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Transactions of Nonferrous Metals Society of China 2021年第1期31卷 156-166页

作者： S.DHARANI kumar S.suresh kumar Department of Mechanical Engineering Sri Eshwar College of EngineeringCoimbatore641202Tamil NaduIndia Department of Mechanical Engineering Sri Sivasubramaniya Nadar College of EngineeringChennai603110Tamil NaduIndia

Ballistic behaviour of different zones of post-weld heat-treated(PWHT)magnesium alloy(AZ31B)target against 7.62 mm×39 mm armour-piercing(AP)projectile with a striking velocity of(430±20)m/s was *** alloy(AZ31B)welded joints were prepared by using friction stir welding(FSW)process and subjected to different heat treatment *** microhardness values of non-heat-treated and heat-treated FSW joints were *** results indicated that PWHT process(250°C,1 h)has improved the microhardness of heat-treated FSW *** electron microscope(SEM)microstructure showed that heat treatment has caused the formation of fineα-Mg grains and tiny precipitates and made the dissolution ofβ-Mg17Al12 phase into the Mg *** ballistic behaviour of PWHT zones was estimated by measuring the depth of penetration(DOP)of the *** DOP value was observed for the base metal zone(BMZ)of a heat-treated welded *** ballistic SEM examinations on the cross-section of all three zones of crater region showed the formation of adiabatic shear band(ASB).

关键词： AZ31B magnesium alloy post-weld heat treatment ballistic behaviour penetration depth adiabatic shear band

Anticancer potential of Alternanthera sessilis extract on HT-29 human colon cancer cells

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Asian Pacific Journal of Tropical Biomedicine 2018年第8期8卷 394-402页

作者： Sivapragasam Gothai Katyakyini Muniandy Norhaizan Mohd Esa suresh kumar Subbiah Palanisamy Arulselvan Laboratory of Vaccines and Immunotherapeutics Institute of Bioscience Universiti Putra Malaysia Department of Nutrition and Dietetics Faculty of Medicine and Health Sciences Universiti Putra Malaysia Department of Medical Microbiology and Parasitology Faculty of Medicine and Health Sciences Universiti Putra Malaysia Muthayammal Centre for Advanced Research Muthayammal College of Arts and Science Scigen Research and Innovation Pvt. Ltd. Periyar Technology Business Incubator

Objective: To identify the bioactive extracts from Alternanthera sessilis and investigate its cytotoxicity potential against colon cancer cells, HT-29. Methods: This study examined the effects of three parts(aerial, leaf, stem) of whole plant on HT-29 colon cancer cell lines. Three different extracts from the plant parts were prepared by maceration technique using 80% ethanol. The anticancer activities were determined using MTT, clonogenic, cell motility and AOPI assay. The chemical composition profiling was analyzed by GC-MS. Results: Among three plant part extracts, leaf extract greatly suppressed the growth of colon cancer cells in time and dosage-dependent manner, followed by aerial and stem. The cytotoxicity results were rationalized with clonogenic, cell motility and AO/PI assay, where extract showed the most active activity compared to aerial and stem extracts. GC-MS analysis of leaf extract showed there were various recognized anti-cancer, anti-oxidant and anti-inflammatory compounds. Conclusions: Amid the screened extracts, the leaf extract exhibits the credible cytotoxic, anti-proliferative and apoptotic activity and hence, our findings call for additional research to conclude the active compounds and their mechanisms determining the apoptotic activity.

关键词： Alternanthera sessilis Colorectal cancer Anticancer HT-29 Apoptosis

Primary tuberculous appendicitis presented with caecal perforation:A case report

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Asian Pacific Journal of Tropical Medicine 2012年第10期5卷 834-836页

作者： Elamurugan TP Sivashanker M suresh kumar S Muthukumarassamy R Vikram Kate Department and Institution/Department of surgery Jawaharlal Institute of Postgraduate Medical Education and Research(JIPMER)PuducherryIndia

Gastrointestinal tuberculosis accounts for 3%of the extrapulmonary tuberculosis with ileocaecal region being the common site of involvement up to 75%.Primary involvement of appendix is very rare and accounts for only 0.6%to 2.9%of gastrointestinal tuberculosis in the absence tubercular focus *** pre-operative investigations usually give non-specific results. The diagnosis in most instances made only after *** we report a case of primary appendicular tuberculosis in a patient presented with caecal perforation.

