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Chinese Journal of Aeronautics 2019年第9期32卷 2164-2173页

作者： sunyoung kim Changho KANG Changook PARK Department of Mechanical and Aerospace Engineering Seoul National UniversitySeoul 08826Republic of Korea BK21+Transformative Training Program for Creative Mechanical and Aerospace Engineers Seoul National UniversitySeoul 08826Republic of Korea Automation and Systems Research Institute Seoul 08826Republic of Korea Institute of Advanced Aerospace Technology Seoul 08826Republic of Korea

In this paper, a cardinality compensation method based on Information-weighted Consensus Filter(ICF) using data clustering is proposed in order to accurately estimate the cardinality of the Cardinalized Probability Hypothesis Density(CPHD) filter. Although the joint propagation of the intensity and the cardinality distribution in the CPHD filter process allows for more reliable estimation of the cardinality(target number) than the PHD filter, tracking loss may occur when noise and clutter are high in the measurements in a practical situation. For that reason, the cardinality compensation process is included in the CPHD filter, which is based on information fusion step using estimated cardinality obtained from the CPHD filter and measured cardinality obtained through data clustering. Here, the ICF is used for information fusion. To verify the performance of the proposed method, simulations were carried out and it was confirmed that the tracking performance of the multi-target was improved because the cardinality was estimated more accurately as compared to the existing techniques.

关键词： Cardinality compensation Cardinalized probability hypothesis density filter Data clustering Information-weighted consensus filter Multi-target tracking

Global public concern of childhood and adolescence suicide:a new perspective and new strategies for suicide prevention in the post-pandemic era

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World Journal of Pediatrics 2024年第9期20卷 872-900页

作者： Soeun kim Jaeyu Park Hyeri Lee Hayeon Lee Selin Woo Rosie Kwon sunyoung kim Ai Koyanagi Lee Smith Masoud Rahmati Guillaume Fond Laurent Boyer Jiseung Kang Jun Hyuk Lee Jiyeon Oh Dong Keon Yon Center for Digital Health Medical Science Research InstituteKyung Hee University College of MedicineSeoulSouth Korea Department of Precision Medicine Kyung Hee University College of MedicineSeoulSouth Korea Department of Regulatory Science Kyung Hee UniversitySeoulSouth Korea Department of Family Medicine Kyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Research and Development Unit Parc Sanitari Sant Joan de DeuBarcelonaSpain Centre for Health Performance and WellbeingAnglia Ruskin UniversityCambridgeUK Department of Physical Education and Sport Sciences Faculty of Literature and Human SciencesLorestan UniversityKhoramabadIran Department of Physical Education and Sport Sciences Faculty of Literature and HumanitiesVali-e-Asr University of RafsanjanRafsanjanIran CEReSS-Health Service Research and Quality of Life Center Assistance Publique-Hôpitaux de MarseilleAix Marseille UniversityMarseilleFrance Department of Anesthesia Critical Care and Pain MedicineMassachusetts General HospitalBostonMAUSA Division of Sleep Medicine Harvard Medical SchoolBostonMAUSA Health and Human Science University of Southern CaliforniaLos AngelesCAUSA Department of Medicine Kyung Hee University College of MedicineSeoulSouth Korea Department of Pediatrics Kyung Hee University Medical CenterKyung Hee University College of Medicine23 Kyungheedae-roDongdaemun-guSeoul02447South Korea

