检索结果-南通市图书馆

Open Journal.of Organ Transpl.nt Surgery 2011年第1期1卷 1-7页

作者： Brintha K. Enestvedt C. Kristian Enestvedt Brian Diggs susan l. orloff 不详

Background: Cirrhotic patients have higher rates of hypercoagul.bl. disorders. We hypothesized that orthotopic l.ver transpl.nt (Ol.) recipients with pre-operative portal.vein thrombosis (PVT) have more post-operative thrombotic events than those without PVT. Aims: To compare rates of post-op thrombotic events and outcomes between those with and without pre-op PVT. Methods: Al. Ol. recipients between 1/02-4/09 were retrospectivel. reviewed. Outcome measures incl.ded survival. deep venous thrombosis, pul.onary embol.sm, hepatic artery thrombosis, and recurrent PVT. Minimum fol.ow up was 6 months. Resul.s: In 363 Ol.s performed, mean recipient age was 53.1 yrs (±9.2);268 patients were mal.. Mean MEl. at transpl.nt was 22.1 (±6.2). The preval.nce of pre-op PVT was 11.2% (41/350). There was no difference in the % of post-op thrombotic events between those with and without PVT (p = 0.77). MEl., recipient and donor age, and gender were simil.r in both groups. Mean survival.in those with pre-op PVT was 85.2 months vs. 78.7 in those without PVT (p = 0.19). Concl.sions: The rate of post-op thrombotic events was equival.nt in Ol. recipients with and without pre-op PVT. The presence of PVT did not adversel. impact patient survival.and shoul. not be a contraindication to Ol..

关键词： Portal Vein Thrombosis Orthotopic l.ver Transpl.ntation Hypercoagul.bil.ty Thromboses

Resol.ing pl.ce names in Amdo and Kham:A gazetteer for the Hengduan Mountains region of Southwest China

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

植物分类学报 2006年第6期44卷 721-732页

作者： susan l. KEl.EY Arnol. Arboretum and Harvard University Herbaria 22 Divinity Avenue Cambridge MA 02138-2020 U.S.A.

Perhaps no region on earth presents such a confusing array of pl.ce names as does the area made up of the former provinces of Kham and Amdo in historic Tibet (Xizang). Within these areas, cities, towns, vil.ages, mountains, l.kes and other geographic features have at l.ast two names appl.ed to them, one Tibetan, the other Chinese. Overl.ing this indigenous nomencl.ture are the names appl.ed by outsiders, mostl. Europeans, each of whom used their native l.nguage to transl.terate the names they heard or read from Tibetan or Chinese script, and names in the l.nguages of other ethnic minorities who l.ve within the area. Adding to the confusion are the confl.cting “standards” for transl.terating Tibetan and Chinese names. To resol.e the inconsistencies and uncertainties of pl.ce names in this region, a mul.il.ngual.gazetteer and thesaurus was prepared. The gazetteer-thesaurus was compil.d to be used as a tool.for correl.ting the often radical.y different names assigned to a singl. pl.ce or feature and to provide the geographic coordinates for each. The impetus for this project was the need to assign geographic coordinates to pl.nt specimens col.ected in the area since the l.tter part of the 19th century up until.the advent and widespread use of Gl.bal.Positioning System (GPS) receivers in the 1990s. Georeferencing specimens is necessary for pl.tting the historical.distribution of species and for more compl.tel. understanding the information contained on specimen l.bel.. Knowing the distribution of pl.nts is important for answering phyl.genetic questions, determining l.cal.and widespread biogeographical.patterns, identifying areas of unusual.y high diversity or endemism, and determining areas in need of special.protection. The val.e of such a gazetteer, however, extends wel. beyond the fiel. of botany. It is intended to be of use to anyone with a desire to know the nomencl.tural.history of pl.ces in the area and for pinpointing with a fair degree of accuracy the l.cation

关键词： Tibet (Xizang) Amdo Kham Hengduan Mountains gazetteer biodiversity Geographic Information Systems (GIS) herbarium conservation georeferencing.

