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Paradigm shift in transfusion practices during early COVID-19 pandemic:A single center retrospective study

World Journal of Virology 2024年第2期13卷 78-86页

作者： Sumukh Arun Kumar Sushmita prabhu Ankushi Sanghvi Maya Gogtay Mithil Gowda suresh Harshit Khosla Yuvaraj Singh Ajay Kumar Mishra Susan George Department of Internal Medicine Saint Vincent HospitalWorcesterMA 01608United States Department of Hematology and Oncology University of Nebraska Medical CenterOmahaNE 68198United States Hospice and Palliative Care UTHSC and McGovern School of MedicineTexasTX 77030United States Department of Gastroenterology and Hepatology UMass Chan Medical SchoolWorcesterMA 01655United States Division of Cardiology Saint Vincent HospitalWorcesterMA 01608United States

BACKGROUND The advent of coronavirus disease 2019(COVID-19)unveiled the worst national blood crisis that the United States had witnessed in over a *** the pandemic influencing the different stages of the acquisition of blood products outside the hospital setting,we aimed to explore the possible barriers contributing to the shortage of blood products within the medical *** COVID era and pre-COVID *** We conducted a retrospective cross-sectional study on hospitalized patients distinguishing the pattern of blood transfusion during the COVID and pre-COVID era in a community *** was tabulated to include the number of red blood cell(RBC)transfusions and if transfusions met restrictive blood transfusion criteria as per institutional ***-square was applied to test the statistical association between qualitative *** t test and Mann Whitney U test were applied respectively to test the mean difference of quantitative *** A total of 208 patients were included in the study,of which 108 were during COVID era and 100 were during pre-COVID *** leading reason for admission in both the COVID era and pre-COVID era transfused patients was shortness of breath(53.7%and 36%P=0.001),followed by gastrointestinal bleeding(25.9%and 21%P=0.001).There was a higher percentage of RBC transfusions in the intensive care unit in the COVID-era group than in the pre-COVID era group(38.9%vs 22%,P=0.008).The restrictive transfusion criteria were met in 62%vs 79%in the COVID and pre-COVID eras,respectively(P=0.008).CONCLUSION The COVID-era group received RBC transfusions with less stringent adherence to restrictive blood transfusion practices in comparison to pre-COVID era group.

关键词： Blood transfusion Restrictive transfusion COVID-19 Pre-COVID-19 Blood shortage Pandemic

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Factors Associated with Poor Sleep Quality among Type 2 Diabetes Mellitus Patients on Insulin Therapy

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Journal of Diabetes Mellitus 2015年第4期5卷 206-210页

作者： Abilash Sathyanarayanan Elvin Benny Jenit Osborn Senthil Kumar suresh prabhu Anil C. Mathew PSG Institute of Medical Sciences and Research Coimbatore India Department of Statistics St. Thomas College Pala India Department of Community Medicine PSG Institute of Medical Sciences and Research Coimbatore India Department of Endocrinology PSG Institute of Medical Sciences and Research Coimbatore India

The aim of this study is to investigate the possible risk factors of poor sleep quality among patients with type 2 diabetes mellitus on insulin therapy. The factors considered were age, sex, body mass index (BMI), glycosylated haemoglobin (HbA1c), duration of diabetes and depression. A total of 202 diabetic patients aged 20 years or older were included in the study. The results showed that female sex and depression were independent risk factors for poor sleep quality among type 2 diabetics on insulin therapy. Findings may contribute to sleep disorder control in female patients with type 2 diabetes mellitus which has been linked to glycemic control.

关键词： Diabetes Sleep Quality Insulin Administration Depression

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Test re-test reliability of virtual acoustic space identification (VASI) test in young adults with normal hearing

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Journal of Otology 2023年第1期18卷 55-62页

作者： Kavassery Venkateswaran Nisha Prabuddha Bhatarai Kruthika suresh Shashish Ghimire Prashanth prabhu Department of Audiology All India Institute of Speech and HearingManasagangothriMysuru570006India

Background:Recent developments in virtual acoustic technology has levered promising applications in the field of auditory sciences,especially in spatial *** conventional auditory spatial assessment using loudspeakers,interaural differences and/or questionnaires are limited by the availability and cost of instruments,the use of virtual acoustic space identification(VASI)test has widespread applications in spatial test battery as it overcomes these ***:The lack of test-retest reliability data of VASI test narrows its direct application in auditory spatial assessment,which is explored in the present ***:Data from 75 normal-hearing young adults(mean age:25.11 y±4.65 SD)was collected in three sessions:baseline,within 15 min of baseline(intra-session),and one week after baseline session(inter-session).Test-retest reliability was assessed using the intra-class correlation coefficient(ICC),coefficient of variation(CV),and cluster ***:The results showed excellent reliability for both accuracy and reaction time measures of VASI,with ICC values of 0.93 and 0.87,*** CV values for overall VASI accuracy and reaction time 9.66% and 11.88%,*** was also complemented by the cluster plot analyses,which showed 93.33% and 96.00% of temporal stability in the accuracy and reaction time measures,indicative of high test-retest reliability of VASI test in auditory spatial ***:The high temporal stability(test-retest reliability)of VASI test validates its application in spatial hearing test battery.

关键词： Test-retest reliability Psychoacoustics Virtual auditory spatial perception Intra-and inter-session Accuracy Reaction time

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