检索结果-南通市图书馆

Nonlinear Time Series Analysis of Pathogenesis of COVID-19 Pandemic Spreadin Saudi Arabia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2021年第1期66卷 805-825页

作者： sunil Kumar sharma Shivam Bhardwaj Rashmi Bhardwaj Majed Alowaidi College of Computer and Information Sciences Majmaah UniversityMajmaah11952Saudi Arabia Maharaja Agrasen Institute of Technology Guru Gobind Singh Indraprastha UniversityDelhi110086India Non-Linear Dynamics Research Laboratory GGS Indraprastha UniversityDelhi110078India

This article discusses short–term forecasting of the novel Corona Virus(COVID-19)data for infected and recovered cases using the ARIMA method for Saudi *** COVID-19 data was obtained from the Worldometer and MOH(Ministry of Health,Saudi Arabia).The data was analyzed for the period from March 2,2020(the first case reported)to June 15,*** ARIMA(2,1,0),we obtained the short forecast up to July 02,*** statistical parameters were tested for the goodness of fit to evaluate the forecasting *** results show that ARIMA(2,1,0)gave a better forecast for the data *** 19 data followed quadratic behavior,and in the long run,it spreads with a high *** is concluded that COVID-19 will follow secondary shock waves,and it is strongly advisable to maintain social distancing with all safety measures as the pandemic situation is not in control.

关键词： COVID-19 short-term forecast ARIMA GIS

Study of plasma parameters of coaxial plasma source using triple Langmuir probe and Faraday cup diagnostics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plasma Science and Technology 2024年第4期26卷 94-100页

作者： sunil KANCHI Rohit SHUKLA Archana sharma Pulsed Power and Electromagnetics Division Bhabha Atomic Research CentreVisakhapatnam 531011India Homi Bhabha National Institute Mumbai 400085India Beam Technology Development Group Bhabha Atomic Research CentreMumbai 400085India

Coaxial plasma guns are a type of plasma source that produces plasma which propagates radially and axially controlled by the shape of the ground electrode, which has attracted much interest in several applications. In this work, a 120° opening angle of CPG nozzle is used as a plasma gun configuration that operates at the energy of 150 J. The ionization of polyethylene insulator between the electrodes of the gun produces a cloud of hydrogen and carbon *** triple Langmuir probe and Faraday cup are used to measure plasma density and plasma temperature. These methods are used to measure the on-axis and off-axis plasma divergence of the coaxial plasma gun. The peak values of ion densities measured at a distance of 25 mm on-axis from the plasma gun are(1.6±0.5)×10^(19)m^(-3)and(2.8±0.6)×10^(19)m^(-3)for hydrogen and carbon plasma respectively and the peak temperature is 3.02±0.5 eV. The mean propagation velocity of plasma is calculated using the transit times of plasma at different distances from the plasma gun and is found to be 4.54±0.25 cm/μs and 1.81±0.18 cm/μs for hydrogen and carbon plasma respectively. The Debye radius is obtained from the measured experimental data that satisfies the thin sheath approximation. The shot-to-shot stability of plasma parameters facilitates the use of plasma guns in laboratory experiments. These types of plasma sources can be used in many applications like plasma opening switches, plasma devices, and as plasma sources.

关键词： coaxial plasma source triple Langmuir probe Faraday cup plasma density plasma temperature

Modelling and Analysis of Bacteria Dependent Infectious Diseases with Variable Contact Rates

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2021年第8期68卷 1859-1875页

作者： J.B.Shukla Shikha Singh Jitendra Singh sunil Kumar sharma Innovative Internet University for Research Kanpur208017India P.P.N.(P.G.)College CSJM UniversityKanpur208001India College of Computer and Information Sciences Majmaah UniversityMajmaah11952Saudi Arabia

In this research,we proposed a non-linear SIS model to study the effect of variable interaction rates and non-emigrating population of the human habitat on the spread of bacteria-infected *** assumed that the growth of bacteria is logistic with an intrinsic growth rate is a linear function of *** this model,we assume that contact rates between susceptibles and infectives as well as between susceptibles and bacteria depend on the density of the non-emigrating population and the total population of the *** stability theory has been analyzed to analyzed to study the crucial role played by bacteria in the increased spread of an infectious *** is shown that as the density of non-emigrating population increases,the spread of an infectious disease *** is shown further that as the emigration increases,the spread of the disease decreases in both the cases of contact mentioned above rates,but this spread increases as these contact rates *** suggested that the control of bacteria in the human habitat is very useful to decrease the spread of an infectious *** results are confirmed by numerical simulation.