Background Suicide is the second leading cause of death in young people worldwide and is responsible for about 52,000 deaths annually in children and adolescents aged 5-19 ***,social,psychological,and behavioral factors play important roles in suicide *** traumatic events such as the COVID-19 pandemic may contribute to suicidal behaviors in young people,there is a need to understand the current status of suicide in adolescents,including its epidemiology,associated factors,the influence of the pandemic,and management *** sources We investigated global and regional suicide mortality rates among children and adolescents aged 5-19 years using data from the Global Burden of Diseases,Injuries,and Risk Factors Study(GBD)*** suicide mortality rates from 1990 to 2019 were examined in 204 countries and territories across six World Health Organization(WHO)***,we utilized electronic databases,including PubMed/MEDLINE and Scopus,and employed various combinations of terms such as“suicide”,“adolescents”,“youth”,“children”,“risk factors”,“COVID-19 pandemic”,“prevention”,and“intervention”to provide a narrative review on suicide within the pediatric population in the post-pandemic *** Despite the decreasing trend in the global suicide mortality rate from 1990 to 2019,it remains *** mortality rates from suicide by firearms or any other specified means were both greater in ***,Southeast Asia had the highest suicide rate among the six WHO *** COVID-19 pandemic seems to contribute to suicide risk in young people;thus,there is still a strong need to revisit appropriate management for suicidal children and adolescents during the *** The current narrative review integrates up-to-date knowledge on suicide epidemiology and the effects of the COVID-19 pandemic,risk factors,and intervention *** numerous studies have characterized trends in suicide among young people during the

关键词： COVID-19 Global Pandemic Suicide Children Adolescents

National trends in sexual intercourse and usage of contraception among Korean adolescents

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World Journal of Pediatrics 2024年第9期20卷 935-948页

作者： Jun Hyuk Lee Myeongcheol Lee Hojae Lee Jaeyu Park sunyoung kim Ai Koyanagi Lee Smith Min Seo kim Guillermo F.López Sánchez Elena Dragioti Masoud Rahmati Jiseung Kang Hans Oh Dong Keon Yon Center for Digital Health Medical Science Research InstituteKyung Hee University College of MedicineSeoulSouth Korea Health and Human Science University of Southern CaliforniaLos AngelesCAUSA Department of Regulatory Science Kyung Hee UniversitySeoulSouth Korea Department of Family Medicine Kyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Research and Development Unit Parc Sanitari Sant Joan de DeuBarcelonaSpain Centre for Health Performance and WellbeingAnglia Ruskin UniversityCambridgeUK Cardiovascular Disease Initiative Broad Institute of MIT and HarvardCambridgeMAUSA Division of Preventive Medicine and Public Health Department of Public Health SciencesSchool of MedicineUniversity of MurciaMurciaSpain Pain and Rehabilitation Centre Department of Medical and Health SciencesLinköping UniversityLinköpingSweden Research Laboratory Psychology of Patients Department of NursingSchool of Health SciencesFamiliesand Health ProfessionalsUniversity of IoanninaIoanninaGreece Department of Physical Education and Sport Sciences Faculty of Literature and Human SciencesLorestan UniversityKhoramabadIran Department of Physical Education and Sport Sciences Faculty of Literature and HumanitiesVali-E-Asr University of RafsanjanRafsanjanIran Department of Anesthesia Critical Care and Pain MedicineMassachusetts GeneralHospitalBostonMAUSA Division of Sleep Medicine Harvard Medical SchoolBostonMAUSA Suzanne Dworak Peck School of Social Work University of Southern CaliforniaLos AngelesCAUSA Department of Pediatrics Kyung Hee University College of Medicine23 Kyungheedae-RoDongdaemun-guSeoul02447South Korea Present Address:CEReSS-Health Service Research and Quality of Life Center Aix-Marseille UniversityMarseilleFrance

Background The exact influence of the COVID-19 pandemic on sexual intercourse and usage of contraception remains largely uncharted *** bridge this gap in knowledge,we conducted a comprehensive,cross-sectional examination of long-term trends in the prevalence of sexual intercourse and usage of contraception among South Korean adolescents from 2006 to *** In our research,we drew upon data encompassing 1,138,799 South Korean adolescents aged 12 to 18 years,derived from the Korean Youth Risk Behavior Web-based Survey(KYRBS)over a period spanning from 2006 to *** focused on the prevalence of sexual intercourse,contraception utilization,and the underlying associated factors among this *** KYRBS data was collected using a complex sampling strategy to determine the national prevalence estimates and shifts in prevalence before(2006-2019)and during(2020-2022)the COVID-19 pandemic *** During the pre-pandemic period,a decrease in adolescent sexual intercourse was observed(6.34%in 2006,5.53%in 2012,and 5.87%in 2019).However,in the post-pandemic period(2020-2022),there was a surge in sexual intercourse(4.55%in 2020 and 6.20%in 2022).This evident alteration in sexual intercourse trajectory between pre-and post-pandemic periods was statistically significant[βdiff,0.950;95%confidence interval(CI),0.756-1.144].Regarding contraceptive use among South Korean adolescents,there was an increase in the pre-COVID-19 pandemic phase across all demographic segments(14.61%in 2006,22.30%in 2012,and 47.69%in 2022)but a notable decline when compared with the pre-and post-pandemic periods(βdiff,-0.319;95%CI,-0.454 to-0.184).Additionally,during the study period,a decrease in sexual intercourse was observed in the pre-pandemic period(β,-0.129;95%CI,-0.148 to-0.110),followed by an increase in the post-pandemic period(β,0.821;95%CI,0.627 to 1.014).This shift is highlighted by an effect size of 0.96[weighted odds ratio(wOR);95%CI,0.92 to 1.00],indicating a subst

