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Echocardiographic predictors and associated outcomes of multiple vegetations in infective endocarditis:A pilot study

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World Journal of Cardiology 2024年第6期16卷 318-328页

作者： Ajay kumar Mishra Kannu bansal Ibragim Al-Seykal Pradnya B Bhattad Anu Anna George Anil Jha Nitish Sharma Jennifer Sargent Mark J Kranis Division of Cardiology Saint Vincent HospitalWorcesterMA 01608United States Department of Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States Department of Medicine Division of CardiologySaint Vincent HospitalWorcesterMA 01608United States Division of Cardiovascular Medicine Saint Vincent HospitalWorcesterMA 01608United States

BACKGROUND Infective endocarditis(IE)is a life-threatening infection with an annual mortality of 40%.Embolic events reported in up to 80%of *** of>10 mm size are associated with increased embolic events and poor *** is a paucity of literature on the association of multiple vegetations with *** To study the echocardiographic(ECHO)features and outcomes associated with the presence of multiple *** In this retrospective,single-center,cohort study patients diagnosed with IE were recruited from June 2017 to June 2019.A total of 84 patients were diagnosed to have IE,of whom 67 with vegetation were *** demographic,clinical,laboratory,and ECHO parameters were *** that were studied included recurrent admission,embolic phenomenon,and *** Twenty-three(34%)patients were noted to have multiple vegetations,13(56.5%)were male and 10(43.5%)were *** mean age of these patients was ***(35%)had a prior episode of *** features of moderate to severe valvular regurgitation[odds ratio(OR)=4],presence of pacemaker lead(OR=4.8),impaired left ventricle(LV)relaxation(OR=4),and elevated pulmonary artery systolic pressure(PASP)(OR=2.2)are associated with higher odds of multiple *** these moderate to severe valvular regurgitation(P=0.028),pacemaker lead(P=0.039)and impaired relaxation(P=0.028)were statistically *** patients were noted to have an increased association of recurrent admissions(OR=3.6),recurrent bacteremia(OR=2.4),embolic phenomenon(OR=2.5),intensive care unit stay(OR=2.8),hypotension(OR=2.1),surgical intervention(OR=2.8)and device removal(OR=4.8).Of this device removal(P=0.039)and recurrent admissions(P=0.017)were statistically *** This study highlights the associations of ECHO predictors and outcomes in patients with IE having multiple *** features of moderate to severe regurgitation,presence of pacemaker lead,impai

关键词： Endocarditis Echocardiography Vegetations Predictors Outcome

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Paradigm shift in transfusion practices during early COVID-19 pandemic:A single center retrospective study

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World Journal of Virology 2024年第2期13卷 78-86页

作者： Sumukh Arun kumar Sushmita Prabhu Ankushi Sanghvi Maya Gogtay Mithil Gowda suresh Harshit Khosla Yuvaraj Singh Ajay kumar Mishra Susan George Department of Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States Department of Hematology and Oncology University of Nebraska Medical CenterOmahaNE 68198United States Hospice and Palliative Care UTHSC and McGovern School of MedicineTexasTX 77030United States Department of Gastroenterology and Hepatology UMass Chan Medical SchoolWorcesterMA 01655United States Division of Cardiology Saint Vincent HospitalWorcesterMA 01608United States

BACKGROUND The advent of coronavirus disease 2019(COVID-19)unveiled the worst national blood crisis that the United States had witnessed in over a *** the pandemic influencing the different stages of the acquisition of blood products outside the hospital setting,we aimed to explore the possible barriers contributing to the shortage of blood products within the medical *** COVID era and pre-COVID *** We conducted a retrospective cross-sectional study on hospitalized patients distinguishing the pattern of blood transfusion during the COVID and pre-COVID era in a community *** was tabulated to include the number of red blood cell(RBC)transfusions and if transfusions met restrictive blood transfusion criteria as per institutional ***-square was applied to test the statistical association between qualitative *** t test and Mann Whitney U test were applied respectively to test the mean difference of quantitative *** A total of 208 patients were included in the study,of which 108 were during COVID era and 100 were during pre-COVID *** leading reason for admission in both the COVID era and pre-COVID era transfused patients was shortness of breath(53.7%and 36%P=0.001),followed by gastrointestinal bleeding(25.9%and 21%P=0.001).There was a higher percentage of RBC transfusions in the intensive care unit in the COVID-era group than in the pre-COVID era group(38.9%vs 22%,P=0.008).The restrictive transfusion criteria were met in 62%vs 79%in the COVID and pre-COVID eras,respectively(P=0.008).CONCLUSION The COVID-era group received RBC transfusions with less stringent adherence to restrictive blood transfusion practices in comparison to pre-COVID era group.

