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Outcomes in randomized controlled trials of exercise interventions in solid organ transplant

World Journal of Transplantation 2016年第4期6卷 774-789页

作者： Tania Janaudis-Ferreira sunita mathur Stacey Konidis Catherine M Tansey Cecile Beaurepaire Canadian National Transplant Research Program School of Physical and Occupational Therapy McGill University Department of Physical Therapy University of Toronto

AIM To identify the outcome measures that have been used in randomized controlled trials(RCTs) of exercise training in solid organ transplant(SOT) recipients and to link these outcomes to the International Classification of Functioning, Disability and Health(ICF) *** Electronic literature searches of MEDLINE, EMBASE, CINAHL, Cochrane, Scopus, and Web of Science were performed. We sought RCTs that investigated the effect of exercise training in SOT recipients. Reference lists of all eligible publications were searched for other appropriate studies not identified by the electronic search. A complete list of outcome measures used in the RCTs was generated and each of these was linked to an ICF *** Four hundred and thirteen articles were retrieved, of which 35 met our inclusion criteria. The studies included were designed to compare the effects of exercise training programs to usual care or to another exercise training program and reported on recipients of heart(n = 21), kidney(n = 9), lung(n = 3) or liver(n = 2) transplant. Of the 126 outcome measures identified, 62 were used as primary outcome measures. The most commonly occurring primary outcomes were aerobic capacity using the peak VO2(n = 13), quality of life using the shortform-36(n = 8), and muscle strength(n = 7). Theseoutcome measures were linked to 113 ICF categories and the majority of outcomes fall into the body function domain(n = 93). CONCLUSION There is little standardization in outcome measures used in RCTs of exercise interventions in SOT recipients. The ICF framework can be used to select a core set of outcomes that cross all domains of ICF and that would be appropriate to all SOT recipients.

关键词： Solid organ transplantation Systematic review Rehabilitation Exercise Outcome measures International Classification of Functioning,Disability and Health

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Physical rehabilitation for lung transplant candidates and recipients: An evidence-informed clinical approach

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World Journal of Transplantation 2016年第3期6卷 517-531页

作者： Lisa Wickerson Dmitry Rozenberg Tania Janaudis-Ferreira Robin Deliva Vincent Lo Gary Beauchamp Denise Helm Chaya Gottesman Polyana Mendes Luciana Vieira Margaret Herridge Lianne G Singer sunita mathur Toronto Lung Transplant Program University Health Network Rehabilitation Services University Health Network Department of Physical Therapy University of Toronto Rehabilitation Sciences Institute University of Toronto School of Physical and Occupational Therapy McGill University Canadian National Transplant Research Program Department of Physiotherapy Hospital for Sick Children Department of General Surgery/Gastroen- terology/Plastics St. Michael’s Hospital Health Sciences and Technologies PhD Program University of Brasilia Faculty of Medicine University of Toronto

Physical rehabilitation of lung transplant candidates and recipients plays an important in optimizing physical function prior to transplant and facilitating recovery of function post-transplant. As medical and surgical interventions in lung transplantation have evolved over time, there has been a demographic shift of individuals undergoing lung transplantation including older individuals, those with multiple co-morbidites, and candidates with respiratory failure requiring bridging to transplantation. These changes have an impact on the rehabilitation needs of lung transplant candidates and recipients. This review provides a practical approach to rehabilitation based on research and clinical practice at our transplant centre. It focuses on functional assessment and exercise prescription during an uncomplicated and complicated clinical course in the pre-transplant, early and late post-transplant periods. The target audience includes clinicians involved in pre- and posttransplant patient care and rehabilitation researchers.

关键词： Lung transplantation Rehabilitation Physical therapy Exercise training Physical activity

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Isolated tuberculous splenic abscess in an immunocompetent individual

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Asian Pacific Journal of Tropical Medicine 2011年第1期4卷 81-82页

作者： Parveen Rana Kundu SK mathur sunita Singh Amrita Duhan Garima Aggarwal Rajeev Sen Department of Pathology Pt.B.D.Sharma PGIMSIndia

Tuberculosis(TB) of the spleen is an extremely rare clinical entity particularly among immunocompetent *** report a case of isolated tuberculous abscess of spleen in a 13- years- old *** primary focus of infection was detected in lungs or any other *** patient was treated by splenectomy after a therapeutic failure with standard antituberculous medication.

关键词： Spleen Tuberculosis Abscess

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