关键词： Adolescent Contraception COVID-19 Pandemic Risky sexual behavior

Differences in Pandemic-Related Factors Associated with Alcohol and Substance Use among Korean Adolescents:Nationwide Representative Study

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Biomedical and Environmental Sciences 2023年第6期36卷 542-548页

作者： Hyunju Yon Sangil Park Jung U Shin Ai Koyanagi Louis Jacob Lee Smith Chanyang Min Jinseok Lee Rosie Kwon Guillaume Fond Laurent Boyer sunyoung kim Namwoo kim Sang Youl Rhee Jae Il Shin Dong Keon Yon Ho Geol Woo Department of Medicine Kyung Hee University College of MedicineSeoulRepublic of Korea Department of Neurology Kyung Hee University Medical CenterSeoulRepublic of Korea Department of Dermatology CHA Bundang Medical CenterCHA University School of MedicineSeongnamRepublic of Korea Research and Development Unit Parc Sanitari Sant Joan de DeuCIBERSAMISCIIIBarcelonaSpain Catalan Institution for Research and Advanced Studies(ICREA) Pg.Lluis CompanysBarcelonaSpain Department of Physical Medicine and Rehabilitation Lariboisière-Fernand Widal HospitalAP-HPUniversity Paris CitéParisFrance Centre for Health Performance and WellbeingAnglia Ruskin UniversityCambridgeUK Center for Digital Health Medical Science Research InstituteKyung Hee University Medical CenterKyung Hee University College of MedicineSeoulRepublic of Korea Department of Biomedical Engineering Kyung Hee UniversityYonginRepublic of Korea Assistance Publique-Hôpitaux de Marseille(AP-HM) Aix-Marseille UniversityCEReSSHealth Service Research and Quality of Life CenterMarseilleFrance FondaMental Foundation CreteilFrance Department of Family Medicine Kyung Hee University College of MedicineSeoulRepublic of Korea Department of Psychiatry Seoul St.Mary's HospitalThe Catholic University of KoreaCollege of MedicineSeoulRepublic of Korea Department of Endocrinology and Metabolism Kyung Hee University School of MedicineSeoulRepublic of Korea Department of Pediatrics Yonsei University College of MedicineSeoulRepublic of Korea Department of Pediatrics Kyung Hee University College of MedicineSeoulRepublic of Korea

The coronavirus disease 2019(COVID-19)pandemic has raised concerns about the mental health and social well-being of youth,including its potential to increase or exacerbate substance use behaviors[1].Among adolescents,the COVID-19pandemic has resulted in limited face-to-face school contact and thus missed milestones in preventing alcohol and substance use.

关键词： Alcohol raised alcohol

Estimated prevalence and trends in smoking among adolescents in South Korea,2005-2021:a nationwide serial study

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World Journal of Pediatrics 2023年第4期19卷 366-377页

