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Dietary eubiotics of microbial muramidase and glycan improve intestinal villi,ileum microbiota composition and production trait of broiler

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Journal of Animal Science and Biotechnology 2024年第4期15卷 1723-1736页

作者： Sungbo Cho Shanmugam suresh kumar Santiago Ramirez Rolando Valientes In Ho Kim Department of Animal Resource and Science Dankook UniversityCheonanChungnam 31116Korea Smart Animal Bio Institute Dankook University CheonanKorea DSM Nutritional Products Asia Pacific Mapletree Business CitySingapore 117440Singapore

Background Optimal gut health is important to maximize growth performance and feed efficiency in broiler chickens.A total of 1,365 one-day-old male Ross 308 broiler chickens were randomly divided into 5 treatments groups with 21 replicates,13 birds per *** present research investigated effects of microbial muramidase or a precision glycan alone or in combination on growth performance,apparent total tract digestibility,total blood carotenoid content,intestinal villus length,meat quality and gut microbiota in broiler *** included:NC:negative control(basal diet group);PC:positive control(basal diet+0.02%probiotics);MR:basal diet+0.035%microbial muramidase;PG:basal diet+0.1%precision glycan;and MRPG:basal diet+0.025%MR+0.1%PG,*** MRPG group increased the body weight gain and feed intake(P<0.05)compared with NC ***,it significantly increased total serum carotenoid(P<0.05)and MRPG altered the microbial diversity in ileum *** MRPG treatment group increased the abundance of the phylum Firmicutes,and family Lachnospiraceae,Ruminococcaceae,Oscillospiraceae,Lactobacillaceae,Peptostreptococcaceae and decreased the abundance of the phylum Campilobacterota,Bacteroidota and family *** with the NC group,the chickens fed MRPG showed significantly increased in duodenum villus length at end the *** In this study,overall results showed that the synergetic effects of MR and PG showed enhancing growth performance,total serum carotenoid level and altering gut microbiota composition of *** current research indicates that co-supplementation of MR and PG in broiler diets enhances intestinal health,consequently leading to an increased broiler production.

关键词： Broiler Intestinal morphology Microbial muramidase Precision glycan Probiotics

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Palaeodepositional environment,implications of Glossopteris flora,and organic matter characteristics from the Lower Permian,Karo Open Cast Mine,East Bokaro Coalfield,Damodar Basin,India

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Journal of Palaeogeography 2024年第3期13卷 528-546页

作者： Sankar suresh kumar Pillai Rose Ann Sebastian Runcie Paul Mathews Srikanta Murthy Anju Saxena Mrutyunjaya Sahoo Suraj kumar Sahu Gulshan kumar Dhingra Birbal Sahni Institute of Palaeosciences 53 University RoadLucknow-226007UPIndia Academy of Scientific and Innovative Research(AcSIR) Ghaziabad-201002India Department of Geology School of Earth Science SystemsCentral University of KeralaKasaragod-671316KeralaIndia Department of Geology Ravenshaw UniversityCuttack-753003OdishaIndia Department of Botany Sri Dev Suman Uttarakhand UniversityUttarakhand-249145India

The present study deals with the Early Permian floral diversity,palaeoenvironment,palaeoclimate and depositional setting using a multiproxy approach that includes morphotaxonomy,palynology,and organic geochemistry of Karo OCM(Open Cast Mine),East Bokaro Coalfield,Damodar Gondwana Basin,*** Permian sediments of Peninsular India are widely regarded as fluvial,along with some marine *** macroplant fossil assemblage exhibits the presence of Glossopteridales,comprising Glossopteris,Gangamopteris,and Vertebraria,as well as Coniferales,which includes *** palynological assemblage encompasses the dominance of the striate bisaccate pollen Faunipollenites *** the subdominance of the non-striate bisaccate pollen Scheuringipollenites *** glossopterid *** megafloral and palynofloral assemblage confirms the biostratigraphical age to be Late Barakar palynoflora of Kungurian *** studied morphological characteristics,including small to large Glossopteris leaves exhibiting a lanceolate shape,acute apices,and acute cuneate or tapering bases,as well as entire margins with narrower lamina and narrow meshes,suggest the existence of a dense forest with the prevalence of a warm and humid climate during their *** organic geochemical characterization based on functional group and biomarker analyses reveals the diagenetic effects on organic *** symmetric(~2865-2855 cm^(-1))and asymmetric stretching(~2930-2910 cm^(-1))peaks are identifiable in coal samples,whereas they are absent in carbonaceous *** A-factor vs.C-factor plot suggests that the kerogen type is type Ⅲ,which can generate mainly gaseous *** vitrinite reflectance studies(R_(r) av.1.1%)show increased maturity of the samples,which is supported by the n-alkane distribution pattern and the absence of hopane *** Indian floral assemblages in contemporary of southern Gondwana continents reveal a stronger inclination/affinity with th

