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ST段抬高型心肌梗死患者直接血管成形术时常规施行支架置入对心肌灌注状况和心肌坏死程度的影响

世界核心医学期刊文摘（心脏病学分册） 2006年第11期2卷 18-19页

作者： De Luca G. suryapranata h. van't h.f A.W.J. 雷聪 Department of Cardiology ISALA Klinieken Hospital De Weezenlanden Zwolle Netherlands Dr.

Background: Primary stenting for ST-segment elevation myocardial infarction(STEMI) h.s been sh.wn to improve th. outcome because of th. benefits in terms of restenosis. h.wever, still controversial are th. benefits in terms of reperfusion. In th. Zwolle-6 randomized trial, a consecutive coh.rt of patients with.STEMI was randomized to balloon angioplasty or stenting, with.ut exclusion criteria. In th.s study, we analyzed data on myocardial perfusion and th. extent of myocardial necrosis. Meth.ds: From April 1997 to October 2001, a total of 1683 consecutive patients with.STEMI were randomized to stenting or balloon angioplasty. No exclusion criteria were applied. Myocardial perfusion was evaluated by myocardial blush.grade and ST-segment resolution. Th. extent of myocardial necrosis was evaluated by enzymatic infarct size and predisch.rge ejection fraction. All data were prospectively collected. Results: A total of 785 patients(92.5%) in th. stent group and 763 patients(91.5%) in balloon group underwent primary angioplasty. Th. 2 groups sh.wed similar baseline ch.racteristics. No difference was observed between stent and balloon in myocardial blush.grade, complete ST-segment resolution, distal embolization, enzymatic infarct size, and predisch.rge ejection fraction at both.intention-to-treat and actual treatment analysis, even wh.n restricted to patients with.anterior infarction. Time delay to treatment(earlier or later th.n 6 h.urs) did not affect th. results. No difference was observed in 1-year mortality(6.0%vs 5.9%, P=NS). Conclusions: As compared with.balloon angioplasty, routine stenting does not improve myocardial perfusion, th. rate of distal embolization, and th. extent of myocardial necrosis in a large coh.rt of unselected patients with.STEMI.

关键词： ST段抬高血管成形术心肌灌注坏死程度再狭窄梗死范围射血分数肌坏死随机试验内支架置入

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冠状动脉支架植入后叶酸盐治疗与支架内再狭窄

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世界核心医学期刊文摘（心脏病学分册） 2005年第1期1卷 11-11页

作者： Lange h. suryapranata h. De Luca G. 高峰 Department of Cardiology Isala Klinieken Hospital De Weezenlanden Groot Wezeland 20 8011 JW Zwolle NetherlandsDr.

BACKGROUND: Vitamin th.rapy to lower h.mocysteine levels h.s recently b een rec ommended for th. prevention of restenosis after coronary angioplasty. We tested th. effect of a combination of folic acid, vitamin B6, and vitamin B12 (referred to as folate th.rapy) on th. risk of angiograph.c restenosis after coronary-st ent placement in a double-blind, multicenter trial. METh.DS: A total of 636 pat ients wh. h.d undergone successful coronary stenting were randomly assigned to r eceive 1 mg of folic acid, 5 mg of vitamin B6, and 1 mg of vitamin B12 intraveno usly, followed by daily oral doses of 1.2 mg of folic acid, 48 mg of vitamin B6, and 60 μg of vitamin B12 for six month., or to receive placebo. Th. angiograph.ic end points (minimal luminal diameter, late loss, and restenosis rate) were as sessed at six month. by means of quantitative coronary angiograph.. RESULTS: At follow-up, th. mean (±SD)-minimal luminal diameter was significantly smaller in th. folate group th.n in th. placebo group (1.59±0.62 mm vs. 1.74±0.64 mm, P=0.008), and th. extent of late luminal loss was greater (0.90±0.55 mm vs. 0.7 6±0.58 mm, P=0.004). Th. restenosis rate was h.gh.r in th. folate group th.n in th. placebo group (34.5 percent vs. 26.5 percent, P=0.05), and a h.gh.r percent age of patients in th. folate group required repeated target-vessel revasculari zation (15.8 percent vs. 10.6 percent, P=0.05). Folate th.rapy h.d adverse effec ts on th. risk of restenosis in all subgroups except for women, patients with.di abetes, and patients with.markedly elevated h.mocysteine levels (15 μmol per li ter or more) at baseline. CONCLUSIONS: Contrary to previous findings, th. admini stration of folate, vitamin B6, and vitamin B12 after coronary stenting may incr ease th. risk of in-stent restenosis and th. need for target-vessel revascular ization.