关键词： Appendicular tuberculosis Intestinal tuberculosis Caecal peroration TB Abdomen

Novel potential for optimization of antitubercular therapy:Pulmonary delivery of rifampicin lipospheres

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Asian Journal of Pharmaceutical Sciences 2015年第6期10卷 549-562页

作者： Charan Singh L.V.Seshu kumar Koduri Arti Singh Sarasija suresh Department of Pharmaceutical Technology(Formulations) National Institute of Pharmaceutical Education and Research(NIPER)Sector 67S.A.S.Nagar(Mohali)Punjab 160062India Pharmacology Division University Institute of Pharmaceutical SciencesPanjab UniversityChandigarh 160014India Presently at Faculty of Pharmacy MSRUASBangalore-560057India.Peer review under responsibility of Shenyang Pharmaceutical University

The aim of the present work is to develop rifampicin loaded phospholipid lipospheres containing sulfphobutyl etherβ-cyclodextrin and Vitamin C for inhalation to test their potential for deep lung *** findings of the solid state characterization revealed the amorphous nature of the *** exhibited a better flowability,an aerodynamic diameter in the range of 1.76 to 3.99μ***,the fine particle fraction and emitted dose was found in the range of 68.84–83.73% and 80–93%,***,lipospheres exhibited enhanced/equivalent efficacy in vitro in H37Rv ***,the results show the potential of lipospheres for pulmonary delivery of rifampicin.

关键词： Rifampicin Phospholipid Cyclodextrin Vitamin C Inhalation Lipospheres

A Resource Management Algorithm for Virtual Machine Migration in Vehicular Cloud Computing

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Computers, Materials & Continua 2021年第5期67卷 2647-2663页

作者： Sohan kumar Pande Sanjaya kumar Panda Satyabrata Das Kshira Sagar sahoo Ashish Kr.Luhach N.Z.Jhanjhi Roobaea Alroobaea Sivakumar Sivanesan Veer Surendra Sai University of Technology Burla Burla768018India National Institute of Technology Warangal Warangal506004India VNR Vignana Jyothi Institute of Engineering and Technology Hyderabad500090India The Papua New Guinea University of Technology Lae-41PapuaNew Guinea School of Computer Science and Engineering Taylor’s UniversitySubang Jaya47500Malaysia Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia

In recent years,vehicular cloud computing(VCC)has gained vast attention for providing a variety of services by creating virtual machines(VMs).These VMs use the resources that are present in modern smart *** studies reported that some of these VMs hosted on the vehicles are overloaded,whereas others are *** a circumstance,the energy consumption of overloaded vehicles is drastically *** the other hand,underloaded vehicles are also drawing considerable energy in the underutilized ***,minimizing the energy consumption of the VMs that are hosted by both overloaded and underloaded is a challenging issue in the VCC *** proper and efcient utilization of the vehicle’s resources can reduce energy consumption *** of the solutions is to improve the resource utilization of underloaded vehicles by migrating the over-utilized VMs of overloaded *** the other hand,a large number of VM migrations can lead to wastage of energy and time,which ultimately degrades the performance of the *** paper addresses the issues mentioned above by introducing a resource management algorithm,called resource utilization-aware VM migration(RU-VMM)algorithm,to distribute the loads among the overloaded and underloaded vehicles,such that energy consumption is ***-VMM monitors the trend of resource utilization to select the source and destination vehicles within a predetermined threshold for the process of VM *** ensures that any vehicles’resource utilization should not exceed the threshold before or after the ***-VMM also tries to avoid unnecessary VM migrations between the ***-VMM is extensively simulated and tested using nine *** results are carried out using three performance metrics,namely number of nal source vehicles(nfsv),percentage of successful VM migrations(psvmm)and percentage of dropped VM migrations(pdvmm),and compared with threshold-based algorithm(i.e.,threshold)and

关键词： Resource management virtual machine migration vehicular cloud computing resource utilization source vehicle destination vehicle

Metathesis synthesis, characterization, spectral and photoactivity studies of Ln_(2/3)MoO_4(Ln=La, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Er and Y)

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Journal of Rare Earths 2015年第8期33卷 837-845页

作者： Radha Velchuri suresh Palla G.Ravi Naveen kumar Veldurthi J.R.Reddy M.Vithal Department of Chemistry Osmania University