关键词： Glossopteris Palynomorph FTIR GCMS Gondwana Permian Palaeoclimate

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Adverse events associated with the gold probe and the injection gold probe devices used for endoscopic hemostasis:A MAUDE database analysis

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World Journal of Gastrointestinal Endoscopy 2024年第1期16卷 37-43页

作者： Vishnu Charan suresh kumar Mark Aloysius Ganesh Aswath Division of Gastroenterology and Hepatology SUNY Upstate Medical UniversitySyracuseNY 13202United States

BACKGROUND Gastrointestinal(GI)bleeding accounts for over half a million admissions annually and is the most common GI diagnosis requiring hospitalization in the United *** electrocoagulation devices are used for the management of gastrointestinal *** is no data on device-related adverse events for gold probe(GP)and injection gold probe(IGP).AIM To analyze this using the Food and Drug Administration(FDA’s)Manufacturer and User Facility Device Experience(MAUDE)database from 2013 to *** We examined post-marketing surveillance data on GP and IGP from the FDA MAUDE database to report devicerelated and patient-related adverse events between *** MAUDE database is a publicly available resource providing over 4 million records relating to medical device *** analyses were performed using IBM SPSS Statistics V.27.0(IBM Corp.,Armonk,NY,United States).RESULTS Our search elicited 140 reports for GP and 202 reports for IGP,respec-tively,during the study period from January 2013 to August *** reportedly occurred in 130 cases for GP,and actual patient injury or event occurred in 10 patients.A total of 149 patients(74%)reported with Injection GP events suffered no significant consequences due to the device failure,but 53 patients(26%)were affected by an *** GP and IGP are critical in managing gastrointestinal *** study of the FDA MAUDE database revealed the type,number,and trends of reported device-related adverse *** endoscopist and support staff must be aware of these device-related events and be equipped to manage them if they occur.

关键词： Hemostasis Gastrointestinal bleeding Endoscopy Device failure Bipolar coagulation Cautery Risks

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Impact of glucagon-like peptide receptor agonists on endoscopy and its preoperative management: Guidelines, challenges, and future directions

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World Journal of Gastrointestinal Endoscopy 2024年第6期16卷 292-296页

作者： Sahib Singh Vishnu Charan suresh kumar Ganesh Aswath Department of Internal Medicine Sinai HospitalBaltimoreMD 21215United States Division of Gastroenterology and Hepatology State University of New York Upstate Medical UniversitySyracuseNY 13210United States

Glucagon-like peptide receptor agonists(GLP-1RA)are used to treat type 2 diabetes mellitus and,more recently,have garnered attention for their effect-iveness in promoting weight *** have been associated with several gastrointestinal adverse effects,including nausea and *** side effects are presumed to be due to increased residual gastric *** the potential risk of aspiration and based on limited data,the American Society of Anesthesi-ologists updated the guidelines concerning the preoperative management of patients on GLP-1RA in *** included the duration of mandated cessation of GLP-1RA before sedation and usage of“full stomach”precautions if these medications were not appropriately held before the *** has led to additional challenges,such as extended waiting time,higher costs,and increased risk for *** this editorial,we review the current societal guidelines,clinical practice,and future directions regarding the usage of GLP-1RA in patients undergoing an endoscopic procedure.

关键词： Glucagon-like peptide receptor agonists Endoscopy Adverse events Intubation Aspiration Semaglutide Healthcare burden Guidelines

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Failure investigation on high velocity impact deformation of boron carbide(B_(4)C) reinforced fiber metal laminates of titanium/glass fiber reinforced polymer

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Defence Technology（防务技术） 2022年第6期18卷 963-975页

作者： S.suresh kumar P.A.Shankar K.Lalith kumar Department of Mechanical Engineering Sri Sivasubramaniya Nadar College of EngineeringKalavakkamChennai603110India