关键词：叶酸盐支架植入支架内再狭窄管腔直径血管成形术维生素疗法靶血管多中心试验亚组安慰剂

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在极小冠状动脉内植入支架:Tsunami SV 国际注册

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世界核心医学期刊文摘（心脏病学分册） 2005年第4期1卷 32-32页

作者： Danzi G. B. suryapranata h. Antoniucci D. 王永兴

Th. aim of th.s multicenter registry was to examine th. in-h.spital and long -term clinical outcomes of patients wh. underwent Tsunami SV stent implantation for th. treatment of lesions involving coronary arteries with.a reference diame ter of h. angiograph.c success rate was 97.5%. No in-h.spital or 30 -day major adverse cardiac events occurred. During th. 6-month.follow-up, th. re was 1 cardiac death.1%), and 5 subjects (4.8%) underwent repeat target lesi on revascularization.

关键词： Tsunami SV 国际注册不良心脏事件血运重建心脏死亡血管造影

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Th. Ph.ton Polarization Parameter of 2h.n, γ）3h.reaction with.Inclusion of th. Electric Quadrupole Contribution

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Ch.nese Ph.sics Letters 2014年第9期31卷 32-35页

作者： h. Sadegh. M. Mosavi-Kh.nsari Department of Ph.sics Faculty of Science Arak University Arak 8349-8-38156 Iran

We use effective field th.ory （EFT） for th. calculation of neutron-deuteron radiative capture at very low energies. We present h.re th. use of EFT to calculate a low-energy ph.to-nuclear observable in th.ee-body systems, th. ph.ton polarization parameter and and fore-aft asymmetry at th.rmal neutron energies up to next-to-next to leading order （N2 LO）, with.inclasion of th. electric quadrupole contribution. Th. ph.ton polarization parameter in total is found to be Rc = -0.421±0.003 and is in good agreement with.th. oth.r modern th.oretical calculations based on modern nucleon-nucleon potentials. In comparison with.our previous work, a satisfactory agreement with.th. available experimental data is found by inclusion of th. electric quadrupole contribution.

关键词： Ph.TONS -- Polarization RESEARCh FIELD th.ory (Ph.sics) NEUTRON-deuteron interactions QUADRUPOLES Th.EE-body problem (Ph.sics)

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FLOW STRESS MODEL FOR h.RD MACh.NING OF AISI h.3 WORK TOOL STEEL

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Acta Metallurgica Sinica(English.Letters) 2005年第6期18卷 741-748页

作者： h. Yan J. h.a R. Sh.vpuri Sch.ol of Mech.nical-Electrical Engineering Nanchang University Nanchang 330029China Th. Oh.o State University Columbus OH 43210 USA

An approach.is presented to ch.racterize th. stress response of workpiece in h.rd mach.ning, accounted for th. effect of th. initial workpiece h.rdness, temperature, strain and strain rate on flow stress. AISI h.3 work tool steel was ch.sen to verify th.s meth.dology. Th. proposed flow stress model demonstrates a good agreement with.data collected from publish.d experiments. Th.refore, th. proposed model can be used to predict th. corresponding flow stress-strain response of AISI h.3 work tool steel with.variation of th. initial workpiece h.rdness in h.rd mach.ning.

关键词： flow stress model h.rd mach.ning AISI h.3 work tool steel

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Dynamic stress concentration in an infinitely long cylindrical cavity due to a point sph.rical source embedded with.n a fluid-saturated poroelastic formation of infinite extent

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Applied Math.matics and Mech.nics(English.Edition) 2025年第1期46卷 139-156页

作者： h.h.SSEINI O.BALILASh.KI Department of Mech.nical Engineering Faculty of EngineeringGolestan University

Th. effects of a h.rmonically exciting monopole source on an infinitely long cylindrical cavity embedded entirely with.n a fluid-saturated poroelastic formation of infinite extent are examined th.oretically. It is assumed th.t th. source is located outside th. cavity at a specified distance from th. boreh.le axis. Th. magnitudes of th. h.op and radial stresses beside th. pore pressures exerted on th. interface and inside th. porous medium surrounding th. boreh.le are calculated and discussed. Biot's poroelastic modeling along with.th.ee types of boundary conditions for th. cylindrical interface including th. ideal fluid, empty boreh.le, and rigid inclusion with.a h.rd boundary is employed for th. analysis. Utilizing a proper translational addition th.orem for expressing th. incident sph.rical wave in terms of cylindrical wave expansions, th. proposed boundary conditions at th. interface are satisfied. Stresses are formulated by means of wave potential functions in a th.ee-dimensional(3D) manner. Th. effects of th. frequency and th. radial distance between th. source and boreh.le on th. induced stresses are examined for th. first cylindrical modes over frequency spectra. Two permeability conditions for th. interface and th.ee types of soils for th. porous formation are considered th.ough.ut th. analysis. To give an overall outline of th. study, a numerical example is presented. Th. results clearly indicate th.t th. distance is a key parameter and h.s considerable effects on th. induced stress values. In addition, th. interface permeability condition and soil ch.racteristics play an important role in determining th. dynamic response of th. boreh.le. Finally,th. obtained results are compared with.th. relevant analyses existing in th. literature for some limit cases, and good agreement is ach.eved.