作者： Hyoin Shin Sangil Park Hyunju Yon Chae Yeon Ban Stephen Turner Seong Ho Cho Youn Ho Shin Jung U.Shin Ai Koyanagi Louis Jacob Lee Smith Chanyang Min Young Joo Lee So Young kim Jinseok Lee Rosie Kwon Min Ji Koo Guillaume Fond Laurent Boyer Jong Woo Hahn Namwoo kim Sang Youl Rhee Jae Il Shin Ho Geol Woo Hyeowon Park Hyeon Jin kim Yoonsung Lee Man S.kim Eléa Lefkir Vlasta Hadalin Jungwoo Choi Seung Won Lee Dong Keon Yon sunyoung kim Department of Medicine Kyung Hee University College of MedicineSeoulSouth Korea Department of Neurology Kyung Hee University College of MedicineSeoulSouth Korea Maternity and Child Health Division NHS Grampian AberdeenAberdeenUK Division of Allergy-Immunology University of South Florida Morsani College of MedicineTampaFLUSA Department of Pediatrics CHA Gangnam Medical CenterCHA University School of MedicineSeoulSouth Korea Department of Dermatology CHA Bundang Medical CenterCHA University School of MedicineSeongnamSouth Korea Research and Development Unit Parc Sanitari Sant Joan de DeuCIBERSAMISCIIIBarcelonaSpain Catalan Institution for Research and Advanced Studies(ICREA) Pg.Lluis CompanysBarcelonaSpain Faculty of Medicine University of Versailles Saint-Quentin-en-YvelinesMontigny-Le-BretonneuxFrance Centre for Health Performance and WellbeingAnglia Ruskin UniversityCambridgeUK Center for Digital Health Medical Science Research InstituteKyung Hee University Medical CenterKyung Hee University College of Medicine23 Kyungheedae-RoDongdaemun-GuSeoul02447South Korea Department of Obstetrics and Gynecology Kyung Hee University College of MedicineSeoulSouth Korea Department of Otorhinolaryngology-Head and Neck Surgery CHA Bundang Medical CenterCHA University School of MedicineSeongnamSouth Korea Department of Biomedical Engineering Kyung Hee UniversityYonginSouth Korea Department of Biomedical Engineering University of MichiganAnn ArborMIUSA Department of Human Biology University of TorontoTorontoONCanada AP-HM Aix-Marseille Univ.CEReSS—Health Service Research and Quality of Life CenterMarseilleFrance FondaMental Foundation CreteilFrance Department of Pediatrics Seoul National University College of MedicineSeoulSouth Korea Department of Neuropsychiatry Seoul National University College of MedicineSeoulSouth Korea Department of Endocrinology and Metabolism Kyung Hee University School of MedicineSeoulSouth Korea Department of Pediatrics Yonsei University College of

Background Although smoking is classified as a risk factor for severe COVID-19 outcomes,there is a scarcity of studies on prevalence of smoking during the COVID-19 ***,this study aims to analyze the trends of prevalence of smoking in adolescents over the COVID-19 pandemic *** The present study used data from middle to high school adolescents between 2005 and 2021 who participated in the Korea Youth Risk Behavior Web-based Survey(KYRBS).We evaluated the smoking prevalence(ever or daily)by year groups and estimated the slope in smoking prevalence before and during the *** A total of 1,137,823 adolescents participated in the study[mean age,15.04 years[95%confidence interval(CI)15.03-15.06];and male,52.4%(95%CI 51.7-53.1)].The prevalence of ever smokers was 27.7%(95%CI 27.3-28.1)between 2005 and 2008 but decreased to 9.8%(95%CI 9.3-10.3)in 2021.A consistent trend was found in daily smokers,as the estimates decreased from 5.4%(95%CI 5.2-5.6)between 2005 and 2008 to 2.3%(95%CI 2.1-2.5)in ***,the downward slope in the overall prevalence of ever smokers and daily smokers became less pronounced in the COVID-19 pandemic period than in the pre-pandemic *** the subgroup with substance use,the decreasing slope in daily smokers was significantly more pronounced during the pandemic than during the pre-pandemic *** The proportion of ever smokers and daily smokers showed a less pronounced decreasing trend during the *** findings of our study provide an overall understanding of the pandemic's impact on smoking prevalence in adolescents.