High velocity ballistic impact deformation behaviour of Titanium/GFRP Fiber Metal Laminates(FML)has been *** single and multiple projectiles impact conditions were ***/GFRP FML targets were fabricated with addition of 5%and 10%weight percentage of boron carbide(B_(4)C)*** properties of Ti/GFRP FML targets were determined as per ASTM *** velocity ballistic experiments were conducted using Armour Piercing Projectile(APP)of diameter 7.62 mm and velocity ranging between 350 and 450 m/*** of penetration of the projectile into the target was *** deformation behaviour of Ti/GFRP targets with and without the presence of ceramic powder(B_(4)C)was investigated.“Ductile hole growth”failure mode was observed for pure GFRP target when subjected to single projectile impact whereas“plugging”failure mode was noted for Ti/GFRP *** presence of B_(4)C(5%by weight)particles has significantly improved the ballistic resistance of the Ti/GFRP FML target by offering frictional resistance to the projectile *** addition(10%by weight)of B_(4)C has reduced the ballistic performance due to *** of the targets showed‘brittle cracking’or‘fragmentation’*** compared to the published results of Aluminium(Al 1100/GFRP and Al 6061/GFRP)FMLs,Ti/GFRP FML showed lesser DoP which increases its potential application to aerospace industry.

关键词： Ti/GFRP FML Ballistic impact Armour piercing projectile Boron carbide Depth of penetration Plugging

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Synthesis and Characterization of CdO–SnO_2 Nanocomposites Prepared by Hydrothermal Method

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Acta Metallurgica Sinica(English Letters) 2018年第3期31卷 254-262页

作者： Kapil Sirohi suresh kumar Virender Singh Anil Vohra Department of Electronic Science Kurukshetra University

In this work,（1-x）CdO-xSnO2 nanocomposites（≤0.15）have been synthesized via hydrothermal *** structural study reveals that CdO nanostructures possess crystalline phase and cubic *** CdO-SnO2 nanocomposites possess both cubic and orthorhombic structure with good *** crystallite size in the nanocomposites was found to be in the range of 9.6-19.6 *** emission scanning electronic microscopy and high-resolution tunnelling microscopy analysis confirm the presence of both cubic and orthorhombic structures which is also confirmed from X-ray diffraction *** transform infrared spectroscopy（FFIR）studies confirm that CdO-SnO2 nanocomposites possess the characteristics band of both CdO and SnO2 *** UV-visible absorption studies confirm that the optical absorption band in CdO-SnO2 nanocomposites possesses both blue and red shift as compared to that of CdO *** spectroscopy studies reveal the appearance of strong emission peak at 513,469 and 369 nm corresponding to green,blue and violet emission spectrum,respectively,in CdO-SnO2 *** FTIR studies confirm the presence of hydroxyl and water functional group due to atmospheric water vapours and chemical bonding in CdO and CdO-SnO2 *** spectroscopy confirms the presence of Raman bands of both CdO and SnO2 phases in the CdO-SnO2 nanocomposites.

关键词： Hydrothermal Nanocomposite CdO-SnO2 XRD FESEM HRTEM Optical properties

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Evaluation of thermostable endoglucanase in Paenibacillus lautus strain BHU3 for yield enhancement

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Systems Microbiology and Biomanufacturing 2022年第4期2卷 607-622页

作者： Suman Yadav Anand kumar Pandey suresh kumar Dubey Molecular Ecology Laboratory Centre of Advanced Study in BotanyInstitute of ScienceBanaras Hindu UniversityVaranasi 221005India Department of Biotechnology Engineering Institute of Engineering and TechnologyBundelkhand UniversityJhansi 284128India

In the present study,Paenibacillus lautus strain BHU3 isolated from landfill soil was evaluated for the presence of potential endoglucanases which are the first candidate of cellulase enzyme system to act on ***-silico analysis revealed high potential thermostable endoglucanases which can efficiently interact with *** most potent and thermostable endoglucanase(locus tag ***30_18280)belonged to glycosyl family-5 and had interaction energy of−12.981 kcal/mol for the best docked cluster containing three out of ten docking conformations,and Tm value of 73.3℃.MD simulation of 100 ns proved highly stable binding interactions of CPZ30_18280 endoglucanase with cellulose with root mean square deviation(RMSD)values ranging from 0.15 to 0.30 *** interactions with characteristic active site residues(tyrosine,tryptophan and aspartate)of glycosyl family-5 endoglucanases were ***,to enhance the production of endoglucanases,the fermentation conditions were optimized employing approaches like one factor at a time(OFAT)and response surface methodology(RSM).Maximum activity of endoglucanase was determined at 60℃.The optimized condi-tions for enhanced production of endoglucanase(10.15 U/mL)were pH 6.63,yeast extract conc.3.44 g/L,wheat bran 3.59%,and inoculum size 2.65%.Hence,*** strain BHU3 has enormous potential to synthesize highly efficient thermostable endoglucanases under optimized regime using ***,it could find immense industrial applications including large scale cellulose conversion to bioethanol.