关键词： Blood transfusion Restrictive transfusion COVID-19 Pre-COVID-19 Blood shortage Pandemic

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Performance validation of High Mountain Asia 8-meter Digital Elevation Model using ICESat-2 geolocated photons

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Journal of Mountain Science 2024年第8期21卷 2562-2578页

作者： Giribabu DANDABATHULA Subham ROY Omkar Shashikant GHATAGE Vaibhav Balaso KOLASE Shwetambari SATPUTE Koushik GHOSH Sahibnoor KAUR Satyanarayana PONDARI Apurba kumar BERA Sushil kumar SRIVASTAV Regional Remote Sensing Centre-West National Remote Sensing CentreIndian Space Research OrganisationJodhpur 342005India Department of Geography School of Earth SciencesBharathidasan UniversityTiruchirappalli 620024India Centre for Climate Change and Water Research Suresh Gyan Vihar UniversityJaipur 302017India Department of Geography Panjab UniversityChandigarh 160014India National Remote Sensing Centre Indian Space Research OrganisationHyderabad 500037India Regional Centres National Remote Sensing CentreIndian Space Research OrganisationNew Delhi 110049India

High Mountain Asia(HMA),recognized as a third pole,needs regular and intense studies as it is susceptible to climate *** accurate and high-resolution Digital Elevation Model(DEM)for this region enables us to analyze it in a 3D environment and understand its intricate role as the Water Tower of *** science teams of NASA realized an 8-m DEM using satellite stereo imagery for HMA,termed HMA 8-m *** this research,we assessed the vertical accuracy of HMA 8-m DEM using reference elevations from ICESat-2 geolocated photons at three test sites of varied topography and land *** were made from statistical quantifiers and elevation *** the world’s highest mountain,Mount Everest,and its surroundings,Root Mean Squared Error(RMSE)and Mean Absolute Error(MAE)resulted in 1.94 m and 1.66 m,respectively;however,a uniform positive bias observed in the elevation profiles indicates the seasonal snow cover change will dent the accurate estimation of the elevation in this sort of test *** second test site containing gentle slopes with forest patches has exhibited the Digital Surface Model(DSM)features with RMSE and MAE of 0.58 m and 0.52 m,*** third test site,situated in the Zanda County of the Qinghai-Tibet,is a relatively flat terrain bed,mostly bare earth with sudden river cuts,and has minimal errors with RMSE and MAE of 0.32 m and 0.29 m,respectively,and with a negligible ***,in one more test site,the feasibility of detecting the glacial lakes was tested,which resulted in exhibiting a flat surface over the surface of the lakes,indicating the potential of HMA 8-m DEM for deriving the hydrological *** results accrued in this investigation confirm that the HMA 8-m DEM has the best vertical accuracy and should be of high use for analyzing natural hazards and monitoring glacier surfaces.

关键词： High Mountain Asia Digital Elevation Model ICESat-2 geolocated photons Accuracy assessment

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Optimal PV Array Configuration for Extracting Maximum Power Under Partial Shading Conditions by Mitigating Mismatching Power Losses

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CSEE Journal of Power and Energy Systems 2022年第2期8卷 499-510页

作者： Praveen kumar Bonthagorla suresh Mikkili the Electrical and Electronics Engineering Department National Institute of Technology Goa403401India