Rare earth ortho-oxomolybdates of composition Ln2/aMoO4 （Ln=La, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Er and Y） were prepared by metathesis reaction. All these materials were characterized by powder X-ray diffraction, Fourier transform-infrared spectroscopy （FT-IR） and UV-Vis diffuse reflectance spectra. The Rietveld analysis of all the samples was carried out to obtain the unit cell parameters and reliability factors. All the materials were crystallized in tetragonal lattice with I41/a space group. The infrared spectra of all the samples were characterized by bands due to MoO42 units. The bandgap energies of all the samples were obtained from UV-Vis DRS spectra. The luminescence spectra of Ln2/3MoO4 （Ln=Pr, Eu and Dy） showed characteristic transitions of the rare earth ions. The visible light photocatalytic activity of all the samples was studied against degradation of methylene blue.

关键词： metathesis X-ray diffxaction IR spectroscopy UV-Vis spectroscopy photodegradation rare earths

Text Extraction and Enhancement of Binary Images Using Cellular Automata

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International Journal of Automation and computing 2009年第3期6卷 254-260页

作者： G. sahoo Tapas kumar B. L. Raina C. M. Bhatia Department of Information Technology Birla Institute of Technology Department of Information Technology Lingaya s University Department of Electrical Engineering Indian Institute of Technology

Text characters embedded in images represent a rich source of information for content-based indexing and retrieval applications. However, these text characters are difficult to be detected and recognized due to their various sizes, grayscale values, and complex backgrounds. Existing methods cannot handle well those texts with different contrast or embedded in a complex image background. In this paper, a set of sequential algorithms for text extraction and enhancement of image using cellular automata are proposed. The image enhancement includes gray level, contrast manipulation, edge detection, and filtering. First, it applies edge detection and uses a threshold to filter out for low-contrast text and simplify complex background of high-contrast text from binary image. The proposed algorithm is simple and easy to use and requires only a sample texture binary image as an input. It generates textures with perceived quality, better than those proposed by earlier published techniques. The performance of our method is demonstrated by presenting experimental results for a set of text based binary images. The quality of thresholding is assessed using the precision and recall analysis of the resultant text in the binary image.

关键词： Text extraction edge detection cellular automata algorithm text detection thresholding.

In vitro antioxidant assessment and a rapid HPTLC bioautographic method for the detection of anticholinesterase inhibitory activity of Geophila repens

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Journal of Integrative Medicine 2017年第3期15卷 231-241页

作者： Umesh Chandra Dash Atish kumar sahoo Regional Plant Resource Centre Medicinal & Aromatic Plant Division Forest & Environment DepartmentGovt. of Odisha Nayapalli Bhubaneswar 751015 India

OBJECTIVE： Geophila repens （L.） I. M. Johnst. （Rubiaceae）, a small, creeping, perennial herb, is claimed to have memory-enhancing property. The goal of this study was to assess its antioxidant and anticholinesterase activity and conduct a rapid bioautographic enzyme assay for screening acetylcholinesterase （ACHE） and butyrylcholinesterase （BChE） inhibition of G. repens extracts. METHODS： Antioxidant activity of G. repens extracts was assessed by performing 1,1-diphenyl-2- picrylhydrazyl （DPPH）, nitric oxide （NO）, superoxide （SOD）, hydroxyl （OH） and total antioxidant capacity （TAC） assays. Anticholinesterase activity was investigated by quantifying the AChE and BChE inhibitory activities of chloroform （CGR）, ethyl acetate （EGR） and methanol （MGR） extract fractions from G. repens leaves. A rapid high-performance thin-layer chromatography （HPTLC） bioautographic method for the detection of AChE and BChE inhibition was performed. RESULTS： Among all extract fractions, EGR exhibited the highest half maximal inhibitory concentration （IC50） in DPPH, SOD, NO, OH and TAC assays, with IC50 of （38.33 ± 3.21）, （45.14 ±1.78）, （59.81± 1.32）, （39.45 ± 0.79） and （43.76 ± 0.81 ） μg/mL respectively. EGR displayed competitive, reversible inhibition of AChE and BChE activities with IC50 of （68.63±0.45） and （59.45 ±0.45）μg/mL, respectively. Total phenolic and flavonoids contents of EGR were found to be 360.42 mg gallic acid equivalents and 257.31 mg quercetin equivalents per gram of extract. Phytoconstituents of the EGR extract that were inhibitors of cholinesterase produced white spots on the yellow background of HPTLC plates in the bioautographic test. CONCLUSION： The results of this study revealed that phenols and flavonoids could be responsible for the antioxidant, anticholinesterase activities of G. repens.