关键词： Agrowastes Cellulose RAST Endoglucanase Paenibacillus lautus

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Efficient Hybrid Energy Optimization Method in Location Aware Unmanned WSN

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Intelligent Automation & Soft Computing 2023年第1期35卷 705-725页

作者： M.suresh kumar G.A.Sathish kumar Department of CSE Sri Venkateswara College of EngineeringSriperumbudur602117India Department of ECE Sri Venkateswara College of EngineeringSriperumbudur602117India

The growth of Wireless Sensor Networks(WSNs)has revolutionized thefield of technology and it is used in different application *** edges and other critical locations can be monitored using the navigation sensor *** WSN required low energy consumption to provide a high network and guarantee the ultimate *** main objective of this work is to propose hybrid energy optimization in local aware *** hybrid proposed work consists of clustering,optimization,direct and indirect communication and *** aim of this research work is to provide and framework for reduced energy and trusted communication with the shortest path to reach source to destination in WSN and an extending lifetime of wireless *** proposed Artificial Fish Swarm Optimization algorithm is used for energy optimization in military applications which is simulated using Network Simulator(NS)*** work optimizes the energy level and the same is compared with various genetic algorithms(GA)and also the cluster selection process was compared with thefission-fusion(FF)selection *** results of the proposed work show,improvement in energy optimization,throughput and time delay.

关键词： Wireless sensor networks(WSNs) optimization algorithm routing algorithm military applications

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Reflection of plane waves at the free surface of fiber-reinforced orthotropic thermoelastic rotating half-space with three-phase-lag model

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Journal of Ocean Engineering and Science 2021年第3期6卷 237-247页

作者： suresh kumar Sheokand Kapilkumar Kalkal Sunita Deswal Department of Mathematics Guru Jambheshwar University of Science and TechnologyHisar 125001HaryanaIndia

The present article is concerned with the propagation of plane waves in a homogeneous,fiber-reinforced orthotropic thermoelastic ro-tating half-space in the context of three-phase-lag *** exist three coupled waves,namely,quasi-longitudinal P-wave(qP),quasi-longitudinal thermal wave(qT)and quasi-transverse wave(qSV)in the *** reflection coefficients are computed numerically with the help of MATLAB programming and are depicted graphically to show the effects of rotation,fiber-reinforcement and phase lag *** expressions of energy ratios have also been obtained in explicit form and are shown graphically as functions of angle of *** has been verified that during reflection phenomena,the sum of energy ratios is equal to unity at each angle of *** of anisotropy is depicted on velocities of various reflected *** particular cases of interest have also been inferred from the present investigation.

关键词： Fiber-reinforcement Orthotropic Reflection Generalized thermoelasticity Three-phase-lag Rotation.

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Base pair distance analysis in single DNA molecule by direct stochastic optical reconstruction microscopy

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Chinese Chemical Letters 2015年第12期26卷 1490-1495页

作者： suresh kumar Chakkarapani Guenyoung Park Seong Ho Kang Department of Chemistry Graduate School Kyung Hee University Department of Applied Chemistry and Institute of Natural Sciences Kyung Hee University

Precise fluorescence imaging of single l-DNA molecules for base pair distance analysis requires a superresolution technique, as these distances are on the order of diffraction limit. Individual l-DNA molecules intercalated with the fluorescent dye YOYO-1 were investigated at subdiffraction spatial resolution by direct stochastic optical reconstruction microscopy（d STORM）. Various dye-to-DNA base pair ratios were imaged by photoswitching YOYO-1 between the fluorescent state and the dark state using two laser sources. The acquired images were reconstructed into a super-resolution image by applying Gaussian fitting to the centroid of the point spread function. By measuring the distances between localized fluorophores, the base pair distances in single DNA molecules for dye-to-DNA base pair ratios of 1：50,1：100, and 1：500 were calculated to be 17.1 0.8 nm, 34.3 2.2 nm, and 170.3 8.1 nm[17_TD$IF], respectively,which were in agreement with theoretical values. These results demonstrate that intercalating dye in a single DNA molecule can be photoswitched without the use of an activator fluorophore, and that super-localization precision at a spatial resolution of 17 nm was experimentally achieved.

关键词： stochastic DNA reconstructed fitting applying localization correction frames label localized

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