关键词： Mathematical modelling density dependent contact rates stability analysis

In vitro evaluation of antimicrobial and antioxidant activities of methanolic extract of Jasminum humile Leaves

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2011年第10期4卷 804-807页

作者： Parminder Nain Ashok Kumar sunil sharma Jaspreet Nain M.M.College of Pharmacy M.M.UniversityMullana(Ambala)-133207India Department of Pharmaceutical sciences Guru Jambeshwer UniversityHisar(Haryana)-125001India

Objective:To evaluate in vitro antimicrobial and antioxidant activities of methanolic extract of Jasminum humile（***） leaves ***:Methanolic extract of *** was evaluated for its antimicrobial activity by using agar well diffusion method & their possible antioxidant assay by two complementary test systems,namely DPPH and hydrogen peroxide scavenging *** various antioxidant activities were compared to standard antioxidants such as ascorbic acid for both the ***:In the DPPH & hydrogen peroxide scavenging activity,the IC50 value of methanol extract was 70.43μg/mL & 60.79μg/mL respectively. Further,the extract showed inhibitory activity for Gram-positive and negative bacteria at different *** maximum antibacterial activity of extract was exhibited against Staphylococcus aureus（***） at concentration 50 mg/mL when compared with ciprofloxacin Conclusions:These results clearly indicate that *** is effective in scavenging free radicals and has the potential to be a powerful ***,the results obtained in the present study indicate that *** leaves extract could be considered as a potential source of natural antioxidants and that could be used as an effective source against bacterial diseases.

关键词： Jasminum humile Methanol extract Antimicrobial activity Antioxidant activity

Structural characterization of carboxyl cellulose nanofibers extracted from underutilized sources

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2019年第6期62卷 971-981页

作者： ZHAN ChengBo sharma Priyanka R. GENG LiHong sharma sunil K. WANG RuiFu JOSHI Ritika HSIAO Benjamin S. Department of Chemistry Stony Brook University Stony Brook NY 11794-3400 USA National Engineer Research Center of Novel Equipment for Polymer Processing Key Laboratory of Polymer Processing Engineering of Ministry of Education South China University of Technology Guangzhou 510640 China

Two different chemical methods, TEMPO-oxidation and nitro-oxidation, were used to extract carboxyl cellulose nanofibers(CNFs) from non-wood biomass sources(i.e., jute, soft and hard spinifex grasses). The combined TEMPO-oxidation and homogenization approach was very efficient to produce CNFs from the cellulose component of biomass;however, the nitrooxidation method was also found to be effective to extract CNFs directly from raw biomass even without mechanical *** effect of these two methods on the resulting cross-section dimensions of CNFs was investigated by solution small-angle Xray scattering(SAXS), transmission electron microscopy(TEM) and atomic force microscopy(AFM). The UV-Vis spectroscopic data from 0.1 wt% TEMPO-oxidized nanofiber(TOCNF) and nitro-oxidized nanofiber(NOCNF) suspensions showed that TOCNF had the highest transparency(> 95%) because of better dispersion, resulted from the highest carboxylate content(1.2 mmol/g). The consistent scattering and microscopic results indicated that TOCNFs from jute and spinifex grasses possessed rectangular cross-sections, while NOCNFs exhibited near square cross-sections. This study revealed that different oxidation methods can result in different degrees of biomass exfoliation and different CNF morphology.

关键词： cellulose nanofibers TEMPO-oxidation nitro-oxidation SAXS microscopy jute spinifex

IoT-Based Women Safety Gadgets (WSG): Vision, Architecture, and Design Trends

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2023年第7期76卷 1027-1045页

作者： Sharad Saxena Shailendra Mishra Mohammed Baljon Shamiksha Mishra sunil Kumar sharma Prakhar Goel Shubham Gupta Vinay Kishore Department of Computer Science and Engineering Thapar Institute of Engineering and TechnologyPatialaPunjab147001India Department of Computer Engineering College of Computer&Information ScienceMajmaah UniversityMajmaah11952Saudi Arabia Department of Computer Science and Engineering National Institute of TechnologyJamshedpur831001India

In recent years,the growth of female employees in the commercial market and industries has *** a result,some people think travelling to distant and isolated locations during odd hours generates new threats to women’s *** exponential increase in assaults and attacks on women,on the other hand,is posing a threat to women’s growth,development,and *** the time of the attack,it appears the women were immobilized and needed immediate *** self-defense isn’t sufficient against abuse;a new technological solution is desired and can be used as quickly as hitting a switch or *** proposed Women Safety Gadget(WSG)aims to design a wearable safety device model based on Internet-of-Things(IoT)and Cloud *** is designed in three layers,namely layer-1,having an android app;layer-2,with messaging and location tracking system;and layer-3,which updates information in the cloud *** can detect an unsafe condition by the pressure sensor of the finger on the artificial nail,consequently diffuses a pepper spray,and automatically notifies the saved closest contacts and police station through messaging and location *** has a response time of 1000 ms once the nail is pressed;the average time for pulse rate measure is 0.475 s,and diffusing the pepper spray is 0.2–0.5 *** average activation time is 2.079 s.