The grid-connected or standalone PV central inverter architecture is comprised of several PV modules which are connected in different ways to form the PV *** power generation capability of the PV array is primarily affected by partial shading conditions(PSC).Due to PSCs,the power output of the PV array is dramatically reduced,and mismatching losses are induced in the PV *** on the extent of these problems,multiple peaks also appear in the power-voltage(P-V)curve,which makes it very difficult to track the global maximum power point(GMPP).The main objective of this research paper is to model and simulate the series(S),series-parallel(SP),bridge-link(BL),honey-comb(HC),total-cross-tied(TCT)and proposed triple-tied(TT)solar PV array configurations under various partial shading *** performance of all PV configurations is evaluated under a uniform approach,considering eight different shading *** performance of the considered PV configurations is analyzed in terms of their mismatching power losses,fill factors,efficiency,global maximum power points(GMPPs),local maximum power points(LMPPs),voltages and currents at GMPPs,open circuit voltage and short circuit *** above-mentioned PV configurations are modeled and simulated in a Matlab/Simulink environment by considering the KC-200GT module parameters.

关键词： Photo voltaic(PV) PV array configurations triple-tied(TT) maximum power point(MPP) partial shading mismatching power losses fill factor efficiency

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Performance Investigation of Hybrid and Conventional PV Array Configurations for Grid-connected/Standalone PV Systems

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CSEE Journal of Power and Energy Systems 2022年第3期8卷 682-695页

作者： Praveen kumar Bonthagorla suresh Mikkili Department of Electrical and Electronics Engineering National Institute of TechnologyGoaIndia

Currently,the critical challenge in solar photovoltaic(PV)systems is to make them energy *** of the key factors that can reduce the PV system power output is partial shading conditions(PSCs).The reduction in power output not only depends on a shaded region but also depends on the pattern of shading and physical position of shaded modules in the *** to PSCs,mismatch losses are induced between the shaded modules which can cause several peaks in the output power-voltage(P-V)*** series-parallel(SP),total-cross-tied(TCT),bridge-link(BL),honey-comb(HC),and triple-tied(TT)configurations are considered as conventional configurations,which are severely affected by PSCs and generate more mismatch power losses along with a greater number of local *** reduce the effect of PSCs,hybrid PV array configurations,such as series-parallel:total-cross-tied(SP-TCT),bridge-link:total-cross-tied(BL-TCT),honey-comb:total-cross-tied(HC-TCT)and bridge-link:honey-comb(BL-HC)are *** paper briefly discusses the modeling,simulation and performance evaluation of hybrid and conventional 7×7 PV array configurations during different PSCs in a Matlab/Simulink *** performance of hybrid and conventional PV configurations are evaluated and compared in terms of global maximum power(GMP),voltage and currents at GMP,open and short circuit voltage and currents,mismatch power loss(MPL),fill factor,efficiency,and a number of local maximum power peaks(LMPPs).

关键词： Fill factor global maximum power(GMP) hybrid PV array configuration maximum power point(MPP) mismatch power loss(MPL) partial shading triple-tied(TT)

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Effect of heat treatment conditions on ballistic behaviour of various zones of friction stir welded magnesium alloy joints

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Transactions of Nonferrous Metals Society of China 2021年第1期31卷 156-166页

作者： S.DHARANI kumar S.suresh kumar Department of Mechanical Engineering Sri Eshwar College of EngineeringCoimbatore641202Tamil NaduIndia Department of Mechanical Engineering Sri Sivasubramaniya Nadar College of EngineeringChennai603110Tamil NaduIndia

Ballistic behaviour of different zones of post-weld heat-treated(PWHT)magnesium alloy(AZ31B)target against 7.62 mm×39 mm armour-piercing(AP)projectile with a striking velocity of(430±20)m/s was *** alloy(AZ31B)welded joints were prepared by using friction stir welding(FSW)process and subjected to different heat treatment *** microhardness values of non-heat-treated and heat-treated FSW joints were *** results indicated that PWHT process(250°C,1 h)has improved the microhardness of heat-treated FSW *** electron microscope(SEM)microstructure showed that heat treatment has caused the formation of fineα-Mg grains and tiny precipitates and made the dissolution ofβ-Mg17Al12 phase into the Mg *** ballistic behaviour of PWHT zones was estimated by measuring the depth of penetration(DOP)of the *** DOP value was observed for the base metal zone(BMZ)of a heat-treated welded *** ballistic SEM examinations on the cross-section of all three zones of crater region showed the formation of adiabatic shear band(ASB).

