： La.Ⅲ) L-va.ine poly[dibenzo-18-crown-6] sorption sepa.a.ion ra.e ea.ths