关键词： Adolescent COVID-19 Daily smokers Ever smokers Pandemic Smoking

National trends in alcohol and substance use among adolescents from 2005 to 2021:a Korean serial cross‑sectional study of one million adolescents

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World Journal of Pediatrics 2023年第11期19卷 1071-1081页

作者： Sangil Park Hyunju Yon Chae Yeon Ban Hyoin Shin Seounghyun Eum Seung Won Lee Youn Ho Shin Jung UShin Ai Koyanagi Louis Jacob Lee Smith Chanyang Min AbdullahÖzgür Yeniova So Young kim Jinseok Lee Vlasta Hadalin Rosie Kwon Min Ji Koo Guillaume Fond Laurent Boyer sunyoung kim Jong Woo Hahn Namwoo kim Eléa Lefkir Victoire Bondeville Sang Youl Rhee Jae Il Shin Dong Keon Yon Ho Geol Woo Department of Neurology Kyung Hee University Medical Center23 Kyungheedae‑roDongdaemun‑guSeoul 02447South Korea Department of Medicine Kyung Hee University College of MedicineSeoulSouth Korea Department of Precision Medicine Sungkyunkwan University School of MedicineSuwonSouth Korea Department of Pediatrics CHA Gangnam Medical CenterCHA University School of MedicineSeoulSouth Korea Department of Dermatology CHA Bundang Medical CenterCHA University School of MedicineSeongnamSouth Korea Research and Development Unit Parc Sanitari Sant Joan de DeuCIBERSAMISCIIIBarcelonaSpain Catalan Institution for Research and Advanced Studies(ICREA) Pg.Lluis CompanysBarcelonaSpain Faculty of Medicine University of Versailles Saint-Quentin-en-YvelinesMontigny‑le‑BretonneuxFrance Centre for Health Performance and WellbeingAnglia Ruskin UniversityCambridgeUK Center for Digital Health Medical Science Research InstituteKyung Hee University Medical CenterKyung Hee University College of MedicineSeoulSouth Korea Division of Gastroenterology Department of Internal MedicineFaculty of MedicineTokat Gaziosmanpaşa UniversityTokatTurkey Department of Otorhinolaryngology‑Head&Neck Surgery CHA Bundang Medical CenterCHA University School of MedicineSeongnamSouth Korea Department of Biomedical Engineering Kyung Hee UniversityYonginSouth Korea Faculty of Medicine University of LjubljanaLjubljanaSlovenia Department of Biomedical Engineering University of MichiganAnn ArborMIUSA Department of Human Biology University of TorontoTorontoONCanada AP-HM Aix-Marseille UniversityCEReSS-Health Service Research and Quality of Life CenterMarseilleFrance FondaMental Foundation CreteilFrance Department of Family Medicine Kyung Hee University College of MedicineSeoulSouth Korea Department of Pediatrics Seoul National University Bundang HospitalSeongnamSouth Korea Department of Neuropsychiatry Seoul National University HospitalSeoulSouth Korea Faculty of Medicine University of Rennes 1RennesFrance Department

Background Although previous studies have provided data on early pandemic periods of alcohol and substance use in adolescents,more adequate studies are needed to predict the trends of alcohol and substance use during recent periods,including the mid-pandemic *** study investigated the changes in alcohol and substance use,except tobacco use,throughout the pre-,early-,and mid-pandemic periods in adolescents using a nationwide serial cross-sectional survey from South *** Data on 1,109,776 Korean adolescents aged 13–18 years from 2005 to 2021 were obtained in a survey operated by the Korea Disease Control and Prevention *** evaluated adolescents’alcohol and substance consumption prevalence and compared the slope of alcohol and substance prevalence before and during the COVID-19 pandemic to see the trend *** define the pre-COVID-19 period as consisting of four groups of consecutive years(2005–2008,2009–2012,2013–2015,and 2016–2019).The COVID-19 pandemic period is composed of 2020(early-pandemic era)and 2021(midpandemic era).Results More than a million adolescents successfully met the inclusion *** weighted prevalence of current alcohol use was 26.8%[95%confidence interval(CI)26.4–27.1]from 2005 to 2008 and 10.5%(95%CI 10.1–11.0)in 2020 and *** weighted prevalence of substance use was 1.1%(95%CI 1.1–1.2)from 2005 to 2008 and 0.7%(95%CI 0.6–0.7)between 2020 and *** 2005 to 2021,the overall trend of use of both alcohol and drugs was found to decrease,but the decline has slowed since COVID-19 epidemic(current alcohol use:βdiff 0.167;95%CI 0.150–0.184;substance use:βdiff 0.152;95%CI 0.110–0.194).The changes in the slope of current alcohol and substance use showed a consistent slowdown with regard to sex,grade,residence area,and smoking status from 2005 to *** The overall prevalence of alcohol consumption and substance use among over one million Korean adolescents from the early and mid-stage(2020–2021)of the COVID