关键词： AZ31B magnesium alloy post-weld heat treatment ballistic behaviour penetration depth adiabatic shear band

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Gastroprotective effect of Acacia nilotica young seedless pod extract:Role of polyphenolic constituents

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Asian Pacific Journal of Tropical Medicine 2012年第7期5卷 523-528页

作者： Vijay kumar bansal Rajesh kumar Goel Department of Pharmaceutical Sciences NIMS UniversityJaipurIndia Department of Pharmaceutical Sciences and Drug Research Punjabi University PatialaIndia

Objective:To systematically evaluate antiulcer potential of Acacia nilotica in different ulcer models in ***:Different extracts[ethanolie,50%hydroethanolic(50:50),70% hydroethanolic(70:30) and aqueous]of young seedless pods were examined in pylorus ligation induced gastric ulcers in *** parameters like,volume of gastric acid secretion,pH,free acidity,total acidity,ulcer index,mucin content and antioxidant studies were determined and were compared between extract treated,standard and vehicle control following ulcer induction. The most active extract was also evaluated in swimming stress induced and NSAID induced gastric ***:Among different extracts of young seedless pods only hydroethanolic extracts showed significant antiulcer activity in pyloric ligation induced *** more the 70%hydroethanolic extract showed better protection as compared to 50%hydroethanolic *** 70%hydroethanolic extract also showed significant mucoprotection in swimming stress induced and nonsteroidal antiinflammatory drugs induced gastric ***: The results of present study concluded that the hydroethanolic extract of young seedless pods of Acacia nilotica has antiulcer activity in pylorus ligation,swimming stress and NSAID induced rat ulcer *** extract containing more amount of phenolic components show high antiulcer activity,indicating the phenolic component of the extract to be responsible for the activity of the extracts.

关键词： Peptic ulcer Acacia nilotica Ulcer index Tannins Flavonoids

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A methodological approach for weighting factors in land suitability assessment: a tool for facilitating spatial planning

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Journal of Mountain Science 2020年第3期17卷 724-739页

作者： Neetu KAPOOR Minakshi JAIN Vijay kumar bansal Department of Architecture National Institute of Technology HamirpurHP 177005India School of Planning and Architecture VijayawadaAP 520008India Department of Civil Engineering National Institute of Technology HamirpurHP 177005India

The increasing demand for infrastructural facilities in hill areas needs efficient spatial planning at the local level through land suitability assessment,which is influenced by a number of factors. There has been little systematic empirical work for identification and evaluation of the factors affecting spatial planning decisions in hill areas. The present study focuses on identifying the critical factors for land suitability assessment at the local level in hill areas and determining their percentage influence, which has been done in two stages. In the first stage, the comprehensive list of 21 factors from the reported literature was prepared which was further condensed to the critical factors. In the second stage, the percentage influence of the critical factors was calculated by analyzing the experts’ opinions collected through a questionnaire survey. Analytic Hierarchy Process(AHP) was used for the analysis of the questionnaire for weighting the critical factors. The slope was identified with the highest weight followed by aspect, surface runoff, elevation, and vegetation,whereas groundwater table, existing utilities,accessibility, soil type, and land use have comparatively less weights. The results of the study were used for the identification of locations for builtup facilities of an educational campus located in hill areas of Himachal Pradesh, India.

关键词： Factor identification Hill areas Analytic hierarchy process India Weighted overlay

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Anticoagulant use before COVID-19 diagnosis prevent COVID-19 associated acute venous thromboembolism or not:A systematic review and meta-analysis

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World Journal of Methodology 2024年第3期14卷 141-162页

作者： Kinza Iqbal Akshat Banga Taha Bin Arif Sawai Singh Rathore Abhishek Bhurwal Syeda Kisa Batool Naqvi Muhammad Mehdi Pankaj kumar Mitali Madhu Salklan Ayman Iqbal Jawad Ahmed Nikhil Sharma Amos Lal Rahul Kashyap Vikas bansal Juan Pablo Domecq Department of Internal Medicine Dow Medical CollegeKarachi 74200Pakistan Department of Internal Medicine Sawai Man Singh Medical CollegeJaipur 302004India Department of Internal Medicine Dr.Sampurnanand Medical CollegeJodhpur 342003RajasthanIndia Department of Gastroenterology and Hepatology Rutgers Robert Wood Johnson School of MedicineNew BrunswickNJ 08901United States Department of Internal Medicine Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical SciencesRohtak 124001HaryanaIndia Department of Nephrology and Hypertension Mayo ClinicRochesterMN 55905United States Department of Medicine Division of Pulmonary and Critical Care MedicineMayo ClinicRochesterMN 55905United States Department of Research Wellspan HealthYorkPA 17403United States