关键词： Geophila repens Alzheimer disease acetylcholinesterase butyrylcholinesterase fingerprint bioautographic phenolic, antioxidant

Rapid separation of acetophenone and its monohydroxy isomers by capillary electrophoresis

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Chinese Chemical Letters 2013年第9期24卷 833-836页

作者： Ramaiyan Sekar suresh kumar Kailasa Wen-Shan Li Han-Chung Wu Hui-Fen Wu Department of Chemistry National Sun Yat-Sen University Depatment of Applied Chemistry S.V. National Institute of Technology Doctoral Degree Program in Marine Biotechnology National Sun Yat-Sen University Institute of Chemistry Academia Sinica Institute of Cellular and Organismic Biology Academia Sinica Center of Nanoscience and Nanotechnology National Sun Yat-Sen University School of Pharmacy College of Pharmacy Kaohsiung Medical University

This work describes the development of a capillary electrophoresis （CE） method for the simultaneous separation of acetophenone （AP）, 2-hydroxyacetophenone （2-HAP）, 3-hydroxyacetophenone （3-HAP） and 4-hydroxyacetophenone （4-HAP） in synthetic mixtures using 10 mmol/L of sodium tetraborate buffer （pH 9.5）. The aim of this work is to demonstrate the effectiveness of CE to separate AP and its monohydroxy isomers and to define how the separations are affected by buffers, buffer pH, sample matrices and separation voltage. This method was successfully used for the trace level separation and determination of 2-HAP, 3-HAP and 4-HAP in synthetic mixture and 4-HAP in spiked plasma samples.

关键词： Capillary electrophoresis Electrokinetic injection Acetophenone isomers Plasma

Screening and antibacterial efficacy of selected Indian medicinal plants

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Asian Pacific Journal of Tropical Biomedicine 2016年第3期6卷 185-191页

作者： suresh Mickymaray Mohammad Saleh Al Aboody Pradipta kumar Rath Panneerselvam Annamalai Thajuddin Nooruddin Department of Medical Laboratories College of Science Al-Zulfi Majmaah University Department of Diagnostic Microbiology and Molecular Biology Doctors' Diagnostic Centre Post Graduate & Research Department of Botany & Microbiology A. Veeriya Vandayar Memorial Sri Pushpam College(Autonomous) Department of Microbiology School of Life Sciences Bharathidasan University

Objective: To evaluate the antibacterial efficacy of five Indian medicinal plants such as Acalypha indica L.(A. indica), Aerva lanata(L.) Juss. ex Schult.(A. lanata), Clerodendrum inerme(L.) Gaertn., Pergularia daemia(Forsk.) Chiov. and Solanum surattense Burm. f. against opportunistic bacterial pathogens isolated from HIV infected patients for the potential phytoconstituents in plant ***: The opportunistic bacterial pathogens such as Escherichia coli(E. coli),Pseudomonas aeruginosa, Salmonella typhi and Serratia marcescens from Gramnegative group and Staphylococcus aureus from Gram-positive group were isolated from HIV infected patients. The antibacterial efficacy of ethanolic extracts of selected medicinal plants was carried out by disc diffusion method. The potential phytoconstituents of medicinal plant extracts were identified by gas chromatography and mass spectrometry(GC–MS) ***: Among the five medicinal plants tested, A. indica and A. lanata showed the significant antibacterial activity. A. indica showed potential activity against Staphylococcus aureus and E. coli. A. lanata significantly exhibited antibacterial activity against E. coli, Salmonella typhi and Pseudomonas aeruginosa. A total of 19 phytoconstituents were identified in the ethanolic extract of A. indica and A. lanata by GC–MS analysis ***: The results of the present investigation revealed that A. indica and A. lanata, possessed significant antibacterial activity when compared with the other plant extracts tested. The presence of 3-O-methyl-D-glucose by GC–MS analysis in both A. indica and A. lanata extracts has not been reported elsewhere in the literature and the findings in this study could be the first one to report.

关键词： Antibacterial efficacy Medicinal plants Bacterial pathogens Phytoconstituents