关键词： Alcohol Adolescent Corona virus disease 2019 South Korea Substance use

PARTIAL RECONSTITUTION OF BOTANICAL EXTRACT PG102 BY COMBINING CHEMICAL COMPOUNDS KNOWN TO BE PRESENT IN ACTINIDIA ARGUTA: IMPLICATIONS FOR QC OF PHYTOMEDICINES

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World Journal of Traditional Chinese Medicine 2015年第4期1卷 91-91页

作者： Doo Suk Lee sunyoung kim the PG102 group Viromed Co. Ltd. School of Biological Sciences Seoul National University

One of the most important factors limiting the success of plant-derived therapeutics is that these products are generally a mixture containing many different *** compounds responsible for bioactivities and/or clinical... 详细信息

关键词： PG IMPLICATIONS FOR QC OF PHYTOMEDICINES PARTIAL RECONSTITUTION OF BOTANICAL EXTRACT PG102 BY COMBINING CHEMICAL COMPOUNDS KNOWN TO BE PRESENT IN ACTINIDIA ARGUTA

USE OF CELL-BASED BIOASSAY FOR THE QUALITY CONTROL OF BOTANICAL THERAPEUTICS

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World Journal of Traditional Chinese Medicine 2015年第4期1卷 91-91页

作者： Doo Suk Lee Min-Jung Bae sunyoung kim botanical therapeutics group Viromed Co. Ltd. School of Biological Sciences Seoul National University

The single most important factor in modernization efforts of traditional oriental medicines is the limited understanding of active compounds responsible for claimed therapeutic ***,the unknown identity of biologically active molecules generates major difficulties associated with botanical therapeutics in *** includes management of raw materials,poor understanding of

关键词： USE OF CELL-BASED BIOASSAY FOR THE QUALITY CONTROL OF BOTANICAL THERAPEUTICS PG

Role of glutathione transferase in phase separation of FUS and TAF15 in neurons

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Neural Regeneration Research 2025年第7期20卷 1999-2000页

作者： Kiyoung kim Department of Medical Science Soonchunhyang UniversityAsanKorea

Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord,leading to muscle weakness,paralysis,and ultimately death(Cleveland and Rothstein,2001).Frontotemporal lobar degeneration(FTLD)is a neurodegenerative disease affecting the frontal and temporal lobes of the brain,leading to changes in behavior,personality,and language(Van Langenhove et al.,2012).Both ALS and FTLD are classified as proteinopathies in which abnormal protein aggregation and accumulation in neurons contribute to the disease *** in sarcoma(FUS)is a DNA/RNA-binding protein involved in various cellular processes,including transcriptional regulation,RNA splicing,and DNA *** in the FUS gene have been linked to familial ALS,highlighting the importance of FUS in the disease pathogenesis(Vance et al.,2009).In ALS and FTLD,aberrant post-translational modifications(PTMs)of FUS,such as phosphorylation,acetylation,and methylation,have been implicated in the promotion of FUS aggregation and neurotoxicity(Choi et al.,2023).Therefore,understanding the regulatory mechanisms of FUS PTMs is crucial for developing targeted therapies against these diseases.

关键词： degeneration FUS aggregation

Molecules “buckle up” to drive layered hybrid perovskites into single-crystal nanowires in water

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Science China Chemistry 2025年第01期 3-4页

作者： Seokhyoung kim Department of Chemistry Michigan State University

Layered 2D metal halide perovskites (MHPs) are one of the most exciting candidates for next-generation light sources owing to their outstanding optoelectronic properties. These properties are readily tunable by controlling the halide composition, number of inorganic layers, and the chemistry of organic cations. Another key element that can substantially impact the materials’ functionalities is crystal morphology [1].

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