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儿童艰难梭菌感染诊治研究进展

国际儿科学杂志 2024年第7期51卷 444-447页

作者：田杰刘素琴扬州大学医学院附属扬州妇幼保健院儿科 225002

艰难梭菌(clostridium difficile,CD)是一种肠道条件致病菌,是抗生素相关性腹泻的主要病原体。近年来,儿童艰难梭菌感染(clostridium difficile infection,CDI)的发病率不断增加。最新数据显示,儿童CDI病例更多发生在医院以外,主要与社... 详细信息

艰难梭菌(clostridium difficile,CD)是一种肠道条件致病菌,是抗生素相关性腹泻的主要病原体。近年来,儿童艰难梭菌感染(clostridium difficile infection,CDI)的发病率不断增加。最新数据显示,儿童CDI病例更多发生在医院以外,主要与社区感染相关。依靠传统的检测技术很可能会造成儿童CDI的过度诊断及治疗,新的检测技术如挥发性有机化合物、促炎细胞因子和粪便代谢物的测定有望提高儿童CDI的诊断水平。儿童CDI一线治疗推荐甲硝唑和万古霉素,对于多次复发的儿童CDI,粪菌移植术有很好的治疗前景,但其长期安全性仍然未知,尚需进一步研究。该文对近年来儿童CDI的研究进展尤其是在流行病学、诊断和治疗等方面作一综述。

关键词：儿童艰难梭菌感染流行病学诊断治疗

Cu/g-C_(3)N_(4)修饰玻碳电极的制备及其电化学行为研究

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传感器与微系统 2024年第2期43卷 21-24页

作者：孙云飞司盼龙戴高鹏刘素芹湖北文理学院食品科学技术学院·化学工程学院湖北襄阳441053 湖北隆中实验室湖北襄阳441053

热解三聚氰胺制备石墨相氮化碳(g-C_(3)N_(4)),并进行XRD、SEM表征。将处理好的g-C_(3)N_(4)滴涂到裸电极表面,然后再电沉积铜,制得Cu/g-C_(3)N_(4)修饰玻碳电极(GCE)。实验发现该电极对多巴胺(DA)具有良好的电催化氧化作用。当DA的浓... 详细信息

热解三聚氰胺制备石墨相氮化碳(g-C_(3)N_(4)),并进行XRD、SEM表征。将处理好的g-C_(3)N_(4)滴涂到裸电极表面,然后再电沉积铜,制得Cu/g-C_(3)N_(4)修饰玻碳电极(GCE)。实验发现该电极对多巴胺(DA)具有良好的电催化氧化作用。当DA的浓度介于4.8×10^(-7)~1.0×10^(-5)mol/L时,与氧化峰电流呈良好的线性关系,其线性方程为Ipa(μA)=-7.416-0.272c(μmol/L),相关系数为0.9944;检测下限低至1.1×10^(-8)mol/L。考察了干扰物质对DA测定的影响,结果表明:该传感器选择性良好,同时也具有良好的稳定性和重现性。

关键词：石墨相氮化碳电沉积多巴胺化学修饰电极

宫腔镜曼月乐环固定术治疗子宫腺肌病临床效果分析

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中国医药科学 2024年第3期14卷 136-139,177页

作者：程启林刘素芹金玮杨益雯江苏省淮安市第五人民医院妇科江苏淮安223300

目的探讨宫腔镜曼月乐环固定术治疗子宫腺肌病的临床疗效。方法选取淮安市第五人民医院妇科2022年1—11月84例子宫腺肌病患者作为研究对象,用随机数表法分为对照组42例、观察组42例,对照组注射戈舍瑞林+宫内置曼月乐环;观察组行宫腔... 详细信息

目的探讨宫腔镜曼月乐环固定术治疗子宫腺肌病的临床疗效。方法选取淮安市第五人民医院妇科2022年1—11月84例子宫腺肌病患者作为研究对象,用随机数表法分为对照组42例、观察组42例,对照组注射戈舍瑞林+宫内置曼月乐环;观察组行宫腔镜下曼月乐环固定术,月经周期第1~5天给予促性腺激素释放激素类似物(GnRH-a)。比较两组生活质量综合评定问卷-74(GQOLI-74)、血红蛋白、雌二醇、痛经症状、不良反应、临床疗效。结果治疗后观察组患者的情感职能、社会功能、躯体功能、生理功能评分、血红蛋白高于对照组(P <0.05);观察组患者的雌二醇水平低于对照组(P <0.05)。观察组患者腹部下坠感、腰酸、背痛、恶心痛经症状总发生率低于对照组(P <0.05)。观察组患者阴道出血、头痛、脱环不良反应总发生率低于对照组(P <0.05)。观察组患者临床总有效率高于对照组(P <0.05)。结论采用宫腔镜曼月乐环固定术治疗,可改善子宫腺肌病患者血红蛋白、雌二醇水平,提高患者生活质量,降低痛经症状、不良反应,临床使用效果较好。