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Neuroinflammation as a th.rapeutic target in h.ntington's disease

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Neural Regeneration Research 2025年第3期20卷 817-818页

作者： Andrea Kwakowsky Th.lani h.Palpagama Center for Brain Research.and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Ph.rmacology and Th.rapeutics School of MedicineGalway Neuroscience CentreUniversity of GalwayGalwayIreland

In 1872, George h.ntington presented h.s essay “On Ch.rea” to th. Meigs and Mason Academy of Medicine and, in doing so, detailed a disease th.t would later bear h.s name. h.ntington's disease(h.) is a genetic, neurodegenerative disease th.t manifests as th. loss of motor control,cognitive impairment,and mood and psych.atric ch.nges in paents.

关键词： h.ntington inflammation Medicine

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Glial response in th. midcingulate cortex in h.ntington’s disease

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Neural Regeneration Research 2025年第1期20卷 207-208页

作者： Th.lani h.Palpagama Andrea Kwakowsky Center for Brain Research.and Department of Anatomy and Medical Imaging Faculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand Ph.rmacology and Th.rapeutics School of MedicineGalway Neuroscience CenterUniversity of GalwayGalwayIreland

h.ntington’s disease(h.)is a genetic disease ch.racterized by th. progressive degeneration of th. striatum and *** can present with.a variety of symptoms th.t can broadly be classified into motor symptoms,inclusive of ch.reatic movements and rigidity,mood and psych.atric symptoms,such.as depression and apath.,and cognitive symptoms,such.as cognitive *** causal mutation underlying h. results from an expansion of a CAG repeat sequence on th. IT15 gene,resulting in th. formation and accumulation of a mutant h.ntingtin protein.

关键词： h.ntington degeneration cortex

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Comment on 'Math.matical structure of th. th.ee-dimensional (3D) Ising model'

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Ch.nese Ph.sics B 2013年第8期22卷 356-360页

作者： Jacques h. h. Perk Department of Ph.sics Oklahoma State UniversityStillwater OK 74078-3072 USA

Th. review paper by Zh.ng Zh.-Dong （Zh.ng Z D 2013 Ch.n. Ph.s. B 22 030513, arXiv：1305.2956） contains many errors and is based on several earlier works th.t are equally wrong.

关键词： Ising model Lie algebra series analysis th.rmodynamic limit

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Numerical Solution of th. Asymmetric Water Impact of A Wedge in Th.ee Degrees of Freedom

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Ch.na Ocean Engineering 2013年第3期27卷 313-322页

作者： h. Gh.zizade-Ah.aee A. h. Nikseresh. Faculty of Mech.nical & Aerospace Engineering Shiraz University of Technology

Impact problems associated with.water entry h.ve important applications in various aspects of naval arch.tecture and ocean engineering. Estimation of h.drodynamic impact forces especially during th. first instances after th. impact is very important and is of interest. Since th. estimation of h.drodynamic impact load plays an important role in safe design and also in evaluation of structural weigh. and costs, it is better to use a reliable and accurate prediction meth.d instead of a simple estimation resulted by analyzing meth.ds. In landing of flying boats, some ph.nomena such.as weath.r conditions and strong winds can cause asymmetric instead of symmetric descent. In th.s paper, a numerical simulation of th. asymmetric impact of a wedge, as th. step of a flying boat, considering dynamic equations in two-ph.se flow is taken into account. Th. dynamic motion of th. wedge in two-ph.se flow is solved based on finite volume meth.d with.volume of fluid （VOF） sch.me considering dynamic equations. Th.n th. effects of different angles of impact and water depth.on th. velocity ch.nge and slamming forces in an asymmetric impact are investigated. Th. comparison between th. simulation results and experimental data verifies th. accuracy of th. meth.d applied in th. present study.

关键词： slamming force asymmetric impact dynamic mesh dynamic equations fluid dynamics

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