BACKGROUND Coagulopathy and thromboembolic events are associated with poor outcomes in coronavirus disease 2019(COVID-19)*** is conflicting evidence on the effects of chronic anticoagulation on mortality and severity of COVID-19 *** To summarize the body of evidence on the effects of pre-hospital anticoagulation on outcomes in COVID-19 *** A Literature search was performed on LitCovid PubMed,WHO,and Scopus databases from inception(December 2019)till June 2023 for original studies reporting an association between prior use of anticoagulants and patient outcomes in adults with *** primary outcome was the risk of thromboembolic events in COVID-19 patients taking *** outcomes included COVID-19 disease severity,in terms of intensive care unit admission or invasive mechanical ventilation/intubation requirement in patients hospitalized with COVID-19 infection,and *** random effects models were used to calculate crude and adjusted odds ratios(aORs)with 95%confidence intervals(95%CIs).RESULTS Forty-six observational studies met our inclusion *** unadjusted analysis found no association between prior anticoagulation and thromboembolic event risk[n=43851,9 studies,odds ratio(OR)=0.67(0.22,2.07);P=0.49;I2=95%].The association between prior anticoagulation and disease severity was non-significant[n=186782;22 studies,OR=1.08(0.78,1.49);P=0.64;I2=89%].However,pre-hospital anticoagulation significantly increased all-cause mortality risk[n=207292;35 studies,OR=1.72(1.37,2.17);P<0.00001;I2=93%].Pooling adjusted estimates revealed a statistically non-significant association between pre-hospital anticoagulation and thromboembolic event risk[aOR=0.87(0.42,1.80);P=0.71],mortality[aOR=0.94(0.84,1.05);P=0.31],and disease severity[aOR=0.96(0.72,1.26);P=0.76].CONCLUSION Prehospital anticoagulation was not significantly associated with reduced risk of thromboembolic events,improved survival,and lower disease seve

关键词： Prior anticoagulation COVID-19 Prehospital anticoagulation Chronic anticoagulation Mortality Severity Thromboembolic events

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Hybrid, Optimal, Intelligent and Classical PV MPPT Techniques: A Review

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CSEE Journal of Power and Energy Systems 2021年第1期7卷 9-33页

作者： Ratnakar Babu Bollipo suresh Mikkili Praveen kumar Bonthagorla Department of Electrical and Electronics Engineering National Institute of Technology GoaFARMAGUDIPondaGoa 403401India

Renewable energy-based solar photovoltaic(PV)generation is the best alternative for conventional energy sources because of its natural abundance and environment friendly *** power extraction from the PV system plays a critical role in increasing the efficiency of the solar power generation during partial shading conditions(PSCs).Therefore,a suitable maximum power point tracking(MPPT)technique to track the maximum power point(MPP)is of high need,even under *** paper presents an organized and concise review of MPPT techniques implemented for the PV systems in literature along with recent publications on various hardware design *** classification is done into four categories,***,intelligent,optimal,and hybrid depending on the tracking algorithm utilized to track MPP under *** uniform insolation,classical methods are highly preferred as there is only one peak in the P-V ***,under PSCs,the F-V curve exhibits multiple peaks,one global maximum power point(GMPP)and remaining are local maximum power points(LMPP’s).Under the PSCs,classical methods fail to operate at GMPP and hence there is a need for more advanced MPPT *** MPPT technique has its advantages and limits,but a streamlined MPPT is drafted in numerous parameters like sensors required,hardware implementation,cost viability,tracking speed and tracking *** study provides the advancement in this area since some parameter comparison is made at the end of every classification,which might be a prominent base-rule for picking the most gainful sort of MPPT for further research.

关键词： GMPP MPPT classification MPPT techniques partial shading conditions(PSCs) photovoltaic system

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