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Carcinoma bladder and sliding bladder hernia: Unusual association of paramount significance

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Asian Journal of Urology 2020年第2期7卷 186-187页

作者： Manav Agrawal Gaurav Garg sunny goel Manoj Kumar Department of Urology King George’s Medical UniversityLucknowUttar PradeshIndia

A 60-year-old man,a diagnosed case of inguinal hernia was referred for evaluation of voiding lower urinary tract symptoms(LUTS).There was no history of *** local examination,he had right-sided-direct inguinal hernia with right *** biochemical parameters were within normal *** routine microscopy revealed presence of field full of red blood *** uroflowmetry there was presence of decreased peak flow rate(12 mL/s)and average flow rate(8 mL/s).

关键词： bladder hernia Carcinoma

Role of gemcitabine and cisplatin as neoadjuvant chemotherapy in muscle invasive bladder cancer: Experience over the last decade

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Asian Journal of Urology 2019年第3期6卷 222-229页

作者： sunny goel Rahul J.Sinha Ved Bhaskar Ruchir Aeron Ashish Sharma Vishwajeet Singh Department of Urology King George Medical UniversityLucknowIndia

Objective:Neoadjuvant chemotherapy followed by radical cystectomy is considered the standard of care for patients with muscle invasive bladder *** the last decade,interest in neoadjuvant chemotherapy has slowly shifted from methotrexate,vinblastine,doxorubicin and cisplatin regime to gemcitabine and cisplatin *** are many publications on gemcitabine and cisplatin regime in literature which cover different aspects of *** review aims to summarise the findings published so far on gemcitabine and cisplatin regime and present it in a concise ***:A systematic literature review was conducted searching the PubMeddatabase in December 2016 using the medical subject heading(MeSH)with the terms gemcitabine,cisplatin,chemotherapy,muscle invasive bladder cancer,and *** relevant studies were included and results were ***:A total of 13 studies were included which published between 2007 and *** 13 studies comprised of 754 subjects suffering from muscle invasive bladder *** proportion of male patients ranged from 60%to 86.4%and the median age ranged from 54.2 to 77.3 years in various *** pathological response(pT0)was seen in 30.0%of patients and pathological downstaging(

关键词： Muscle invasive bladder cancer Gemcitabine Cisplatin Neoadjuvant chemotherapy Radical cystectomy

Solar rooftop in India: Policies,challenges and outlook

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Green Energy & Environment 2016年第2期1卷 129-137页

作者： Malti goel Science & Technological Solutions for Sustainable Energy Future Climate Change Research Institute

Solar photovoltaic rooftop has emerged as a potential green technology to address climate change issues by reducing reliance on conventional fossil fuel based energy. With a strong commitment to increase the renewable sources based energy capacity to 175 GW by 2022, India has a target to install 100 GW of solar energy capacity. Of this 40 GW would be the share of grid connected solar PV rooftop. This paper examines global growth in solar energy, world's major rooftop installed capacity countries' policies and solar rooftop policy instruments in India. The current Indian goals, issues & challenges in achieving them and trends in further development are discussed.

关键词： Solar energy India Rooftop PV Policies Outlook

Experimental investigation on mechanical properties of binary and ternary blended pervious concrete

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Frontiers of Structural and Civil Engineering 2020年第1期14卷 229-240页

作者： Rekha SINGH Sanjay goel Department of Civil Engineering I.K.Gujral Punjab Technical UniversityJalandhar 144603India Department of Civil Engineering DAV Institute of Engineering and TechnologyJalandhar 144008India

The purpose of the investigation was to study the effect of binary and ternary blends of cement on the mechanical properties of pervious concrete(PC)specimen through destructive(DT)and non-destructive testing(NDT).Various combinations of fly ash(FA),limestone powder(LP),metakaolin(MK),and silica fume(SF)as mineral admixtures have been investigated to partially replace the cement up to 30%by weight in *** cube specimens of size 150 mm×150 mm×150 mm of binary and ternary blends of mineral admixture of pervious concrete were prepared to conduct standard compressive strength test and split tensile test at 7 and 28 days of *** ultrasonic pulse velocity(UPV)test and Rebound Hammer test were used as a non-destructive testing tool to substantiate the robustness of PC and to determine the approximate mechanical properties where other destructive testing tools are not feasible in case of inplace pervious *** the pervious concrete made with LP based ternary blends(PLM and PLS)were found to perform better than FA based ternary blends(PFM and PFS)and control mix(PC)in destructive and non-destructive testing.