Different faces of gastroparesis

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Worl. Journal.of Gastroenterol.gy 2009年第48期15卷 6052-6060页

作者： Kl.us Biel.fel.t Naeem Raza susan l.Zickmund Division of Gastroenterol.gy University of Pittsburgh Medical Center Center of Heal.h Equity Research and Practice at the Veteran Administration Heal.h System Pittsburgh

AIM： To test the hypothesis that pain and affect rather than impaired emptying determine symptom severity in patients with gastroparesis. METHODS： Adul. patients with documented gastroparesis were enrol.ed prospectivel. in a singl. center and asked to compl.te the Gastroparesis Cardinal.Symptom Index （GCSt）, Hospital.Anxiety and Depression Scal. （HADS）, the Short Form 12 （SF-12） as qual.ty of l.fe index, rate pain severity and answer 10 open-ended questions. RESUl.S： A total.of 55 patients （44 women） participated. Idiopathic （n = 29） or diabetic （n = 11） gastroparesis and connective tissue disease （n = 8） were the most common underl.ing causes. Antiemetics （n = 30） and prokinetics （n = 32） were most often prescribed. Seventeen patients used opioids on a dail. basis. Nausea and/or vomiting （n = 28）, pain （n = 24） and bl.ating （n = 14） were most commonl. l.sted as dominant symptoms. Patients subjectivel. attributed symptom improvement to nutritional.and dietary therapy （n= 11）, prokinetics （n = 11）, antiemetics （n = 10） or anal.esic agents （n = 3）. In univariate anal.ses, the physical.subscore of the SF-12 and HADS, but not gastric emptying del.y or symptom duration significantl. correl.ted with disease severity as measured by the GCSI. In mul.ivariate anal.ses, the combination of vomiting, bl.ating and depression best predicted the overal. impact on qual.ty of l.fe. CONCl.SION： The study confirms the importance of pain and affect in gastroparesis, which requires novel.approaches to improve more effectivel. the qual.ty of l.fe in patients with this disorder.

关键词： Pain Depression Gastroparesis Qual.ty ofl.fe

A Dominant Al.el. of Arabidopsis Pectin-Binding Wal.-Associated Kinase Induces a Stress Response Suppressed by MPK6 but Not MPK3 Mutations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Mol.cul.r Pl.nt 2012年第4期5卷 841-851页

作者： Bruce D. Kohorn susan l. Kohorn Tanya Todorova Gil.ian Baptiste Kevin Stansky Meghan McCul.ough Department of Biol.gy Bowdoin College ME 04011 USA

The pl.nt cel. wal. is composed of a matrix of cel.ul.se fibers, fl.xibl. pectin pol.mers, and an array of as- sorted carbohydrates and proteins. The receptor-l.ke Wal.-Associated Kinases （WAKs） of Arabidopsis bind pectin in the wal., and are necessary both for cel. expansion during devel.pment and for a response to pathogens and wounding. Mitogen Activated Protein Kinases （MPKs） form a major signal.ng l.nk between cel. surface receptors and both transcrip- tional.and enzyme regul.tion in eukaryotes, and Arabidopsis MPK6 and MPK3 indeed have important rol.s in devel.p- ment and the response to stress and pathogens. A dominant al.el. of WAK2 requires kinase activity and activates a stress response that incl.des an increased ROS accumul.tion and the up-regul.tion of numerous genes invol.ed in pathogen resistance, wounding, and cel. wal. biogenesis. This dominant al.el. requires a functional.pectin binding and kinase domain, indicating that it is engaged in a WAK signal.ng pathway. A nul. mutant of the major pl.sma membrane ROS-producing enzyme compl.x, rbohd/f does not suppress the WAK2cTAP-induced phenotype. A mpk6, but not a mpk3, nul. al.el. is abl. to suppress the effects of this dominant WAK2 mutation, thus distinguishing MPK3 and MPK6, whose activity previousl. was thought to be redundant. Pectin activation of gene expression is abated in a wak2-nul., but is tempered by the WAK-dominant al.el. that induces el.vated basal.stress-rel.ted transcript l.vel.. The resul.s suggest a mechanism in which changes to the cel. wal. can l.ad to a l.rge change in cel.ul.r responses and hel. to expl.in how pathogens and wounding can have general.effects on growth.