关键词： Perpetrator safety IoT women security GPS tracking GSM

Gene silencing of E-selectin block recruitment of endothelial progenitor cell to vascular endothelium under flow

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Biomedical Science and Engineering 2010年第6期3卷 350-355页

作者： sunil sharma Masayuki Yoshida 不详

Short interfering RNA (siRNA) is a powerful technique that can suppress gene expression in a variety of cells including mammalian cells. Endothelial progenitor cells (EPCs) are bone marrow—derived haematopoietic progenitor cells that have been implicated in vasculogenesis. We demonstrated for the first time that gene silencing of endothelial E-selectin using siRNA transfection in human umbilical vein endothelial cells (HUVECs) causes inhibition of EPC adhesion under flow conditions. Fluorescence immunobinding assay analysis showed that significant reduction of E-selectin surface expression in HUVECs (activated with IL-1β (10 U/mL) for 4 h) transfected with siRNA against E-selectin, but not in HUVECs transfected with LacZ siRNA (control). An EPC adhesion assay under flow conditions (shear stress = 1.0 dyne/cm2) then demonstrated that HUVECs transfected with E-selectin siRNA supported significantly less adhesion of EPCs than those HUVECs treated with control siRNA and no siRNA after activation by IL-1β (p <0.05). Our experiments have shown the importance of E-selectin in EPC adhesion to HUVECs and the potential utility of gene silencing of E-selectin in EPC recruitment.

关键词： Endothelial Progenitor Cell E-Selectin Rnai

Microbiological Treatment of Effluent for Zinc Hydrometallurgical Plant

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Chemistry and Chemical Engineering 2014年第4期8卷 400-407页

作者： Ashish Kumar Krishna Deo sharma sunil Duggal Central R&D Laboratory Hindustan Zinc Limited Udaipur 313024 India

Sulfate reducing bacteria were isolated from the soil sample of Roaster-Acid unit of Debari Zinc Smelter of Hindustan Zinc Ltd., India and were adapted for effluent water of Zinc hydrometallurgy plant to sustain zinc concentration of about 500 ppm and iron concentration of about 160 ppm with high acidity （pH 〈 1.0）. Nutrient broth, whey, ethanol and sucrose were tested as carbon source for SRB （sulfate reducing bacteria） out of which whey was found as the best electron donor to expedite the rate of biological treatment with SRB. A two stage anaerobic bioreactor was developed with a treatment capacity of 30 L effluent water in 4 days. The concentration of heavy metals in the treated water was within the permissible limits. The suggested methodology generates no solid waste, is environment friendly and may be commercially implemented for treatment of zinc plant effluent.

关键词： Sulfate reducing bacteria anaerobic treatment isolation hydrometallurgy effluent.

BACE1 inhibitors:A promising therapeutic approach for the management of Alzheimer’s disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2024年第9期14卷 369-381页

作者： Richa Arya Smita Jain Sarvesh Paliwal Kirtika Madan Swapnil sharma Achal Mishra Prashant Tiwari sunil Kumar Kadiri Banasthali University Banasthali-304022(Raj.)India Department of Pharmacy Guru Ghasidas VishwavidyalayaBilaspurChhattisgarh-495009India Department of Pharmacology College of Pharmaceutical SciencesDayananda Sagar UniversityBengaluru-560111India

Alzheimer’s disease is a neurological disorder marked by the accumulation of amyloid beta(Aβ)aggregates,resulting from mutations in the amyloid precursor *** enzymeβ-secretase,also known asβ-site amyloid precursor protein cleaving enzyme 1(BACE1),plays a crucial role in generating Aβ*** no targeted therapy available for Alzheimer’s disease,inhibiting BACE1 aspartic protease has emerged as a primary treatment *** 1999,compounds demonstrating potential binding to the BACE1 receptor have advanced to human *** optimization of synthetically derived compounds,coupled with computational approaches,has offered valuable insights for developing highly selective leads with drug-like *** review highlights pivotal studies on the design and development of BACE1 inhibitors as anti-Alzheimer’s disease *** summarizes computational methods employed in facilitating drug discovery for potential BACE1 inhibitors and provides an update on their clinical status,indicating future directions for novel BACE1 *** promising clinical results of Elenbecestat(E-2609)catalyze the development of effective,selective BACE1 inhibitors in the future.

关键词： BACE1 inhibitors Amyloid precursor protein β-secretase Structure-based drug design 3D-QSAR β-amyloid precursor protein