关键词： mineral admixture ternary compressive strength split tensile strength pervious concrete ultrasonic pulse velocity

Recent progress and perspective on batteries made from nuclear waste

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Nuclear Science and Techniques 2023年第3期34卷 1-8页

作者： Nirmal Kumar Katiyar Saurav goel School of Engineering London South Bank UniversityLondonSE10 AAUK University of Petroleum and Energy Studies Dehradun248007India

Sustainable energy sources are an immediate need to cope with the imminent issue of climate change the world is facing *** particular,the long-lasting miniatured power sources that can supply energy continually to power handheld gadgets,sensors,electronic devices,unmanned airborne vehicles in space and extreme mining are some of the examples where this is an acute *** is known from basic physics that radioactive materials decay over few years and some nuclear materials have their half-life until thousands of *** past five decades of research have been spent harnessing the decay energy of the radioactive materials to develop batteries that can last until the radioactive reaction ***,an emergent opportunity of industrial symbiosis to make use of nuclear waste by using radioactive waste as raw material to develop bat-teries with long shelf life presents a great opportunity for sustainable energy resource ***,the current canon of research on this topic is *** perspective draws fresh discussions on the topic while highlighting future directions in this wealthy arena of *** abstract A long-lasting miniaturised nuclear battery utilising 14C radioactive isotope as fuel.

关键词： Sustainable energy Nuclear waste battery Nano-diamond

Cancer immunotherapy in clinical practice—the past,present,and future

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Chinese Journal of Cancer 2014年第9期33卷 445-457页

作者： Gaurav goel Weijing Sun Division of Hematology-Oncology Department of MedicineUniversity of Pittsburgh Cancer Institute University of Pittsburgh School of Medicine

Considerable progress has been made in the field of cancer immunotherapy in recent years. This has been made possible in large part by the identification of new immune-based cellular targets and the development of novel approaches aimed at stimulating the immune system. The role played by the immunosuppressive microenvironment in the development of tumors has been established. The success of checkpoint-inhibiting antibodies and cancer vaccines has marked the beginning of a new era in cancer treatment. This review highlights the clinically relevant principles of cancer immunology and various immunotherapeutic approaches that have either already entered mainstream oncologic practice or are currently in the process of being evaluated in clinical trials. Furthermore, the current barriers to the development of effective immunotherapies and the potential strategies of overcoming them are also discussed.

关键词：癌症治疗免疫疗法临床实践免疫治疗免疫系统临床试验肿瘤学微环境

Phishing website prediction using base and ensemble classifier techniques with cross-validation

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Cybersecurity 2023年第1期6卷 17-39页

作者： Anjaneya Awasthi Noopur goel Department of Computer Applications VBS Purvanchal UniversityJaunpurUPIndia

Internet or public internetwork has become a vulnerable place nowadays as there are so many threats available for the novice or careless users because there exist many types of tools and techniques being used by notorious peo-ple on it to victimize people somehow and gain access to their precious and personal data resulting in sometimes ***,these victims suffer considerable losses in many instances due to their entrapment in such traps as hacking,cracking,data diddling,Trojan attacks,web jacking,salami attacks,and ***,despite the web users and the software and application developer's continuous effort to make and keep the IT infrastructure safe and secure using many techniques,including encryption,digital signatures,digital certificates,*** paper focuses on the problem of phishing to detect and predict phishing websites URLs,primary machine learning classifiers and new ensemble-based techniques are used on 2 distinct *** on a merged dataset,this study is conducted in 3 ***,they include classification using base classifiers,Ensemble classifiers,and then ensemble classifiers are tested with and without ***,their performance is analyzed,and the results are presented at last to help others use this study for their upcoming research.