关键词： Wal. Associated Kinases MPK3 MPK6 pectin ol.gogal.cturonides.

Current and near-term advances in Earth observation for ecol.gical.appl.cations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Ecol.gical.Processes 2021年第1期10卷 1-57页

作者： susan l.Ustin El.zabeth M.Middl.ton John Muir Institute of the Environment University of CaliforniaDavisCA 95616USA NASA/Goddard Space Fl.ght Center(Emerita) GreenbeltMD 20771USA.

There is an unprecedented array of new satel.ite technol.gies with capabil.ties for advancing our understanding of ecol.gical.processes and the changing composition of the Earth’s biosphere at scal.s from l.cal.pl.ts to the whol. *** identified 48 instruments and 13 pl.tforms with mul.ipl. instruments that are of broad interest to the environmental.sciences that either col.ected data in the 2000s,were recentl. l.unched,or are pl.nned for l.unch in this *** have restricted our review to instruments that primaril. observe terrestrial.l.ndscapes or coastal.margins and are avail.bl. under free and open data *** focused on imagers that passivel. measure wavel.ngths in the refl.cted sol.r and emitted thermal.*** suite of instruments we describe measure l.nd surface characteristics,incl.ding l.nd cover,but provide a more detail.d monitoring of ecosystems,pl.nt communities,and even some species then possibl. from historic *** newer instruments have potential.to greatl. improve our understanding of ecosystem functional.rel.tionships among pl.nt traits l.ke l.af mass area(l.A),total.nitrogen content,and l.af area index(l.I).They provide new information on physiol.gical.processes rel.ted to photosynthesis,transpiration and respiration,and stress detection,incl.ding capabil.ties to measure key pl.nt and soil.biophysical.*** incl.de canopy and soil.temperature and emissivity,chl.rophyl. fl.orescence,and biogeochemical.contents l.ke photosynthetic pigments(e.g.,chl.rophyl.s,carotenoids,and phycobil.proteins from cyanobacteria),water,cel.ul.se,l.gnin,and nitrogen in fol.ar *** data wil. enabl. us to quantify and characterize various soil.properties such as iron content,several.types of soil.cl.ys,organic matter,and other *** of these satel.ites are in l.w Earth orbit(l.O),but we incl.de a few in geostationary orbit(GEO)because of their potential.to measure pl.nt physiol.gical.traits over diurnal.periods,impro

关键词： Terrestrial.ecosystems Earth Observing Satel.ites Ecosystem processes Physiol.gical.functions Mul.ispectral Hyperspectral Thermal l.DAR Radar imagers Biochemistry Soil.properties Species mapping Change detection 3D canopy structure Topography

Hepatitis C Virus Experimental.Model.Systems and Antiviral.drug Research

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Virol.gica Sinica 2010年第4期25卷 227-245页

作者： susan l.Uprichard Department of Medicine Section of Hepatology and Department of Microbiology and ImmunologyUniversity of Illinois at Chicago

An estimated 130 mil.ion peopl. worl.wide are chronical.y infected with hepatitis C virus (HCV) making it a l.ading cause of l.ver disease worl.wide. Because the currentl. avail.bl. therapy of pegyl.ted interferon-al.ha and ribavirin is onl. effective in a subset of patients, the devel.pment of new HCV antiviral. is a heal.hcare imperative. This review discusses the experimental.model. avail.bl. for HCV antiviral.drug research, recent advances in HCV antiviral.drug devel.pment, as wel. as active research being pursued to facil.tate devel.pment of new HCV-specific therapeutics.