关键词：宫腔镜曼月乐环固定术子宫腺肌病血红蛋白雌二醇不良反应

Highlights and new Editorial Advisory Board members of the Journal of Environmental Sciences

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Journal of Environmental Sciences 2016年第9期28卷 1-6页

作者： Qingcai Feng suqin liu Zhengang Mao Jian Xu Zixuan Wang X.Chris Le Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Division of Analytical and Environmental Toxicology Department of Laboratory Medicine and PathologyUniversity of Alberta

The Journal of Environmental Sciences（JES）is honored to welcome Professors/Drs William ***,Jiuhui Qu,Susan ***,Jerald ***,Hongxiao Tang,Shu Tao,and Hugh *** to serve on the Editorial Advisory Board（EAB）.Their tremendous experience in scientific publications,leading expertise in topic areas pertinent to JES,diverse international networks/perspectives,and exemplary dedication to scientific excellence will guide and help the continuing healthy growth of JES.

关键词： honored welcome publications expertise Richardson continuing diverse excellence tremendous disinfection

网织红细胞、血清铁蛋白、VitB_(12)联合检测在MDS与MA鉴别诊断中的应用价值

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中国医学创新 2024年第27期21卷 148-152页

作者：徐小津丁益群刘苏琴杨子东吉安市中心人民医院核医学科江西吉安343000 吉安市中心人民医院输血科江西吉安343000 吉安市中心人民医院检验科江西吉安343000

目的:探讨网织红细胞、血清铁蛋白(SF)、维生素B_(12)(VitB_(12))联合检测在骨髓增生异常综合征(MDS)与巨幼细胞贫血(MA)鉴别诊断中的应用价值。方法:选取2020年7月—2023年11月吉安市中心人民医院收治的MDS患者43例纳入MDS组,MA患者43... 详细信息

目的:探讨网织红细胞、血清铁蛋白(SF)、维生素B_(12)(VitB_(12))联合检测在骨髓增生异常综合征(MDS)与巨幼细胞贫血(MA)鉴别诊断中的应用价值。方法:选取2020年7月—2023年11月吉安市中心人民医院收治的MDS患者43例纳入MDS组,MA患者43例纳入MA组,另选取于本院体检的健康体检者43例纳入对照组,比较三组血浆网织红细胞、SF及血清VitB_(12)水平,通过受试者操作特征(ROC)曲线分析三项指标单独或联合检测对MDS的诊断效能。结果:MDS组、MA组网织红细胞血红蛋白(Ret-He)、未成熟网织红细胞指数(IRF)、中荧光强度网织红细胞比率(MFR)、高荧光强度网织红细胞比率(HFR)水平均高于对照组,差异均有统计学意义(P0.05);MDS组Ret-He水平低于MA组,差异有统计学意义(P<0.05);MDS组、MA组SF水平均高于对照组,差异均有统计学意义(P<0.05);MDS组血清VitB_(12)水平高于对照组,MA组血清VitB_(12)水平低于对照组,差异均有统计学意义(P<0.05);MDS组SF、VitB_(12)水平均高于MA组,差异均有统计学意义(P<0.05)。网织红细胞参数Ret-He与SF、VitB_(12)联合检测诊断MDS时ROC曲线下面积为0.942,高于三项指标单独检测曲线下面积0.755、0.813、0.830,差异均有统计学意义(P<0.05)。结论:网织红细胞联合SF和VitB_(12)对于指导MDS诊断具有一定的价值,MDS的SF、VitB_(12)均高于MA,Ret-He低于MA,可作为临床疾病鉴别的重要参考指标。

关键词：骨髓增生异常综合征再生障碍性贫血网织红细胞血清铁蛋白维生素B_(12)

Cover features and new Associate Editors of the Journal of Environmental Sciences

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Journal of Environmental Sciences 2016年第10期28卷 1-5页

We are very pIeased to announce that five Associate Editors have joined the editorial team of the Joumal of Environmental Sciences （JES）. Professors/Drs. Yong Cai, Paul Lain, Jonathan Martin, Michael Plewa, and Po Keung Wong bring a wealth of expertise in environmental sciences. As preeminent scientists in their chosen areas of research.