关键词： Phishing Hacking Data diddling Machine learning Ensemble

The hemispheric asymmetry of solar activity during the last century and the solar dynamo

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Chinese Journal of Astronomy and Astrophysics 2009年第1期9卷 115-126页

作者： Ashish goel Arnab Rai Choudhuri Department of Physics Indian Institute of Technology Department of Physics Indian Institute of Science

We believe the Babcock-Leighton process of poloidal field generation to be the main source of irregularity in the solar cycle. The random nature of this process may make the poloidal field in one hemisphere stronger than that in the other hemisphere at the end of a cycle. We expect this to induce an asymmetry in the next sunspot cycle. We look for evidence of this in the observational data and then model it theoretically with our dynamo code. Since actual polar field measurements exist only from the 1970s, we use the polar faculae number data recorded by Sheeley （1991, 2008） as a proxy of the polar field and estimate the hemispheric asymmetry of the polar field in different solar minima during the major part of the twentieth century. This asymmetry is found to have a reasonable correlation with the asymmetry of the next cycle. We then run our dynamo code by feeding information about this asymmetry at the successive minima and compare the results with observational data. We find that the theoretically computed asymmetries of different cycles compare favorably with the observational data, with the correlation coefficient being 0.73. Due to the coupling between the two hemispheres, any hemispheric asymmetry tends to get attenuated with time. The hemispheric asymmetry of a cycle either from observational data or from theoretical calculations statistically tends to be less than the asymmetry in the polar field （as inferred from the faculae data） in the preceding minimum. This reduction factor turns out to be 0.43 and 0.51 respectively in observational data and theoretical simulations.

关键词： Sun activity -- Sun magnetic fields -- sunspots

Optimal timing for plastic surgical procedures for common congenital anomalies:A review

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World Journal of Clinical Pediatrics 2024年第2期13卷 38-61页

作者： Aakanksha goel Arun goel Divine Aesthetic Surgery New Delhi 110048India Department of Plastic Surgery Lok Nayak Hospital and Associated Maulana Azad Medical CollegeNew Delhi 110002India

Apart from listening to the cry of a healthy newborn,it is the declaration by the attending paediatrician in the labour room that the child is normal which brings utmost joy to *** global incidence of children born with congenital anomalies has been reported to be 3%-6%with more than 90%of these occurring in low-and middle-income group *** exact percentages/total numbers of children requiring surgical treatment cannot be estimated for several *** children are operated under several surgical disciplines,viz,paediatric-,plastic reconstructive,neuro-,cardiothoracic-,orthopaedic surgery *** conditions may be life-threatening,e.g.,trachea-oesophageal fistula,critical pulmonary stenosis,*** require immediate surgical ***,e.g.,hydrocephalus,may need intervention as soon as the patient is fit for ***,e.g.,patent ductus arteriosus need‘wait and watch’policy up to a certain age in the hope of spontaneous *** extremely important category is that of patients where the operative intervention is done based on their *** all the congenital anomalies coming under care of a plastic surgeon are operated as elective surgery(many as multiple stages of correction)at appropriate *** are advantages and disadvantages of intervention at different *** this article,we present a review of optimal timings,along with reasoning,for surgery of many of the common congenital anomalies which are treated by plastic ***,paediatricians and general practitioners/family physicians,who most often are the first ones to come across such children,must know to guide the parents appropriately and convincingly impress upon the them as to why their child should not be operated immediately and also the consequences of too soon or too late.

关键词： Plastic surgery Congenital anomalies Pediatric plastic surgery Facial cleft Microtia Vascular anomalies Syndactyly Hypospadias Optimal timing Pediatric surgery