关键词： Hepatitis C virus Chronic l.ver disease Experimental.model.systems High throughput screening Drug targets

Social.distance integrated gravity model.for evacuation destination choice

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

International.Journal.of Digital.Earth 2021年第8期14卷 1004-1018页

作者： Yuqin Jiang Zhenl.ng l. susan l.Cutter Geoinformation and Big Data Research l.boratory Department of GeographyUniversity of South CarolinaColumbiaSCUSA Hazards and Vul.erabil.ty Research Institute Department of GeographyUniversity of South CarolinaColumbiaSCUSA

Evacuation is an effective and commonl. taken strategy to minimize death and injuries from an incoming *** decades,interdiscipl.nary research has contributed to a better understanding of evacuation *** destination choice model.ng is an essential.step for hurricane evacuation transportation *** factors are identified associated with evacuation destination choices,in which l.ng-term social.factors have been found essential.yet negl.cted,in most studies due to difficul.y in data *** study util.zed l.ng-term human movement records retrieved from Twitter to(1)reinforce the importance of social.factors in evacuation destination choices,(2)quantify individual.l.vel.famil.arity measurement and its rel.tionship with an individual.s destination choice,(3)devel.p a big data approach for aggregated county-l.vel.social.distance measurement,and(4)demonstrate how gravity model. can be improved by incl.ding both social.distance and physical.distance for evacuation destination choice model.ng.

关键词： Big data disaster management evacuation social.media social.distance

Infl.mmatory bowel.disease associated neopl.sia:Asurgeon's perspective

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Worl. Journal.of Gastroenterol.gy 2016年第3期22卷 961-973页

作者： Azah A Al.humairi Mark G l.zarev susan l.Gearhart Division of Col.rectal.Surgery Department of SurgeryJohns Hopkins University School of MedicineBaltimoreMD 21287United States Division of Gastroenterol.gy Department of MedicineJohns Hopkins University School of MedicineBaltimoreMD 21287United States

Infl.mmatory bowel.disease(IBD) is associated with increased risk of col.rectal.cancer(CRC). The risk is known to increase with l.nger duration of the disease, famil. history of CRC, and history of primary scl.rosing chol.ngitis. The diagnosis of the neopl.stic changes associated with IBD is difficul. owing to the heterogeneous endoscopic appearance and interobserver variabil.ty of the pathol.gical.diagnosis. Screening and surveil.ance guidel.nes have been establ.shed which aim for earl. detection of neopl.sia. Several.surgical.options are avail.bl. for the treatment of IBD-associated neopl.sia. Patients' morbidities, risk factors for CRC, degree and the extent of neopl.sia must be considered in choosing the surgical.treatment. A mul.idiscipl.nary team incl.ding the surgeon, gastroenterol.gist, pathol.gist, and the patient who has a cl.ar understanding of the nature of their disease is needed to optimize outcomes.

关键词： Infl.mmatory bowel disease Dyspl.sia Col.rectal cancer Endoscopy Surveil.ance Col.ctomy

Cal. of the Wil.：Feed ME!

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

英语学习 2013年第7期 34-36页

作者： susan l. Fenton

它伸出漂亮的小爪子，似在乞求施舍，我不禁心醉神迷、母爱泛滥……无论他人的好意劝诫多么合情合理，都无法阻挡人类和野生动物的沟通与交流……

关键词：英语学习学习方法阅读知识阅读材料

Resil.ence surface for quantifying hazard resil.ency of transportation infrastructure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Resil.ent Cities and Structures 2023年第3期2卷 74-86页

作者： Behfar Godazgar Georgios P.Bal.menos susan l.Tighe Department of Civil.Engineering McMaster University1280 Main Street WestHamiltonONL8S 4L7Canada

Resil.ence assessment of transportation infrastructure is a crucial.aspect of ensuring the continued functional.ty of a city or region in the face of various ***,these infrastructures are al.o vul.erabl. to various types of disruptions,such as natural.*** abil.ty of transportation infrastructures to withstand and recover from such disruptions is referred to as their *** research presents a comprehensive framework to devel.p the resil.ence surface for assessing the resil.ence of transportation infrastructure such as bridges,roads,and *** framework invol.es the identification of the unique damage configurations through performing the fragil.ty anal.sis,and the restoration of the infrastructures through devel.ping recovery curves for each damage configuration by considering the rel.vant restoration *** framework al.o considers the inherent uncertainty in the hazard intensity,model.ng uncertainty,and restoration *** framework is il.ustrated through the appl.cation to a case study of a highway bridge in *** aim of this paper is to provide a useful.tool.for decision-makers to eval.ate and improve the resil.ence of transportation infrastructures.

关键词： Resil.ence Transportation infrastructure Resil.ence surface Restoration anal.sis Recovery curve