关键词： Cover features and new Associate Editors of the Journal of Environmental Sciences DBPs

Electrochemical characteristics of amorphous MgTi_xNi(x = 0,0.1,and 0.2) hydrogen storage alloys

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Rare Metals 2010年第5期29卷 486-490页

作者： liu suqin,ZHAO Wenjuan,HUANG Kelong,and HUANG Hongxia College of Chemistry and Chemical Engineering,Central South University,Changsha 410083,China College of Chemistry and Chemical Engineering Central South University Changsha China

MgTixNi （x = 0, 0.1, and 0.2） alloys were successfully prepared by mechanical alloying （MA）, and the influence of milling time on the electrochemical characteristics of the electrodes was discussed. MgTixNi alloys after 90 h milling displayed the best electrochemical performance The X-ray diffraction patterns showed that the alloy ball-milled for 90 h was amorphous with a widened diffraction peak. The charge-discharge tests indicated that these alloys had good electrochemical activation properties, and the MgTi0.2Ni alloy electrode exhibited the best cycle performance. The initial discharge capacity of the MgTi0.2Ni alloy reached up to 401.1 mAh·g^-1, and the retention rate of capacity was 31.0% after 30 cycles, much higher than that of MgNi （17.3%）. The Tafel polarization curves revealed that Ti addition could enhance the anticorrosion performance of these alloys in alkali solution, which was responsible for the ameliorated cyclic stability of these alloy electrodes.

关键词： hydrogen storage alloys titanium electrochemical properties mechanical alloying

One-step synthesis of graphitic carbon nitride nanosheets for efficient catalysis of phenol removal under visible light

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Chinese Journal of Catalysis 2017年第10期38卷 1711-1718页

作者： Wang Ding suqin liu Zhen He College of Chemistry and Chemical Engineering Central South University Changsha 410083 Hunan China

Graphitic carbon nitride(g‐C3N4)nanosheet photocatalysts were synthesized via a facile impregnation‐thermal *** as‐prepared materials were characterized and investigated as metal‐free photocatalysts for the degradation of phenol in aqueous solution under visible *** revealed that the g‐C3N4nanosheets exhibited a78.9%degradation for phenol after30min,which was much faster than that of the pristine g‐*** Brunauer‐Emmett‐Teller theory,the surface area of g‐C3N4nanosheets was103.24m2/g,which was much larger than that of g‐*** larger surface area increases the contact area of the material with phenol,enhancing the photocatalytic *** results highlight the potential application of sustainable metal‐free photocatalysts in water purification.

关键词： g‐C3N4 nanosheet Phenol degradation Polymer Semiconductor Photocatalyst

Influences of Ti substitution on the structure and electrochemical properties of Mg_(1-x)Ti_xNi(x=0,0.1, 0.2, and 0.3) hydrogen storage alloys

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Rare Metals 2009年第5期28卷 504-510页

作者： HUANG Hongxia HUANG Kelong liu suqin CHEN Dongyang College of Chemistry and Chemical Engineering Central South University Changsha 410083 China Department of Materials and Chemical Engineering Guilin University of Technology Guilin 541004 China

MgNi-based hydrogen storage alloys Mg1–xTixNi （x = 0, 0.1, 0.2, and 0.3） were prepared by means of mechanical alloying. Mg in the alloy was partially substituted by Ti to improve the cycle stability of the alloys. The effects of the substitution of Ti for Mg on the microstructure and electrochemical performances of the alloys were investigated in detail. The results indicate that the substitution of Ti for Mg obviously decreases the discharge capacity, but it significantly improves their cycle stabilities. The microstructure of the alloys analyzed by X-ray diffraction （XRD） and scanning electron microscopy （SEM） shows that the alloys have a dominatingly amorphous structure. The substitution of Ti for Mg helps to improve the anti-oxidation/corrosion ability of the MgNi alloy but demolishes the electrochemical kinetics of hydrogenation/dehydrogenation. The Mg0.9Ti0.1Ni alloy electrode milled for 80 h exhibits the best integrative capability, which has the maximal discharge capacity of 331.66 mAh/g and the C30/Cmax of 63.65%.

关键词： hydrogen storage alloys Ti substitution structural characteristic electrochemical properties